Cancer gene determination and therapeutic screening using signature gene sets

ABSTRACT

Processes for assaying potential antitumor agents based on their modulation of the expression of specified genes, or sets, of suspected cancer cell genes, especially for pancreatic cancer, are disclosed, along with methods for diagnosing cancerous, or potentially cancerous, conditions as a result of the expression, or patterns of expression, of such genes, or sets of genes. Also disclosed are methods for determining functionally related genes, or gene sets, as well as methods for treating cancer based on targeting expression products of such genes, or gene sets, and determining genes involved in the cancerous process.

[0001] This application claims priority of U.S. Provisional Application60/237,598, filed Oct. 3, 2000 and No. 60/237,604, filed Oct. 3, 2000,the disclosures of which are hereby incorporated by reference in theirentirety.

FIELD OF THE INVENTION

[0002] The present invention relates to methods of assaying potentialanti-tumor agents based on their modulation of the expression ofspecified sets of genes and methods for diagnosing cancerous, orpotentially cancerous, conditions as a result of the patterns ofexpression of such genes.

BACKGROUND OF THE INVENTION

[0003] Screening assays for novel drugs are based on the response ofmodel cell based systems in vitro to treatment with specific compounds.Various measures of cellular response have been utilized, including therelease of cytokines, alterations in cell surface markers, activation ofspecific enzymes, as well as alterations in ion flux and/or pH. Somesuch screens rely on specific genes, such as oncogenes (or genemutations).

BRIEF SUMMARY OF THE INVENTION

[0004] In accordance with the present invention, there are providedcharacteristic sets of gene sequences whose expression, ornon-expression, or change in expression, either an increase or decreasethereof, are indicative of the cancerous or non-cancerous status of agiven cell, especially pancreas. More particularly, such genes whoseexpression is changed in cancerous, as compared to non-cancerous cells,from a specific tissue (in particular, pancreas) are genes that includeone of the nucleotide sequences of SEQ ID NO: 1-318, or sequences thatare substantially identical to, or incorporated in, these sequences.Such a change in expression may be an increase or a decrease inexpression or activity of the gene or gene sequences disclosed herein.

[0005] It is another object of the present invention to provide methodsof using such characteristic, or signature, gene sets as a basis forassaying the potential ability of selected chemical agents to modulateupward or downward the expression of said characteristic, or signature,gene sets.

[0006] It is a further object of the present invention to providemethods of detecting the expression, or non-expression, or amount ofexpression, of said characteristic, or signature, gene sets, or portionsthereof, as a means of determining the cancerous, or non-cancerous,status (or potential cancerous status) of selected cells as grown inculture or as maintained in situ.

[0007] It is a still further object of the present invention to providemethods for treating cancerous conditions utilizing selected chemicalagents as determined from their ability to modulate (i.e., increase ordecrease) the selected characteristic, or signature, gene sets asdisclosed herein, where said genes include, or comprise, one of thesequences of SEQ ID NO: 1-318, or sequences substantially identical tosaid sequences, or characteristic portions of said sequences.

[0008] In one aspect, the present invention relates to a process foridentifying an agent that modulates the activity of a cancer-relatedgene comprising:

[0009] (a) contacting a compound with a cell containing a genecorresponding to (such as a gene that encodes an RNA at least 90%identical to the RNA encoded by or complementary to) a polynucleotidecomprising, or having, a sequence selected from the group consisting ofSEQ ID NO: 1-318 and under conditions promoting the expression of saidgene; and

[0010] (b) detecting a difference in expression of said gene relative towhen said compound is not present

[0011] thereby identifying an agent that modulates the activity of acancer-related gene. Such a process is especially useful for agentseffective against cancer of the pancreas, including carcinomas,especially adenocarcinoma.

[0012] The present invention also relates to a process for identifyingan anti-neoplastic agent comprising contacting a cell exhibitingneoplastic activity with a compound first identified as a cancer-relatedgene modulator using an assay process as disclosed herein fordetermining gene modulating activity and detecting a decrease in saidneoplastic activity after said contacting compared to when saidcontacting does not occur.

[0013] In a further aspect, the present invention relates to a processfor identifying an anti-neoplastic or anti-tumor agent comprisingadministering to an animal exhibiting a cancerous condition an effectiveamount of an agent first identified according to a process as disclosedherein and detecting a decrease in said cancerous condition therebyidentifying such an agent, said decrease including the death of thecancerous cell or cells.

[0014] The present invention also relates to a process for determiningthe cancerous status of a cell, comprising determining the level ofexpression in said cell of at least one gene that corresponds to apolynucleotide comprising, or having, a sequence selected from the groupconsisting of SEQ ID NO: 1-318 wherein an elevated expression relativeto a known non-cancerous cell when the sequence is one of SEQ ID NO:230-318 or a reduced expression relative to a known non-cancerous cellwhen the sequence is one of SEQ ID NO: 1-229, indicates a cancerousstate or potentially cancerous state. Such sequence identity may include100 percent identical as defined herein and any number of such genes maybe used. Said non-cancerous cell is preferably a pancreas cell.

[0015] In an additional aspect, the present invention relates to aprocess for determining a cancer initiating or facilitating genecomprising contacting a cell expressing a test gene (i.e., a gene whosestatus as a cancer initiating or facilitating gene is to be determined)with an agent that decreases the expression of a gene that encodes anRNA at least 90%, preferably 95%, identical to an RNA encoded by (i.e.,a gene corresponding to) a polynucleotide comprising, or having, asequence selected from the group consisting of SEQ ID NO: 230-318 anddetecting a decrease in expression of said test gene compared to whensaid agent is not present, thereby identifying said test gene as being acancer initiating or facilitating gene. Such genes may, of course, beoncogenes and said decrease in expression may be due to a decrease incopy number of said gene in said cell or a cell derived from said cell,such as where copy number is reduced in the cells formed by replicationof such cells.

[0016] The present invention also relates to a process for determining acancer suppressor gene comprising contacting a cell expressing a testgene (i.e., a gene whose status as a cancer suppressor gene is to bedetermined) with an agent that increases the expression of a gene thatcorresponds to (i.e., encodes an RNA at least 90%, preferably 95%,identical to an RNA encoded by or complementary to) a polynucleotidecomprising a sequence selected from the group consisting of SEQ ID NO:1-229 and detecting an increase in expression of said test gene comparedto when said agent is not present, thereby identifying said test gene asbeing a cancer suppressor gene. The sequence identity may includeidentical sequences, as defined herein, and such a process includesembodiments wherein the increase in expression is due to an increase incopy number of the gene in said cell or a cell derived from said cell,such as following cellular replication.

[0017] In another aspect, the present invention relates to a process fortreating cancer comprising contacting a cancerous cell with an agenthaving activity against an expression product encoded by a genecorresponding to a polynucleotide comprising a nucleotide sequenceselected from at least one of SEQ ID NO: 230-318. Such a processincludes an embodiment wherein the cancerous cell is contacted in vivo.The agent may include an antibody. In a preferred embodiment, the canceris cancer of the pancreas, especially a carcinoma, most preferablyadenocarcinoma.

[0018] The present invention also relates to a method for producing aproduct comprising identifying an agent according to the assay processesof the invention wherein said product is the data collected with respectto said agent as a result of said process and wherein said data issufficient to convey the chemical structure and/or properties of saidagent.

[0019] The present invention further relates to a process for treating acancerous condition in an animal afflicted therewith comprisingadministering to said animal a therapeutically effective amount of anagent first identified as having anti-neoplastic activity using one ormore of the processes of the invention.

[0020] In a further aspect, the present invention relates to a processfor protecting an animal against cancer comprising administering to ananimal at risk of developing cancer a therapeutically effective amountof an agent first identified as having anti-neoplastic activity usingone or more of the processes disclosed herein.

DETAILED SUMMARY OF THE INVENTION

[0021] The present invention relates to methods of assaying forpotential antitumor agents based on their modulation of the expressionof specified sets of genes and methods for diagnosing cancerous, orpotentially cancerous, conditions, especially of pancreas, as a resultof the patterns of expression of such gene sets and for determiningcancer-inducing or regulating genes, and gene sets, based on commonexpression or regulation of such genes, or gene sets.

[0022] In accordance with the present invention, model cellular systemsusing cell lines, primary cells, or tissue samples are maintained ingrowth medium and may be treated with compounds that may be at a singleconcentration or at a range of concentrations. At specific times aftertreatment, cellular RNAs are isolated from the treated cells, primarycells or tumors, which RNAs are indicative of expression of selectedgenes. The cellular RNA is then divided and subjected to analysis thatdetects the presence and/or quantity of specific RNA transcripts, whichtranscripts may then be amplified for detection purposes using standardmethodologies, such as, for example, reverse transcriptase polymerasechain reaction (RT-PCR), etc. The presence or absence, or levels, ofspecific RNA transcripts are determined from these measurements and ametric derived for the type and degree of response of the sample to thetreated compound compared to control samples.

[0023] Also in accordance with the present invention, there aredisclosed herein characteristic, or signature, sets of genes and genesequences whose expression is, or can be, as a result of the methods ofthe present invention, linked to, or used to characterize, thecancerous, or non-cancerous, status of the cells, or tissues, to betested, especially tissues derived from pancreas (i.e., cancer-relatedgenes and gene sequences). Thus, the methods of the present inventionidentify novel anti-neoplastic agents based on their alteration ofexpression of small sets of characteristic, or indicator, or signaturegenes in specific model systems. The methods of the invention maytherefore be used with a variety of cell lines or with primary samplesfrom tumors maintained in vitro under suitable culture conditions forvarying periods of time, or in situ in suitable animal models.

[0024] More particularly, certain genes have been identified that areexpressed at levels in cancer cells that are different than theexpression levels in non-cancer cells. In one instance, the identifiedgenes are expressed at higher levels in cancer cells than in normalcells. In another instance, the identified genes are expressed at lowerlevels in cancer cells as compared to normal cells.

[0025] In accordance with the foregoing, the present invention relatesto a process for determining the cancerous status of a cell, comprisingdetermining the level of expression in said cell of at least one genethat corresponds to (i.e., encodes an RNA at least 95% identical to theRNA encoded by or complementary to) a polynucleotide comprising asequence selected from the group consisting of SEQ ID NO: 1-318 whereinan elevated expression relative to a known non-cancerous cell when thesequence is one of SEQ ID NO: 230-318, or a reduced expression relativeto a known non-cancerous cell when the sequence is one of SEQ ID NO:1-229, indicates a cancerous state or potentially cancerous state. Suchsequence identity may include 100 percent identical as defined hereinand any number of such genes may be used.

[0026] Thus, the present invention also relates to a process foridentifying an anti-neoplastic agent comprising contacting a cellexhibiting neoplastic activity with a compound first identified as acancer-related gene modulator using an assay process as disclosed hereinfor determining gene modulating activity and detecting a decrease insaid neoplastic activity after said contacting compared to when saidcontacting does not occur (i.e., comparing expression when said agent ispresent versus when said agent is not present).

[0027] In preferred embodiments of the present invention, such cancer ispancreatic cancer, such as a carcinoma, preferably adenocarcinoma.

[0028] In a further aspect, the present invention relates to a processfor identifying an anti-neoplastic agent comprising administering to ananimal exhibiting a cancerous condition an effective amount of an agentfirst identified as having such activity using a process as disclosedherein and detecting a decrease in said cancerous condition therebyidentifying such an agent.

[0029] It should be kept in mind that the anti-tumor or anti-neoplasticagents identified by the processes of the invention include both novelagents whose structure and anti-tumor activity were not previously knownprior to identification of their activity by the processes herein aswell as non-novel agents, whose structure was known but whosetherapeutic value as anti-tumor agents was not appreciated prior toidentification by the assay processes of the invention.

[0030] In accordance with the foregoing, the present invention relatesto a process for screening for an anti-neoplastic agent comprising thesteps of:

[0031] (a) contacting a compound with a cell containing a polynucleotidecomprising a nucleotide sequence selected from the group consisting ofSEQ ID NO: 1-318, or a sequence at least 90%, preferably at least 95%,identical thereto, under conditions wherein said polynucleotide is beingexpressed, and

[0032] (b) determining a change in expression of at least one of saidpolynucleotides,

[0033] wherein a change in expression is indicative of anti-neoplasticactivity.

[0034] In particular embodiments, such change in expression may be anincrease or a decrease in expression or activity. Of course, decreasedexpression of cancer initiating or facilitating genes is highlydesirable, as is an increased expression of cancer suppressor genes.

[0035] More particularly, the present invention relates to a process forscreening for an anti-neoplastic agent comprising the steps of:

[0036] (a) exposing a known cancerous cell to a chemical agent to betested for antineoplastic activity;

[0037] (b) allowing said chemical agent to modulate the activity of oneor more genes present in said cell wherein said genes include orcomprise one of the sequences selected from the group consisting of thesequences of SEQ ID NO: 1 -318, sequences substantially identical tosaid sequences, or the complements of any of the foregoing;

[0038] (c) determining the expression of one or more genes of step (b);

[0039] (d) comparing the expression of said genes in the presence orabsence of exposure to said chemical agent;

[0040] wherein a difference in expression is indicative of the abilityof anti-neoplastic activity.

[0041] Thus, in one aspect, the present invention relates to a processfor identifying an agent, such as an organic compound, that modulatesthe activity of a cancer-related gene, such as cancer of the pancreas,comprising:

[0042] (a) contacting a compound with a cell containing a gene thatencodes an RNA at least 90%, preferably at least 95%, identical to theRNA encoded by (i.e., a gene that corresponds to) a polynucleotidecomprising, or having, a sequence selected from the group consisting ofSEQ ID NO: 1-318 and under conditions promoting the expression of saidgene; and

[0043] (b) detecting a difference in expression of said gene relative towhen said compound is not present

[0044] thereby identifying an agent that modulates the activity of acancer-related gene.

[0045] Such sequence identity includes embodiments wherein the RNAs areat least 97 or 98% identical in sequence as well as cases where thesequence is the same, thus where a gene encodes an RNA with the samenucleotide sequence as an RNA encoded by one of the sequences of SEQ IDNO: 1-318.

[0046] In one embodiment of such processes, the sequence is selectedfrom SEQ ID NO: 230-318, and said difference in expression when saidagent is present is a decrease in expression. Here, the gene usedencodes an RNA like that encoded by (or at least 90% identical to) oneof the sequences found to be expressed at an elevated level in cancercells, especially pancreas cancer cells. In another such embodiment, thesequence is selected from SEQ ID NO: 1-229 and said difference inexpression is an increase in expression. The latter sequences encodeRNAs found to be expressed at higher levels in normal cells, such aspancreas cells, as opposed to cancer cells.

[0047] In specific embodiments of the present invention, said chemicalagent to be tested modulates the expression of more than one said gene,especially where it modulates at least two said genes, more especiallywhere at least 3, or at least 5 of said genes, or even 10 or more ofsaid genes in said signature set, are modulated. In a preferredembodiment, this may include more than 10 (such as 20, 50 or even 100)or even all of said genes are modulated.

[0048] In one embodiment of the present invention, said gene modulationis downward modulation, so that, as a result of exposure to the chemicalagent to be tested, one or more genes of the cancerous cell will beexpressed at a lower level (or not expressed at all) when exposed to(i.e., contacted with) the agent as compared to the expression when notexposed to the agent (i.e., when said agent is not present).

[0049] In a preferred embodiment a selected set of said genes areexpressed in the reference cell but not expressed in the cell to betested as a result of the contacting or exposure of the test cell withthe chemical agent. Thus, where said chemical agent causes the gene, orgenes, of the tested cell to be expressed at a lower level than the samegenes of the reference cell, this is indicative of downward modulationand indicates that the chemical agent to be tested has anti-neoplasticactivity (or activity in reducing expression of such cancer-relatedgenes).

[0050] In a separate embodiment, exposure of said cells to be tested tothe chemical agent, especially one suspected of having anti-neoplasticactivity, may result in upward modulation of said genes of the cell tobe tested. Such upward modulation is interpreted as meaning that saidgenes are expressed where previously not expressed, or else areexpressed in greater quantities, or at higher levels, when exposed tothe agent as compared to non-exposure to the agent. Such upwardmodulation may be taken as indicative of anti-neoplastic activity by thetested chemical agent(s) of the gene, or genes, so modulated, resultingin lower neoplastic activity on the part of such cells, such as whereincreased expression of the gene, or genes, results in decreased growthand/or increased differentiation of said cells away from the cancerousstate.

[0051] The genes useful in the assay processes include as a part thereofat least one of the sequences selected from the group consisting of thesequences of SEQ ID NO: 1-318, or sequences substantially identicalthereto. Such sequences also include sequences complementary to any ofthe sequences disclosed herein.

[0052] The genes identified by the present disclosure are considered“cancer-related” genes, as this term is used herein, and include genesexpressed at higher levels (due, for example, to elevated rates ofexpression, elevated extent of expression or increased copy number) incancer cells relative to expression of these genes in normal (i.e.,non-cancerous) cells where said cancerous state or status of test cellsor tissues has been determined by methods known in the art, such as byreverse transcriptase polymerase chain reaction (RT-PCR) as described inthe Example below. In specific embodiments, this relates to the geneswhose sequences correspond to the sequences of SEQ ID NO: 230-318. Alsospecifically contemplated are genes whose expression is higher in normalas opposed to known cancer cells (as determined by other means, such asuncontrolled growth, change in antigenic surface proteins, geneticmutation, and the like) such that the decreased expression in cancercells may be indicative of, or contributory to, the realization of thecancerous state. In specific embodiments thereof, this relates to thegenes whose sequences correspond to the sequences of SEQ ID NO: 1-229disclosed herein. As used herein, the term “correspond” means that thegene has the indicated nucleotide sequence or that it encodessubstantially the same RNA as would be encoded by the indicatedsequence, the term “substantially” meaning about at least 90% identicalas defined elsewhere herein and includes splice variants thereof.

[0053] The sequences disclosed herein may be genomic in nature and thusrepresent the sequence of an actual gene, such as a human gene, or maybe a cDNA sequence derived from a messenger RNA (mRNA) and thusrepresent contiguous exonic sequences derived from a correspondinggenomic sequence or they may be wholly synthetic in origin for purposesof tecting. As described in the Example, the expression of thesecancer-related genes is determined from the relative expression levelsof the RNA complement of a cancerous cell relative to a normal (i.e.,non-cancerous) cell. Because of the processing that may take place intransforming the initial RNA transcript into the final mRNA, thesequences disclosed herein may represent less than the full genomicsequence. They may also represent sequences derived from ribosomal andtransfer RNAs. Consequently, the genes present in the cell (andrepresenting the genomic sequences) and the sequences disclosed herein,which are mostly cDNA sequences, may be identical or may be such thatthe cDNAs contain less than the full genomic sequence. Such genes andcDNA sequences are still considered corresponding sequences because theyboth encode similar RNA sequences. Thus, by way of non-limiting exampleonly, a gene that encodes an RNA transcript, which is then processedinto a shorter mRNA, is deemed to encode both such RNAs and thereforeencodes an RNA complementary to (using the usual Watson-Crickcomplementarity rules), or that would otherwise be encoded by, a cDNA(for example, a sequence as disclosed herein). Thus, the sequencesdisclosed herein correspond to genes contained in the cancerous ornormal cells used to determine relative levels of expression becausethey represent the same sequences or are complementary to RNAs encodedby these genes. Such genes also include different alleles and splicevariants that may occur in the cells used in the processes of theinvention.

[0054] The genes of the invention “correspond to” a polynucleotidehaving a sequence of SEQ ID NO: 1-318 if the gene encodes an RNA(processed or unprocessed, including naturally occurring splice variantsand alleles) that is at least 90% identical, preferably at least 95%identical, most preferably at least 98% identical to, and especiallyidentical to, an RNA that would be encoded by, or be complementary to,such as by hybridization with, a polynucleotide having the indicatedsequence. In addition, genes including sequences at least 90% identicalto a sequence selected from SEQ ID NO: 1-318, preferably at least about95% identical to such a sequence, more preferably at least about 98%identical to such sequence and most preferably comprising such sequenceare specifically contemplated by all of the processes of the presentinvention as being genes that correspond to these sequences. Inaddition, sequences encoding the same proteins as any of thesesequences, regardless of the percent identity of such sequences, arealso specifically contemplated by any of the methods of the presentinvention that rely on any or all of said sequences, regardless of howthey are otherwise described or limited. Thus, any such sequences areavailable for use in carrying out any of the methods disclosed accordingto the invention. Such sequences also include any open reading frames,as defined herein, present within any of the sequences of SEQ ID NO: 1-318.

[0055] Further in accordance with the present invention, the term“percent identity” or “percent identical,” when referring to a sequence,means that a sequence is compared to a claimed or described sequenceafter alignment of the sequence to be compared (the “Compared Sequence”)with the described or claimed sequence (the “Reference Sequence”). ThePercent Identity is then determined according to the following formula:

Percent Identity=100[1−(C/R)]

[0056] wherein C is the number of differences between the ReferenceSequence and the Compared Sequence over the length of alignment betweenthe Reference Sequence and the Compared Sequence wherein (i) each baseor amino acid in the Reference Sequence that does not have acorresponding aligned base or amino acid in the Compared Sequence and(ii) each gap in the Reference Sequence and (iii) each aligned base oramino acid in the Reference Sequence that is different from an alignedbase or amino acid in the Compared Sequence, constitutes a difference;and R is the number of bases or amino acids in the Reference Sequenceover the length of the alignment with the Compared Sequence with any gapcreated in the Reference Sequence also being counted as a base or aminoacid.

[0057] If an alignment exists between the Compared Sequence and theReference Sequence for which the percent identity as calculated above isabout equal to or greater than a specified minimum Percent Identity thenthe Compared Sequence has the specified minimum percent identity to theReference Sequence even though alignments may exist in which thehereinabove calculated Percent Identity is less than the specifiedPercent Identity.

[0058] As used herein, the terms “portion,” “segment,” and “fragment,”when used in relation to polypeptides, refer to a continuous sequence ofnucleotide residues, sequence forms a subset of a larger sequence. Suchterms include the products produced by treatment of said polynucleotideswith any of the common endonucleases, or any stretch of polynucleotidesthat could be synthetically synthesized. These may include exonic andintronic sequences of the corresponding genes.

[0059] As used herein and except as noted otherwise, all terms aredefined as given below.

[0060] In accordance with the present invention, the term “DNA segment”or “DNA sequence” refers to a DNA polymer, in the form of a separatefragment or as a component of a larger DNA construct, which has beenderived from DNA isolated at least once in substantially pure form,i.e., free of contaminating endogenous materials and in a quantity orconcentration enabling identification, manipulation, and recovery of thesegment and its component nucleotide sequences by standard biochemicalmethods, for example, using a cloning vector. Such segments are providedin the form of an open reading frame uninterrupted by internalnontranslated sequences, or introns, which are typically present ineukaryotic genes. Sequences of non-translated DNA may be presentdownstream from the open reading frame, where the same do not interferewith manipulation or expression of the coding regions.

[0061] The term “coding region” refers to that portion of a gene whicheither naturally or normally codes for the expression product of thatgene in its natural genomic environment, i.e., the region coding in vivofor the native expression product of the gene. The coding region can befrom a normal, mutated or altered gene, or can even be from a DNAsequence, or gene, wholly synthesized in the laboratory using methodswell known to those of skill in the art of DNA synthesis.

[0062] In accordance with the present invention, the term “nucleotidesequence” refers to a heteropolymer of deoxyribonucleotides. Generally,DNA segments encoding the proteins provided by this invention areassembled from cDNA fragments and short oligonucleotide linkers, or froma series of oligonucleotides, to provide a synthetic gene which iscapable of being expressed in a recombinant transcriptional unitcomprising regulatory elements derived from a microbial or viral operon.

[0063] The term “expression product” means that polypeptide or proteinthat is the natural translation product of the gene and any nucleic acidsequences coding equivalents resulting from genetic code degeneracy andthus coding for the same amino acid(s).

[0064] The term “fragment,” when referring to a coding sequence, means aportion of DNA comprising less than the complete coding region whoseexpression product retains essentially the same biological function oractivity as the expression product of the complete coding region.

[0065] The term “primer” means a short nucleic acid sequence that ispaired with one strand of DNA and provides a free 3′-OH end at which aDNA polymerase starts synthesis of a deoxyribonucleotide chain. Theseinclude PCR primers.

[0066] The term “promoter” means a region of DNA involved in binding ofRNA polymerase to initiate transcription. The term “enhancer” refers toa region of DNA that, when present and active, has the effect ofincreasing expression of a different DNA sequence that is beingexpressed, thereby increasing the amount of expression product formedfrom said different DNA sequence.

[0067] The term “open reading frame (ORF)” means a series of tripletscoding for amino acids without any termination codons and is a sequence(potentially) translatable into protein.

[0068] As used herein, reference to a DNA sequence includes both singlestranded and double stranded DNA. Thus, the specific sequence, unlessthe context indicates otherwise, refers to the single strand DNA of suchsequence, the duplex of such sequence with its complement (doublestranded DNA) and the complement of such sequence.

[0069] In carrying out the assays of the invention, relativeantineoplastic activity may be ascertained by the extent to which agiven chemical agent modulates the expression of genes present in acancerous cell. Thus, a first chemical agent that modulates theexpression of a gene associated with the cancerous state (i.e., a genethat includes one of the sequences disclosed herein and present incancerous cells) to a larger degree than a second chemical agent testedby the assays of the invention is thereby deemed to have higher, or moredesirable, or more advantageous, anti-neoplastic activity than saidsecond chemical agent. Alternatively, where first and second chemicalagents modulate expression of more than one of said genes, but where thesecond modulates expression of, for example, five said genes, whereasthe first modulates expression of only three of said genes, especiallywhere the three form a subset of the five, then the second chemicalagent is deemed a more potent anti-neoplastic agent than the first. Suchanti-neoplastic activity, as determined using the assays of the presentinvention, may necessarily include combinations of the foregoingpossibilities, which are in no way to be considered limiting.

[0070] In utilizing these gene sequences for the assays according to theinvention, the genes whose activity is to be determined with and withoutthe presence of the compound to be evaluated for anti-tumor activity maybe any one, or several, or any combination of the gene sequencesdisclosed herein as SEQ ID NO: 1-318. However, how the gene sequencesare employed in such assays depends on the pattern of gene expressiondisclosed for the signature sets. For example, a sequence that isexpressed in cancerous cells but not in normal cells will identify apotential anticancer agent by that agent's ability to decreaseexpression of the sequence, or sequences, in tumor cells. Conversely, asequence, or sequences, expressed in normal but not tumor cells willidentify a potential antitumor agent by its ability to increaseexpression of those genes in the tumor cells. The same relationshipholds true where the sequences are expressed in both cancer and normalcells but are expressed at a higher level in one than in the other, andvice versa. Based on the expression patterns disclosed for the genesequences and signature sets disclosed herein, it should be readilyapparent to those skilled in the art how to conduct assays for potentialantitumor agents using the signature gene sets. The same holds truewhere the sequences, or signature gene sets, are utilized to determinethe cancerous state of a cell or use of an agent to treat a cancerouscondition.

[0071] Thus, in one aspect, the present invention relates to a processfor screening for an anti-neoplastic agent comprising the steps of (a)exposing cells to a chemical agent to be tested for antineoplasticactivity, and (b) determining a change in expression of at least onegene of a signature gene set, or a sequence that is at least 90%,preferably at least 95% identical thereto, wherein a change inexpression is indicative of anti-neoplastic activity. Such change inexpression is intended to mean a change that includes any activity ofthe gene, and may be an increase or decrease thereof. In addition, suchchange in activity may be a change in expression or other activity of atleast 1 such gene, such as 5 or 10, or more of the genes of a signatureset, even as many as half of such genes or even of all of the genes of aparticular gene set.

[0072] The gene expression to be measured is commonly assayed using RNAexpression as an indicator. Thus, the greater the level of RNA (such asa messenger RNA) detected the higher the level of expression of thecorresponding gene. Thus, gene expression, either absolute or relative,such as where the expression of several different genes are beingquantitatively evaluated and compared, for example, where chemicalagents modulate the expression of more than one gene, such as a set of3, 4, 5, or more genes, is determined by the relative expression of theRNAs encoded by such genes.

[0073] RNA may be isolated from samples in a variety of ways, includinglysis and denaturation with a phenolic solution containing a chaotropicagent (e.g., triazol) followed by isopropanol precipitation, ethanolwash, and resuspension in aqueous solution; or lysis and denaturationfollowed by isolation on solid support, such as a Qiagen resin andreconstitution in aqueous solution; or lysis and denaturation innon-phenolic, aqueous solutions followed by enzymatic conversion of RNAto DNA template copies.

[0074] Normally, prior to applying the processes of the invention,steady state RNA expression levels for the genes, and sets of genes,disclosed herein will have been obtained. It is the steady state levelof such expression that is affected by potential anti-neoplastic agentsas determined herein. Such steady state levels of expression are easilydetermined by any methods that are sensitive, specific and accurate.Such methods include, but are in no way limited to, real timequantitative polymerase chain reaction (PCR), for example, using aPerkin-Elmer 7700 sequence detection system with gene specific primerprobe combinations as designed using any of several commerciallyavailable software packages, such as Primer Express software, solidsupport based hybridization array technology using appropriate internalcontrols for quantitation, including filter, bead, or microchip basedarrays, solid support based hybridization arrays using, for example,chemiluminescent, fluorescent, or electrochemical reaction baseddetection systems.

[0075] In one embodiment of the present invention, a set of genes usefulin evaluating, or screening, or otherwise assaying, one or more chemicalagents for anti-neoplastic activity in the assays disclosed herein willhave already been shown to have differences in the ratios of steadystate RNA levels in cancer cells, or tissues, relative to normal, ornon-tumorous cells or tissues, or will have exhibited differences in theexpression ratios in tumor samples compared to normal samples betweengenes in a given subset of the set of genes disclosed herein, or willhave gene expression that has increased from undetectable levels todetectable levels, or vice versa, as the case may be, especially wheresensitive detection methods are employed, or conversely will havedecreased from detectable levels to undetectable levels with suchprocedures, especially sensitive procedures.

[0076] The genes, and gene sequences, useful in practicing the methodsof the present invention are genes that are found to be selectivelyexpressed in, or not expressed in, cancer cells as compared tonon-cancer cells, or in which expression is down-regulated orup-regulated, as the case may be, in cancerous cells as compared tonon-cancerous cells. Thus, these may include genes, or sets of genes,expressed in cancer cells but absent from, or inactive in, non-cancerouscells, or may include genes, or sets of genes, expressed innon-cancerous cells, but not expressed in cancer cells. Alternatively,the genes useful in practicing the present invention may be moreexpressed, or less expressed, in a cancerous cell relative to anon-cancerous cell. Such genes are generally those comprising thesequences of SEQ ID NO: 1-318, with SEQ ID NO: 230-318 exhibitingelevated expression in cancer cells relative to normal cells and viceversa for SEQ ID NO: 1-229.

[0077] In accordance with the foregoing, the present invention furtherrelates to a process for determining the cancerous status of a testcell, comprising determining expression in said test cell of at leastone gene that corresponds to, or includes, one of the nucleotidesequences selected from the sequences of SEQ ID NO: 1-318, or anucleotide sequence that is at least 90%, preferably at least 95%,identical thereto, and then comparing said expression to expression ofsaid at least one gene in at least one cell known to be non-cancerouswhereby a difference in said expression indicates that said cell iscancerous.

[0078] In a particular embodiment, the present invention is directed toa process for determining the cancerous status of a cell to be tested,comprising determining the presence in said cell of at least one genethat includes one of the nucleotide sequences selected from thesequences of SEQ ID NO: 1-318, including sequences having substantialidentity homologous to said sequences, or characteristic fragmentsthereof, or the complements of any of the foregoing and then comparingthe pattern of said gene presence and/or absence with that found for acell known, or believed, to be non-cancerous, or normal, at least withrespect to its genetic complement.

[0079] With respect to genes that correspond to at least one of thesequences of SEQ ID NO: 230-318, up regulation of expression in cancercells (as compared to non-cancer cells, which may lack said genes, orsaid gene expression, altogether) is indicative of a cancerous, orpotentially cancerous, condition.

[0080] In specific embodiments, the present invention relates toembodiments wherein the genetic pattern is the modulation of expressionof more than one gene, preferably 3, 4, or 5 genes, and even includespatterns where there is a modulation of expression of as many as 10, ormore, genes. Thus, where a genetic pattern is the modulation ofexpression of 5 genes in a cancerous cell as compared to a non-cancerouscell from the same tissue type, such as a cancerous pancreas cell,versus a non-cancerous cell of pancreas, such a pattern indicates alikelihood that such genes (i.e., the modulation of expression of those5 genes) is an indicator of cancerous status and thereby provides ameans of diagnosing a cancerous, or potentially cancerous, status. Theabsence of a specific set of genes from cancerous cells where said genesare present in otherwise normal cells, especially those of a similartype, is also indicative of a correlation with the cancerous state andthus can likewise be used as a means of diagnosing the cancerous statein other cells suspected of being cancerous.

[0081] In a particular embodiment, the gene sequences as disclosedherein are indicative of the cancerous or normal state of pancreastissues. This further includes SEQ ID NO: 1-318 for pancreas, whereinSEQ ID NO: 1-229 represent genes or gene sequences expressed in normalpancreas but not in pancreas adenocarcinoma and wherein SEQ ID NO:230-318 represent genes or gene sequences expressed in pancreasadenocarcinoma but not in normal pancreas.

[0082] The gene patterns indicative of a cancerous state need not becharacteristic of every cell found to be cancerous. Thus, the methodsdisclosed herein are useful for detecting the presence of a cancerouscondition within a tissue where less than all cells exhibit the completepattern. For example, a set of selected genes, comprising sequenceshomologous under stringent conditions (i.e., at least 95% identical) toat least one of the sequences of SEQ ID NO: 230-318 and wherein thesignature set is comprised of genes expressed and/or up-regulated incancer cells relative to normal cells, as disclosed above for thesignature gene set (or sets) used for practicing the invention, may befound, using appropriate probes, either DNA or RNA, to be present in aslittle as 60% of cells derived from a sample of tumorous, or malignant,tissue while being absent from as much as 60% of cells derived fromcorresponding non-cancerous, or otherwise normal, tissue (and thus beingpresent in as much as 40% of such normal tissue cells). In a preferredembodiment, such gene pattern is found to be present in at least 70% ofcells drawn from a cancerous tissue and absent from at least 70% of acorresponding normal, non-cancerous, tissue sample. In an especiallypreferred embodiment, such gene pattern is found to be present in atleast 80% of cells drawn from a cancerous tissue and absent from atleast 80% of a corresponding normal, non-cancerous, tissue sample. In amost preferred embodiment, such gene pattern is found to be present inat least 90% of cells drawn from a cancerous tissue and absent from atleast 90% of a corresponding normal, non-cancerous, tissue sample. In anadditional embodiment, such gene pattern is found to be present in atleast 100% of cells drawn from a cancerous tissue and absent from atleast 100% of a corresponding normal, non-cancerous, tissue sample,although the latter embodiment may represent a rare occurrence.

[0083] Conversely, where the signature set (such as SEQ ID NO: 1-229) isexpressed or up-regulated in normal cells versus cancerous cells, asdisclosed herein, expression in the normal cells but not in suspectedcancerous cells may confirm a cancerous state in a suspected canceroussample where the cells would show lower than expected expression ofgenes corresponding to one of these sequences.

[0084] Although the presence or absence of expression of one or moreselected gene sequences may be indicative of a cancerous status for agiven cell, the mere presence or absence of such a gene pattern may notalone be sufficient to achieve a malignant condition and thus the levelof expression of such gene pattern may also be a significant factor indetermining the attainment of a cancerous state. While a pattern of geneexpression may be present in both cancerous and non-cancerous cells, therelative level of expression, as determined by any of the methodsdisclosed herein, all of which are well known in the art, may differbetween the cancerous versus the non-cancerous cells. Thus, it becomesessential to also determine the level of expression of one or more ofsaid genes as a separate means of diagnosing the presence of a cancerousstatus for a given cell, groups of cells, or tissues, either in cultureor in situ.

[0085] In accordance with the invention disclosed herein, adetermination of an anticancer agent using the signature gene sets forpancreas described herein is based on patterns of modulation of suchgenes so that increase or decrease in expression of a gene due to thepresence of such a potential agent may or may not be meaningful. Thus,the more genes in a gene set as disclosed herein that are affected bysaid agent the more likely said agent is an effective therapeutic agent.

[0086] In addition, different agents may have different abilities toaffect the genes of a signature gene set. For example, if a potentialtherapeutic agent, say, agent A, causes a gene or group of genes of acharacteristic or signature gene set, or even all of the genes of saidgene set, to exhibit decreased expression, such as where a lower amountof mRNA is expressed from said gene(s), or less protein is produced fromsaid mRNA, but a second potential agent, say, agent B, while modulatingthe activity of the same or related genes causes said expression to bereduced to half, such as where only half as much mRNA is transcribed oronly half as much protein is translated from said mRNA as for agent A,then agent B is considered to have twice as much therapeutic potentialas agent A.

[0087] Such modulation or change of activity as determined using theassays disclosed herein may include either an increase or a decrease inactivity of said genes or gene sequences. Thus, where a gene isexpressed in cancer cells but not in normal cells, or is up-regulated incancer cells relative to normal cells, of the same organ or tissue type,an agent that down-regulates said gene or genes, or gene sequences, orprevents their expression entirely, is considered a potential antitumoragent within the present disclosure. Conversely, where an agent causesexpression of a gene or genes, or gene sequences, expressed in normalcells but not in cancer cells, or where said agent up-regulates a geneor genes, or gene sequences, that are expressed in normal cells but notin cancer cells, or are up-regulated in normal cells but not in cancercells, of the same organ or tissue type, said agent is considered to bea potential antitumor agent within the present disclosure.

[0088] The present invention also relates to a process that comprises amethod for producing a product comprising identifying an agent accordingto one of the disclosed processes for identifying such an agent (such asthe therapeutic agents identified according to the assay proceduresdisclosed herein) wherein said product is the data collected withrespect to said agent as a result of said identification process, orassay, and wherein said data is sufficient to convey the chemicalcharacter and/or structure and/or properties of said agent. For example,the present invention specifically contemplates a situation whereby auser of an assay of the invention may use the assay to screen forcompounds having the desired enzyme modulating activity and, havingidentified the compound, then conveys that information (i.e.,information as to structure, dosage, etc) to another user who thenutilizes the information to reproduce the agent and administer it fortherapeutic or research purposes according to the invention. Forexample, the user of the assay (user 1) may screen a number of testcompounds without knowing the structure or identity of the compounds(such as where a number of code numbers are used the first user issimply given samples labeled with said code numbers) and, afterperforming the screening process, using one or more assay processes ofthe present invention, then imparts to a second user (user 2), verballyor in writing or some equivalent fashion, sufficient information toidentify the compounds having a particular modulating activity (forexample, the code number with the corresponding results). Thistransmission of information from user 1 to user 2 is specificallycontemplated by the present invention.

[0089] In accordance with the foregoing, the present invention furtherrelates to a process for determining the cancerous status of a cell tobe tested, comprising determining the level of expression in said cellof at least one gene that includes one of the nucleotide sequencesselected from the sequences of SEQ ID NO: 1 -318, including sequencessubstantially identical to said sequences, or characteristic fragmentsthereof, or the complements of any of the foregoing and then comparingsaid expression to that of a cell known to be non-cancerous whereby thedifference in said expression indicates that said cell to be tested iscancerous.

[0090] In specific embodiments of the present invention, said expressionis determined for more than one of said genes, such as 2, 3, 4, 5, ormore such genes, considered as a set, and even as many as a set of 10such genes. A set of genes, for example, 5 such genes, may be found tobe expressed at certain levels in cancer cells but are found to beexpressed at lower levels (or not expressed at all) in non-cancerous, ornormal, cells. Conversely, a set of, for example, 5 such genes may befound to be expressed in normal (i.e., non-cancerous) cells butexpressed at lower levels (or not expressed at all) in cancer cells.Thus, by determining the set or pattern of genes expressed in cancercells but expressed at lower levels (or not at all) in non-cancer, orvice versa, a method is achieved for diagnosing cancerous conditionswherein said genes are selected from those that include one of thesequences, or fragments of sequences, including complementary sequences,selected from SEQ ID NO: 1 -318. Using the methods disclosed herein,pancreas or other cancers can be readily detected using the methods ofthe present invention.

[0091] In accordance with the invention, although gene expression for agene that includes as a portion thereof one of the nucleotide sequencesof SEQ ID NO: 1-318, is preferably determined by use of a probe that isa fragment of such nucleotide sequence, it is to be understood that theprobe may be formed from a different portion of the gene. Thus, for eachgene of the signature set of the present invention, the nucleotidesequence disclosed with respect to a specific sequence ID number may beonly a portion of the nucleotide sequence that encodes expression of thegene. As a result, expression of the gene may be determined by use of anucleotide probe that hybridizes to messenger RNA (mRNA) transcribedfrom a portion of the gene other than the specific nucleotide sequencedisclosed with reference to a sequence ID number as recited herein.

[0092] The present invention further relates to a process fordetermining a cancer initiating, facilitating or suppressing genecomprising the steps of contacting a cell with a cancer modulating agentand determining a change in expression of a gene selected from the groupconsisting of the gene sequences of SEQ ID NO: 1-318 and therebyidentifying said gene as being a cancer initiating or facilitating gene.

[0093] Thus, some or all of the genes within the signature gene setsdisclosed herein as SEQ ID NO: 1-318 are found to play a direct role inthe initiation or progression of cancer or even other diseases anddisease processes. Because changes in expression of these genes (eitherup-regulation or down-regulation) are linked to the disease state (i.e.cancer), the change in expression may contribute to the initiation orprogression of the disease. For example, if a gene that is up-regulatedis an oncogene, or if a gene that is down-regulated is a tumorsuppressor, such a gene provides for a means of screening for smallmolecule therapeutics beyond screens based upon expression output alone.For example, genes that display up-regulation in cancer and whoseelevated expression contributes to initiation or progression of diseaserepresent targets in screens for small molecules that inhibit or blocktheir function. Examples include, but are not be limited to, kinaseinhibition, cellular proliferation, substrate analogs that block theactive site of protein targets, etc. Similarly, genes that displaydown-regulation in cancer and whose absence results in initiation orprogression of disease are valuable therapeutics for gene therapy.

[0094] In accordance therewith, the present invention relates to aprocess for determining a cancer initiating or facilitating genecomprising contacting a cell expressing a test gene (one whose status asa cancer initiating or facilitating gene is to be determined) with anagent that decreases the expression of a gene corresponding to apolynucleotide having a sequence selected from the group consisting ofSEQ ID NO: 230-318, and detecting a decrease in expression of said testgene compared to when said agent is not present, thereby identifyingsaid test gene as being a cancer initiating or facilitating gene. Suchgenes may, of course, be oncogenes and said decrease in expression maybe due to a decrease in copy number of said gene in said cell or a cellderived from said cell, such as where copy number is reduced followingcellular replication.

[0095] The present invention also relates to a process for determining acancer suppressor gene comprising contacting a cell expressing a testgene (one whose status as a cancer suppressor gene is to be determined)with an agent that increases the expression of a gene that encodes anRNA at least 95% identical to an RNA encoded by (i.e., corresponds to) apolynucleotide having a sequence selected from the group consisting ofSEQ ID NO: 1-229 and detecting an increase in expression of said testgene compared to when said agent is not present, thereby identifyingsaid test gene as being a cancer suppressor gene. The sequence identitymay include identical sequences, as defined herein, and such a processincludes embodiments wherein the increase in expression is due to anincrease in copy number of the gene in said cell or a cell derived fromsaid cell, such as by cellular replication. Such increase in expressionmay also include the induction of expression in a cell, especially acancer cell, such as a pancreas cancer cell, where such expression isnot detectable in the absence of the agent.

[0096] It should be noted that there are a variety of different contextsin which genes have been evaluated as being involved in the cancerousprocess. Thus, some genes may be oncogenes and encode proteins that aredirectly involved in the cancerous process and thereby promote theoccurrence of cancer in an animal. In addition, other genes may serve tosuppress the cancerous state in a given cell or cell type and therebywork against a cancerous condition forming in an animal. Other genes maysimply be involved either directly or indirectly in the cancerousprocess or condition and may serve in an ancillary capacity with respectto the cancerous state. All such types of genes are deemed with those tobe determined in accordance with the invention as disclosed herein.Thus, the gene determined by said process of the invention may be anoncogene, or the gene determined by said process may be a cancerfacilitating gene, the latter including a gene that directly orindirectly affects the cancerous process, either in the promotion of acancerous condition or in facilitating the progress of cancerous growthor otherwise modulating the growth of cancer cells, either in vivo or exvivo. In addition, the gene determined by said process may be a cancersuppressor gene, which gene works either directly or indirectly tosuppress the initiation or progress of a cancerous condition. Such genesmay work indirectly where their expression alters the activity of someother gene or gene expression product that is itself directly involvedin initiating or facilitating the progress of a cancerous condition. Forexample, a gene that encodes a polypeptide, either wild or mutant intype, which polypeptide acts to suppress of tumor suppressor gene, orits expression product, will thereby act indirectly to promote tumorgrowth.

[0097] In accordance with the foregoing, the process of the presentinvention includes cancer modulating agents that are themselves eitherpolypeptides, or small chemical entities, that affect the cancerousprocess, including initiation, suppression or facilitation of tumorgrowth, either in vivo or ex vivo. Said cancer modulating agent may havethe effect of increasing gene expression or said cancer modulating agentmay have the effect of decreasing gene expression as such terms havebeen described herein.

[0098] In keeping with the present disclosure, the present inventionalso relates to a process for treating cancer comprising contacting acancerous cell with an agent having activity against an expressionproduct encoded by a gene sequence selected from the group consisting ofSEQ ID NO: 1-318. More specifically, the present invention relates to aprocess for treating cancer comprising contacting a cancerous cell withan agent having activity against an expression product encoded by a genesequence selected from the group consisting of SEQ ID NO: 230-318. Sucha process includes an embodiment wherein the cancerous cell is contactedin vivo. Such treatment includes treatment of a patient, such as a humanbeing. The agent may include an antibody that reacts with a polypeptideencoded by such a gene.

[0099] Thus, some or all of the genes within these signature gene setsrepresent individual targets for therapeutic intervention, based atleast in part on their pattern(s) of expression. For example, geneswithin the signature gene sets that encode cell surface molecules andare up-regulated in cancer as compared to normal cells. The proteinsencoded by such genes, due to their elevated expression in cancer cells,represent highly useful therapeutic targets for “targeted therapies”utilizing such affinity structures as, for example, antibodies coupledto some cytotoxic agent. In such methodology, it is advantageous thatnothing need be known about the endogenous ligands or binding partnersfor such cell surface molecules. Rather, an antibody or equivalentmolecule that can specifically recognize the cell surface molecule(which could include an artificial peptide, a surrogate ligand, and thelike) that is coupled to some agent that can induce cell death or ablock in cell cycling offers therapeutic promise against these proteins.Thus, such approaches include the use of so-called suicide “bullets”against intracellular proteins.

[0100] The process of the present invention includes embodiments of theabove-recited process wherein said cancer cell is contacted in vivo aswell as ex vivo, preferably wherein said agent comprises a portion, oris part of an overall molecular structure, having affinity for saidexpression product. In one such embodiment, said portion having affinityfor said expression product is an antibody, especially where saidexpression product is a polypeptide or oligopeptide or comprises anoligopeptide portion, or comprises a polypeptide.

[0101] Such an agent can therefore be a single molecular structure,comprising both affinity portion and anti-cancer activity portions,wherein said portions are derived from separate molecules, or molecularstructures, possessing such activity when separated and wherein suchagent has been formed by combining said portions into one largermolecular structure, such as where said portions are combined into theform of an adduct. Said anti-cancer and affinity portions may be joinedcovalently, such as in the form of a single polypeptide, orpolypeptide-like, structure or may be joined non-covalently, such as byhydrophobic or electrostatic interactions, such structures having beenformed by means well known in the chemical arts. Alternatively, theanti-cancer and affinity portions may be formed from separate domains ofa single molecule that exhibits, as part of the same chemical structure,more than one activity wherein one of the activities is against cancercells, or tumor formation or growth, and the other activity is affinityfor an expression product produced by expression of genes related to thecancerous process or condition.

[0102] In one embodiment of the present invention, a chemical agent,such as a protein or other polypeptide, is joined to an agent, such asan antibody, having affinity for an expression product of a cancerouscell, such as a polypeptide or protein encoded by a gene related to thecancerous process, especially a gene sequence corresponding to oneselected from the group consisting of the sequences of SEQ ID NO:230-318. In a specific embodiment, said expression product is a cellsurface receptor, such as a protein or glycoprotein or lipoprotein,present on the surface of a cancer cell, such as where it is part of theplasma membrane of said cancer cell, and acts as a therapeutic targetfor the affinity portion of said anticancer agent and where, afterbinding of the affinity portion of such agent to the expression product,the anti-cancer portion of said agent acts against said expressionproduct so as to neutralize its effects in initiating, facilitating orpromoting tumor formation and/or growth. In a separate embodiment of thepresent invention, binding of the agent to said expression product may,without more, have the effect of deterring cancer promotion,facilitation or growth, especially where the presence of said expressionproduct is related, either intimately or only in an ancillary manner, tothe development and growth of a tumor. Thus, where the presence of saidexpression product is essential to tumor initiation and/or growth,binding of said agent to said expression product will have the effect ofnegating said tumor promoting activity.

[0103] In one such embodiment, said agent is an apoptosis-inducing agentthat induces cell suicide, thereby killing the cancer cell and haltingtumor growth. In alternative embodiments of the foregoing, the presentinvention relates to a process for treating a cancerous condition in ananimal afflicted therewith comprising administering to said animal atherapeutically effective amount of an agent first identified as havinganti-neoplastic activity using an assay process as disclosed hereinaccording to the present invention, such as a cancer-related genemodulator as identified according to the processes of the invention.Such processes also include the ability to protect against developmentof a cancerous state by using agents identified by the assay processesof the invention. Thus, the present invention specifically contemplatesa process for protecting an animal against cancer comprisingadministering to an animal at risk of developing cancer atherapeutically effective amount of an agent first identified as havinganti-neoplastic activity using one or more of the assay processesdisclosed herein for identifying such agents.

[0104] The processes of the present invention take advantage of thecorrelation of changes in mRNA expression profiles of these signaturegene sets with potential (depending on the form of cancer) changes inDNA copy number of the chromosomal regions wherein these genes arelocated. Of course, the precise nature of the change in mRNA expression(e.g. a signature set of genes that are up-regulated at thetranscriptional level) may also indicate a change in the DNA copy numberfor the genomic regions in which these genes are located (e.g. anamplification of the genomic DNA region that contains the involved geneor genes).

[0105] Many cancers contain chromosomal rearrangements, which typicallyrepresent translocations, amplifications, or deletions of specificregions of genomic DNA. A recurrent chromosomal rearrangement that isassociated with a specific stage and type of cancer always affects agene (or possibly genes) that play a direct and critical role in theinitiation or progression of the disease. Many of the known oncogenes ortumor suppressor genes that play direct roles in cancer have either beeninitially identified based upon their positional cloning from arecurrent chromosomal rearrangement or have been demonstrated to fallwithin a rearrangement subsequent to their cloning by other methods. Inall cases, such genes display amplification at both the level of DNAcopy number and at the level of transcriptional expression at the mRNAlevel.

[0106] At least some of the genes that are contained within signaturegene sets disclosed herein (SEQ ID NO: 230-318) display changes in theirmRNA expression profiles (depending on the precise reading frameinvolved) within cancer samples due, in part, to changes in their DNAcopy number as a result of specific chromosomal rearrangements in thosecancer cells. The utilities that follow from this are (i) that the genescontained within these signature gene sets offer a time saving shortcutto the identification of novel chromosomal rearrangements,amplifications, or deletions that are associated with cancer, and/or(ii) represent key genes affected by such chromosomal rearrangements,amplifications, or deletions and, therefore, play a key role in theinitiation or progression of the disease. Genes within the signaturesets that identify changes in the DNA copy number (based upon theirchanges in expression at the mRNA level) afford an entry point intoother forms of diagnostic assay for the initiation, staging, orprogression of cancer to be conducted in tissue samples at the DNA level(e.g. if gene X identifies a novel chromosomal amplification associatedwith cancer, then that specific chromosomal region defined by gene Xwould serve as the basis for a diagnostic assay for cancer, wheregenomic DNA is extracted from tissue samples and evaluated for thepresence of the specific amplification), and also the rapid positionalcloning of genes that play vital and direct roles in the initiation orprogression of cancer.

[0107] In one embodiment of the present invention, said change inexpression may be determined by determining a change in gene copynumber, wherein said change in copy number is an increase in copy numberor wherein said change in copy number is a decrease in copy number. Forexample, copy number of a sequence expressed, or over-expressed, in acancerous cell may be decreased due to the presence of ananti-neoplastic agent as identified according to the assays proceduresof the present invention.

[0108] A change in gene copy number may be determined by determining achange in expression of messenger RNA encoded by a particular genesequence, especially where said sequence is one selected from the groupconsisting of the sequences of SEQ ID NO: 1-318, especially SEQ ID NO:230-318 (the latter being expressed in cancer cells but not expressed atdetectable levels in normal cells) and 1-229 (the latter being expressedin normal cells but not at detectable levels in cancer cells). Also inaccordance with the present invention, said gene may be a cancerinitiating gene, a cancer facilitating gene, or a cancer suppressinggene. In carrying out the methods of the present invention, a cancerfacilitating gene is a gene that, while not directly initiating orsuppressing tumor formation or growth, said gene acts, such as throughthe actions of its expression product, to direct, enhance, or otherwisefacilitate the progress of the cancerous condition, including where suchgene acts against genes, or gene expression products, that wouldotherwise have the effect of decreasing tumor formation and/or growth.

[0109] The present invention also relates to a process for treatingcancer comprising inserting into a cancerous cell a gene constructcomprising an anti-cancer gene operably linked to a promoter or enhancerelement such that expression of said anti-cancer gene causes suppressionof said cancer and wherein said promoter or enhancer element is apromoter or enhancer element modulating a gene, or genes, correspondingto a sequence, or sequences, selected from the group consisting of thesequences of SEQ ID NO: 1-229.

[0110] The signature sets or signature gene sets disclosed herein areuseful in identifying genetic regulatory elements within the promotersof the genes contained within the signature sets that are specific tonormal tissue and/or the corresponding cancer. Each signature set is acollection of genes that share a gross common pattern of transcriptionalregulation in cancer vs. normal (e.g. a signature set of genes that aretranscriptionally up-regulated in cancer).

[0111] In one such embodiment, analyzing and comparing the DNA sequencesof the promoter regions of all the genes contained within the signatureset serves to identify conserved stretches or motifs of sequences withinsubsets of genes that represent cis-acting elements that specificallydrive a form of gene expression (e.g. increased transcriptionalexpression in cancer). The identification of such cis-acting regulatoryelements is then available for use in driving the cancer-specificexpression of suicide genes or toxins via genetic therapy usingtechnology already well known in the art.

[0112] In separate embodiments, said anti-cancer gene is a cancersuppressor gene or encodes a polypeptide having anticancer activity,especially where said polypeptide has apoptotic activity.

[0113] In additional embodiments, such insertion of the gene constructinto a cancerous cell is accomplished in vivo, for example using a viralor plasmid vector. Such methods can also be applied to in vitro uses.The methods of the present invention are readily applicable to differentforms of gene therapy, either where cells are genetically modified exvivo and then administered to a host or where the gene modification isconducted in vivo using any of a number of suitable methods involvingvectors especially suitable to such therapies, such as the use ofspecial viral vectors, including adeno-associated viruses andadenoviruses, as well as retroviruses and specially constructed plasmidsto accomplish such therapies. The use of these and other vectors is wellknown to those skilled in the art and need not be described further.

[0114] The present method also relates to a process for determiningfunctionally related genes comprising contacting one or more genesequences selected from the group consisting of the sequences of SEQ IDNO: 1-318 with an agent that modulates expression of more than one genein such group and thereby determining a subset of genes of said group.

[0115] In accordance with the present invention, said functionallyrelated genes are genes modulating the same metabolic pathway or saidgenes are genes encoding functionally related polypeptides. In one suchembodiment, said genes are genes whose expression is modulated by thesame transcriptional activator or enhancer sequence, especially wheresaid transcriptional activator or enhancer increases, or otherwisemodulates, the activity of a gene sequence selected from the groupconsisting of SEQ ID NO: 1-318. In specific embodiments, the sequencesmay be SEQ ID NO: 230-318 or may be SEQ ID NO: 1-229, or subsets ofthese.

[0116] In one such embodiment, small molecule screens serve to identifychanges in expression of genes within a signature set and therebyprovide a tool for the identification of specific functional pathwaysand a means of assigning defined functions to novel genes.

[0117] In situations where a signature set of genes that aretranscriptionally up-regulated in cancer cells compared to normal cells,such screens facilitate the identification of small molecules thatdown-regulate the expression of the genes of the signature set withincancer cells. While such therapeutics make a cancer cell “look” morenormal, based upon the expression of the genes within the signature set,what actually happens when such screens are put into practice is thatall genes within the signature sets do not respond identically to eachsmall molecule within a chemical compound library. If an averagesignature set contains 200 different genes, for example, and theexpression of all 200 genes is monitored in response to a library ofsome 50,000 chemical compounds, and subsets of genes within thesignature set consistently change their patterns of expression inresponse to particular chemicals (e.g., 10 of the genes always changeexpression in a coordinated way, such as down-regulation of one genewithin the group of 10) then it always causes the down-regulation of theother 9 specific genes as well.

[0118] Such subsets or subgroups of genes within each signature set thatchange their expression in a coordinated way in response to chemicalcompounds represent genes that are located within a common metabolic,signaling, physiological, or functional pathway so that by analyzing andidentifying such subsets one can (a) assign known genes and novel genesto specific pathways and (b) identify specific functions and functionalroles for novel genes that are grouped into pathways with genes forwhich their functions are already characterized or described. Forexample, one might identify a subgroup of 10 genes within a signatureset (5 known genes and 5 novel genes) that change expression in acoordinated fashion and for which the 5 known genes are involved inapoptosis thereby implicating the other 5 novel genes as playing a rolein apoptotic cellular processes. Therefore, the processes disclosedaccording to the present invention at once provide a novel means ofassigning function to genes, i.e. a novel method of functional genomics,and a means for identifying chemical compounds that have potentialtherapeutic effects on specific cellular pathways. Such chemicalcompounds may have therapeutic relevance to a variety of diseasesoutside of cancer as well, in cases where such diseases are known or aredemonstrated to involve the specific cellular pathway that is affected.

[0119] It should be cautioned that, in carrying out the procedures ofthe present invention as disclosed herein, any reference to particularbuffers, media, reagents, cells, culture conditions and the like are notintended to be limiting, but are to be read so as to include all relatedmaterials that one of ordinary skill in the art would recognize as beingof interest or value in the particular context in which that discussionis presented. For example, it is often possible to substitute one buffersystem or culture medium for another and still achieve similar, if notidentical, results. Those of skill in the art will have sufficientknowledge of such systems and methodologies so as to be able, withoutundue experimentation, to make substitutions that will optimally servetheir purposes in using the methods and procedures disclosed herein.

[0120] The present invention will now be further described by way of thefollowing non-limiting example but it should be kept clearly in mindthat other and different embodiments of the methods disclosed accordingto the present invention will no doubt suggest themselves to those ofskill in the relevant art.

EXAMPLE

[0121] SW480 cells (or other sells of choice, cancerous or normal, suchas pancreas cancer cells or cell lines) are grown to a density of 226cells/cm² in Leibovitz's L-15 medium supplemented with 2 mM L-glutamine(90%) and 10% fetal bovine serum. The cells are collected aftertreatment with 0.25% trypsin, 0.02% EDTA at 37° C. for 2 to 5 minutes.The trypsinized cells are then diluted with 30 ml growth medium andplated at a density of 50,000 cells per well in a 96 well plate (200μl/well). The following day, cells are treated with either compoundbuffer alone, or compound buffer containing a chemical agent to betested, for 24 hours. The media is then removed, the cells lysed and theRNA recovered using the RNAeasy reagents and protocol obtained fromQiagen. RNA is quantitated and 10 ng of sample in 1 μl are added to 24μl of Taqman reaction mix containing 1× PCR buffer, RNAsin, reversetranscriptase, nucleoside triphosphates, amplitaq gold, tween 20,glycerol, bovine serum albumin (BSA) and specific PCR primers and probesfor a reference gene (18S RNA) and a test gene (Gene X). Reversetranscription is then carried out at 48° C. for 30 minutes. The sampleis then applied to a Perkin Elmer 7700 sequence detector and heatdenatured for minutes at 95° C. Amplification is performed through 40cycles using 15 seconds annealing at 60° C. followed by a 60 secondextension at 72° C. and 30 second denaturation at 95° C. Data files arethen captured and the data analyzed with the appropriate baselinewindows and thresholds.

[0122] The quantitative difference between the target and referencegenes is then calculated and a relative expression value determined forall of the samples used. This procedure is then repeated for each of thetarget genes in a given signature, or characteristic, set and therelative expression ratios for each pair of genes is determined (i.e., aratio of expression is determined for each target gene versus each ofthe other genes for which expression is measured, where each gene'sabsolute expression is determined relative to the reference gene foreach compound, or chemical agent, to be screened). The samples are thenscored and ranked according to the degree of alteration of theexpression profile in the treated samples relative to the control. Theoverall expression of the set of genes relative to the controls, asmodulated by one chemical agent relative to another, is alsoascertained. Chemical agents having the most effect on a given gene, orset of genes, are considered the most anti-neoplastic.

[0123] In carrying out the methods of the invention, it is to beexpected that not all cells of a given sample of suspected cancerouscells will express all, or even most, of these genes but that asubstantial expression thereof in a substantial number of such cells issufficient to warrant a determination of a cancerous, or potentiallycancerous, condition. The sequences disclosed herein are represented bySEQ ID NO: 1 to 318 although different genes more or less relevant todifferent organs and tissues and some may be up-regulated in cancer andnot normal cells while others are up-regulated in normal cells but notcancerous cells. The sequences presented herein may be genomic,synthetic or cDNA sequences and may also be represented as RNAsequences. The sequences of the sequence listing herein are mostly cDNAsequences but can be used to locate genomic sequences.

1 318 1 291 DNA Homo sapiens 1 ggccgggcgc ggtggctcac gcctgtaatcccagcacttt gggaggccga ggcgggtgga 60 tcacctgagg tcaggagttc gagaccagcctggccaacat ggtgaaaccc cgtctctact 120 aaaaatacaa aaattagccg ggcgtggtggcgggcgcctg taatcccagc tactcgggag 180 gctgaggcag gagaatcgct tgaacccgggaggcggaggt tgcagtgagc cgagatcgcg 240 ccactgcact ccagcctggg caacaagagcgaaactccgt ctcaaaaaaa a 291 2 1761 DNA Homo sapiens 2 ttgccgatccgccgcccgtc cacacccgcc gccagctcac catggatgat gatatcgccg 60 cgctcgtcgtcgacaacggc tccggcatgt gcaaggccgg cttcgcgggc gacgatgccc 120 cccgggccgtcttcccctcc atcgtggggc gccccaggca ccagggcgtg atggtgggca 180 tgggtcagaaggattcctat gtgggcgacg aggcccagag caagagaggc atcctcaccc 240 tgaagtaccccatcgagcac ggcatcgtca ccaactggga cgacatggag aaaatctggc 300 accacaccttctacaatgag ctgcgtgtgg ctcccgagga gcaccccgtg ctgctgaccg 360 aggcccccctgaaccccaag gccaaccgcg agaagatgac ccagatcatg tttgagacct 420 tcaacaccccagccatgtac gttgctatcc aggctgtgct atccctgtac gcctctggcc 480 gtaccactggcatcgtgatg gactccggtg acggggtcac ccacactgtg cccatctacg 540 aggggtatgccctcccccat gccatcctgc gtctggacct ggctggccgg gacctgactg 600 actacctcatgaagatcctc accgagcgcg gctacagctt caccaccacg gccgagcggg 660 aaatcgtgcgtgacattaag gagaagctgt gctacgtcgc cctggacttc gagcaagaga 720 tggccacggctgcttccagc tcctccctgg agaagagcta cgagctgcct gacggccagg 780 tcatcaccattggcaatgag cggttccgct gccctgaggc actcttccag ccttccttcc 840 tgggcatggagtcctgtggc atccacgaaa ctaccttcaa ctccatcatg aagtgtgacg 900 tggacatccgcaaagacctg tacgccaaca cagtgctgtc tggcggcacc accatgtacc 960 ctggcattgccgacaggatg cagaaggaga tcactgccct ggcacccagc acaatgaaga 1020 tcaagatcattgctcctcct gagcgcaagt actccgtgtg gatcggcggc tccatcctgg 1080 cctcgctgtccaccttccag cagatgtgga tcagcaagca ggagtatgac gagtccggcc 1140 cctccatcgtccaccgcaaa tgcttctagg cggactatga cttagttgcg ttacaccctt 1200 tcttgacaaaacctaacttg cgcagaaaac aagatgagat tggcatggct ttatttgttt 1260 tttttgttttgttttggttt tttttttttt tttggcttga ctcaggattt aaaaactgga 1320 acggtgaaggtgacagcagt cggttggagc gagcatcccc caaagttcac aatgtggccg 1380 aggactttgattgcacattg ttgttttttt aatagtcatt ccaaatatga gatgcattgt 1440 tacaggaagtcccttgccat cctaaaagcc accccacttc tctctaagga gaatggccca 1500 gtcctctcccaagtccacac aggggaggtg atagcattgc tttcgtgtaa attatgtaat 1560 gcaaaatttttttaatcttc gccttaatac ttttttattt tgttttattt tgaatgatga 1620 gccttcgtgcccccccttcc ccctttttgt cccccaactt gagatgtatg aaggcttttg 1680 gtctccctgggagtgggtgg aggcagccag ggcttacctg tacactgact tgagaccagt 1740 tgaataaaagtgcacacctt a 1761 3 326 DNA Homo sapiens 3 gcgcacccgg ttcagctcgcctttcttggc cagagggccc ggttggactc acgggcgggg 60 catgatggtg gtgggtacgggcacctcgct ggcgctctcc tccctcctgt ccctgctgct 120 ctttgctggg atgcagatgtacagccgtca gctggcctcc accgagtggc tcaccatcca 180 gggcggcctg cttggttcgggtctcttcgt gttctcgctc actgccttca ataatctgga 240 gaatcttgtc tttggcaaaggattccaagc aaagatcttc cctgagattc tcctgtgcct 300 cctgttggct ctctttgcatctggcc 326 4 370 DNA Homo sapiens 4 caaagaaatt agcttttatt tgagactacttttccccaca tgtatctttt aagaattcta 60 tgctatgtga taacctgctt atccactgtcccaataccaa aatttctaac agcgaattat 120 acaactgctc taggtaataa ataagggttgtccttcactg attaagggaa taaacttcaa 180 taaacttaac aacaacaaaa aaaatcacactttagttttt aagttttaac agatgtattt 240 caaatacagc atgttttaca ggagttcacaagcttttcat ctctaaaaaa aaactttcaa 300 ctacctgact gttccattcc accccagacaaacctgacat gactgaacta cttcatgtgt 360 tactttccca 370 5 299 DNA Homosapiens 5 tggaggaaag ggacaggcct gggatatggc catcctggat tggcttcatcagaggaggct 60 gaaggcggac tgaggggccc cagtgttgga gcctcaggaa gaaccagcaaaagacagtcc 120 aacgagactt atcgagatgc tgttcgaaga gtcatgtttg ctcgatataaagaactcgat 180 taagaaagga gacaagttcc atgggataca acctccctct tgttttgtttgtctctcctt 240 ttcttttgtt actgttcttg ctgctagaac ttttttaaat aaactttttttcaatgtga 299 6 1361 DNA Homo sapiens 6 cattcgggga cgctctcagc tctcgactcactgcccagct tccttcaaaa tgtcaactga 60 tctcgaaatc ctgtgcaagc tcagcttggagggtgctcac tctacaccct caggtgcata 120 tgggtcagtc aaagcctaca ccaactttgatgctgagggg gatgctttga acattgaaag 180 gaccatcagg acaaaaggtg tgggtaagttcaccattgtc aacattttga ccaacagcag 240 gaatgctcgg agagaggatg ttgcctttgcctagcagaga aggaccacaa aggaacttac 300 atcagcactg aagtcagcct tactggccacctggagacag tcattttggg cctattgaag 360 acacctgctc agtatgatgc ttctgagctaaaagcttcca tgaaggggct gggaactgag 420 gaggactccc tcgttgagat catctgctcaacaaccaacc aggagctcca ggaaattaac 480 agagtctaca aagaaatgta caaaactgatctggagaagg acattatttc ggacacatat 540 ggtgacttct gcaagctgat gtttgccctggcaaatgtta gaagaccaga ggatggctct 600 gtcgttgatt atgaactgat tgaccaagatgcccgggatt tctgtgatgc tggagtgaag 660 aggaaaagaa ctgatgttcc caagtggatcagcatgatga ccgagtagag catgtcccac 720 ctccagaaag tatttgatag gtacaagagctacagccctt atgacatgtt ggaaagcatc 780 aagaaagagg ttaaaggaga cctggaaaatgctttcctga acctggtcca gtgcattcag 840 aacaagcccc tgtattttgc tgattggctgtactactcca tgaagggcca gggggctcga 900 gataaggtcc tgatcagaat catcgtctcccgcagtgaag tggacatgtt gaaaattagg 960 tctgaattca agagaaagta tggcatgtccctgtactact atatccagca agacactaag 1020 aacgactacc agaaagcact gctgtacctgtgtggtggag atgactgaag cccaacatag 1080 cttgagcttc cagaaacggt gctccccacgcttccagcta acaggtctag aaaaccagct 1140 tgtggctaac agtccctgtg gccgtccctgtgaagatgac attagcattg cccccaacct 1200 cattttagtt gcgtaagcat agcctggctttcctgtctag tctctcctgt aagccaaaga 1260 aatgtacatt ccaagcagtt ggaagtgaaatctatgatgt gaaacacttt gcctcctgtg 1320 tactgtgtca taaacagatg aataaactgaatttgtactt t 1361 7 340 DNA Homo sapiens misc_feature n=a,t,g or c 7gtgaactcct ggcctcaagg gatcctctgg catgccttgn ctcccaaagg cntaggatca 60caggcaaaag caccgtgtgt ttatttttcc cattcccttc ctttatctgc aatgcttttt 120tctttaaggc agcctaattt acaagcttgg ccttgaatta aaagagaacc cagaacccgc 180tcttggagtt tacgttctca aaccaacatc agagcaactg tctatcccca tataaataaa 240gttatctacc cctgctccta actgggtaca agttatgact acaactcagt gattttttaa 300attagtgtgc ctatttggtg aaatctgtga acttaatcaa 340 8 571 DNA Homo sapiens 8gttccatttc tatgggtttg gacaccgatg tagattatga aactgcattt attcattacc 60gtctggcttc tgagcagcaa cacagtgcac aagctatgtt taatctggga tatatgcatg 120agaaaggact gggcattaaa caggatattc accttgcgaa acgtttttat gacatggcag 180ctgtaagcca gcccagatgc acaagttcca gtcttcctag ccctctgcaa attgggcatc 240gtctatttct tgcagtacat acgggaaaca aacattcgag atatgttctc ccaacttgat 300atggaccagc ttttgggacc tgagtgggac ctttacctca tgaccatcat tgcgctctgt 360tgggaagtca tagcttacag gcaaaggcag caccaagaca tgcctgcacc caggcctcca 420gggccacggc cagctccacc ccagcaggag gggccaccag agcagcagcc accacagtaa 480taggcactgg gtccagcctt gatcagtgac agcgaaggaa gttatctgct gggaacactt 540gcatttgatt taggaccttg gggatccgat g 571 9 473 DNA Homo sapiens 9gctttcggtg gttccttggt gactgggaat tgcttgtgtg catgtgttgg gtgcatgctt 60ccgggtctca gctgccccag gcccgcacag gcaacccctt cccatccaaa gccattggtg 120gagcttctct ggaatcattt gccaaaagcc caaggcagaa tccaagggtc caagaccatt 180tccatggagc tcatgttttt cttttctgta ggaacttttt tttaaccagc acccaccata 240attccgaagc cacgtttcat ctttcctgga tcactacagt gaagtattac acgttgtaca 300cgttcccagt ctggccttgg cttgctcgga taaaactttg tatgtatttt gtatggcata 360gattctatat tgtaatgatg tcctatgcaa aaagagaaat taacgaaatt gtaaatttta 420ttgttttaac gtgtatgcat gtttagtgac gtttacattt tgaaataaaa ttt 473 10 255DNA Homo sapiens 10 ggggaaaagc cctatgaatg taacacatgc aggaaaaccttctctcaaaa gtcaaatctc 60 attgtacatc agagaacaca cataggagaa aaaccttatgaatgaattgg atattagaaa 120 tttccagcca caagtcagcc tccataatgc ctcagagtcttcacactgtg gagaagggcc 180 tgatgacatc ctgaatgttc aataactatc cacaaactcgccttatgtta ctccaaagta 240 acagtagggg ataaa 255 11 1559 DNA Homo sapiens11 gcggagcaca gtccgccgag cacaagctcc agcatcccgt caggggttgc aggtgtgtgg 60gaggcttgaa actgttacaa tatggctttc cttggactct tctctttgct ggttctgcaa 120agtatggcta caggggccac tttccctgag gaagccattg ctgacttgtc agtgaatatg 180tataatcgtc ttagagccac tggtgaagat gaaaatattc tcttctctcc attgagtatt 240gctcttgcaa tgggaatgat ggaacttggg gcccaaggat ctacccagaa agaaatccgc 300cactcaatgg gatatgacag cctaaaaaat ggtgaagaat tttctttctt gaaggagttt 360tcaaacatgg taactgctaa agagagccaa tatgtgatga aaattgccaa ttccttgttt 420gtgcaaaatg gatttcatgt caatgaggag tttttgcaaa tgatgaaaaa atattttaat 480gcagcagtaa atcatgtgga cttcagtcaa aatgtagccg tggccaacta catcaataag 540tgggtggaga ataacacaaa caatctggtg aaagatttgg tatccccaag ggattttgat 600gctgccactt atctggccct cattaatgct gtctatttca aggggaactg gaagtcgcag 660tttaggcctg aaaatactag aaccttttct ttcactaaag atgatgaaag tgaagtccaa 720attccaatga tgtatcagca aggagaattt tattatgggg aatttagtga tggctccaat 780gaagctggtg gtatctacca agtcctagaa ataccatatg aaggagatga aataagcatg 840atgctggtgc tgtccagaca ggaagttcct cttgctactc tggagccatt agtcaaagca 900cagctggttg aagaatgggc aaactctgtg aagaagcaaa aagtagaagt atacctgccc 960aggttcacag tggaacagga aattgattta aaagatgttt tgaaggctct tggaataact 1020gaaattttca tcaaagatgc aaatttgaca ggcctctctg ataataagga gatttttctt 1080tccaaagcaa ttcacaagtc cttcctagag gttaatgaag aaggctcaga agctgctgct 1140gtctcaggaa tgattgcaat tagtaggatg gctgtgctgt atcctcaagt tattgtcgac 1200catccatttt tctttcttat cagaaacagg agaactggta caattctatt catgggacga 1260gtcatgcatc ctgaaacaat gaacacaagt ggacatgatt tcgaagaact ttaagttact 1320ttatttgaat aacaaggaaa acagtaacta agcacattat gtttgcaact ggtatatatt 1380taggatttgt gttttacagt atatcttaag ataatattta aaatagttcc agataaaaac 1440aatatatgta aattataagt aacttgtcaa ggaatgttat cagtattaag ctaatggtcc 1500tgttatgtca ttgtgtttgt gtgctgttgt ttaaaataaa agtacctatt gaacatgtg 1559 12397 DNA Homo sapiens 12 tttttttttt ttttaagatg taagaaaata tatttattttttccatgaca atactatgat 60 aaaattgtta aatacatgca tgttttaaaa acagacataagtaacatctt tagagttaac 120 agccaagcat actagtttta catttatggt gttttagtaatagattattt tctatgtttt 180 tgctataatc atgttttcca aaagatacag aaactaaattctgaaattat acaatgatat 240 aaagtgtcca aatttcccat tctaacagca atttaaaatccaaattttca caaggcagga 300 aatgcttcag ttatcatcta agtggagttg ttttattccatattactctc cagaattctg 360 tgaatcagac tggaatcaca ccccatggga cttcatc 39713 445 DNA Homo sapiens 13 tttttttaac agcagataga ttctttatgt tcaagacagcaaattcagat acaaaaaccc 60 accgccatcg tccctccctc cctcctgctc tgggccagggatgggcctgg aaggagagat 120 gggaggtggg gaggaggttg cggggttcac agcagactcgtgtcaaatgc ggaggtaaca 180 ggctccacag ggagggggct cctctcagga ggggtgagggcattattgca tttgctgggg 240 ggaaggacaa ccctctcccc tgtattccct gcgtcaggaaactaggaagg tcatgacccc 300 caaacagaac ccaaggcccc agggagacag agggaccagtttggcagctg atggtggaaa 360 gtggtggagg cgggggtggc cgccaatttg gctgatccctcccctccctg tgcctgaccc 420 agctgaggta ggtggggaac agggc 445 14 245 DNAHomo sapiens 14 tttttcaaat tagaattctt ttaatataaa aaaaagtact aaaatacccacgtggttctg 60 ctgtgttatt tgccctaaag gaagtgaggg gcagagtgaa gaatcccagtgcagctcagt 120 gggcccagaa atggcgtttc cggtaggcta aggcgtgccc actccacctccaccagactt 180 ctatcccctc tgctgttccc agcccccaat tcctgcagca ggaaaccccagtggtctggc 240 tttgg 245 15 366 DNA Homo sapiens 15 aataaagacaagtgttcaga tttatttgga aattcacagt ttctaatggc actacagctc 60 cgtagttacatattgaaaat tctcttccca caacacacag atcacataat ttctcactgt 120 atctctgctctcatctggac ctcttttcaa ggggcttcta taaaatcagg ccctcttgct 180 ctgaatagctaattgtgcag acaggaaaga aatttaaatc ttctaaaaca cgctgttaac 240 ctaaagcagcaacttaaaca aacaaaaaag gcgttaaata agtcacatta caaacaatac 300 ccaagaaaggtattaggcaa gtttaaaaac agttatcact actaaaagtg ctcaataagt 360 tataac 366 16402 DNA Homo sapiens 16 agggagtatg gcatttatta accctgtgtt tcccccgtcactggtcactg ctcttgactc 60 gtagaacaac aggtacagaa ctgcaaggga tcatccccagctccgtgatc accagatcca 120 caagctctgg gggagtcaca tcatagacta gattcaacaaccgtagtgat gcgtggttct 180 gccagttagc cagcgcaaca tgttctcccc gcttacattgcagatcatca gggtcatcta 240 gctcattaga gacaaaggca tcagtctgca cacgctcacagaacttgtat gtttcacagc 300 aaaccagcac tggtacatta tgggctcgag caccagggctaactgtgctg tccctacccg 360 tgacatcaca gacccgttgg ccaaaagtgc atgagctccc at402 17 410 DNA Homo sapiens 17 gcgcacccaa gccggtttat ttggtctcccgcacacactc aggcctgcat caccggccgt 60 gatttctccg cttgcagctt cactccggagcccgcgaacg cggtaccgcc ccgctgcagc 120 acgatgatgt cgcggtctgt gagtttgtctccagtcacag ggtccaccat gtccttccga 180 atcagcttct ccacgcattc gagggtgaccacagccccag aggccgcagc acagcgcagg 240 gggtggcgtt gctcaggctg tcgcgggtcacggcacacac gtagcgctcg cttgcgggtg 300 atgagcccca cgcggtccac ggagctgtctagcggtgtga agtgcacggg cgtcaggtcc 360 gacatgcgca ggggcttccc tgacatggggcaggtcaccg tgcgggacgg 410 18 432 DNA Homo sapiens 18 tttttttttttttttttttt tttaaaatga ggttacctgc tttatttgga taccaagttc 60 ccttcagacagcattaaaat aaagacaagt aagactacac agataaaatc cagtataatt 120 caaatccaacaatgaaaaat ttcccccata ttgttgcaaa attctttcta ctgaaatgct 180 ttgctacaataataaaaagc atacattaca tataaaagat accagtgtac taaaaagtga 240 cagaagtggactagcaaatc cttcaaagca cattatataa atgactagca tttaaaaaca 300 ttttttcctataaaatgtag gtcatataca tttataaatt ggcggtttta tttctaaagc 360 agtgatgtgtgtgttcaaat agctgtcctg tacagtataa tatctactca cttgaaacta 420 taataggttt gt432 19 120 DNA Homo sapiens 19 tttttttttt tttttttttt tttttttttttttttttttt gcaggaagac tatgtctaga 60 gcgaaggcta cacagacccc acgatgggggagtggggcct gaggtgggag aggcctggag 120 20 470 DNA Homo sapiens 20ttttttaact gagagttttc tttaatataa ttgttgtaca gcaaggattc ctgctgtata 60gagtatatag aagatgacat actctaggaa ttagaacaat atatattcaa tacaataaca 120aaactatata gtactttaag aactctttca catatatgaa cactcttact tagaacttca 180gctgtttaaa gtaagcaata tgcaagccta taaagtacac accaaaaaaa tctaacctac 240aaaacaccca aagcaaatgt tagcatatct ctattatcaa gaatatcttc tcaccatcgt 300ttctttcaaa aatatgtgaa aaagttcttt ctttccttat gagtggcaat ttttaaaagt 360cccctcttct gaaattcaga tatgtttcaa atcacactat catcttctta aagaaaaatg 420aaaaccactc ctggctttta gatgctggga acatagttta ccacatattc 470 21 407 DNAHomo sapiens 21 caatctgttt gggactttga gggctggggt gggaaggtag tggaatggaatagataaaca 60 gccagtcaag agctgtgggg aggttgacag aattggggtg caggtacatgtaggatacac 120 agaagctttg tgtctgtgga ggctgtatga gtctgtgggt gagcagcatgtctaagtggg 180 tggaaacatg tatagctaaa ggcaggaact cttcccatac agctaaacccttgttcaagc 240 aatttaaata aacaagaaca ttttaaaaaa ttaaaacccc actaaaacaatccttgtgga 300 gcagttttct tgagtgctta agtagagacc agattcaaaa aaggattaagagaatgtcgc 360 ataaccaagc tgcagaaact gaaaccgagc ggggtgtgag gggagat 40722 423 DNA Homo sapiens 22 tttttttttg tattgcaaaa tgtacagcat ttattcacatacagacaaaa aggcacaatt 60 ctactaaata gttcaacaaa aaaatacagc tgtcctcaactagttttata aatactttca 120 aaaagggggt agaaataaat acaggattgg gtcatgtaatataaaatagt catctctaca 180 tatactttga tttttaactc ttcatgcacc tttttttttttcaattttag ctgaatggac 240 accaagctag gcacatagtg aaaaatcctc tgtacaaggttacaaatgta atgacaagtt 300 tgtccatttc aaaataagat ttgtacacaa cacataaaacccttcattta gatcttgtgt 360 ttataaccta acaaatgaca ttccaggcaa ctttacaaaagtttaactag cctacatttt 420 gac 423 23 386 DNA Homo sapiens 23 tttttttcctcctgcatata ctttattcac acatgctaaa tctcactaaa cagatcacac 60 tgtcaaggaagatggctaag gagaagctag ggttgtcaag gtaatccttg cttcggccct 120 gttttgcaacaaggtaataa acagccagaa cagactggag tgaagcaggt taagggtgag 180 gagagaacacagtgcagtgc agggtgtgga aggcagctca cagtcaggga ggcagcagtt 240 ctagccaatcaacactttat ttttcaagtc aacacctgca cagatgttag tgtccacttc 300 ctgaccctagtagggggtcc actacacttg gatcacccag aggagcagta aggaagctcc 360 taatctcaagagagagcaca tgctca 386 24 434 DNA Homo sapiens misc_feature n=a,t,g or c24 tttttttttt cctcagtagc cttgattgtt gaaggagaaa attacccagt tttaagaagc 60agttacccag atgccttttg tgtggcctat actctcccaa ttctaattca tgcattcttc 120aatgagcata gagcagttac tcctctaaag aattaagtaa ggaatgagtg caagtaaatt 180gccagggctg tcacttggat cactgacttg catcgtggtt tgcaggactc taaaccctcc 240agantttcaa tacagagcac gattgatttg tactgagttg actttgcaaa tctgataggt 300tataactgct tcagggaaag tgagaaccac aggaaatgag agcaagccag caagcatgtg 360aataaccttt gccctcccat ctccttaccc catcatggca aatttaacat atggacaaac 420cacattttta tana 434 25 463 DNA Homo sapiens misc_feature n=a,t,g or c 25tttttttttt tttttttttg atttggtaat taaagtttat ttgaacacaa aatactttct 60ctgtctataa aattggctgt tagcagtagc agcagcatgt cctggccaag gggagtagat 120ttctccagac tactaaagcc atgtatatag ccattcccac ttcccatatt ctgtggatat 180gtacatgtgc atggtagcta gagtccctcc accaggagta tctctctcat ggatggtttc 240ttcagggaga ggaagaggag acctggggtg aagagctggg atggttttga gtggggcaag 300ccattaggct gttaccttga agcccagtct ctctgggata gctgtactgc agggtgtcct 360ctgaggccct tctctgtact ctgtctggct naggggaatn ggggttattt tggactccca 420taggaaaggc acttagccta agtcaccaaa tngactgctt ggg 463 26 433 DNA Homosapiens 26 ggacaccaac tgcagcgtga tttattggac aagacgtgca cttttcaacagggcctcagt 60 aaccacggtt tccttcactg atcagtacag gaccagggta aaggggcttaaagataagaa 120 agacaaactc ttcccaggaa cagatgggga aagaaaggag gaagaagaggcatgtcctcc 180 cttcctcctt ccctagtact ctgggcctcc gttcaccccg tgctggagtggggctgacca 240 agggaagctg ggggcagtgt gtgtcacagc cagacatgag ctgaggctgtgactgtccac 300 tcagggtcaa aatggccagg tggacgatca actctgtccc cacttcaggcccccagatct 360 ggtcactgtt ccaggctccc cccacccgcc ccaccgtggg tatggttaaaaaatacaaaa 420 gcggattcaa tgc 433 27 452 DNA Homo sapiens misc_featuren=a,t,g or c 27 gcagtgggtt cttttaatta ctgaattcag tatgttagca ttttatttgggatttctgca 60 tttatattaa aatgtgcatt taatagctca ataactcaat ttgtcttatcagttagcaat 120 atacaaatgc aattattttt aaatcaacaa aaggtaacta aaattaaatctttcagtgat 180 gaatttgagc agagtaagag atctaataac aggttgacat aagaaatatttgtctcaaaa 240 atcaatgtat ttaatagttg acagttacaa atctcatcat tattgttccttcagtaaaat 300 ttaaatattc ccacagttct caatcaaata tgctttttca gttttccaacagctgtgatt 360 tttcntcttt tgggtctatt cagtagaaag tgaactatct gaagtagaacatcatcatta 420 anacctttca catcattatc cncaattggt tc 452 28 467 DNA Homosapiens 28 tgtgaatatg ggcggtgagt ttcctttaat caaagacaac catgacaaatttattaacta 60 tcaaaagcta cattttacta aaaacaatct gcctttaaaa atgttgaatcatacaatatg 120 tacaatacat gccgctttcc gttttggact tcactatcca tttgagtccttcagctagca 180 tcaagcactt ggcttctgct gcctctgact tggagtaatc acaggctctgaaatctcaaa 240 ggtcttcaca atctcctggc agacaataat gaacatttag gcactgggcttactgcaagt 300 gaaggcagag tcagaactat gcaggggcaa caggcagagc tttacctcccagtcacggta 360 actcaaagct ataattcctt gatttctaac ttgtgtggtt atggttcaaatccccccatt 420 ttcttcatta atacctaaaa gggcccggtt tgaaagacaa atttttt 46729 384 DNA Homo sapiens 29 tttcgggaac aataacatga gagtttatta tcacatgactactcaggagg ggacatgaag 60 cggcagcgat ggggaagggg tgtaaggaat gggcaagtgctgctggagca gggctgtggc 120 acggtcatgg ggccaggata actggggctg ttgaagagcctcttttcctc agtctggttc 180 ttcttccagc agtcagatgc agggacgccc ggtgcagaagcacaaggcac taataatcag 240 gagaggcatg gctagattcc actcacttcc aacatttccttctggtctct tttccctttg 300 gttgggaaca ttctccagca gtacagccac agaggggtcagagattccag aagcagcaga 360 atccagacac ccaagagcat ggcc 384 30 211 DNA Homosapiens misc_feature n=a,t,g or c 30 tcaatattta ttgaaatact gaaaaaaaantccattttnt tgagaagttc ctggcaagaa 60 ctgacatgac aatatgtatt tcattgatacagtaagaaaa catcaacaag taactgactt 120 cgcactctaa acattgcatg gattcaagtccaaggcagct gcagatctgt gatacaanta 180 atcagncatt agngattgtc tgtttacaaa c211 31 404 DNA Homo sapiens misc_feature n=a,t,g or c 31 tttttttttttgctgtgaaa tcttttattt ttgttttatg acacagcatc aatttcatga 60 atactttgaaagggccatta gaaaaaataa gagccaattt gggtcatttg agaaacattt 120 tcagcacaattacagtgggg gcacgggccg ttcggctcca gctgggtttt cccagatgca 180 acaatcgcggttctggcttc tccactggtg gggatgggga tcgcgccttc ggagctctca 240 gggcgcctgtctgtcggggg ctgggtgcgt ccacagcccc gggggatggc gcgtggctag 300 ccagggaacggcatntgggg tgggtctctg acctgcttnt gcagggactt gagggacctc 360 atcccgatggccgaggcagg ggcttcccac gggataaaaa ggat 404 32 411 DNA Homo sapiensmisc_feature n=a,t,g or c 32 aagtttaatt tcagaaaatt atagtcccag gntcactctcagaaaaccac aggtttttag 60 tcatttctgg nacaccaatc ccaaattata cagaaaaaagaccaaaatgt ttaaaattaa 120 ctgacttggg ggaggttgga gttcccttcc tcatgcagaccggagcatcc atagaatgtc 180 tatctagcct aaggggatat agantgcacc tgattttgaggggtctggga agagagggat 240 aaagagaggc cacacagtcc aaccaacacc ccaggcaggattcagtttct gatgcttgcc 300 tgaaggcaac aaaggacttt ctggaaanta aaaaaaaaaggnaaaggnaa aaagggcagg 360 actttacacc tcatcaccgg gggggncaag ggcggggagggggggttttg a 411 33 471 DNA Homo sapiens misc_feature n=a,t,g or c 33ttttnnnnaa tagctaccgt ttattgggca ctgcaatgtt accaggnact attaagcact 60ttaaagacat gacttcattt catcttcacc acaactccat gaggtaggtg ttatgatccc 120cacattacag atgaggaaac cgaggttctg ggcactgatt tcatttgttt gaagtcacac 180agcttgtgag tggtgaggct ggaatttgag cccaganggg tggaacccaa ggcagagctt 240gcaaagttgt gacatcagta cagtgtgtta ttgtacccgt ccagggggcc acagccctcn 300accttccttt tcaaacccca ttntcaggga taggggtctg gaaactcctg cctgcagaaa 360aggcttgtgt gtctccctcc cgggtnggac ctgcatttcg ntttggttnc tatcagaggg 420aatgaagctg aaatcgtggc aacgtnaggg cagttgcctg gggtggggga a 471 34 383 DNAHomo sapiens 34 gaaaacaaaa atttattgct tctccttcca aagctttgtg aatttacaaaaaaaaggatg 60 aaagtttaca aactgcttag ttccaactaa gcataagagg tgagaacgtacactgcaggg 120 ccaccagcag cagctgtgca ctcgatcgtt aaaactggct cccccagacttgtagtgctg 180 tcttcagggg gctgcattcc ttacacgcca cctcttgtga cataggtcattggtcaagcc 240 gctggaatgc tacagaggtt tttttggttt tgagaggctt ttttttgttttgccttccta 300 ctataaaagc gaaattttca gttcatttct gaaaaataaa ttggtcaataaattcatttt 360 gttctgcttc tactttacac aaa 383 35 327 DNA Homo sapiens 35acagatgcac cagtggattt tattagtgtg aacgcagcag cctcgtcgcc ccgggagctt 60agcagggcgt cgagggtgag cagcgtgtct tcccgcactg tgtcttcgct acagaagttg 120tacactgtct tctcttctcc cttttgcaca gtgatcttgg tggcacccac tttggggagg 180gttggattta tcacattgtt attccaaaga aacttgactt tctcaattgt tccaacatcc 240agctttgcat caaactcata ggaatgggtt gagcctggtt tgagaatccc cctgaagatg 300ctgtactggt gagtgtttcc cttattt 327 36 173 DNA Homo sapiens misc_featuren=a,t,g or c 36 ggcaggtttc cttttattgg ttctagacag tttgtggaag gaagagatgaggccatctag 60 aggccggcag ntcgcccagt gccccaaaca ctgccaccct gaagtagtgttggaagctgc 120 tccagggatg ttgcagccct aagcacagtg acaggtgggg gcaggagcagcag 173 37 426 DNA Homo sapiens misc_feature n=a,t,g or c 37 ataaagaaaaatgtttattt tggctcatgc ttctgcaggg cgtacaggag gcatggcact 60 ggcatctgcttctggtaagg gctcaggaag cttgcagtca tggcagaagg caaaagggta 120 atcagcatatcacatggcga gagagaacaa agagctgcca ggctttttaa agcaaccaga 180 tctcatgtgaacttagagag tgagaatgta aggttagccg agagaaagga ccagagagag 240 agagccccaagttcaggcaa gcctttatta acctgtcggc tgccccctta acagtcaagg 300 aaagcagccccaagcttaca gaataggggg tttacattng gggcagggag tttgagggag 360 tcctttggtatggctncatc ccggggttgt ctgctggtta atttctgcca catatcacct 420 tgtgaa 426 38410 DNA Homo sapiens misc_feature n=a,t,g or c 38 tttacatttc ctgttttcattttattggga acttcaaaga aaagaaagag agacggattg 60 gttcccaaga caagccgtgacgtagactcc caacaagctg gggaattctg gacagcnaag 120 gggtggacag tgagactcagcacagcccaa agtcaaaggc attagggttg ttctgaaaat 180 agagattcaa gaagccctggaaaatgctct tatccatgag aagagcacag actgtggggt 240 cccacttcat ggctgatatccagagccgca ggctgtgcgt gtggctcaca cagtccagta 300 tcccatacac atccagccgctcaaaccagg gccagaggag gtaatcaatc atggatatac 360 aggttccacc aaagaaggtggtgttctgat actcaagaat ctcttccagg 410 39 142 DNA Homo sapiens 39aacactgttc attgatttat ttaaattaaa aaataattgt atatggtaaa tatctattaa 60gtacaacatg ggacaggcac ggtgcctcat gcctgtaatc ccagttcttt gggaggccga 120gacaggcaga tcagttgagg cc 142 40 114 DNA Homo sapiens 40 ttcttttttttaagcttcca cctcagtgtt ttactgagac cagcattggg gcatatgagg 60 cacaaggaatccagctctgt tccctagaag ccatccacaa ggttttcctt gtag 114 41 172 DNA Homosapiens 41 gaattatcaa actttattgg cttgttaaaa atgattgaat tcagcaagtacatttatgat 60 ctatctacat tgttaaaaca gcactaaaaa taaaattttt taaaatgattatccattatt 120 tacagaaaat gtggaaaaga tggcttttaa acccagaaca ttataggaaa aa172 42 404 DNA Homo sapiens 42 tttttttttt ttttttattt tttaaaattgaacctttttt tttttttaaa aaaagcacat 60 aaaccctaca tactaaaatt atacacatcaagtactggtc caatcttata tcaatctatt 120 tacaattaaa cagcaccatg gttttcccacctaggttagt taaacatgcc cagagaattg 180 ttattcaaag catatgttcc tttaaaataaaataaactct taaaaagaga gctcaaatcc 240 tcaacaaaga aagacctttt accaatcgatatcatagata ttgatgacat caccaaattt 300 gcttaagaaa aaaacagttt taaacacttttttccagttg acaaactttg agaagtgctg 360 ctattcgatg tggcacacaa atgaacaaaaactttgatga cagg 404 43 405 DNA Homo sapiens 43 gaagctttct agaaagtctttatttttctg ttatgaataa ttgcattttc taattatccc 60 aaatgatttt ataaattccgtaacttttat atgcctgcct gggatccatg aaataaaagt 120 attccttacc aaaagagaagcatcagatac actgaaaggc tcaatgtttt atattttcag 180 acataaaagt gactgtatacccttttatta actatatggt agcttggtaa aatttttata 240 gaatttttaa tgatctatggtgttctatga tgaggcaaca ttccaccaaa ttagccttcc 300 aaaagttgca gtatcatgtataattatgac agcagttttg ttttaaaacc agagtcagat 360 tgaatgtagc ttttttacagctgaaattta tgccttatgt gtatt 405 44 318 DNA Homo sapiens 44 tttcacaacaaaatttatta gaagaatagt ggttttgaaa actctagcat ccagtgagaa 60 ctaccatacacaacattaca gctgggaatg tttctccaaa atgtcatggt caaataatac 120 aatggaaccattaaatctta cacatgcacg aaagaacaag cgcttttgac atacaatgca 180 aaaaaaaaaaaaaggggggg gaccacatgg attaaaattt taagtactca tcacatacat 240 taagacacagttttagtcca gtcaaaaatc agaactgcat taaaaaattt aatgtagtgc 300 aatcaaaccaaaaaactt 318 45 437 DNA Homo sapiens 45 tttttttttt tttttttttt ttttttgtaatttaaacttt atttcatatc tattgttaaa 60 ttacacaaaa tcagtgaatg gtttgtaaagctacaccaat ggacagatgt ttacagttga 120 aatcatggga tttacataat ggcaaaaatgtatatgtata tttataacat cctctatata 180 caataatcag tatagacaga gaaaatgcacttaatctttg caaatcatgc acaccacagc 240 aataacacaa aatgtttttt ctgtaacaagcttttccact ggctcaggct tcatcctgct 300 ttccaacaat acctatcagt tttaaaagcaaacattttca attaaaacta aagaaaattg 360 aaataccata gtgatctact aactattttaaaaacacaat tgtacacaaa atagttttac 420 tctaaaacac tgtgact 437 46 188 DNAHomo sapiens 46 tttgagaaac gaggctttat ttgctccaac agatattaaa agtatgagaaccacaaccat 60 gaaaacaaca gaagctgatg tgagaaacaa cactaaaatt aaacagtgcagacacaggtc 120 cagcgacaat gattttagca ctcatacagg tggcatttcg gtcagtgcatgatgattcag 180 tgggcgaa 188 47 497 DNA Homo sapiens 47 tttttttcagtattttcctt cactttaatt tttattgctt ctccagttca gataattcag 60 cgcttcctctttcttcttcc tcaccttgtt catggctggc tgttccatca gcagaacttc 120 cagcgattgccacattcatt gcataagaca aaggtagtca tgggctcatc agcactgcgt 180 gtctgcacctggttataggt gcagttcttc ttcttgcatt tgctgcactg gaagaggtca 240 gtggtggtgccgccagtctt ggccatctgg tgctcacgga tggcctcctg ggtcatggca 300 ttcctcaactccctcagttc atcactggcc atttcctctg ccgtcatctt ggctataagc 360 ctgcggagatggccccactg agcacgttcc gccgcacgcg gggttcctgg ggtccttgag 420 gttgcttatgcggctgcgca cgcggttccg gtacttcatg tccgtgctct tgagctcttg 480 gtagatatgatcttcga 497 48 330 DNA Homo sapiens 48 tttgcacttc ccatgagcat ttttattaaattgaaacaag ttgttgattc gataattaca 60 agacttgtac aaaaattcac agcgcctgtgaggagccttt ggtgtgaact ggtgacacct 120 gtgcctctcc ggacagagga aggaagtcccaccccgcctt ccagcagcag cgagcctgtg 180 tctggcattc cctgttccgc tgctcccaccctcactgtgg ggcagcagtt ctttaggaac 240 attcagctgt caaaggtgag aaccagccccacaggcctgg gcctcgcagg cttaaggagc 300 acttgttggc actgttagct cagcacctct330 49 358 DNA Homo sapiens 49 tttttttttt tttttgacat ttgtattttaataaaggata ataaaagcca aattacagcc 60 aactgttaaa gctttttttt tttttaaattctatggtaac aaaatcagtt caggggcttt 120 ttttctgaac aaatgatcat gatccctcagtctttcccgt ggcatgctcc taaaacaacc 180 ctctatgtct aatcagtcac ctaagatattgagtggcaag tctttcacag ttgctgctta 240 taattcctaa atggtccata ttgagtattttcatttctgg gtaagggaaa aagcattttg 300 gtccattaat tcacccactc gctcctggaggacattaacc aattctgcta ttacgaag 358 50 473 DNA Homo sapiens 50 tttttttttaccagtttata tagggacaga acacacacag aactaagcct tctggattat 60 gttaaccaccaatattatag ctcaccttca tcaaagtaca gacaccagat agggaaaagt 120 ggatgagaagggaggggaag ggcaggcaga ggcagcaggg ttatgtcatt gatctaaaca 180 aagttttctaaaccagattg tgccatcaat caaaatggtc aaaccgattt agactttcaa 240 catctccagtaggaagtgag cccataatta tatacattac tctgcaaaat gctattggat 300 ttttctttgctccatccaaa ctctatgtaa tcaggtgcac ctcaggctat agtttaagga 360 ttatgggaccaaaatcttca tatgttcaac gattctgagt acaaacagaa gttggggaca 420 aacactgtggaaaacagctg cattcctttt ctgcagtata tacaccaggt att 473 51 589 DNA Homosapiens 51 tttttttttt tttttttatt tcttaatatt ttaattatca ttataatttggcagtaaaaa 60 tcacttttca caaagacatt acacttacat taacaaatca ctcttgattcattcattttt 120 gtttttccat ttctcctggc agctttgtaa gaatccataa cttcaatatgtctaactcag 180 ttttgcttag ctcatggtaa acatttggaa aactatgaaa cttcgtggtcactcctagag 240 attttaacat tgagtttgtc tcttctgccc aagaatgaag aactaactcatctgcagtac 300 catgacactg aaataattca ggaagtacac cattactctt ctgaagagcctggtaaacag 360 cagatgcttt attcagaaaa ctagaaagag caaatactcc tgccacatcttgatgatttc 420 tatatgctaa atgcattgcc atgcatcctc ccatagagaa tcctcctattaatatcctgt 480 tcttcttgat gccacttttt acttcttcat caatcaaatc agtaagcacttgacacatga 540 catcaattga ttcaaggtgt tctgggcagt cattggttat tttaaatct 58952 371 DNA Homo sapiens 52 tgttggccag gctggtcttg agctcctgac ctcaagtgatccgcccgcct tggcctccca 60 aaatgctggg attacaggca tgagccacca tgcctggccaacaccaacct ttagttactt 120 gctgaataca caggattaag gaggaagaga aagtatcaaggatgactccc aggttcctag 180 cttggtggtc ccagtaattg agagagagaa tgcagcaggaagagcagctc tagggggaac 240 aggatgagta tctccacatg atgggttgga ggtacctgtgagtcacatcc aggtggatgt 300 gtcctgtggg cagtgggacg cgatctgaag ctcaggcaagaggctagagt tacatctttg 360 gagtcatcag c 371 53 216 DNA Homo sapiens 53tttttttttt tttttttttt tttttttttt cttcgtagga gtcttttatt ttttggtgtc 60ttaaatgtca atgatcacaa aaacttccgg gttctcttca ttatagacct gcattgctga 120atatgttatt gctttgactt ctgttcccta aagttggggt tagagaaaaa aaaaaaaaaa 180aggaaaatag gatattgaaa tcataatcat taactc 216 54 339 DNA Homo sapiens 54aatttggaac acaaatgctt tatttaaggg tgcatcacaa ttcccgtgtg gtgagcaaaa 60aataaaataa aggagcagat cgtagcacac cattcccact ggccaagtgg ttgaaccctg 120catccaagac ccagtgagca gccaagtgag gtgcacctct gggcctctca ctcatgactc 180camcagaatt agcacattgc ccttgtgcat ggggcctttt acattgcaga ttttggagca 240gcaagacaat gtatatctgt tcgtamctct tgttctyccc tcctgatttt taaaactgcg 300taattataaa actatgttga tggacatata attattata 339 55 242 DNA Homo sapiensmisc_feature n=a,t,g or c 55 gatcggtcat gctggggcca aaaacatggc aagaaacgtcccactgtcaa cctcccgggc 60 aagcgtgtgc acctgcagct cagggccagc ccaccacactgccttagtga cactgcagcc 120 gggggagcca caggccgcca gcaggctgag gaacaatgccgtgtgacctt tccnncnnnn 180 aaaaaacaaa aactgcaatt tttattcaaa taaaaaaagggtaaaaataa aagttaataa 240 gg 242 56 252 DNA Homo sapiens misc_featuren=a,t,g or c 56 gatctccctg ggctacagtt aaggaacaag aaaggaagct tccttggattagttaccaat 60 tctaagttca gactctacag taaatcatga cgacagttag gggagccagccttggaataa 120 aggtgacaaa gaggacagca cagtacagac agggcaacat gtacctgatgatgtcactca 180 gctgctaagt cacatgtctc tacctttgan cttccagtta atgtgagacaataaatttna 240 tgttgtacac ac 252 57 156 DNA Homo sapiens misc_featuren=a,t,g or c 57 gatcttgttc acaagtnaat ctgttgacag tgccaattaa atgataataaaaaaattaac 60 atgtcacaat gtaacggatg accatatgca caattccatg aattaaatctgtttcctgtg 120 ttagtcagta ttcttaaata aaatttataa ttgaaa 156 58 123 DNAHomo sapiens 58 gatctaaaga gaaactgtag attgttttcc tgacagcaaa agactaatgtgacaaaatga 60 agtcattgta aagaagcgat gcaacttgtc aaatatttaa taaagaattatggaagctgg 120 aaa 123 59 268 DNA Homo sapiens misc_feature n=a,t,g or c59 caatntgttt gggactttga gggctggggt gggaaggtag tggaatggaa tagataaaca 60gccagtcaag wgyttttgkk tggttkwyag aattggggtg caggtacatg taggwtacac 120agaagctttg tgtctgtgga ggctgtatga gtctgtgggt gagcagcatg tctaagtggg 180tggaaacatg tatagctaaa ggcaggamct cttcccatac agctaaaccc ttgttcaagc 240aatttaaata aacaagramc attttaaa 268 60 264 DNA Homo sapiens misc_featuren=a,t,g or c 60 gacagatcaa ttgtaattta tttnctttta acactgtatc atcataaagaaaactggtat 60 aaatgaaaaa atctatttca aatatctaca tctaaaattt taggcagtgaaaaagcactt 120 tgttgacaag gagtgtggaa tgatgtatgt taattgtcag aaactgctgaatgccttgtt 180 tagttgtcac aaacaaattc acatatcaga acggacaata ctgctaaatattcctttttt 240 cctgcttttt tttttttttg ttaa 264 61 246 DNA Homo sapiens 61ggccatattt ttatttacta catatactat aaacatatac aatacatgct accaaaaaaa 60attttttttt aaatttaact gtcaagaaag tgtatagtgt tataatacaa tggcacatgt 120ttatatttta tttcaaattg gtttgcttat cacctatttc aaaccattaa cagtgaaatg 180ttacttgtgg ataattaaaa attatctatt tgcattatta acaataaaca attccaacaa 240attaat 246 62 395 DNA Homo sapiens misc_feature n=a,t,g or c 62tttgttactt ttacatgatc tttattattt aagaaaaacc tcttttaacc atttatataa 60cagaaaaaaa atagggaggc tggtagatca tcacatatat agtagctaaa atatgaaagg 120ccagggaatt tattattaat gaagtcataa aacagactta accaaaagtg tgtgctagga 180aacaagcagt ttcacttcag agacttcatt gcaggaaccc agtttcctta tgtggaaaaa 240agtgattata aataacagtt atctgaaagg tggttgagag gattaaatga gatcacctat 300gcaaacaaat acatgtaggt atgaaagacc atccgtcctg ggggtngtgg aaagtttaag 360tttccccncc agaacccttc cctttaaggg cctta 395 63 432 DNA Homo sapiensmisc_feature n=a,t,g or c 63 tttttcacaa tgccgtttgt ttatttactc atagctatttccttccaaaa ataatgcaat 60 gtcgcttttg ggaaaaacat acaaaggaca aaaaataagtcgatgaagga tcagtgaaaa 120 aaagaatgta caactggttg ggttgctaca cagaaacaaatacgataaag ttctatacag 180 gagggagaga tgggtcataa gtatgatagg gagcttcccagtagccaaag caaagacaaa 240 acaattgttt caaaatttcg catatccata agacaaaatcaaacctaacg ggcccgggaa 300 gaagccagtg attatanggc tcctaaggcc tggagaccaaaattcctccc cagtaagttt 360 tttttttaaa ggacttagtc cttaacgnca ttttccccggtangggcgat attggtccag 420 ccaagctttt cc 432 64 447 DNA Homo sapiensmisc_feature n=a,t,g or c 64 gcagaattgt gtttattggc atagatgctt atgatatattgttaattgaa aaagcaggta 60 acaaattaat atacagtatt atgttaatta tgtaaaaaagtatacatatt catagaaaaa 120 gtttggaaca atctcagata tcatctgtag gctatttctcgtttgaaaat aaccaaatag 180 atttttgggt tgactcaaca aattatggtt gagtcagtcttactttccta ttttataaat 240 gttttttaca tcattgggta tttaatcatt ttaaaaatctactcaggcat catttgtata 300 atagtaataa taatttaatc ccccttattt ctcatgtctcatgccttatc catcatccct 360 catatcctac tcttagccca gattttcctt gacaggcttattttctggga ggggcaggta 420 tgggggaacn aaatttgttt ccttacc 447 65 413 DNAHomo sapiens misc_feature n=a,t,g or c 65 gctcttggaa atatttttattnggttctga gataacaggg ctgaggcgag ctgggacggg 60 cgcagagnaa cggtgggaggctttgcctcg gggcggacat gctgtgtggg gtctgctggc 120 gggctccctg gcccacccagccagcagcag ctgggcacat ggcccttggc gcctgggcat 180 gacctctgcc ggcttggcacggtggcctcc tcgtcggcgg gcgccccgtt ttccagttgc 240 aggagttagt ctttcacagtgcggaggggt nggggtccgg ggtgggcgcc tccccggggt 300 gcaggcaggc cccatccgccagtacatcct ggggctctcg gcggctacag cgggttgagg 360 caagctctaa gctcctcttaagccccgcct ttgggagctt ggcagtcctg gag 413 66 401 DNA Homo sapiens 66ttccatgtgt taataccatc atcaccattt aatttttaac ataaacttta caatatgtac 60aattttattt ggataataca cttacgtgtg aattgtagaa atcaagcatg tatattatat 120acatgtgtac acaagcagtt gtattcacag gataagtgca tttgatcatc tctgatctat 180atcaagtggc aagctgacct catctgatac aattagatat gaacacagta caatgtatag 240ggattgaatg ggaaacagta actgcatatt gggagaactt ttcaagtata gaccccacag 300cacttttcaa ccctgtttca ccaaaaagag atggggtatc tggaaaggtc taattttgtc 360tccagtgaaa ataaacagta cttttggaag gaaaattgcc t 401 67 477 DNA Homosapiens 67 agactgcttt taaattgctt tattaacttt acagtatgca ataaacatctttccatgaaa 60 gttgatgaaa gtcctcttct gacagaaaaa cttacagact aggtcaaaatgcaatctcca 120 atcagaaaat tgcagaagaa tgccaaaagg ttcacattaa aggtacaccaggaaaaatgc 180 gaatttagaa agcagggatt ttatgattat taacctcaag attcaaggcataaggcaaaa 240 ctcatcatga tgatcatggt gaggagggtc ccctataaga atgcgcagactgtacctcaa 300 ctgaagttcc ctaattttcc tccttagctc tctcatctcc tccatgaaccgttccatatc 360 atctccatct ccatctatca tatcaatgtt atcgacaagc ctattgggcacatcctctcc 420 aaaacccggg gcaggtggag cccaaacccc tttaacattt cctccaggctcctggta 477 68 460 DNA Homo sapiens misc_feature n=a,t,g or c 68tttttttttt tcctgattta aagtatttta atgcgagctg ttaagtatgt tagcatctgc 60ctgggttctt atcggtcagt cattacatag accccaaatc ataaaggngt tctagtttta 120tatctatggg gaaggctgga aaattaccac aaggggagag agagaaggtg gtgtaaaaag 180gcagcctaac taactatttt taaaagcaga tcaggagata caggagctag gtgagatgct 240gtggacagtg catgaggttc aattgtgaaa accgatgtcc tcattaatga cagagagaac 300tctgtccctc catatacttg gctgggcatc atcagtccag ggtctcttat acttggagtt 360ttccanatgt ttggtttcat gaagcacact ttaccaaaat ttaggaaaag aagagaaaga 420tctccaactt ttaaggtaat atacttttgg ccataaatan 460 69 317 DNA Homo sapiensmisc_feature n=a,t,g or c 69 aacatttttt tatttttatt tttttgtgaa aaagttctgatgtcaactca tgtttggtat 60 gatagatttt aaagggctaa gatatagaga atcacattcctttccaggag ttacttttgc 120 tgttatgtcc ttctggattc tacaatataa atctactcctagaacatcac attccttctt 180 tcatttcttc ttctctcttc ctttcttttc ttatttgtctagtagagata agctataaaa 240 ttctaccact aggcaattcc aatctgaatt tcnttttttcataatttaat tctttaaatt 300 atctgaagtg ggattag 317 70 455 DNA Homo sapiensmisc_feature n=a,t,g or c 70 acataaaata ctctgttttt tattaactga atattttcttaagcataata atagacaatg 60 aaagaattgc acttattata aaggtacagt aaagtgttagattgcagctc agccatgaaa 120 gatcagggac tgtaggacag atgatagatt gtgcattatatgcaaagatg atggtggcca 180 gtgaaattaa aatgagagca actagttaca gaacaaacagggggataaca gaagaaaaca 240 tgcactactc ctactttaat gcaaaactaa tttctcccaggaaaccaacc ctttgacctc 300 tctcatacaa agaaacgggt tctgcacccc taagcaacacagttagactt gggacttgtg 360 tattcaaatt gctagttcac tgtctctgag cgtgctgctccagtgacatc tccgtaagct 420 ggccctttga cattctggga gcaactacaa tattn 455 71139 DNA Homo sapiens 71 tttttcaggc ttccgggtct ttaatggggc gggggctgggggcagttcat ccagaggtgg 60 ctccgaagct gaggtcaacc ttggcggctg gctcgctactccagggcctt caccagggcc 120 tcgttggctc gattcggat 139 72 438 DNA Homosapiens misc_feature n=a,t,g or c 72 ttcggcagcc acaaagactg ggatttcnaattctagttat gataagtaga caatttaagc 60 catttatcct tttttctgtt tccttttcaagaaaagaaaa tcgtattttt ataaaatatg 120 atcatgtcag tttggtctat ttttatatgtgttaaggaga gcaataatag tcaaaagaat 180 aacaatataa cgattaggta tttagttttaaaaaaaaaaa aaaagtagag gatggggcaa 240 tagatagcct gcctcttctc taaccaatttgttaactgtt taagaaatta acaataaaga 300 atatggcata tggaggccag aatgttacttttatcatgaa caaagttgga ttncggagaa 360 tgcagcttat cncctacttg gcaggcagatggccatctta attctatatc ccagaattta 420 ancaggtctc ccagccac 438 73 466 DNAHomo sapiens misc_feature n=a,t,g or c 73 atttcctgaa tctttttaatggttgcattg tgttctactg tatggatgca ccattcccaa 60 tcagttccct attaacggatatttgggtta tccctaactt ttgctatgac aaatagcact 120 gcaataacct tgtatacctattgtttccat gtgtggagct gcaccttcag aataaggtta 180 gggttagaag tataactgcaaggtataaga ataaacacaa gtaattttgt actccgtgga 240 acttgaacca tttttccactcccaccagga aaggtaattt caacgtgtat ttccattgta 300 agtgaggtgg agcgactttctatgtttaaa gaccattacg gtattttttc tgagaatcat 360 ctgttcatgt ccttccccattttctccttt ggcttttgca ctttttgttt tcaatttttg 420 agagctcntg tgatacgagttgcnaagatt ttctccagac cgatct 466 74 164 DNA Homo sapiens 74 gcattattttaagatcttta ttattaagta actcactggg gttgtcaaag tatgttataa 60 aattacacagataattagag atatatgtta catagaaatg ctgattttac actctcttct 120 gagtacaagcatttgattac agaggctcat agcacaacaa aatg 164 75 299 DNA Homo sapiens 75tttatctttt catcaccatt atttattata tatgaaccag gttttcagca caagtcacac 60tcaacaccct tacccaacag gaggggcgac ggaggctcag agagggagtg tagggggagg 120atgtcaatgg gaggccccag cctgagccct gagcagctgg ccagccagga actggcattg 180ttgagtgaga ggcatcctag tctcctgctg ctgcaaagac aatgcccgct gaacaggatg 240gcaggccaca tcagcagtcc atacagaagt gaggctgtcg tttcttcccc tggagcacc 299 76407 DNA Homo sapiens misc_feature n=a,t,g or c 76 tgtaattttg ngnattttttttatttagat actgatgttt attttccatg ttgcttaaga 60 acccgtgcaa gaacagcttaagaccttcca gtggttgctc ctacccattc agtggcctga 120 gcagtgggag ctgcagaccagtcttctatg gcaggctgag tgctccagtc ttcagaaggg 180 aactgctgaa gaggcacagaaggcacctgc atgccttcag atcagtgtgc aacctcaggc 240 tgagtagcag tgaactcaggagctggagca gtccattcac actgaaattc ctccttggnc 300 actgcctttt cagtagcagcctgctcttct tttttaatca cttcagggat ctctgtagaa 360 gtagagttca ggcatgacctcccatggntg ttcacgggaa atggngc 407 77 444 DNA Homo sapiens misc_featuren=a,t,g or c 77 gagncnatct cgtttatttt ttgtatatac atctacatac attttatacattatattcat 60 atatacatat atacaaatgt atatatgttt aaagccacgc tataagaggaagtaaatgag 120 aaacagacaa atgaagtggt agctggagga cgtgggaatc agtacaggttttcacgcctg 180 tttcagaaat gggagattct acagcacgct cgacactaac acatcacatccataacatat 240 cacatccaat agacaggaca gccaaaaaca caaaacaaaa aaagaatcaaatacccacac 300 ccagacacaa tactcaacaa cacaaatacc cgaccaaagt ctttaaggaaaggcaaaaga 360 ggctggggca cagtgggctc acacctgtta atcccaggca ctctaggggggccaaggtgg 420 ggtgggaccn cttgagggtc aggg 444 78 453 DNA Homo sapiensmisc_feature n=a,t,g or c 78 tttttttttt ttttttcaga ggtcaaatca cttttattctttaaggattc agtgtaacat 60 ccttttcttt aataaaataa ttaaacactg gcagaaattaacttattcaa aaagtcatac 120 taatactttg ttatgacttt ttatagaaaa acaaactttatttttttatt tttttgagat 180 ggagtcttgc tctgtcacct aggctggagc gcaatggcacgatctcagct cactgtagcc 240 tccacctccc aggttcaagc gattcccctg ccttagcctcccgagtagct ggaattacag 300 gtgtgcgcta ccatgcctgg gctaattttt gtatttttagtagagatggg gtttcaccat 360 gttgggaagg ctggtttcga actcctgacc tcaggtggattcacccgcct tggcctccca 420 aagtggctgg gattataggc gtgacagcct gna 453 79436 DNA Homo sapiens misc_feature n=a,t,g or c 79 gatttgcata gttgtcactttattatatta ttttccttct gtgacctttc caagtctgaa 60 acagtcccag ggacttcttttggttagtta tttgcaatca ccgaattgat ccagtcgatg 120 taattggaga cccgcgtgaagacggagggc ttgtnggtag tagttgcagc cgaggcgang 180 acccgaagct gacgatgccgtgcacctgcc accggccgtc agatgcctga cagttcagtg 240 gcccgccaga gtctccgttgcagctggaga tcacgccatc acccccaagc acagatcata 300 ctggttttca cgctgctgccccaccaaggc agagctggag caggtggcat agtccacaac 360 cagcaaccgg ccctgctgcaggacatcagg aacagccccg ttggtctgca gccttcccca 420 gcccgtgacg tagcag 436 80428 DNA Homo sapiens misc_feature n=a,t,g or c 80 gacctttatc aataggacttattttaatga ttaccattac agaaaggagg ttggttaatc 60 cccaaagatt ccttatctgtgaaatgagga aggttacaat aagaatgtga atagagtact 120 aacaccaagg aagtgaaaatactaacctca aactcccatg taagcatttg ggggatacgt 180 gtagtgataa gtacaaaatacacagtttaa taagagccac ccaaatagca atctttatat 240 tcattcctta tctcctttgcacatgaaact ccttgttggt tttaatcacc tctacaatta 300 atagctgaag accctattngactactcttt actatggatc caatttaatt aggaagaaaa 360 aaaaaggcag ctttaaggggacaaatttat ggacttaaaa atgggttatt ttaatggaag 420 ggcattag 428 81 593 DNAHomo sapiens misc_feature n=a,t,g or c 81 tgcatgcatg aaaagctttattaagtcaat aagctgttac acttttacaa actgctatgc 60 agagatactc aaacatttttaaatgacatg agaaactact aacatcttta gtgagagtca 120 ctttcacaat tttctctgctcccacacccc taatgatcaa catattcatt tttttattta 180 gtatatgtca cgcagcaatttatcaaaagc ttttgttgtg aaaacacttt tcttaaatac 240 acaattaaaa gatatgattaagcacttaca ggatgtgaaa tatttaaagg taatacacaa 300 taatcgggtt accaaaaggaccgccttcca atttttcttt ctattcattt tgatgttttg 360 ttcttttcaa aacattttctctcattacat tcattactaa aggccttact ttaaatacat 420 catgctacat tttgttctcctcttcaaatg ccaatgtttt aacaatttga antctctggc 480 ctgggaaaaa gaaaagtnatccacntacaa ggtanaccgt atggacacca nggatgtnac 540 aggtccaaca acagcccaaatccaccatgt acatgtaaca tagtgaatga gcc 593 82 294 DNA Homo sapiensmisc_feature n=a,t,g or c 82 atgtaaatat ttaaatttta ttcttaaata ctatttattaatacagagaa atactcctgc 60 tataatttta agtgacacaa tagtacaaca attgttaagaacaatccacc tgtgtcaaag 120 agacacatac acaaacacac atccatatac acatacaagcttggngaaaa ttctgaaagg 180 ntctcattgt cctagatggt ggcattatgg gcaattattttgcaaatgtc acccagtgaa 240 gaagcaatgg tgcctttgga aagtatgtag ctcttagttaagcttttatc tgga 294 83 511 DNA Homo sapiens misc_feature n=a,t,g or c 83tacacacact gtttgaaggt actttattaa gatcaaagat ttttcattac atttatttat 60aaatccttcc tagtcaaaat aaaataataa aaatctgtat ctttagaaag aacatagttt 120tgtaagtctg agaaggttat gtttgtcagt ttcaaattat tacagtttag atacattcaa 180tcattacaca ataccaggaa ggtcagcctt aaagatacca agaacttcca tattggtcag 240taaaataagg gtaaaaaatt aaattttact ttcacctttt tatgtttgat tgactacagt 300caataatagg gagtaccaga atttaccttt ttgggtcttg attttttaaa tatatggaat 360ttttaaaaag tgaacggtnc ctccttcctc cttaccataa gtgggctcca accttanggg 420aagctgggct tcctggaagg gaaggaagtg cnaattccnc cctggcnggg agaaaggagg 480ccggggggaa gaaaggtncc gaattccggg g 511 84 470 DNA Homo sapiens 84tttttttttt tttgtttttt aatatgcttt attctgcata ttagtatcac attacacagt 60ttggtcatgg tatttgtaac ctggagagaa tactagtgca gtcggtcttc ataccacccc 120attcacaacc agcttaaatg gcagtatccc tctgtgaact caactacccc tcctgtgggt 180ccaggctgag ctctacaggt cagcctcttc atctcagccc ttctaggtcc tgctgtcagg 240gctgagctgt cacttcactt ttttcccaga gtagtgcagc atcctctctg aaacctgagc 300tatcatgaca ttttcttttt taattttata atttttatat ttctctaatt tttgatttta 360gagacagagt ctcattatat tgccgaggct gaccttgaac tcctgggccc aagcagtcct 420cccacctcag cctctccagt agttgggact gcaggcatgc accactgtgc 470 85 567 DNAHomo sapiens 85 tgtatgttga gagtctcttt aatttttaga gtaaatatga cacaatggatagctttagaa 60 caagctaaca ttactacagt tcaagcatgt gcaactggta cagttcagtagtacataaac 120 gactcaaaca aatgtacgac aggtcagaaa cttaagttac aaaatagagtcaatattaca 180 attaacacag agaagtaaaa accattgctc tcagattctg cacacttaaaaaaacataaa 240 ctttatacag tcattgaaat tacgcatttc tactcagatt attagagcatattacaaaca 300 cacagaagcc taaacagtta tggtcacatt ttggttttgt tccagtggtgcacgatcaca 360 tgaaatgtta catccgtttt gtgtgaaata aacatttggc tgaagtgcaatagctgctgc 420 attaaaaata tttccataaa aatgcttaga ttaaaatctt cctgaacattagggttctaa 480 tgttcaggat tattttaaga gtccttatga agagtcctta aaattatagaaatagatgta 540 gttaggaatt tcagtgtgtt tgctgtt 567 86 435 DNA Homo sapiensmisc_feature n=a,t,g or c 86 tttacattct aagccattta ttcaacganc ctatagagtataagtatacc cantacctca 60 gactgctttt ggcccctgga ctagaccctc attgctccaggcatgagggg ctgtgcaccc 120 tgacagagcc acccagggcc agtgntgntg naanatttgatcaatggcta taaccgcttc 180 atctgccgcc gctcctgtcg ggctgcgttn tctcattgtgctctggtgct ggggtgccac 240 tgtctgcagt gaaccagggg cccagcacat tcacccacaggaggtaaagg gcccggcctg 300 gagccagaag ccagaaggac cagacataga gagagaagcagctgagcacc tgcacgatgg 360 ctgtcagtag gatcacatcc ttaaggtgcc tgtggatagaaataaagctg gaangacagc 420 atatgggcct ttcca 435 87 588 DNA Homo sapiensmisc_feature n=a,t,g or c 87 tttttttttt tttttttttt tttttcttag agcaaacaaaaaattttatt agattatata 60 cctgagcaat agaaaacttc gagataacat tttaaaaatattgacacgtt aaggagtatt 120 ttactttcaa aataccataa aattgatttt aaattccctttggaagaaaa catcccctag 180 tctccttcac taaattacaa ataattaccc aaatataaaaaggacttgca atgtttgtta 240 aatatggacg gcatgaagac aattaagaaa ctataggacttatttccaac aagaatacaa 300 tatgcatgaa gttttgaaaa tgtgactttt taccacagtttctgagagtg taatagtact 360 aaatgttcta aatgtaatct ttcagatcca cgagcggtgaaagtaatgct ggtttggaaa 420 atgaggttga tactccccgt taagcttctc agtgaatgggctgcttctgt ttctaagctg 480 caggaacaaa gcacctctat ctataagcnc ataaacacacaactcaacta tccagatact 540 ccggggccac aatctcaatc tagggccgta aaaattcaccaattgatg 588 88 512 DNA Homo sapiens misc_feature n=a,t,g or c 88gtctcactct gttgcccagg ctggagcaca gcgttgaatc ttggctcact acaacctcca 60cctcctgggt ttaggcgatt ctcctgcctc agcctnncaa atagctggga ttacaggcac 120atgccaccac acctggctaa tttttgtatt tttagtagcg acggggtttc gccatgttgg 180ccaggctggt ctcgaactcc tgacctcagg cgatccactt cccgacctca ggtgatccgc 240ctgcctcggc ctctaaaagt gctgcaatta caggcataag ccactgtgcc tggccctatc 300ccttttaatt ttctaagtga ccagtaataa acaatgattt gtttattact aggtagcagg 360agaaaaactt tttagtcact tttccagcta agaatttcat ttaaagatac ctatgacata 420tcttgtggta ctaagaatat tagagaactg gaaatccagt ttttttgtgg ttttttaaga 480aagagaatct gactccattg nccagctcgt gc 512 89 404 DNA Homo sapiensmisc_feature n=a,t,g or c 89 aaaaaaatca tagaaccata atttatttta agccctaaaatgaaattgtg aaccattaaa 60 aatatgttgt aaaactattt aatgtcataa agagaactaactctgttttt atggtccatc 120 taccaatgtc ttccgagcag ttctctctcc tcaaacctcctctacctctt tactcaccct 180 cactcagcct aaccttgctt ccgattttat taaggaaatccaatcaatca gaagaggttt 240 ctacaattta ctatcacatt tacccaccag ccatcacctctgccatatat gctcctctcc 300 tattccaatg gctggaatgt ctcagggaag accaagcccttcacttgtac attagatccc 360 agctctctgt cncatccatt atggaagctg cacatcancccagt 404 90 290 DNA Homo sapiens 90 actctcactt tgtagtggta tatttaggatttgatgtgac acagttattt attgctgagt 60 gagcaaaccc ctagccccca agtggggactacaggcttca gtgcttcccc cacactgcct 120 gagctaccag cccttctgca ctggccctcctgccaatact gcctgcactg tccccactcc 180 ctctggctcc catgatcacc agatccgccctgcaggctcc ctgtcacctg tggggcccta 240 tccagacccc ctaatccact tgcctagcagccccactctt ccctcgatgg 290 91 241 DNA Homo sapiens 91 catgggaaaacttttcttca ttctcaacat gcttaagcta tttttacaaa tcagttaaac 60 tatgtctacacaaagcttag aagcacttta tttgggagca atcagtattt ttgtcaaaac 120 ttttggacaggtctttattt gtgttttgga aggttcaaca cgaattgtgc aaaatctctg 180 gatatattagtttagcgata tggttgttga agaaaataat atgttttaag cattcacaac 240 g 241 92 144DNA Homo sapiens 92 cttttttttc actttgaaag aagctcaaca ttttcttctcattttcaata acttaaatga 60 acagcactta acacattaca caaaattaaa gacttgtgcatatatttgat ttcaacatta 120 atgtcaaaaa tacatagtat gatt 144 93 313 DNA Homosapiens 93 gagacggagt ttccctcttg ttgccaggct ggagtgcaat gacacgatctcggctcacgg 60 caacctccac ttcccaggtt caagcgattc tcctgcctca gcctcccgagtagctgggat 120 tacaggcatg caccactagt ctcgcgacgt tttaattaga attttagaattagaggaggg 180 ctagaactct gccctcattt ttcagtgagg aaactgccca agacaggacaaatacttacc 240 ctaatgctta gcctggctcc agtgaaatta gctccccagc caaagctgagctggatggaa 300 ctaacaagga cac 313 94 248 DNA Homo sapiens 94 aagggaaaacattaatttta ttagaacttg aacaaatgtt tcacaaagaa aacattttaa 60 caaaatggtatggtggcata acaataacaa aaaagagaac agcaaaatgt gtaaaagaaa 120 tataaggtggaaaaattgtt aagtatctca taatccagtg tggaaataag aagtctaaat 180 ttaaaaacaatgaattttaa aaagcataac tataaaacaa aagttaatgc ttgtgctatc 240 ctaaccac 24895 238 DNA Homo sapiens 95 atcaaaagtt tgttttattt tcaatacaag ataaataccatgcttgttac tagtgcagtt 60 taaggccgac aatggccata tatcaaactg ccgaacagtcacctaaatgc taaagaaagg 120 aaagacaaag taaacattaa acacaaaatt gcaattacaaacattttaat aaaatggaat 180 gagcttttta attgaagcta atatgaagtc taattctcatggacagcaaa aaaaaaaa 238 96 163 DNA Homo sapiens 96 aatcaaaagg attctttattatgtagattg tatcataatt catcaaaata attttataat 60 taactgccat actgtcttataaatgatgcc ttctgaagtt aaacataata tagattcagt 120 tttttaaaat gatctacttacaacatacta aacaaataat aga 163 97 247 DNA Homo sapiens 97 ttttctttttaatcacttta ttgcttgagt acatagacaa atttatgcaa ccagggcgac 60 gtgtagatggttcatatttc cagctgggag ggaggactcg cttggtttta taatatcgag 120 ccagacggtgaatccggctc tctatcagaa tcagaaggaa tttagcatcc ttgtcttttc 180 tgctcctctcaagatgcttt tgaacagcga ctgctttctt aattaagtgg tagagatctt 240 cagggag 24798 399 DNA Homo sapiens 98 atagtattat actttgttta tttaaccctg gatcaatataggtatcaatt cagaaaattc 60 acaccagatt ggggattggt gggagaatgg ggaggagatgatggtcaaag ggtacaaagt 120 ttccattaga caggaggagt aagttatgaa gagctattgtacaatatggt ttctacagtc 180 aataataata tattgtagac ttgaaaattg tagccggtcacagtggctca tgactataat 240 cccaattctt taggaggctg agactacagg cacaccccactacattccta gctaaatttt 300 aaaaatctgt ttgtttattg tagagatggg gcctcaatatgctgcccaag gctggtctca 360 aactcttggc ctcaagtgat cctcctacct tgtcctccc 39999 399 DNA Homo sapiens 99 ttttttttcc ggcactaagt caagttcttt acttcccagaagtgatggct aaggggaggg 60 aggagggtga gaagaggaag acagaaagag ccagagagaatgaggaggtg agaagggggg 120 gacagtaaac cactgttcta tgaagtctca cgaggcaagtgctcaaggta aaaaaagagt 180 cctggagaat cgtccacggc tgcgggaagc atctcggtttccttctgctt ttaagtcctc 240 tcagggaagg ctgtcgccgc tgccgctgca ttaaatagttatgtacatcg cagagagtcc 300 caggccatgg gcaggtgggg gaggggcgtc atttcaccaggggccgagtt ttatcatcgt 360 caccgcactg gtgagctttg tactttttca cttctgcca 399100 468 DNA Homo sapiens 100 tagagacagg gtcttgctat gctactcagg ccggtcttaaactcctgggc tcaagcgatc 60 acttgcctcg acctcccaag atcctaggat tataggtgtgagcgagccac catgcctggc 120 cttaaaattt ttttaacaac tacctgtaag cactcaggacttagaaagta ttttgactaa 180 tatttaaaat tttaaagttt ttaaaaattt cttttattcatagaaattaa aagaaaacaa 240 atagcctctt attttttaaa ggagggtaat tctgaaactaatattttcta tcaactacgg 300 ctggtgatgg taaagttcta tatattaatg ttactttttcatatatatct ctcttaaatg 360 acactttggc tttcgttctc tcaatgttta tctctggggaaaatgtgatt aagataatca 420 gtattttagt atatatcaaa agttctaata taagttttcctcatagtt 468 101 400 DNA Homo sapiens 101 tttataagta gttagatcattttataaagg atgaaaagac aactgcgaat tttaatctta 60 gaggtatatg cagaatgtttacatgcagtg tatgtatatt cactatttag ttccattttt 120 taactactaa gaaaaatagcaaatcaccca ctaactgcag aagagcaaat gtaggaaaat 180 cagtatttaa tgaaaagtctagccattctc taagcttgaa aatcaacgtt tttttagcat 240 tgcacttaag ggcaataatattacaaagtc tgaatcttca tttactcaaa gagaagaaat 300 taaattgatg aagcccacttgattgcagat aataaacagt tattggcagt agattcttct 360 actcatgtta tgctttatgaaactgtccac ctaagtccac 400 102 243 DNA Homo sapiens 102 tttttggagcagtattcaca ttttttattt cgaggtgtaa aatatacgtg gccaacattg 60 ttactttcatccacagatgg aatagctggg aagtataaaa acctgtacat gacctttagt 120 gaagattatttgtcatcaaa ttacccatat ccaagtttcc atgggcctgg aatttccttt 180 ccacttgatagaagtatata ttaggaagtc cagttaataa tatttttatt taaaaaaaaa 240 aaa 243 103294 DNA Homo sapiens 103 tttataaaga tttaatttat ttaaatcaca taagattattcaaagccata ggcatgatta 60 agtctctata gaatcaagaa gattttctgt gtggagaatatctcgtggag atttgaaatg 120 tgtcgcctct cctgagcagc caggattaac tctgcttaggacgtttcaga taagggtcag 180 gctggcgtcc ttctttctgc ctccatgggt tgccaccttttgctatgtca ggggggtcgc 240 ttgcttaaga cgttgcaagg agcaccccaa atgccaggcttcccaccata gctg 294 104 407 DNA Homo sapiens 104 tacaaagaaa atgttttaataaaatattca atacagtatt tccctgtggg attctagaag 60 aagaagtgag atgctgaaggaagtgactgt cactgtgggg aacccagtcc taaatgagac 120 aagacttagc tttccttcaaagacaccttg tccagctctg cccaacaggc cgcaatgaga 180 tggaccagga aaccttcaggagtcaccgac agacaaagcg aatgaactga atccacttac 240 aaacagatcc acttaagcagtttttgcctc aggcttccta ccaaatgcag ttatcatgga 300 gaccggagaa ggctgatgtacaaaacgcat taacatgatt ttgttttttc ccctcctatt 360 ctatttgcat ttccagagtgatcattagta acacagcgat ctgggtt 407 105 401 DNA Homo sapiens 105tttttttgag aatttttatt ttattttatt ttattttttt attattatac tttaagtttt 60agggtacatg tgcacaatgt gcaggttagt tacatatgta tacatgtgcc atgctggtgt 120gccgcaccca ttaactcgtc atctagcatt aggtatatct cctaatgcta tccctcccta 180ttttatttta ttttgaaaca cggtctctca ctctgctgca gtgcagtggc acaatgttgg 240ctcactgcaa tcgctgcctc ctgggctcaa gagtttgaga ctagcaagag gttgaggttg 300tattgagcca agactgcgcc actgcattcc agcctgggcg acagagtgag accctgtctc 360aataaataaa taaatatcta aacaaaagac agaagatctt c 401 106 77 DNA Homosapiens 106 tcattttaga cctaagagtt ttttgttata agacacccca gttaagaaatattgaaacat 60 aagagacttg accatca 77 107 576 DNA Homo sapiens 107tttttttttt ttattaagaa agcagtttat ttcttaataa ctgaatgtat attattttac 60atataattaa tgatcagaga gaaataacag ttgctgagaa cgtaaattta tgttgtactt 120tagaattgaa cagatacaac cacagattca taccaaatgc attactttta gattattaac 180atattctttt acataatttc atttcacata tatggagtcc aaccaagata catctggcat 240agtaagtttt catcagtagc ttcttgtata aggtaatgca catgtccttc aatagataac 300ggcagtcctg tcactctatt tcgagtcttg attacacctt gtagtcgctg ctcaatgtca 360agaacaaggg gccttggcct tttcattggc aacttctcca gtttcattca gtggggcttt 420ggaatgccct ttcactggtt tactccattc cacaagagga tcatgtagaa aagtctttaa 480gacactcatt aaaggctctc gctgatcacg catcagcctc attgtaactt cacatgctct 540tcgaaaaaga ccctctgttc ccataggacc cattcc 576 108 208 DNA Homo sapiens 108tttttttttt tttttacaag acagagaaat ctactttaat attcacatgt aaaagttaca 60catcacaaga gattggacag tagcttagcg taacatagct atagtgaaaa tcatttttat 120aaaaaaataa tctagatgcg gtcatcagaa tttttggtct gcttaagtta atgtttgaag 180atcgactttt atccctgctt gaaggatt 208 109 356 DNA Homo sapiens 109tttttttttt ttttaaatta cccaatctca gatattcttt attcttttat agcaacacaa 60acaggctaac acaaacatat tgagttttta gttttccttg tgctaatttg ccttattctt 120cacaatcaca ctacaaatat cgtcagtcct attttacaca tctgcaaact gagagaatta 180gcaattttgt ccaagagtac gctagtgaag tggtaaggac aggatttgaa ctaagaccct 240gattccaaac cctttcgttt taatatggag gcttttcatt cctgcttgag aagaggaatc 300aggacacaga ggtagactat taattggcag aacagaggac ctccctcctc ccctcc 356 110531 DNA Homo sapiens 110 gggtagtggt taccatagct tttactgtag ttattcattaagctattcaa ctgttctgtg 60 cagtttgatg ttttatttta caataaaaag tcaaaaaaaataagcaaaaa gataaactgg 120 aaaataagac ttacatctca tatatatgga caaaggaccaattacctcca aacataaaca 180 gctcctagaa attactgcaa agatcaacaa cccagtagaaaaatgaatga agttcccaga 240 acagaaaaca caagtggccc ttcaaaaaaa tgaagagaggctcagcctct tatggtaaga 300 caaagagaca ggattttaaa aacctaggcc tcttcctagagttcccttaa atatctaggc 360 cagatcattt ttacttcctg gcttagaccc tgccaagggctgcccagcta ctcaggtgtt 420 tgtgtccttg tggactcaag tcatattgtc ctgatcttttggctgagtac ggttttctcc 480 tccagcaaag acaatttgga ggatgtacta agcatgaagcgctacttcct g 531 111 469 DNA Homo sapiens 111 tttttttcaa atacaaatatactattttat tctaagggaa tatttctgtg gtttctgtaa 60 ggggaaaacc taaaagtggttaaaaactga aaaagaacaa aaaggatgat ttagatgttt 120 ttgtttgatg tttttttctcccctggaaaa aaaatgtaat tttacacaat tttcataaaa 180 ttaaaaaagc aataatcagacgcacacatc aacagctaca cttatgagga atgaccaata 240 attaatcaat attttctcttatgaataaat ttagggttct gggcaactct gtggactaac 300 atgcaaatga aatcctgatacagtcattta tctgggtatt gggtgttctc agtaaaagat 360 acagattttt ttttctggtatttcataaca atttatctac tatgctaaca atatttgttt 420 tttcatacaa ctacagaaggggaaaatgtt agtgtttata caaaccatt 469 112 355 DNA Homo sapiens 112tttaaagaca atgaaaatat tttattcgtg tatccactca ttcgttcaac aaacatttat 60tgagcagctc ctatatgcca gcccatggct aggcttgtgt gtccaaagag gcataaggtt 120gagcccctac actccaagag tgctcagcta ttaggaaaga cctatgcaaa aaacagtgcc 180atcctttatt acatgcagaa aacacagtgg aagcactgcc aacgggagga gagtatcact 240aataggtact ttaaaaacta tgtgttccag gggccccgga tgcagagctt ccagactaag 300aggtcaccaa agggaggaga aagagtaggg cacttctggg aaataaaaag atgtt 355 113 374DNA Homo sapiens 113 cttttgttct caacttgttt aatatggaaa aaggtcatcaaaacggtagg cagggttgct 60 gtttttaata cattcttggg atgttggcca ttcagacagcattatttcaa atatagatga 120 gttatccaac tttttttgac tcaaagatag tttgcttagatttttttttt ttgagatgga 180 gtcttgctct gtcaccaggc tggagtgtag tggcgtgatctcagctcacc gcaacctccg 240 cctcccaggt tcaagcaatt ctcctacctc agcctcccaagtagctggga ctacaggcat 300 gcaccaccac acccagctaa tttttgtatt tttagtagagacagggtttc accatgttgg 360 ccaggatggt ctcg 374 114 417 DNA Homo sapiens114 cgtgacgata aagcttttta atcacctagg tgcaggcagg ctgagtccaa agagagtgtc 60agcgaaggga gataggggtg gggccgtttt ataggatttg ggtaggtaaa ggaaaattac 120aatcaaaggg ggttgttcta tggcaggcag gggcgggggt cacaaggtgc tcagtgggga 180agcttctgag ccaggagaag gaagttcaca ggttaatcgc tcagttaagg tggggcagga 240acaaatcaca atggtggaat gtcatcagtt aaggcaggaa ccggcccttt tcacttcttt 300tgtgattctt cacttgcttc aggccatctg gatgtataca tgcaggtcac aggggatatg 360atggctttgc ttgggctcag aggtctgaca cacatcacta agcattgttt gatctgt 417 115316 DNA Homo sapiens 115 tttattagga taataattct gatgctttat ttgtaggggatatgtctcta aaagggctgt 60 tcctcacaga tgtctcaggc caccttcaat taaacccaagcctcttcctc ttctactgaa 120 gcccctgtga gtaaagtccg tggaaatcat atagttctagaggctgggca gtccgagatc 180 aaggggctgc atctggtggc agctttcttg ctgcatcacctctgcctgaa aggtaggact 240 agcagagaac tccaccaagc agtacagtgc tcaggttagaagcatgaaat tcgaaaccag 300 acttcctggg ctccag 316 116 291 DNA Homo sapiens116 ttttttgagt tcacgaagag tcatttaatg ccttttatgt gccaagcact gttctaggca 60ctggggacac agcagtgaac caaatagcag tgcacacgga gcttacgttg tagtagggag 120aagccaggca gctaacaggt agacagtaac taggtagcca ccaagatggg gatccggctc 180tggagaaagg catagcaaga cagagaggct ggggagaagt ggggcaggca ggttgttttg 240tattatgtag aatggtcagg gagcacctta ccaacaagat gagatttaat g 291 117 371 DNAHomo sapiens 117 tttttttttt tttttttttt tttgtctttt aaaaaatata aaaatgttattattttaaaa 60 catcaagcat tacagactgt aaaatcaatt aagaactttc tgtatatgaggacaaaaata 120 catttaagac atatacaaga agatgctttt tcctgagtag aatgcaaacttttatattaa 180 gcttctttga attttcaaaa tgtaaaatac caaggctttt tcacatcagacaaaaatcag 240 gaatgttcac cttcacatcc aaaaagaaaa aaaaaaaaaa acaatttcaagttgaagttc 300 agcaagaatg atgtaaaatc tgaaaaaagt ggccaaaatt ttaaattacaacagattgtt 360 caatttgatg g 371 118 204 DNA Homo sapiens 118 taattattcaaatttttttt aatttaaaaa caatacaagc tgattataca tttgacaaat 60 acaaggaatttctgactgca ggaaaaaaca aagcatcaac tacaaagrga agcagaaatt 120 cttcttgagctgctgatttt actatacatt tgggctatat yyytycttaa gvcaatcact 180 amaaagtaataatataaccc cctt 204 119 161 DNA Homo sapiens 119 gatcaggctg ctgagggaataaatttaatc aaggtctttg caaaaacaga agcacagaag 60 ggagcctata tagaactaacactgcagact tatcaagaag cactcagtcg ccattctgca 120 gcttcctaaa aatattttaaaaatacattt attttactaa a 161 120 428 DNA Homo sapiens 120 atataaatacatttattggt ggtattcctg aatgatgaat gcagagaaca gaatacaaag 60 ragtcagcacataaaaggra tcattaatct ttaaaaatgc tatatactta cattttgmcc 120 mattttgcmtatttgtttag rtttacaaac aaatgtaaag ctaattccaa agttttctyc 180 tgaatatacttcaaatttga attgtagtgt tctccattcc aaagccagct gtttttttgc 240 tggatttacaccaactatga tttactttgt ttgtatctaa cctaaaagca agactctgca 300 agctgatcctgaagcagcca gttactcagg aattttacaa cagctattaa agagaggata 360 aagccacatgaaagagcaag cctcaatact agatacatag atacaagrga aatmccaagg 420 agcaaaag 428121 317 DNA Homo sapiens 121 aagmcacatc tatttattta taatcaatcc actgtgtataamggratact atcagamggc 60 aagtataagc cctaagkgct accaacactt atgttggkacactttgtata tcacactttg 120 atacaacact ttgtatcgga atacagagaa agavgaacacatcccacagt gcataaataa 180 ccatatttaa cacctctcaa agactttgta tagatcaggcaggttagcaa gctkcaggwt 240 atttccatct tctgtgaaat ktttaggggg cagaatgtgtgagcscaagg ctttatagac 300 aatgtgttcc mcagtcc 317 122 396 DNA Homosapiens 122 attgctgaac accaatatgt cactttatta tttggvttty byttcccatttgtcacatac 60 ctgtcaatgt tacacaatgr gggaaatcaa ccagcattgg aagcaactgaccaaatcagt 120 tgataattct gtaccctctt aacacacatc aattttcact tggtagggattatcttaaty 180 cggtctcaca gctattctta aaattggtgt caagattgyc acatctttaawtacagwtag 240 ahttgccaga rgtacatawt tatatatvtc tvbsccacat acagaaamtacaagactgtt 300 tcccacaata tttaatttat acactactgt aactatatgc mccttttgaagacaggttaa 360 gggghacaag tactktttag rgcaagwaag tagttt 396 123 333 DNAHomo sapiens 123 gaaagctctc aaataagcsa ttttattcct atccatgatt gcagacatttacaaaaccat 60 aacatctgag ttcaccttaa aaaataactt atataaagca gtgatatacacagcacaaaa 120 tasttcasgg agggggcagg vgcaacttgt aataattaaa atgtaaacgtgaaaaamagg 180 wtggawtaaa agtccctact tatttctact taagatgtca tgtgataatatttyacaatg 240 tcctgtgggt catgtatgta tgtstatats tctgtataac atacacatatacagtacatt 300 ctctctccca cacatataca tacacacata ttt 333 124 224 DNA Homosapiens misc_feature n=a,t,g or c 124 acattaagca caatacagca atttatttagatgcttaaaa tgaatacaaa gggaaaataa 60 agatcacaaa attatacata ctacaacagtgtgtcatata ttagatggta taaatgantc 120 caccatgatg gtgttgaact aaagataaaactaantatcc aaaatncagc actcattggt 180 ttnctgcttc ancacaacac acttttatacagntctaaaa ggtg 224 125 349 DNA Homo sapiens 125 ggtcatttta tttttattacaacttcatta tttacaaaac cccccatcca gatatattca 60 cgttaacaat tctgagataactgctgcatc acagttgcac aaaggctgat gagttgcaaa 120 tgttcatcag caccatctgctaggcatttg tcaacttcgg caagtttttc tgtgataata 180 gacttctgtt tatcagataagttattttct acaaccacat catggagttg attgacgagc 240 tgagttgctg catgaccctcatctattaaa tccttgacca cagcttctag tttgtcaaaa 300 gagccactct gacaggcagcaaatactcca tcaattttct cagctgggt 349 126 386 DNA Homo sapiensmisc_feature n=a,t,g or c 126 cataaaaaca ttttattcac aaaattggtcatcacagcat tatttacaat actgnaaatc 60 tggaaatagc ctaaatttct aacaattgaaagaaggttaa gtaaattata agactacaca 120 ataaaatata ttaccagcaa tatatctttgtgaaaatcta taataaccac acataatact 180 tagtaaaaaa gcancataaa ttacatgataaagcactatg accagnanca atgncaaaaa 240 attcacaccc ccaaaaaagn acaaggatattatatgggca attttgtggg taaaatatta 300 catgttattt gtgnctggca tttctaattttccccgttaa ctggacacat ncggttttcn 360 taattagggg gaaanaaaat tacctt 386127 443 DNA Homo sapiens misc_feature n=a,t,g or c 127 tccatcatccttaaattctg ttaccaaata atggctaatg ttacaaaaag ttatactcca 60 gagacccaaagcttgacatt tacctaatgt atgagaaaat attaccaatt aacaataaag 120 aatgatcatatttttaacct cttttacata gcctaataac tcagcaaggc ctcaacgtct 180 gtgctaatttaaactgccaa atattgactg cagcaaacaa gaattatatt cagaatttat 240 gagggtactgttaggngtat actgcttaca ggtttagata tagtctgtta gagttaaaac 300 caagtttaggtgttcatatt tacctcatgg gctttatcaa gcccatatta cctcagctta 360 tatatagttaccctttttag ggttttaatt gtttggcccn tgggtnggta atggcagtct 420 tttnttcttcaggggcttaa att 443 128 438 DNA Homo sapiens misc_feature n=a,t,g or c128 ngaaaatatt atatgtaatg actgtagtaa ccagtttatt acacagatta atcattcttg 60aaagtacaag ctccagaggc aaatttgggt ctttaaatat acacaagtat ttccatcaaa 120tgaattttca cccttacatc caaatagacc taagcggtta aaaacataag aaaaataaga 180gctattagct atgtattaac tgagaaacca catacaaacc aaagantatg gnngagagaa 240agaagggctg aaaggccaaa ggttgaaggg gtagggagat gtaaaagagt tggggnacaa 300agcccatcac acttgatgta ctaatagctc caatccnttt aaatgttgac cngttaaact 360tagaccttaa aatgcnggat gtggggtagg gtttaatctg gttggtcata actttcacct 420aggcgtagct ccttcggg 438 129 432 DNA Homo sapiens misc_feature n=a,t,g orc 129 aatttatgat tttattgtct tncctttgtc cggcctttaa catgtttctg taatttaaat60 aaaaatctat ttactttctc cattttagca aatggtttct ttacccaaat aggttgcact 120atagtcccca tatggttttc tactgtncca caaccactat ttcacaaaga ttgacaaaac 180tttaataaaa gttaaattta cagacatctt aagataactt gggaaatatg taggtaaaaa 240agaatcgagt ccacaantta aggantattt ngnctaatat gcccaacacc antttcaggc 300aaatccaatc tacttaactc atatatttna tgtgggggaa ttttncctaa caaantttan 360gggggggtat ggaatggnta tatttatggc ccttggacaa ggtggacngt gtggttttgt 420tgtgacaggg ag 432 130 245 DNA Homo sapiens misc_feature n=a,t,g or c 130agtaaaatcc attgtagttg catctggatt gaagagcttt aatcaaaaag tgtattgcac 60cacagatgaa tttgctacag cagttttcaa gaatacaatc cctatttaca acatggnagg 120ngagctcaag atccatcgct cgtataaagg gctatagata ccgtcgctaa cacagaaagt 180tttntacaag tcaaagngca ttaaatcact tngnntattt attccactct tcctcttaaa 240gctga 245 131 393 DNA Homo sapiens misc_feature n=a,t,g or c 131ggtgtccgcg ccctgggcct cggagcgcag gcgntccccg aacctggcgt ggaaccccgg 60catcgcctgc ctcacacctg gggtgtcggc ccagccagga tgcatggaag aaaaatggat 120ggccgggtgc ccttgggcca ccgctccgtc agaaccactt gctgcctctc actgaccttg 180ttttgtgcat agaccatagt tccatcaaat ggtgttcttt cggactggag atcattggtg 240ttcagtttct gaaccaacat tcctcctgag gagacggtta tcactcgggg gtngtgttct 300ttctccagca caggggatca gggccggtcg tgagaatgta cacaccggag ggggcagttc 360cctccnttcc gagggatccc ttcaaggcca atg 393 132 381 DNA Homo sapiensmisc_feature n=a,t,g or c 132 gctgctaaat nttgtctttc tttattcacagatgatagtc aatgggcaca acatataagt 60 agttacaatg aaatgagaag caatatagcagtcaggctat atgcatgatt taacaacaaa 120 attatcactt ccttttaatt tagaataagggacaatttaa aaagcatctc ttggccctat 180 catttctgtt ccagtagtta gtgttcatatgtgaatacna agttttgaca ttcctttctc 240 ccatagaacc attttggtga tttggatggtggccactaca ctggctttct gcaagaattc 300 agtcacccag gcctgatata gccttggataacccacgagt cngtgagatt ccagatactt 360 cnggttccaa aatggcnatg g 381 133 443DNA Homo sapiens 133 caagtttgct attgtatcag aaacatatct tttagtattaacagtttcca aaggattatg 60 tcttccacat tccttatact gatagatttc cccttggctatgatttccct gatatgcaaa 120 acagttccaa tccatggtga catgtatata cattcttaatatttataaat ttttacttgt 180 ctatagtcta gtattgttat accatgtggt cttgttataatcatggtttc cattctgtga 240 gtcttcagat tatgagtcca acacacaagg ggatgtccacactaacctgt gtgaactctc 300 tgatgtacaa ggtgtttgac ttcaggcagg agtttctgattcactatact gaaagggttc 360 tctgatataa aatgaggtct gacttcagag aagccttcccacatctatta cattcatatt 420 gcctctccta tgaattctct gag 443 134 390 DNA Homosapiens misc_feature n=a,t,g or c 134 tttttttttt tttttgctgc ttaaaaaatgcattaatgtt actgctttat tcacactaat 60 tagaatacat acacaaaaaa tgtgtatcatatatcacttt caaaaatttc catgttccat 120 gagaactatg taaacaatgc aaaatgtttccactacgtaa caaaagaaaa tcagcattcc 180 cacatagtat taggaaaata tttggataatctgaatttat agtaaaacaa agtgatctga 240 atttgtagta aaacaaagtg aaatattacaaagcagtctt gtcatgaagt agccttatat 300 aactcagaag caacacattt catactttcaaacactttgg tataagtgaa attaatagna 360 aacaaaaaga agaaggaaaa aaacctctac390 135 472 DNA Homo sapiens misc_feature n=a,t,g or c 135 gcatcataatgagtaaggat gtcaataatt gccatgaagt acacctcctt cctaggcgag 60 ttttcatggcacttaattcc atagacgtcg atgttcggat cgaactcccc gggagccagg 120 ggtggtgagctgttcagtgt attcccgggg ctatctgggg gggttcccac cgggtggtng 180 ccatcgctctcgccctcctc ctccccatcg ttctcctcac actccacttc ctcctgttcg 240 gctctctccacatcatgaat tcccaccagc agactgtagt ccatgagctt canctgggcc 300 agaaactcaacatccttttt tagtttttcc aggaagacct tcttgctgtt gtcatcaata 360 taaatcttttggccctcatt aatgaaatca ttatctttca gagttgggca gttctttggg 420 ccttttctttggtcactagc ttctctagcc actggtagag ccctttaagt cg 472 136 476 DNA Homosapiens misc_feature n=a,t,g or c 136 cttttttgat agtcatttat tttttttataaggttgaaca cttagaaata tgaccaatga 60 cagattaaat tcacaataat cattttttacatatgagact ttcatgcact agagattaaa 120 taagccctga catcaaaagc aataaaaactcaataaaagg accaaaacat tagagcagat 180 agaaaagaca gcaagaaaca ctttaagaaaatgcttccta ataagtttat tttctatttg 240 tttgaaaata caatgaagca aactgtgtaaattcagttaa attactcaag aaaattaaag 300 ctggaaataa tcaataaaca tttctagtaaaccatgtaca cagtaaacac attcctcact 360 ttcactggaa cagcagaggc aaccggtttctaagttccag ccactctttc atagagctct 420 ccaccttggg ctgacagcta aggatttctccagcgcactt ccntccccaa attcat 476 137 476 DNA Homo sapiens misc_featuren=a,t,g or c 137 aaaattttct ttttaattct cagcaagaca acgtacttct atagaagggtgcacccttac 60 agatggagca atcgtgagcg cacacttgga caagggaggg gaaggggttcttatccctga 120 ggcacgtggt ccctgctgct gtatggttcc cctattnggc ttgggttagactgcacaggc 180 taaactaatt ccaattggct aatttaaaga gagtgacagg gtgagtggtttggcgggaaa 240 aatggttaca gggcagatca ggaaatcaga gtaagccagg gtggagaatgagcaggtaat 300 cagaatgagt cagggtggag caggtaatgg aaaaaggttg ctttacgaggaagttaagtt 360 taacagtaga aggcaaagaa ctgaacatac tgacatattg attcnttgaagagaaattta 420 gaactcatac ctaacagtac ctngagaatg tgcatgagcc attccctccgcctgaa 476 138 404 DNA Homo sapiens misc_feature n=a,t,g or c 138tttaagctga atgcgcctaa ggagggcact gtttaatgac atgtggtgca gccatgcagt 60gaaatattac acagcagttc aggcctcagg ggaatcggat gagagactga gatttgctcg 120ggaggtttac tggggggaac actcaggacc aacacctgga aggatgtgga agaaggagaa 180ttgagtagct gcggttaggc ctcagctcat catactgaga gctggtgggc ctttcagagg 240tacctgcagg gcaaggagac aagacctttt tacccctgcg tcggtcagcc actggagcat 300gtgtgcctgg gcaggggctc agttgtgagc tgtcccagca gcagctcggg gaatgagtgc 360ctcatttgct gaaggggata gtagtggtct ggangcaaca aaac 404 139 486 DNA Homosapiens 139 tgcagttctt ttatcggtca ggatttcttt aagtttattt tttatttcatcctggcgatt 60 ccgtagcttt tccacccgtc ggtaacactc tatctgctca tcgatctccccaatctggcg 120 gtccaaccgt ccctcctcat cctcttcggc aactatggct tccggaaatagtgttgacct 180 gcctcatggc tttttggaat tcgtcccact ctttgtccat ctgatcttttggagcatcaa 240 cctttcgtac tcttgcatct acctcagggt cgtcaaaaaa accttccggtaacgcttccg 300 cggtgttttc tctcctttcc accacttttt catgtatttc tgctttctcaattgaccctg 360 aatgaggaat tatggggggc cttgggagga ttagtactaa agaaatcgtttgggcagcac 420 actacttgtt acctcccgtg aaagaggaaa ctgagtgctc cttgccctgtgcgtcggaga 480 agcggg 486 140 219 DNA Homo sapiens 140 cacggtctgtacagtttata cacagagata gggacccggc ctgggcccga acccctacaa 60 atatagatcctctctacaaa atagagataa tttagccccc ccatagcagc tgttgggggg 120 ggaaggggagggcacaggag gaagggggag actccagctc ctgccacccc tcacgggtaa 180 cagagggcaggggcagggcc ggcggggaca tgaaggcac 219 141 447 DNA Homo sapiensmisc_feature n=a,t,g or c 141 aacagggcgg ctttttgttt tatttctgtttttttccctt tttcttaaaa aaattaaata 60 aagttctcat tatttcccca atatacatcaaatgagtttt catgcaaagc agcagtcaca 120 gaggcagaac tgtccccagc tcgtgcctctcggcttgaag aaccaccttc tcccggcccc 180 gggttctctg gtgttctcac tgaggatggacgacgcccac tgtctctccc agctggaact 240 ggctatgacg aaacttggct ggcgtagggagaggagtcct cccctctccc caggatgggt 300 ctcaggggac agcaagctct ggggctgatcnccatcattg tccttccatc tgagatccca 360 gtgtgacant tggaaagtcc tcttcccaggaatgcgaggt ccnctctcag tctcaatgga 420 atgggataat gagtgtncac ctataag 447142 210 DNA Homo sapiens 142 aaagtaaagg atttattgta atctgcttac agtcctttgcaaagacagac atatgttttt 60 gcataaagat ataaattgct tcattttaaa ctaatttagtgtttttttaa attatatgaa 120 cttttggtga attatgaact gtaccaaacc aagatttttaagagcaatat ggtacaaaaa 180 taagagcaga cagacaattt ggactgggac 210 143 218DNA Homo sapiens 143 taacaagtaa aaacctgcaa actctttatt aaattctcccatttcatctg tacagaaaaa 60 aatgcacatt atgttcagaa catatctcag taacatctcaaaattacaca gcatgaacat 120 gtaaaaacaa gggaccacca cgattttata catagaaaggaaacccattt acaaaagagg 180 cttgttaatt gtattttttt ctttctttca aaaacaaa 218144 325 DNA Homo sapiens misc_feature n=a,t,g or c 144 ttaaaaatanagtggcttta tttccattgt ttatagtccc cagtatccca tctgataaga 60 accttcaattctataaacaa aaatatttca agaaagtatg ttacacaata gtacatataa 120 gtaatagtttggcagaattt taaactctag tagttcatac ccccaaaaaa caaattttaa 180 aattcaaaaataacagtttt atttaacata tgttacacct taacatttaa aatatcatgc 240 tctaggttaaatatttcatc aacaacactg gtatacaaat aaaatattac ataaaatata 300 tttaagggaaatgttttggg gcttt 325 145 464 DNA Homo sapiens misc_feature n=a,t,g or c145 ggtagganca gaatacttta ataagatacc agtgtcaaaa tacattncct tataaagtta 60agcncccata cagttataat gttgtcagta ggaattcgac aatataataa cgctcatgaa 120atcgttacgt tgacaggtag ggttaatatg aagcttggaa tattttccag tgttttaggt 180aaaactgcca agggntaaaa tgcccttaat gccggggcaa cacacacagg gaaatcaaat 240accaggcatt tacacgtcgt aaacccttca agttctggcc acccgtgtgg ggggtaatgg 300ccgtgcggct taaaatatgg attttacggn aacaccatgg actaggggaa tttccttcat 360agggaacttt aaattttctt tttgganggc tattttctct gtttttgggg gcattaggtc 420ttttccgggg tttnactaan aggttggggg cccntgtggt tttt 464 146 168 DNA Homosapiens 146 tttttttttt tttttttttt tttgaggctc acaaagaggc ctttatttatctagctcaaa 60 gtagacacta tcacaatctt gtttgttact ccttttacta aaatagttcaaatcaatgtt 120 tttaccacac tatcaaaaag ttctatttct tcttgtctcc ccacggtc 168147 301 DNA Homo sapiens misc_feature n=a,t,g or c 147 ccagttccacttttttttta tttaaataac cgaagcaaca gncgtggcac agcagaggga 60 agntgggttggggcgtntga gaggtggcag cagtntggcc tnatgggggg antaggtcac 120 agtgaactccccacacgnct ntcaggttca gcagtcatgg ccataggntt gggagcacta 180 cggaggagccatcagttagt gatgtctctc caagtcccag agaccttagg gacgggagct 240 aagtcagctccctcaagtag cagggccagg ggcatcccag tcagggggtc acggnggccc 300 c 301 148 430DNA Homo sapiens misc_feature n=a,t,g or c 148 ttttttttgt tcaataatagttttatttac ttatttcact gttaacttgg ggataatatt 60 caccacaaag ttgcaggcatcattttatag tacagactac agacgattga ctttttcaag 120 attaaaaatg aacatggtttgtgacacacc tgaaatgcct actgaggaag tgctggccac 180 gaggtaataa aaaaaggtaaaattcagtgc ctttggaaag natgtgggac actgttttag 240 gatgcgagta tggatacatgccctttgctt acaaaggcaa atatacaccc atctgttttt 300 gggactgcgg tttctctatccaccagagga ggcatcttta aatggattca cggacatttc 360 cctgaggagc ttcctggccaggnggaaatc ggcntggtgg tttncaccat cgtggggaag 420 gccctttttt 430 149 278DNA Homo sapiens misc_feature n=a,t,g or c 149 nctanctttc caattttatttagattttat gtgctcacat atagacacac ttaaagagca 60 tacgtttata tatacatatataaaatatag atgatatggg agtttctgac aaagtgattt 120 attaatgaaa attcattcactatataacct ttgaatacca gaggaaactt caatatgtac 180 aaatcaggca tganggttcccagnttctca aactttgggn tatatggaat atggcctcaa 240 ggcaccacaa aagganacattaggtcccta atttaaaa 278 150 249 DNA Homo sapiens misc_feature n=a,t,g orc 150 gatccaaaca atgttttttt ttttttgnta gtttgtgtag taattttact gcataagaaa60 ttacagagat tgcataaatc attaggtcaa cagcatacag agaagaacaa aacaaaacat 120tgtttggatc aaataaaaaa cagcaggaac aactcaattc ttaaaaatac cacgnnttcc 180ccgantgtgg ctccatttgn tagaaanttt tgcattttct ggntaatgtc tgtagttaca 240ttaagcaaa 249 151 299 DNA Homo sapiens 151 tttaaaacac cagtttataatttttttata cattcagttg ttcaacaaat gattctttta 60 atctgcctga agtttcaagtcaacacgtca ctggagaaaa tgtatgaaac tgtagcacta 120 atttctgaaa cgaaggattgaagttcctct ttccaacttc tttcagacca tcactactcc 180 acatgttcct gctcttgtcctggaattagc caccgaatac tctcagttcg aatggtagca 240 tacataataa aactacttaaaaagaataag gaaaatacaa gcaaccagtc cacactttt 299 152 199 DNA Homo sapiensmisc_feature n=a,t,g or c 152 ttttaccagt tctcgatttt atttaggactcaaattaaca ccaaccaaac atatcactaa 60 ctcacttatt tccacatttc caaagttggattgtgctgca aatccataca tttgtgctca 120 ctacacattt ttttaattac attcattgagnggctccaaa gcatcagtcc aataaacatt 180 tttccagccc gaaaaccat 199 153 370DNA Homo sapiens misc_feature n=a,t,g or c 153 aagagtttaa cacaatttattttatgctta aataatcgac taggtcatcc agtgtatggt 60 ttttcataca tatgtcattagagctatgng tcaatgaatg ctgattttat gngaatataa 120 tcaacaaatt aaagantttcaccaaaaccc aaataaaaat gccctttaaa acacagcagc 180 cttattaacc taatatgacactgctagaat ggttacaaat gattggctta ctgaaagggg 240 tctacatctt ntagccagtacacaatacag taataatttt ncagngggct gccattctac 300 tagctaaggg tttctgntcagnccntttta aatacccccg actggggccn tttatgngca 360 ccatncacct 370 154 153DNA Homo sapiens 154 cttgtagctg tctcaaggca tttgtggatg agcccagttccttaaatatg acaaaggcct 60 cccccttcat cttcatggtc tttaaagcca caatgtccaccacatgacca aactgagaaa 120 acagggcata tagggatctc ttcaatctcg tgc 153 155290 DNA Homo sapiens 155 aaacaatttc cttcattaca atttaataca atatttattaactattagtt ttgagaaaat 60 tatttccctc tacatacaaa aatacagatt tgaacactatgaaaaagttc aagacaagta 120 ccatgaaaaa ctggtccttc aaatgaaagg gggaaatttgagggcaatgt gaggttttgc 180 tcgttgtcgg ggacaaatca ttagcagcaa agctttggggccccaaccca ctccatacat 240 acagttttga acccaaaagc caggccagcc aggggacgcccacccagggt 290 156 203 DNA Homo sapiens 156 attgattcag atttattaatttactaattg atcaccctac atttacaggt gttagagtag 60 atatccttaa gaataaacataccttataga aactttaatc agcctgggca acacaatgag 120 accccatctc tacaaaaaatcaaaaatggc tgggcgcagt ggctcacgcc tgtaatccca 180 gcactttggg aggccaaggcagg 203 157 599 DNA Homo sapiens misc_feature n=a,t,g or c 157ntttaagaaa taagaaaatt tattagatgg attatcaagc agtagngaac atttttggga 60gggaaataag aaaaacaagt gtgacctcat actgggttct ggttagaaca cagccactag 120aacaaactcc agtctttttc agtctgttgc tgtacttcag atttaaaatc tgggaatgag 180catgcagcaa tgctccacca gatgaggaag aaaagctgtt aaaaggaact caggatgttg 240ttaggaaggg ggagtggatg ccaggccttc accagactat ccagaagcca ttccatgggg 300tatttggtct gcatactgtg agacactgag ctggttccaa cacagcccct gctgtcacca 360gggtacacag tcaggccaag gaacagccac ggaaatgggg aaaaccaggg ntgagtngga 420gatgtgactt ggggatgtac agggggcttc ggggagcacc agagggagag acttttcctc 480ccagcttttn attgggaatt naggttccag ggtacttngt ttaggggaag acaggtcttc 540ttggnagaga ttgacacctt tnaggatgag gttnaaattc cccacattcc ttcaccaat 599 158182 DNA Homo sapiens misc_feature n=a,t,g or c 158 ctgagtttgt ttattgttctgatttactga aantntaaat attccatcaa attatccagg 60 gaaatccagg tggcagaaatatataatatg ccatttcatc aagaggtctc aaataaattt 120 taaaaggcca gaaaatgatatatatactat gccntttaaa tcacttctnt cttctgtnct 180 ta 182 159 493 DNA Homosapiens misc_feature n=a,t,g or c 159 tttttanaat aaanactata ttttttaaatattttncagt ttatttaaat gtanttncag 60 aactattccn gcataagtta taattcagacatccaaattc aggtaattgc ctcttgggta 120 ataagacaaa taatgatagt ctcaacagaaaaaaagcagc tcattagtat acacacagat 180 tctaatttgc ttcattattt agccatctttgccacaaact acctgctaac agttaaantt 240 ctgacatgga cacgttttag ttgagaagttcanttttgca aagantttaa ttttaaataa 300 ataggantcc aaatatgtcc tgcttcatgttttntttcat aaggcaggat ttngggtttt 360 ttggatactg taaanttttt aaaatgcaaaantgtggnta caggtttcca ggggtnacct 420 ggnatgcctg gngggttctt cccaaagggtaggctggggg nattaggggg ggccccaaag 480 gtccccatgg gnc 493 160 394 DNA Homosapiens misc_feature n=a,t,g or c 160 tttaaattca gtagctttat ttttaaatttcaattagggt cccttggatg aacaagaaac 60 aaagtgtgac attttatgtg gnatctgaaaaccaccctta gnatggcttt acatcggatg 120 catcagtttt ccaaaaagcc agagaactgtgttcccttga agcatttggg gacttcgata 180 gtgccatcta tacactgagc atcctctgtatagctacact tcttttcctt atttttgcag 240 aaggaaagaa actttatcac ccatgtaggcattcccattc cttaaatttt tccctggaat 300 cctttactct ctctccttgg ggacaccacagtgggctttt ttcacagggg acctttacca 360 aggatgcctt taccaanctt gggccntgggcagg 394 161 476 DNA Homo sapiens misc_feature n=a,t,g or c 161tttttttttt gcaggtgact gaaactttaa tgcacctagg gattgaccac aacatttaca 60aatcagtgtt actgcattgg tttttcaaag attagctaca tttataaact ttattttaaa 120agtttcacaa agttaaattt ccttaacact tcaacaggaa tctaactctt tacagtctat 180caaaatggta atattttacc tttttttttt tttttttttt ttttttaaag cactggngct 240cttcttaagt gaaatgttaa cacagggctc aatacataaa agagaaagtg aagttgttcc 300atttgggggg tcccataagg ggcctcatgt ttccctaggn gttacccctt cagacacagc 360acagcctaca aagccatgga attaaaatat taacaatgaa tgcataaaga tttcactgac 420aaataaaaac cagggagtgc attcagtgac cacaactttc taagcttctg cttttc 476 162560 DNA Homo sapiens misc_feature n=a,t,g or c 162 tttgcatttt gacagcccaaattttatttt acaaaccaat gacagctact agaagatgct 60 ttaggaaacc ttagctaagccacataaaca atcagaccta tacaagtaca gaaaaatcta 120 aacatgcttc agaactaaaaaaaaaacaaa aaaaacaaaa aaaacaaaaa aaaaaaccaa 180 gttgtacgtc ctgagggcatacaacttaat ttctacaaaa acatactttt tcaaaagggc 240 tatgagagta tcaattgacaaaagcagaac aagtagcatg attagacaga gaagtcttaa 300 ttgcttaaca caagataaactcagcagttt taaagtgtct gtatccattt taaatgatta 360 gtccaggggt agaaaagatgagggatgggt tccatcatac cttggaaagg gaactccccc 420 tgggggccta aaaccaaacttaccgtccag ggttattaag aatcccaggt tacntaggta 480 aattttttac ncattattttcnatacccag ttcctggcct agggccanaa gaaaatccct 540 gnttggnggc tttanttctt560 163 425 DNA Homo sapiens misc_feature n=a,t,g or c 163 tctgtagacaggatcttgct atgtcgacca ggttggtctt gaactcctga gctcaaacaa 60 tcctctagcatcagcctctg aaagctctgg gattatatgc atgagccacc ttgcccagcc 120 tcaataaattttagttaata ttctttttgt ttttaattaa ttaattttaa aagccagggt 180 ctctctgtcacccagactgg agtgcagtgg tgcaatcagc tcactgcagc cttgaactcc 240 tggacctaagcaatcctccc acttcagcct cctggtgcac accaccatgc ctggctaact 300 aatgtttttactttgtagag atgaggtcta tattgctcag gctcgtcttg aactcctggg 360 cctcatgcgatcttaccact tccancacct aaaagtactg gggattacag atgttgagcc 420 accgc 425 164423 DNA Homo sapiens 164 tgcatttaac attttattga gattctcaac agctgccatttggtttgtat agcaaatttt 60 ttacaaagta acttttttcc atttttgata tttttatgaaaattattttc ttcagtttta 120 aagccctgtc cctcccccaa agaaggatta ataactaccaagtaaggatt atttaggaga 180 aaaacaaaag caaaaacagc tttataaaca cttgtgaaacaggggtaagt gtccgaagtc 240 aagaccttct gggcccagtg gaggtgctgg gctgctccaggacaccatca ccacttcacc 300 atccacaaca tcctcaagag cttgagcagc cctgcacagaccctgggggg gcttcctgtt 360 ccacaagctc cactcccttt ttcctctcca tctttggctgttgggcctcc cctccaaatc 420 tgg 423 165 409 DNA Homo sapiens 165attttggtta gtcataaatt ctgtacttca ttaaagaagt aaatgctttc ttaattttag 60gatgtctgga gccaggattg ttggtcattt gactcatgcc ttgaagcaag gagaatacgg 120tcttgccagt ttttgcaatg gaggaggagg tgcttctgcc atgctaattc agaagctgta 180gacaacctct gctatttaag gagacaaccc tatgtgacca gaaggcctgc tgtaatcagt 240gtgactactg tgggtcagct tatattcaga taagctgttt cattttttat tattttctat 300gttaactttt aaaaatcaaa atgatgaaat cccaaaacat tttgaaatta aaaataaatt 360tcttcttctg cttttttctt ggtaaccttg aaaagtttga tacattttt 409 166 1215 DNAHomo sapiens 166 ctgggaagca gagtgtctgg atggaacctg agctgggtct ctgactcacttctgacttta 60 gttttttcaa gggggaacat ggcaaaggtg ttcagtttca tccttgttaccaccgctctg 120 ataatgggca gggaaatttc ggcgctcgag gactgtgccc aggagcagatgcggctcaga 180 gcccaggtgc gcctgcttga gacccgggtc aaacagcaac aggtcaagatcaagcagctt 240 ttgcaggaga atgaagtcca gttccttgat aaaggagatg aggatactgtcgttgatctt 300 ggaagcaaga ggcagtatgc agattgttca gagattttca atgatgggtataagctcagt 360 ggattttaca aaatcaaacc tctccagagc ccagcagaat tttctgtttattgtgacatg 420 tccgatggag gaggatggac tgtaattcag agacgatctg atggcagtgaaaactttaac 480 agaggatgga aagactatga aaatggcttt ggaaattttg tccaaaaacatggtgaatat 540 tggctgggca ataaaaatct tcacttcttg accactcaag aagactacactttaaaaatc 600 gaccttgcag attttgaaaa aaatagccgt tatgcacaat ataagaatttcaaagttgga 660 gatgaaaaga atttctacga gttgaatatt ggggaatatt ctggaacagctggagattcc 720 cttgcgggga attttcatcc tgaggtgcag tggtgggcta gtcaccaaagaatgaaattc 780 agcacgtggg acagagatca tgacaactat gaagggaact gcgcagaagaagatcagtct 840 ggctggtggt ttaacaggtg tcactctgca aacctgaatg gtgtatactacagcggcccc 900 tacacggcta aaacagacaa tgggattgtc tggtacacct ggcatgggtggtggtattct 960 ctgaaatctg tggttatgaa aattaggcca aatgatttta ttccaaatgtaatttaattg 1020 ctgctgttgg gcttcgtttc tgcaattcag ctttgtttaa agtgatttgaaaaatactca 1080 ttctgaacat atccatgcgc aatcatgata actgttgtga gtagtgcttttcattcttct 1140 cacttgcctt tgttacttaa tgtgctttca gtacagcaga tatgcaatattcaccaaata 1200 aatgtagact gtgtt 1215 167 3269 DNA Homo sapiens 167ggtcgtctcg ggtgaggagg tcgcgccgga agtggctcta gccgtggcgc ttcggcgtag 60taaggagcct gcaacagagt tttgttgttt agggggcgcg gcaccgcacc gctcccttca 120ccttgcagca gccatggcga aaggcagagt cgccgaacga tcgcagttgg gcgctcacca 180cacgaccccc gtgggggacg gggcagcggg gacgcggggt ctcgcggcgc ctggcagcag 240agaccaccag aaggaaaaat cctgggtaga agctggatca gcaagaatgt cactccttat 300attggtgtcc attttcttat ctgcagcttt tgttatgttt ttggtatata aaaattttcc 360tcagcttagt gaagaagaaa gagtgaatat gaaggttccc agagatatgg atgatgccaa 420ggctctagga aaagttttat ccaaatacaa ggacaccttt tatgttcaag tacttgtagc 480ttattttgct acatatattt tcttgcaaac atttgctatt ccaggctcta tatttctcag 540tatactctca gggtttcttt atccctttcc actagcctta tttcttgttt gtttgtgttc 600tggacttggt gcctctttct gttatatgct ttcctattta gttgggagac cagttgtata 660caaataccta acagagaaag cagtaaaatg gtcacagcag gttgaacgtc atagagaaca 720tctcattaac tacattatat ttttgagaat aacaccattt ctgcctaatt ggtttattaa 780tatcacatct cctgtgataa acgtgccatt gaaagttttt tttattggta cttttctagg 840tgttgcacct ccttcttttg tagccattaa ggcaggaaca acactgtatc aacttacaac 900agcaggagaa gctgtttcct ggaactcaat atttattctg atgatcttgg ctgttctttc 960tattctgcca gccatcttcc aaaaaaaact aaagcagaaa tttgagtaaa aataatcatc 1020tgatttttag ttttgctgtc atcaccatct caggattaac agatgcatcc atttatgttt 1080taaaatcacc tcttcagtaa ttaaacaagg aatttgtaaa ataaaatttc ctatcagata 1140gttaaagtaa tacatttaag tgacaagggg agaagaaagt aaaaatggaa attggtatac 1200tgtgaaaagt gctatcaata gttaaggtag acatcttaga catcttataa attattatac 1260caagggtagc tgtagataat agtagtgtgg taggaaattg ttgatccagc taattcattc 1320aatttaattg aatatttttt atctttaata actaaaatag atatttttaa attctagatt 1380ttttaaagta gtgttgcagg ttttgttaat gttaggcttt tttcagagca taaactggaa 1440aacttaaaaa gagatttaca ttttcttcct cttttttttt tttttttttt ctgttttgag 1500acggagtcta gctctgccgc ccaggctgga gtgcagtggc gcgatctccg ctcattgcaa 1560gctccacctc ctgggttcac gccattctcc tgtctcagcc tcctgagtag ctgggactac 1620aggcgcccgc caccatgccc agctaatttt tttgtatttt tagtagagac ggggtttcac 1680cgtgttagcc aggatggtct cgatctcctg acctcgtgat ctgcccgcct tggcctccca 1740aagtgctggg attacaggca tgagccaccg cgcctggccc attttcttcc tcttttgagg 1800taatggattt gtttggagat ggcatgttag tagacgactg aatatggaaa ggatatcgag 1860ttatctattt tgttaatttt atttttgttt tttatcatct agatttttat catggattag 1920tctgaaattt aaagttctgg ccagtcggtt ttctttcatc ttgtagtttt tacagtattt 1980ccactgtgca tatgcaaaat gggtattaca taactgtatc atatttggta ttgataattt 2040tttttttttt tgagacggag tcttgctgtt gcccaggctg gagtggagtg cgtggtgtga 2100tctcggctca ctgcaaactc cgcctcctgg gttcaagcga ttctcctggc ccagcctcct 2160gagtagctgg gattacaggt gtgtgccacc atgcccagct aatttttgtg tttttagtag 2220agacggggtt tcaccatgtt ggccgggctg gtcttgaact cctgacctca ggctatatgc 2280ccacttccac ctcccaaagt gctgggatta caggcatgag ccactgtgcc cagcctggta 2340ttgataattt atattcagat aatttgttat ggctctttaa tatcccacaa ggggctctaa 2400aaagcaaaca ttcaagagta tgtagttttt agacattaag ttaattattt taaacagtga 2460cagcaaaaca caagtgatta aatatagttt atttgttcca atgactaaat tttacctcat 2520ttattaatct ggtcattaag gaatatattt aataatatta tgtaattatt ctttttatgc 2580atgatacacc tagaaaaatg ccttttgttt ctattgatgg ctttgttgtt tggagctact 2640tttgattact tattgcagtt tcccaattta gtctttactt tatctaactc acaaagtaaa 2700attaactgat cacatggcaa ctactgtatt taaatagttc tggaaaaatg aaagtgcttt 2760ttgctgcttg gtaaatgggt aatgcccttg attccttgac tgtaggacat agctgatcta 2820aagtactctg tcagttttac cttcacccat gactgtcatt agttgtcaaa gttgaaaagt 2880actttagctg tgagaaatcc ttgtatgttt ttattataag aggtataatc atcctcaaag 2940cctgttttta ttacatgatg tggactgatt attttttcta tcacagtgtt aacagatgga 3000ttttattgta aatacaaaga aaacatattg attattgtag tattcttatg tcacctggcc 3060ttttgcgtga ggattattta ttatttctag caaggctttc ttcctttctt attgcccaga 3120gactgactga tacatctttt gttattttta cacataaatt aaacatagcc tttttggaca 3180aattcactaa atattaatgt ataaaatgta attgagtaaa tttttatcag aattttaaaa 3240ataaaagagc ttagactcag taggaactc 3269 168 1685 DNA Homo sapiens 168cctgaaaagc cacctcagat tcagccaaca aagattgctg atttgctcct taagcaagag 60attcactgct gctcagcatg gctcagacca actcatgctt catgctgatc tcctgcctga 120tgttcctgtc tctgagccaa ggacaggagg cccatgctga gttgcccaag gcccagatca 180gctgcccaga aggcaccagt gcctaaggct cccactgcta ctactttaat gaagagcatg 240agacctgggt ttatgcagat ctctactgcc agaacatgaa ttcaggtaac ctggtgtctg 300tgctcaccca ggctgagggt gcctttgtgg cttcgctgat taaagagagt ggcaccaagg 360atagcaatgt ctggattggc ctccatgacc cccaccggat cagtctgctg catcttctac 420ctcctgatta tcaggttcca gagggtctga tgtctggcac ctcaagcatc agtttttact 480atattatgat aaaagcaacc tctctataaa tcatataatg taaaggatat caaggttctc 540cataggttct tcgagataag cttaaagctg aatttcctgt gtgtttcagg cattcacaga 600taaactcatt ctctgtactt ctagggtagc atctttatgt atctattatg tacctcttat 660ctattgtgtt atcatctctg ttatagaaga gccttctgta gaccatatag aaaaagatta 720tagaggagga gaatctactg ctggcaattg ggaaccgcaa ggtatactaa ataatatatc 780aacaactaat ggccatctaa tgctatgctg gatatgaact tttggggcct caggaaagaa 840aaaccaggaa ctagtttcaa taatgaggtg tcatggttcc ctgtggcaaa tttagaacac 900ttatcgtttg gcaggacaca gagaggtagg tgaacattcc aggaaagaag cagcttagag 960aaaatgtgga ggaaataata tgacacttag agaaaaagga aggtttattc ttgtcttatg 1020tcttgacctg tttctgagtg cgaacacaaa ccaggtgttt ctgtctcttt ctgagtcacg 1080tctgcccctg ttctggccct tccccatcta gaactgccat tatcagtgga gtagtgggtc 1140cctggtctcc tacaaatcct gggacattgg atccccaagc tgtgccaata ctgcctactg 1200tgctagcctg acttcaagct caggtgagag gcacagaatc cacacactta ttgccatcct 1260ctcctattta tctctgagga tcgaccgggg actgggatag aggaagggtg agctcctcat 1320tcaggaaata gaggagtgtt tcctctttat ttttgctgag tcctgcagcc aggagggtaa 1380tacactctga tcccctcagt ctgaatcttc tcattgtctt ataggattca agaaatggaa 1440ggatgattct tgtaaggaga agttctcctt tgtttgcaag ttcaaatact ggaggcaatt 1500gtaaaatgga cgtctagaat tggtctacca gttactatgg agtaaaagaa ttaaactgga 1560ccatctctct ccatatcaat ctggaccatc tctcctctgc taaatttgca tgactgatct 1620ttagtatctt tacctacctc aatttctgga gccctaaaca ataaaaataa acatgtttcc 1680cccat 1685 169 4441 DNA Homo sapiens 169 ctctgaggag acactttttttttcctccct ccttccctcc tctcctcctc ccttcccttc 60 ccctctcctc ccctctctcctccttccccc ctcggtccgc cggagcctgc tggggcgagc 120 ggttggtatt gcaggcgcttgctctccggg gccgcccggc gggtagctgg cggggggagg 180 aggcaggaac cgcgatggcgcctcagaagc acggcggtgg gggagggggc ggctcggggc 240 ccagcgcggg gtccgggggaggcggcttcg ggggttcggc ggcggtggcg gcggcgacgg 300 cttcgggcgg caaatccggcggcgggagct gtggaggggg tggcagttac tcggcctcct 360 cctcctcctc cgcggcggcagcggcggggg ctgcggtgtt accggtgaag aagccgaaaa 420 tggagcacgt ccaggctgaccacgagcttt tcctccaggc ctttgagaag ccaacacaga 480 tctatagatt tcttcgaactcggaatctca tagcaccaat atttttgcac agaactctta 540 cttacatgtc tcatcgaaactccagaacaa acatcaaaag gaaaacattt aaagttgatg 600 atatgttatc aaaagtagagaaaatgaaag gagagcaaga atctcatagc ttgtcagctc 660 atttgcagct tacgtttactggtttcttcc acaaaaatga taagccatca ccaaactcag 720 aaaatgaaca aaattctgttaccctggaag tcctgcttgt gaaagtttgc cacaaaaaaa 780 gaaaggatgt aagttgtccaataaggcaag ttcccacagg taaaaagcag gtgcctttga 840 ttcctgacct caatcaaacaaaacccggaa atttcccgtc ccttgcagtt tccagtaatg 900 aatttgaacc tagtaacagccatatggtga agtcttactc gttgctattt agagtgactc 960 gtccaggaag aagagagtttaatggaatga ttaatggaga aaccaatgaa aatattgatg 1020 tcaatgaaga gcttccagccagaagaaaac gaaatcgtga ggatggggaa aagacatttg 1080 ttgcacaaat gacagtatttgataaaaaca ggcgcttaca gcttttagat ggggaatatg 1140 aagtagccat gcaggaaatggaagaatgtc caataagcaa gaaaagagca acatgggaga 1200 ctattcttga tgggaagaggctgcctccat tcgaaacatt ttctcaggga cctacgttgc 1260 agttcactct tcgttggacaggagagacca atgataaatc tacggctcct attgccaaac 1320 ctcttgccac tagaaattcagagagtctcc atcaggaaaa caagcctggt tcagttaaac 1380 ctactcaaac tattgctgttaaagaatcat tgactacaga tctacaaaca agaaaagaaa 1440 aggatactcc aaatgaaaaccgacaaaaat taagaatatt ttatcagttt ctctataaca 1500 acaatacaag gcaacaaactgaagcaagag atgacctgca ttgcccttgg tgtactctga 1560 actgccgcaa actttatagtttactcaagc atcttaaact ctgccatagc agatttatct 1620 tcaactatgt ttatcatccaaaaggtgcta ggatagatgt ttctatcaat gagtgttatg 1680 atggctccta tgcaggaaatcctcaggata ttcatcgcca acctggattt gcttttagtc 1740 gcaacggacc agttaagagaacacctatca cacatattct tgtgtgcagg ccaaaacgaa 1800 caaaagcaag catgtctgaatttcttgaat ctgaagatgg ggaagtagaa cagcaaagaa 1860 catatagtag tggccacaatcgtctgtatt tccatagtga tacctgctta cctctccgtc 1920 cacaagaaat ggaagtagatagtgaagatg aaaaggatcc tgaatggcta agagaaaaaa 1980 ccattacaca aattgaagagttttctgatg ttaatgaagg agagaaagaa gtgatgaaac 2040 tctggaatct ccatgtcatgaagcatgggt ttattgctga caatcaaatg aatcatgcct 2100 gtatgctgtt tgtagaaaattatggacaga aaataattaa gaagaattta tgtcgaaact 2160 tcatgcttca tctagtcagcatgcatgact ttaatcttat tagcataatg tcaatagata 2220 aagctgttac caagctccgtgaaatgcagc aaaaattaga aaagggggaa tctgcttccc 2280 ctgcaaacga agaaataactgaagaacaaa atgggacagc aaatggattt agtgaaatta 2340 actcaaaaga gaaagctttggaaacagata gtgtctcagg ggtttcaaaa cagagcaaaa 2400 aacaaaaact ctgaaaagctctaaccccat gttatggaca aacactgaaa ttacatttta 2460 gggaattcat cctctaagaattatgttttt gtttttaatc atatgttcca aacaggcact 2520 gttagatgaa gtaaatgatttcaacaagga tatttgtatc agggttctac ttcacttcat 2580 tatgcagcat tacatgtatatcacttttat tgatgtcatt aaaacattct gtactttaag 2640 catgaaaagc aatatttcaaagtattttta aactcaacaa atgtcatcaa atatgttgaa 2700 ttgatctaga aattatttcatatataaatc agaatttttt tgcatttatg aacggctgtt 2760 tttctacttt gtaattgtgagacattttct tggggaggga aaattggaat ggttcccttt 2820 tttagaaatt gaagtggtcttcatatgtca actacagaaa aggaaaaaaa tagaaattga 2880 aggattttta tgaaattatattgcattact atttgcagtc aaactttgat ccttgttttt 2940 gaaatcattt gtcaattcggaatgaaaaat tataatgtaa ttttacatta cataagttcc 3000 ttttacaatt aaaaaatagcacttcttcat cttatgcctg tttgagaaga tattaaattt 3060 tcacattgtt gacagtgaaatgctatgttg gtttataaga ttacagacca tttgttttca 3120 tgtggataat tttagtgcattgctcacccg gtatgttttt tttttttaac ttgaacattt 3180 tgcttgtttt gtttttcttttttaattaga taatcacacg gaaaattaag ctgttcatat 3240 ctttaaatta ggattgcaaaccaaggaaag aacgcatttg agattttaag atgtcactta 3300 taaggggaga agtgttcttaaaaagtcaac cagaaaactg ttatgccttt tatttgtttg 3360 caaggatgtc tttgtaatgtgtttcatgaa tagaatatcc aatagagata agctgacttg 3420 aatcattttg agcaattttgccctgtgtta tatgtgtttc acgcacatat ttgcagttgg 3480 attttctcca acagaaagtggattcactac tggcacatta acaagcacca ataggttttt 3540 attccaactc cgagcactgtggttgagtaa catcacctca attttttatt atccttaaag 3600 atattgcatt ttcatattctttatttataa aggatcaatg ctgctgtaaa tacaggtatt 3660 tttaatttta aaatttcattccaccaccat cagatgcagt tccctatttt gtttaatgaa 3720 gggatatata agctttctaatggtgtcttc agaaatttat aaaatgtaaa tactgatttg 3780 actggtcttt aagatgtgtttaactgtgag gctatttaac gaatagtgtg gatgtgattt 3840 gtcatccagt attaagttcttagtcattga tttttgtgtt taaaaaaaaa taggaaagag 3900 ggaaactgca gctttcattacagattcctt gattggtaag ctctccaaat gatgagttct 3960 agtaaactct gatttttgcctctggatagt agatctcgag cgtttatctc gggctttaat 4020 ttgctaaagc tgtgcacatatgtaaaaaaa aaaaaaaaaa gattatttta ggggagatgt 4080 aggtgtagaa ttattgcttatgtcatttct taagcagtta tgctcttaat gcttaaaaga 4140 aggctagcat tgtttgcacaaaaagttggt gattcccacc ccaaatagta ataaaattac 4200 ttctgttgag taaactttttatgtcatcgt aaaagctgga aaaatccctt tgtttctatt 4260 tataaaaaaa gtgcttttctatatgtaccc ttgataacag attttgaaga aatcctgtaa 4320 gatgataaag catttgaatggtacagtaga tgtaaaaaaa attcagttta aaagaacatt 4380 tgtttttaca ttaaatgtttatttgaaatc aaatgatttt gtacataaag ttcaataata 4440 t 4441 170 5559 DNAHomo sapiens 170 ggctggcatt gcagtgcggg ccgtgcgggc tgcgcgggcg cggggaggcgcgggcggcaa 60 actgcgggca cccggcaccc cgcagccagt accgggcgga ggcgtcagagccgcgcaccg 120 cggacgagca ggcccaggca tccagtaccc tgctgactct gacatgcccccagcctcccc 180 cagctctgca gggagccctg gtgccagaga ccttctccca tttctccctatgggtgcctg 240 acctgagggc agagacatct gagtgtgtat aagcacagca ggacaccaggacctggcctg 300 aagacatttc ctctcctccc ctctggattt ctcagagact gttctgcgatgaccacagca 360 aggtaccggc ccacctggga cctggccctc gacccgctgg tgtcttgcaagctctgtctt 420 ggggagtacc cagtggagca gatgacaacc atagcccagt gccaatgcatcttctgtact 480 ctgtgcctga aacagtatgt tgagctcttg atcaaagaag gattagaaaccgcaattagc 540 tgcccagatg ctgcctgccc taaacagggc cacctacagg agaacgagattgagtgcatg 600 gttgcagctg aaattatgca aagatataaa aagctacaat ttgaaagagaggtgctgttt 660 gatccctgtc ggacttggtg cccggcgtcc acctgccaag ctgtgtgtcagctccaggac 720 gtggggctgc agacccccca gccagtgcag tgcaaagcct gccgtatggaattctgctcc 780 acctgcaaag ccagctggca ccctggccag ggctgcccgg agaccatgccgatcaccttc 840 ctccccgggg agaccagtgc tgctttcaaa atggaagaag atgacgcgcccatcaagcgc 900 tgccccaagt gcaaagtcta catcgagcga gacgaaggct gcgcgcagatgatgtgcaag 960 aactgcaagc acgccttctg ctggtactgc ctggagtctc tggacgatgatttccttctg 1020 atacactacg ataagggacc ctgccggaac aagctgggcc actcccgggcatctgtgatc 1080 tggcatcgga cacaggttgt gggcattttt gcaggatttg ggctgctgctcttggtggcc 1140 tcacctttcc tactcctggc cactcccttt gtactttgct gcaagtgcaagtgcagtaaa 1200 ggtgacgacg acccgttacc cacctagagg aagcgcgatg ctggaacacatccctgcctc 1260 cgggaagtgt ggctctcccc caaccctccc caccgtcccc ccttcactaaacatctttct 1320 tgccttatgt gccccattga gcttcacagt gtcaggctgg acgccgtgatttcagggacc 1380 tatgtcacaa tgttcgctga ggccccaggt gtggtgggga ggggaggcaggtgtgggtag 1440 cgcacatccc cacagatcaa tctctgcaga tgacagggag gtgctgtgagaagtgcacca 1500 ggcagctttc tctctgtggt agactaggca tgtctgggga tggcctaagagactttctgc 1560 tccttggctt ctagatggca ccatgttgtc agagaagtct tttaaggactgccactctct 1620 tcagacagaa tctgattatt ccagcttgag agaagcactc tgtttatgacaactgttttt 1680 attactaatg gcatttagta aaatcctttt tagaaggtat tttttttccaactgagtagt 1740 gaaaatcaac aaggtgcata taaaccatcc tatgcctttc ttgaaatgtgcattttaaga 1800 agttatagtt aaacgacttt tcaggagatt tagaaagcct tatgcactctttgtgttttt 1860 cttgaaactt gctgtagtaa ctttttgaac gctgtaagct gtgtactgttataagtgtgc 1920 ttcctatatt gttgcatttc cttgataata ttgacgtgtt taaaggaacatctcatctcc 1980 attagatttg ccttttgttg ttttctctct ttggtgattc agctcagctcatgggcctca 2040 tcccttctct cccaggtagc agaaaacgct ttttattgca ttcaatcccactgctttgct 2100 cggcaatggt tctcctccga attgctgccg tctggcctct ggcctcagtcttcagataga 2160 cagtaagaag aaagcagcct cattgatccg cagatgtagg ggcctcttggcagaggctgg 2220 aggactctgg gggctaggga agagcctgcc agattttcac atttttaaaatgttctagtc 2280 attttgagaa atcatatatc ttacacagtt ccaagtcctg ttgctaaccgttttgctctt 2340 gttggggaaa agaacctccc atttcacttc gttttaacgt ggggattttaccacttgatc 2400 ttttacaggg ctgtctgtga ccatttccat ggcagcagga tgcagggattaataaggaca 2460 catacacatt attccaccaa ttgactttga aaagtggaga aagtgtattctttaaagaga 2520 atttacttct aaaagccaca ggtgctttta caaagcaaac tgcattgaatttaaaacttc 2580 taaaaataac aggcaaatat tgtagctata ttacagtggg attttaaaaatcttgttaaa 2640 cattctataa agaagtaaaa caaaatcctt ttatctcagt tatttgcccatcacaagcac 2700 atttttaaaa tgttgctttg tgtgtgtttg acttctgcat ttgagtatcagtctcaggtc 2760 ctagtttact ttccctggtt ggaaatttat ttcttatttc ctaacattgaattcgttaga 2820 aaaaacagcg tcacctcact cttcacctgt catgttgatt ttccttatgaacccgaagcc 2880 atttagaaaa tccctgtgtg tcaaaattac attcaaaaag ctctccttgtaattgcaagt 2940 ttagtaactc agtaagaaca tgcctgcgac tccctttctg gatggaacctgggctgtggc 3000 tctctgtcgt ttgtggtgct gtgatggtgt ctactgttag aatagcttttctggaggtgg 3060 gtggcaactc cacgcgggag tcattggctg ggcttgagcc ctcagcctgtgatatgtgga 3120 tgcagctgtc cagccactgc cctttaacat gcccagcaca catgggaggcctgtggccct 3180 gtgcccagtg gcccacagga cacgcctcca ccatatgctc atccttcctgcctgaaattg 3240 ctgctgccca tcgcatgagc ccacacagta gcacccccgt ccttaggatgagagtcagag 3300 cctttggaaa ggctgcatcc ccagggctag agctcagatg accttatttctagagggaca 3360 ggctgttctg ttggaagagt ctctggccca gtcatgcaca tctgtagccccagccatcct 3420 tgtgccttca cctctgatgt gtttcacaag cacgtagttc aacccagatagggaccacag 3480 agattctggg gccagccagg ggcagtcaaa ttagcaccta ctggctctgactttttgtat 3540 gaagcatgcc tcagtttcct cattttgatc tagatataaa attaaaattgtccatttcct 3600 atataaatac cagcaagatc actctgagat acataaactc gcatttccttctgttttagt 3660 aaggagtgcc agacttatct ttgatgggaa tacagtatga accctgcttgatgtaaaatg 3720 gaaatagcac acaggcagat ggccctgggt ttggactttg atcttgccatcattccccag 3780 taaaacctgg ggagttctgc gttgagtgga cggacttatt cctgtgaagcggcataattt 3840 gtctccattg aaaaatggca ttcactctta cagatggtgt tcactgcaagccccagaagc 3900 atatggcatg tgttcactaa gaggccttta atcctgggga gtaaggggcgaaggccctta 3960 gacaaccatg gctgctgtac cgccgcccag ggtgggtggc cagtgaggactggccttagc 4020 ccagtggacc tgtggcttct ctgaggccct tgagtaactg accacatttggaggttttgc 4080 tggaaatgcc tgacctctca gtctggctct gctgtgtagt ccatagcccagccagatgag 4140 cttgcagcct cataggaggt cagcaccttg caaagatgca gtcaccatagatgtccacgt 4200 agcagagact gacttaggat ctgagataaa gcatcggatt gcaggaataactgtccaaat 4260 tagttcttcc tcctcaactc ataggagtag ctgtggacag aggaaccaacatctgccacc 4320 tctggcattt tctttctttt ttttcttttt gagacggagt ttcgcttttgtcccccaagc 4380 tggagtacaa tgacaggatc tcggctcact gcaagctctg cctcccgggttcaagcgatt 4440 ctcctgcctc agcctcccaa gtagctggga ttacaggcac ccaccacctcacccagctaa 4500 tttttgtatt ttcagtagag acggggtttc accatgttgg ccaggctactctcaaactcc 4560 tgacctcagg tgatctgccc acctcggctt cccaaagtgc tggaattacaggcctgagcc 4620 accccacccg gcctattttc ttaaagggga acaaatgatc ttgacaacatattattccat 4680 aaaaccagtt tagggcacag gccagttcct gattagaaca caggacctgtgggagggact 4740 atcagagatg caaaaattac ttcaagatga gtttattgtt ttcatttgtattgcaaaagt 4800 tagaagtcat tttacaaatt aaaaaaacat ttttttcttg gtagtctttaaaaattaggg 4860 gattgaaagg atccaggatg ggctttgtgt gtgtgtctca gattctcatttattagtgag 4920 cacacctgtg tatatatata aatcacaagg agatcatcaa gggaaaacattttgcatgtg 4980 taaagcttca tgaagttctc tttaaaaaat accaaagctt gtttatttctgataattaac 5040 ctaagccctt atgaaaataa acaaaatgaa gggattatga caggtattaccaaaaacacc 5100 aaaaggaaca aaggggcctg cgttaaaacc taattgctaa tgcttcacaactaggagagc 5160 atgccgtctt gatgtttaaa aaacccaggg tctccaccct tcctttgatttgtgcaattc 5220 tgtcttccac agttccggag ccttcagtga ggggtagcta catgccccatgcctgccctt 5280 tctttccttc tttgctcact ttactatggg tgtattttaa tcttgtataaaaatatgcat 5340 gaatgagtca tgcacatgta tacgttatgt atttgacaag tggtggtgaaacaaaatcaa 5400 aacagatttg atttgtgttt ttgaaatgtc agtacatttt gtgccactaacactgtgatg 5460 tataaaagag ctgtttgaat gccttttaat gttgtgtttt gtactctggaatcatatgga 5520 aaaagtttga tttgtaattt caatacatat tttaaatgt 5559 171 6504DNA Homo sapiens 171 ataaagactt caaatggaaa ttagatgcaa tattgaaaaacgtgcccaat ttgttacaca 60 tggagtccag caagctaaaa gtacagaagg tggagccctggaacagcgtg cgtgtgacat 120 tcaacatccc ccgggaagca gcggagcggc tacggatccttgctcagagc aacaaccagc 180 agcttcggga tttagggatt ctctccgttc agattgaaggggaaggtgct attaacctgg 240 ctttggctca gaaccgaagc caagatgtga gaatgaatggacccatggga gctggaaatt 300 cagttaggat ggaggcggga tttcctatgg caagtggtccaggaataata aggatgaaca 360 accctgccac tgttatgata cccccgggtg gaaatgtgtcatcttccatg atggcaccag 420 gccccaatcc agagctgcag cccaggactc ctcgccctgcttctcagtca gatgcaatgg 480 atccactcct ctctgggctc catatacagc agcaaagtcatccctcagga tctttagctc 540 ccccacatca cccaatgcag cctgtctctg tgaacagacaaatgaaccca gctaattttc 600 cccagctgca gcagcagcag caacaacaac aacagcagcagcagcagcag cagcagcaac 660 aacagcaaca gcagcaacaa cagttgcagg caagacccccacagcaacat cagcagcaac 720 agccacaggg aattcgaccc cagtttactg ccccaactcaggtgcctgtt cctccaggct 780 ggaaccagct gccttctgga gcccttcaac ctcctccagcccagggttct ctgggcacaa 840 tgactgcaaa ccaagggtgg aagaaggctc ccttgcccggcccaatgcaa cagcaactcc 900 aggcaagacc atccttagcc acggtacaga cgccttcccaccctccccct ccatatccct 960 ttggcagcca gcaagcctca caagcccaca caaactttcctcagatgagc aacccaggcc 1020 agttcacagc tcctcagatg aagagtttgc agggagggccctctagggtc ccaactccct 1080 tgcagcagcc ccacctcacc aacaagtctc ctgcctcctcaccctcctcc ttccagcagg 1140 gatcccctgc atcctcccca acggttaacc aaactcagcagcagatggga ccaaggccac 1200 ctcaaaataa cccacttccc cagggatttc agcagcctgtcagctctccg ggtcggaatc 1260 ctatggttca acagggaaat gtgccaccta acttcatggtgatgcagcag caaccaccaa 1320 accaggggcc acagagttta catccaggcc taggaggaatgcctaaacgc ctcccacctg 1380 gcttctcagc aggacaggcc aatccgaact ttatgcaaggtcaggtgcct tcgaccacag 1440 caaccacccc tgggaattca ggagcccctc agctgcaagcaaatcaaaat gtccagcatg 1500 caggtggtca aggagctggt cctcctcaaa accagatgcaggtgtcccac gggccgccaa 1560 atatgatgca gcccagcctc atgggaattc atggcaacatgaacaatcag caggctggta 1620 cttctggggt tcctcaagtg aacctcagca acatgcaaggccagccccag cagggcccac 1680 catctcagct gatgggcatg caccagcaaa tcgtgccctcccagggccag atggtccagc 1740 aacaaggaac cttgaaccct cagaacccta tgatcctttcaagggcccag cttatgccac 1800 agggccagat gatggtgaac cccccgagcc aaaatcttgggccctcgccc caaaggatga 1860 ccccacccaa gcagatgctt tcccagcagg gcccacaaatgatggcgcca cataaccaga 1920 tgatggggcc tcaggggcag gttttgctcc aacagaacccaatgatagag cagattatga 1980 ccaatcaaat gcaggggaat aagcagcagt ttaacactcagaaccagtcc aatgtcatgc 2040 cgggaccagc ccagataatg aggggaccaa ctccgaacatgcaaggaaat atggtgcagt 2100 ttacgggaca gatgtcagga cagatgctgc cccagcaagggcctgtgaac aacagtccat 2160 ctcaggttat gggcattcag ggacaggtcc tgcggccaccagggcccagc ccacacatgg 2220 cccagcagca tggtgatcct gctactacag caaataacgatgtcagttta tctcagatga 2280 tgcctgatgt tagcattcaa caaaccaaca tggtcccccctcatgtgcag gccatgcagg 2340 gaaacagtgc ctcgggaaac cacttctcag gccatgggatgtctttcaat gcacctttca 2400 gtggagctcc caatggaaat cagatgtcct gtggtcaaaatccaggcttc ccagtcaata 2460 aggatgtcac gctaacgagc ccattgttgg tcaacttattgcagagtgac atatctgcag 2520 gccattttgg ggtaaacaat aagcaaaata ataccaacgcaaataaaccg aagaagaaga 2580 aaccccctcg gaagaagaaa aatagtcagc aagatctaaacaccccagat actcgcccag 2640 ctggtctgga agaggctgat cagccaccgt tgcctggagaacaaggaatt agcttggata 2700 actcaggccc taaactgcca gaattttcaa accggccaccaggttatcct tctcaaccag 2760 ttgaacagag gccacttcag cagatgcctc ctcaactcatgcagcatgtg gcacccccac 2820 cacagccacc acagcagcag ccacagccac aactgcctcagcagcagcag ccaccacctc 2880 ccagtcagcc acagtctcag cagcagcagc agcagcagcaacaaatgatg atgatgctca 2940 tgatgcagca ggatcccaaa tcagttaggc ttccagtctctcaaaatgtc catcctccaa 3000 ggggccccct gaaccccgac tcccagagaa tgcccatgcaacagagtggc agtgtgcctg 3060 tcatggtcag tctgcaagga cctgcctccg tgccaccatcacctgataaa caaagaatgc 3120 caatgcctgt gaatactccc ttgggaagca attcaaggaaaatggtctat caggagagcc 3180 cgcagaatcc ttccagctcg ccactggcgg agatggcctcactccctgaa gcaagtggca 3240 gtgaagcacc atctgtccca ggaggcccaa acaacatgccttcacatgta gtacttcccc 3300 agaatcagtt aatgatgaca gggccaaaac ctggaccatcgcccctttca gcaactcaag 3360 gtgcaactcc ccagcaaccc cctgtaaatt ccctgcccagctctcacggc caccacttcc 3420 caaatgtggc tgcgccaacc cagacatcta ggcccaaaacaccaaacaga gccagcccca 3480 gaccctatta tcctcagaca cccaacaacc gccctcccagcacagaacct tcagaaatca 3540 gtctgtcacc agaaagactc aatgcctcca tagcaggactcttccctcca cagattaata 3600 ttcctttacc tcctaggcca aatttaaaca ggggctttgatcaacaaggc ctaaatccaa 3660 caactttgaa ggccatcggg caagcacctt caaatcttaccatgaatcct tccaattttg 3720 ctaccccaca aactcacaaa ttagattctg tggtagtgaattctggaaag cagtctaatt 3780 ctggagcaac aaaacgggca agtccaagca acagtcgcaggtctagtcct gggtccagta 3840 ggaaaaccac tccaagccct gggaggcaaa attcaaaagcccctaaactt actctggcct 3900 ctcagacaaa tgcagcccta ttgcagaatg tggagttgccgagaaatgta ttggtcagtc 3960 ccactcctct ggccaatccc cctgtacctg ggagctttcctaacaacagt gggctgaatc 4020 ctcagaattc tactgtgtct gtggctgcag ttgggggtgttgttgaggat aacaaggaga 4080 gcttgaatgt gcctcaggac agtgattgcc agaattcccagagtaggaag gaacaggtaa 4140 acattgaact aaaagcagtc cctgcccaag aagttaaaatggttgtccct gaagatcagt 4200 ccaaaaagga tgggcagcct tcggatccta acaaacttcccagtgtcgaa gagaacaaaa 4260 atttggtgtc tcctgctatg agggaagcac caacatcgttaagtcaactt cttgacaact 4320 ctggagctcc caatgtgaca attaaacccc ctgggcttacagatctggaa gtaacacctc 4380 cagtagtttc tggggaggac ctcaaaaaag catctgtcattcccacactg caggatctgt 4440 cttcttctaa agaaccttct aattccctaa acttacctcacagtaatgag ctgtgttcat 4500 cccttgtgca tcccgaattg agtgaggtca gttctaacgttgcaccaagc atccctccag 4560 taatgtcaag acctgttagc tcttcctcca tttccactcccttgccccca aatcaaataa 4620 ctgtatttgt cacttccaat cccatcacaa cttcagctaacacatcagca gctttgccaa 4680 ctcacttgca gtctgcattg atgtcaacag ttgtcacaatgcccaatgcg ggtagcaagg 4740 ttatggtttc tgagggacag tcagctgctc agtctaatgcccggcctcag ttcattacac 4800 ctgtctttat caattcatcc tcaataattc aggttatgaaaggatcacag ccaagcacaa 4860 ttcctgcagc cccactgaca accaactctg gcctgatgcctccctctgtt gcagttgttg 4920 gccctttaca catacctcag aacataaaat tttcttctgctcctgtaccg cctaatgccc 4980 tctccagtag tcctgctcca aacatccaga caggtcgacctttggtcctt agctcacgag 5040 ccacccctgt tcagcttcct tcccctcctt gtacgtcttctccagttgtc ccttctcatc 5100 cccctgtgca gcaagtgaaa gaattgaatc cagatgaggctagccctcag gtgaacacct 5160 cagcagatca gaacactctt ccctcttcac agtcaaccacaatggtttct ccccttttga 5220 ccaatagtcc agggtcctct ggcaaccggc gaagcccagtctcgtctagt aagggcaaag 5280 gaaaagtgga caaaattggc caaattttgt tgaccaaggcatgtaagaaa gttacaggct 5340 ctcttgagaa aggggaagaa caatatggtg cagatggagagactgaaggc caagggctag 5400 acaccacagc tccggggctc atgggaacag agcagttatccacagagctg gacagtaaaa 5460 ccccaacgcc cccagcaccc actctgctaa aaatgacctctagccctgtg ggcccgggca 5520 ctgcctcagc aggacccagc ttacctggcg gtgctctccccaccagtgta cgctcgatag 5580 taaccactct ggtaccctcc gagctcatct ccgccgtaccgaccacaaaa agcaatcatg 5640 gtggcatagc atctgagtca cttgcgggtg gcctagtggaggagaaggtg ggatcccatc 5700 cagaacttct acccagcata gccccgtcgc agaatttagtctcaaaggaa acttcaacca 5760 cagcactgca ggcctctgtt gccagaccag agctggaggtaaatgctgcc atagtctctg 5820 gacaaagcag tgagcccaaa gagatagttg aaaagtccaaaatcccaggc cgaagaaact 5880 cccgaactga agagccaact gtggcctctg aaagtgtggaaaatggacat cgtaaacgat 5940 cttctcgacc tgcttcagcc tccagctcta ctaaagacataaccagtgcg gtgcaatcca 6000 agcgaagaaa atccaagtaa acaagcagga ctgcgacttgatacttggaa atgtgtgtga 6060 cttttacaaa gagcaatttt gagctgtgac ttttttaaatcaatttctgt acagttagta 6120 attttaataa tgtggccctt ttcctagtcc ctgcaacctgtttcataaag tgcaatgggg 6180 aaagcaggac tgttgagccc ttttggtgtt gcgagttgaagttcaaggtt tctaaaatgt 6240 tgtcttgtat tgaaaggagc taatgccatt ataaatgttactagttttca catttcctaa 6300 gcagcctaga gtacagggtg agcattttta gatctcctaatgtattgtgc cgtggaagta 6360 ctgtgtgtga atagcagtag tgggggcaaa agcaatcttctcatttggaa atgttgtaaa 6420 taattttatt atatagtgtt ttggatgtat ttgttgtagaaatggaccag tgaataaaga 6480 gaatctaagg atttgtacaa tgtg 6504 172 6571 DNAHomo sapiens 172 ggcatgcgtg cagctctttg gaggcggtag ctttttcggc gtcgagactggaggctgagt 60 gctaaactgt gtggggcgcg gatgggatcc agctgttagt cgggtaggcatagctttgtg 120 ttattcttgg aaaatttcgc accacttgtg aattccttga acctgggcattgcaaaccca 180 cttctgttgg gcccatctcc tttgcacttt gctcagatta agactcagttggcgcttcag 240 cagctgaatg ccgttgcctc acatggttca acaccacctt atactttattaaatcaggct 300 ttcttgaaaa tagccatgtc gagacccagg tttaatcctc gaggagactttccacttcaa 360 aggccacgag cacctaaccc ttctgggatg aggcctccag gaccatttatgaggcctgga 420 tctatgggtc tcccaagatt ttacccagca gggagagcac gtggaattccacacagattt 480 gctggcctgg aatcttatca gaacatgggg ccacagagaa tgaatgttcaggtaactcaa 540 cacagaactg atccaagatt gaccaaagaa aaactggatt ttcatgaagcacaacagaag 600 aaggggaagc ctcatggtag ccggtgggat gatgagcctc atatatctgcatcagtggca 660 gtgaaacaga gttctgtaac acaggttaca gagcagagtc ccaaagtacagagccgctat 720 acaaaagaga gtgcctcaag tatcttagca agttttggat tatctaatgaagacctagaa 780 gaacttagtc gctatcctga tgaacaacta actcctgaaa atatgccattaattttgagg 840 gatataagaa tgcgaaaaat ggggcgccga ttacctaatt taccttctcagagcagaaat 900 aaagaaacac ttggtagtga agcagtttca agtaatgtga tcgattatgggcatgcaagc 960 aaatatggct acacagaaga tccacttgaa gtacgtattt atgatcctgaaattccaact 1020 gatgaggtcg agaatgaatt tcagtcacag cagaacattt ctgcatctgttcccaatcca 1080 aatgtgatat gtaattctat gtttcctgtt gaagacgtat ttcgccaaatggacttcccc 1140 ggtgagtcct ccaataatcg gtcctttttc tcagttgaga gtggaaccaagatgtcaggc 1200 ttacacattt caggaggaca gtcagtcctt gaacccataa aatccgtcaaccaatccatt 1260 aaccaaacag ttagccagac aatgagtcaa tctctgattc ctccatctatgaaccagcaa 1320 cctttttcgt cggaattaat ttcatctgta agccagcaag agcggatcccacatgaacct 1380 gtgattaatt catctaacgt acatgttgga tcaagaggaa gtaaaaagaattaccagtca 1440 caggctgaca ttcccattcg gtctcccttt ggtattgtga aagcatcctggctaccaaag 1500 ttttcacatg ctgatgccca gaagatgaag agacttccaa ctccttctatgatgaatgat 1560 tattatgcag catctccaag aatatttcca catttgtgtt ctctgtgtaacgtagaatgt 1620 agtcatttga aggattggat tcagcatcaa aatacatcta ctcatattgagagctgtcga 1680 cagttacgtc aacagtatcc tgattggaat cctgagatcc tcccatcgagaagaaatgag 1740 ggcaatagaa aagaaaatga aactccacga agacgttctc attcccccagtcctaggcgt 1800 tctagaagat caagctcaag tcacagattc cgtcggtctc gaagcccaatgcattacatg 1860 tataggccga gaagtcgaag tccaagaatt tgccatcgtt tcatttctagatacagatcc 1920 agatccagat cccgttcacc atatcgaatt agaaatccat ttagaggtagtccaaaatgc 1980 tttcgatcag ttagccctga gaggatgtca aggagatcag tgagatcatcagatagaaaa 2040 aaagcattag aagatgtagt acaacgatct gggcatggga cagaatttaataaacagaag 2100 catcttgaag ctgctgataa gggacattca ccagcacaaa agcctaaaactagcagtgga 2160 acaaaaccat cagttaaacc tacaagcgct acaaagagtg attcaaatctaggaggacat 2220 tctattcgtt gtaaatcaaa gaatcttgaa gatgacactt tgtcagaatgtaaacaggtg 2280 tctgataaag ctgtttctct ccagcgaaag cttcggaaag aacagtcattgcattatggt 2340 tcggttcttc ttataactga attaccagag gatggttgta ctgaagaagatgtgagaaaa 2400 ttatttcaac catttgggaa agtgaatgat gtcctaattg ttccatatagaaaagaggct 2460 tacctagaaa tggaatttaa agaggcaatt actgcaatta tgaagtacattgaaacaaca 2520 cctcttacga taaaaggaaa aagtgtgaaa atatgtgttc caggaaagaaaaaagcacag 2580 aacaaagagg tgaagaaaaa gactttagag tcaaagaaag tatctgcatctaccttaaaa 2640 agagatgcag atgcttcaaa agctgttgaa attgttactt caacttctgctgccaaaact 2700 ggacaagcca aggcatgtgt agccaaagta aacaaatcta cagggaaatcagcaagttct 2760 gtaaaatctg tggtaacggt agctgttaaa ggtaataaag cttcaatcaaaacagcaaaa 2820 tctggtggaa agaagtctct agaagccaaa aagactggga atgtcaaaaacaaagactct 2880 aacaaacctg tgactatacc agaaaactct gaaataaaga ccagtattgaagtcaaagcc 2940 actgaaaact gtgctaaaga agctatttct gatgctgctt tggaggccacagagaatgaa 3000 ccacttaaca aggaaacaga agaaatgtgt gtgatgcttg tctctaatttgcctaataaa 3060 ggatattctg tagaagaagt ttatgactta gcaaaaccat ttggtggtttaaaggatatc 3120 ttgattttat catctcataa aaaggcatat atagaaataa atagaaaagctgctgagtct 3180 atggtaaaat tttatacctg cttcccagta ttgatggatg gaaatcaactctcaataagt 3240 atggctcctg aaaacatgaa tataaaagat gaggaagcta tatttataaccttggtaaaa 3300 gaaaatgacc cagaggcaaa catagataca atttatgatc gatttgtacatcttgataat 3360 ttaccggaag atggacttca gtgtgtactt tgtgttggac ttcagtttggaaaagtggat 3420 caccatgtat tcataagtaa tagaaacaag gcaattcttc agttagatagtcctgaatct 3480 gctcagtcaa tgtatagctt tctgaaacaa aatccacaaa atattggtgaccatatgttg 3540 acctgctcat tatctccaaa gatagactta ccagaggtgc aaattgagcatgacccagaa 3600 ttagaaaaag aaagccctgg cttgaaaaac agtccaattg atgaaagtgaggtgcaaaca 3660 gcaactgata gtccctctgt taaacctaat gagcttgaag aagaaagtactcccagcatt 3720 caaacagaaa ctttggtaca gcaggaagag ccttgtgagg aagaagctgaaaaagcaaca 3780 tgtgattctg actttgctgt tgaaactttg gagcttgaaa ctcaaggagaggaggtcaaa 3840 gaagaaattc ctcttgtagc atccgcttca gtcagtattg aacaattcactgaaaatgcc 3900 gaggagtgtg ctttaaatca gcagatgttt aacagtgact tggagaagaaaggggcagaa 3960 attattaacc ctaaaacagc attgttacca tctgacagtg tgtttgcagaagaaaggaac 4020 ctcaaaggaa ttctagaaga atctccatct gaagcagaag atttcatttctggaattaca 4080 cagactatgg tagaagctgt agctgaagta gaaaaaaatg aaactgtttcggaaatattg 4140 ccatcaactt gtattgtgac gttagtacca ggaattccca ctggggatgagaagacagtg 4200 gacaaaaaga atatttctga aaaaaaaggt aacatggatg aaaaggaggagaaggaattt 4260 aatactaagg aaaccagaat ggatcttcaa ataggaacag agaaggctgaaaagaatgaa 4320 ggtaggatgg atgcagaaaa ggtggaaaag atggcagcaa tgaaagaaaagcctgcagaa 4380 aacactttat tcaaggcata cccaaataaa ggagtgggtc aggctaataagcctgatgaa 4440 actagtaaaa ctagtattct ggctgtatca gatgtatcta gcagtaaaccaagcatcaag 4500 gctgttatag tctcttctcc taaggcaaaa gctacagttt caaaaactgaaaatcagaaa 4560 agttttccaa aatctgtgcc cagagatcaa ataaatgctg aaaagaaactttcagccaag 4620 gaatttggtc tgcttaaacc cacaagtgcc aggtcaggct tggcagaaagcagcagtaaa 4680 ttcaaaccta ctcagagcag tcttaccaga ggaggcagtg gaaggatctcagccctgcaa 4740 ggcaagcttt ctaaactgga ttacagagat ataacaaaac aatctcaggaaacagaggct 4800 agaccttcca tcatgaaacg ggatgacagc aacaataaga ctttggctgagcaaaacact 4860 aagaatccta aaagcactac tggtagaagt tccaaatcta aagaggagccattatttcca 4920 tttaatttgg atgaatttgt tactgtggat gaggttatag aagaagtgaatccttctcag 4980 gccaagcaga atccactaaa gggaaaaagg aaagaaactc tcaaaaatgttcctttctct 5040 gaacttaact taaagaagaa aaaggggaaa acttccactc ctcgtggtgttgagggagaa 5100 ctatcttttg tgacattgga tgagattggg gaagaggaag atgcagctgcacatctagca 5160 caagctctag tcactgtgga tgaagtaatt gatgaagaag aactaaatatggaagaaatg 5220 gtaaaaaatt caaattcact ttttacatta gatgaattaa ttgaccaagatgattgcatt 5280 tcccacagtg aacctaaaga tgttactgtt ctgtcagtgg ctgaagaacaagatctcctc 5340 aaacaggaac gcttggtaac tgtggatgaa attggagaag tggaagagctacctttgaat 5400 gagtcagcag acataacttt tgccacttta aatactaaag gaaatgaaggagatatcgta 5460 agggattcca ttggcttcat ttcttctcag gtgcccgaag acccttctactttagttact 5520 gtagatgaaa tacaagatga cagcagtgat ttgcatttag tgactttggatgaagtaact 5580 gaagaggatg aagactctct ggcggatttt aacaacctta aagaagagcttaattttgtt 5640 actgttgatg aagttggaga ggaggaagat ggagataatg atttaaaagttgagttagca 5700 caaagcaaaa atgaccatcc cacagataaa aaagggaata gaaagaagagagctgtggac 5760 acaaaaaaga caaaacttga atccttgtcc caagtgggtc cagtaaatgagaatgttatg 5820 gaagaagatc taaaaaccat gattgaaaga cacttaacag ctaaaactccaaccaagaga 5880 gttagaattg ggaaaactct gccatcagaa aaagctgttg tgacagaaccagcaaaaggt 5940 gaagaggcct tccagatgag tgaagttgat gaggaatctg gattaaaggattcagaacca 6000 gagcgaaaac gcaagaagac tgaagactct tcttcaggca aatcagtggcgtctgatgtc 6060 cctgaggaat tagactttct tgtacctaag gctggattct tctgtccaatttgttccctc 6120 ttctactcag gtgaaaaagc aatgacaaat cactgcaaga gtacacgtcataagcaaaat 6180 actgagaaat ttatggccaa gcaaagaaag gaaaaggagc agaatgaggctgaagaaaga 6240 agctctaggt gattggggga aaggaaagaa ttcactagaa atttgtttagggtccagttg 6300 atttgtgtat ttttgttatc atttaatttg taattttcgt ttcagaagcaaatattcgtg 6360 ttgtacaaat ttctgattgc cctaaatgta gagagactga tggggaaagtatgatgggtt 6420 tgatttttat atcaaatcat caggcatgga gaaatatctt ttagaagtgttaaaataaat 6480 gttcctactg tatatttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaaaaaaaaaaaa 6540 aaaaaaaaaa aaaaaaaaaa aaaaaaacaa a 6571 173 3205 DNAHomo sapiens 173 cgactcgtcg ccattcccgg agcaggtcgg cctcggccca ggggcgagtatccgttgctg 60 tgtcggagac actagtcccc gacaccgaga cagccagccc tctcccctgcctcgcggcgg 120 gagagcgtgt ccggccggcc ggccggcggg gctcgcgcaa cctccctcgcctccccttcc 180 cccgcagcct ccgccccgcc aggcccggcc cggactcccg agccccggcctcctcgtcct 240 cggtcgccgc tgccgccggg cttaacagcc ccgtccgccg cttctcttcctagtttgaga 300 agccaaggaa ggaaacaggg aaaaatgtcg ccatgaaggc cgagaaccgctgccgccgcc 360 gacccccgcc ggccctgaac gccatgagcc tgggtccccg ccgcgcccgctccgctccga 420 ctgccgtcgc cgccgaggcc cccgttgatg ccgctgagct cccccaacgccgccgccacc 480 gcctccgaca tggacaagaa cagcggctcc aacagctcct ccgcctcttcgggcagcagc 540 aaagggcaac agccgccccg ctccgcctcg gcggggccag ccggcgagtctaaacccaag 600 agcgaattac taatttcagc tggattcaat ttgttgtcag ttgattctgtagtaaggcca 660 tatgttgccc ctctggaggt gcttgtcaac tactctggat gatggatggaaagaactcca 720 gtggatccaa gcgttataat cgcaaacgtg aactttccta ccccaaaaatgaaagtttta 780 acaaccagtc ccgtcgctcc agttcacaga aaagcaagac ttttaacaagatgcctcctc 840 aaaggggcgg cggcagcagc aaactcttta gctcttcttt taatggtggaagacgagatg 900 aggtagcaga ggctcaacgg gcagagttta gccctgccca gttctctggtcctaagaaga 960 tcaacctgaa ccacttgttg aatttcactt ttgaaccccg tggccagacgggtcactttg 1020 aaggcagtgg acatggtagc tggggaaaga ggaacaagtg gggacataagccttttaaca 1080 aggaactctt tttacaggcc aactgccaat ttgtggtgtc tgaagaccaagactacacag 1140 ctcattttgc tgatcctgat acattagtta actgggactt tgtggaacaagtgcgcattt 1200 gtagccatga agtgccatct tgcccaatat gcctctatcc acctactgcagccaagataa 1260 cccgttgtgg acacatcttc tgctgggcat gcatcctgca ctatctttcactgagtgaga 1320 agacgtggag taaatgtccc atctgttaca gttctgtgca taagaaggatctcaagagtg 1380 ttgttgccac agagtcacat cagtatgttg ttggtgatac cattacgatgcagctgatga 1440 agagggagaa aggggtgttg gtggctttgc ccaaatccaa atggatgaatgtagaccatc 1500 ccattcatct aggagatgaa cagcacagcc agtactccaa gttgctgctggcctctaagg 1560 agcaggtgct gcaccgggta gttctggagg agaaagtagc actagagcagcagctggcag 1620 aggagaagca cactcccgag tcctgcttta ttgaggcagc tatccaggagctcaagactc 1680 gggaagaggc tctgtcggga ttggccggaa gcagaaggga ggtcactggtgttgtggctg 1740 ctctggaaca actggtgctg atggctccct tggcgaagga gtctgtttttcaacccagga 1800 agggtgtgct ggagtatctg tctgccttcg atgaagaaac cacggaagtttgttctctgg 1860 acactccttc tagacctctt gctctccctc tggtagaaga ggaggaagcagtgtctgaac 1920 cagagcctga ggggttgcca gaggcctgtg atgacttgga gttagcagatgacaatctta 1980 aagaggggac catttgcact gagtccagcc agcaggaacc catcaccaagtcaggcttca 2040 cacgcctcag cagctctcct tgttactact tttaccaagc ggaagatggacagcatatgt 2100 tcctgcaccc tgtgaatgtg cgctgcctcg tgcgggagta cggcagcctggagaggagcc 2160 ccgagaagat ctcagcaact gtggtggaga ttgctggcta ctccatgtctgaggatgttc 2220 gacagcgtca cagatatctc tctcacttgc cactcacctg tgagttcagcatctgtgaac 2280 tggctttgca acctcctgtg gtctctaagg aaaccctaga gatgttctcagatgacattg 2340 agaagaggaa acgtcagcgc caaaagaagg ctcgggagga acgccgccgagagcgcagga 2400 ttgagataga ggagaacaag aaacagggca agtacccaga agtccacattcccctcgaga 2460 atctacagca gtttcctgcc ttcaattctt atacctgctc ctctgattctgctttgggtc 2520 ccaccagcac cgagggccat ggggccctct ccatttctcc tctcagcagaagtccaggtt 2580 cccatgcaga ctttctgctg acccctctgt cacccactgc cagtcagggcagtccctcat 2640 tctgcgttgg gagtctggaa gaagactctc ccttcccttc ctttgcccagatgctgaggg 2700 ttggaaaagc aaaagcagat gtgtggccca aaactgctcc aaagaaagatgagaacagct 2760 tagttcctcc tgcccctgtg gacagcgacg gggagagtga taattcagaccgtgttcctg 2820 tgcccagttt tcaaaattcc ttcagccaag ctattgaagc agccttcatgaaactggaca 2880 caccagctac ttcagatccc ctctctgaag agaaaggagg aaagaaaagaaaaaaacaga 2940 aacagaagct cctgttcagc acctcagtcg tccacaccaa gtgacactactggcccaggc 3000 taccttctcc atctggtttt tgtttttgtt tttttttccc ccatgcttttgtttggctgc 3060 tgtaattttt aagtatttga gtttgaacag attagctctg gggggagggggtttccacaa 3120 tgtgaggggg aaccaagaaa attttaaata cagtgtattt tccagcttcctgtctttaca 3180 ccaaaataaa gtattgacac aagag 3205 174 250 DNA Homosapiens 174 tattttacag gacattttct ttaactttgc aaactggtct tcctgctggcacatactgtg 60 atgtcatttc tggagataaa attaatggca attgcacagg cattaaaatctacgtttctg 120 acgatggcaa agctcatttt tctattagta actctgctga ggatccatttattgcaattc 180 atgctgaatc taaattataa aatttaaaat taaatgcata tcctcaaaacaatagccaag 240 tgtgtttctt 250 175 1266 DNA Homo sapiens 175 atgttccgagcggcggctcc ggggcagctc cggcgggcgg cctcattgct acgatttcag 60 agtaccctggtaatagctga gcatgcaaat gattccctag cacccattac tttaaatacc 120 attactgcagccacacgcct tggaggtgaa gtgtcctgct tagtagctgg aaccaaatgt 180 gacaaggtggcacaagatct ctgtaaagta gcaggcatag caaaagttct ggtggctcag 240 catgatgtgtacaaaggcct acttccagag gaactgacac cattgatttt ggcaactcag 300 aagcagttcaattacacaca catctgtgct ggagcatctg ccttcggaaa gaaccttttg 360 cccagagtagcagccaaact tgaggttgcc ccgatttctg acatcattgc aatcaagtca 420 cctgacacatttgtgagaac tatttatgca ggaaatgctc tatgtacagt gaagtgtgat 480 gagaaagtgaaagtgttttc tgtccgtgga acatcctttg atgctgcagc aacaagtggc 540 ggtagtgccagttcagaaaa ggcatcaagt acttcaccag tggaaatatc agagtggctt 600 gaccagaaattaacaaaaag tgatcgacca gagctaacag gtgccaaagt ggtggtatct 660 ggtggtcgaggcttgaagag tggagagaac tttaagttgt tatatgactt ggcagatcaa 720 ctacatgctgcagttggtgc ttcccgtgct gctgttgatg ctggctttgt tcccaatgac 780 atgcaagttggacagacggg aaaaatagta gcaccagaac tttatattgc tgttggaata 840 tctggagccatccaacattt agctgggatg aaagacagca agacaattgt ggcaattaat 900 aaagacccagaagctccaat tttccaagtg gcagattatg gaatagttgc agatttattt 960 aaggtagttcctgaaatgac tgagatattg aagaaaaaat gaatcaggat catgccttaa 1020 aaagaaaacttttgttaaag tattccactg aaatcacaga tatttgtggg tattataaca 1080 atcattggaaagcatggaga gctacatttc ataatttgag ggaaaatttc taacagatgc 1140 cagaatgcttgtttatggga ttgctgtgtt tccttttaat tatttgtggt tccaaacaat 1200 tattgtttgaacttttttaa ttctgtacta aaatctataa taaagctttt ccacagcttt 1260 aaaact 1266176 1471 DNA Homo sapiens 176 ggaactgcca cgatgctgcc actttggactctttcactgc tgctgggagc agtagcagga 60 aaagaagttt gctacgaaag actcggctgcttcagtgatg actccccatg gtcaggaatt 120 acggaaagac ccctccatat attgccttggtctccaaaag atgtcaacac ccgcttcctc 180 ctatatacta atgagaaccc aaacaactttcaagaagttg ccgcagattc atcaagcatc 240 agtggctcca atttcaaaac aaatagaaaaactcgcttta ttattcatgg attcatagac 300 aagggagaag aaaactggct ggccaatgtgtgcaagaatc tgttcaaggt ggaaagtgtg 360 aactgtatct gtgtggactg gaaaggtggctcccgaactg gatacacaca agcctcgcag 420 aacatcagga tcgtgggagc agaagtggcatattttgttg aatttcttca gtcggcgttc 480 ggttactcac cttccaacgt gcatgtcattggccacagcc tgggtgccca cgctgctggg 540 gaggctggaa ggagaaccaa tgggaccattggacgcatca cagggttgga cccagcagaa 600 ccttgctttc agggcacacc tgaattagtccgattggacc ccagcgatgc caaatttgtg 660 gatgtaattc acacggatgg tgcccccatagtccccaatt tggggtttgg aatgagccaa 720 gtcgtgggcc acctagattt ctttccaaatggaggagtgg aaatgcctgg atgtaaaaag 780 aacattctct ctcagattgt ggacatagacggaatctggg aagggactcg agactttgcg 840 gcctgtaatc acttaagaag ctacaaatattacactgata gcatcgtcaa ccctgatggc 900 tttgctggat tcccctgtgc ctcttacaacgtcttcactg caaacaagtg tttcccttgt 960 ccaagtggag gctgcccaca gatgggtcactatgctgata gatatcctgg gaaaacaaat 1020 gatgtgggcc agaaatttta tctagacactggtgatgcca gtaattttgc acgttggagg 1080 tataaggtat ctgtcacact gtctggaaaaaaggttacag gacacatact agtttctttg 1140 ttcggaaata aaggaaactc taagcagtatgaaattttca agggcactct caaaccagat 1200 agtactcatt ccaatgaatt tgactcagatgtggatgttg gggacttgca gatggttaaa 1260 tttatttggt ataacaatgt gatcaacccaactttaccta gagtgggagc atccaagatt 1320 atagtggaga caaatgttgg aaaacagttcaacttctgta gtccagaaac cgtcagggag 1380 gaagttctgc tcaccctcac accgtgttaggagactactg ttatttgacc aatgaattga 1440 cttctaataa aatctagtgg tgatgcaaaa a1471 177 985 DNA Homo sapiens 177 gcggagctgg gtgcgagcgc cctaccgctttcgctttccc ttcgcggtgc ccactccact 60 ccttgtgcgg cgctaggccc cccgtcccggtcatggccat gctcagggtc cagcccgagg 120 cccaagccaa ggtggatgtg tttcgtgaagacctctgtac caagacagag aacctgctcg 180 ggagctattt ccccaagaag atttctgagctggatgcatt tttaaaggag ccagctctca 240 atgaagccaa cttgagcaat ctgaaggccccattggacat cccagtgcct gatccagtca 300 aggagaaaga gaaagaggag cggaagaaacagcaggagaa ggaagacaag gatgaaaaga 360 agaaggggga ggatgaagac aaaggtcctccctgtggccc agtgaactgc aatgaaaaga 420 tcgtggtcct tctgcagcgc ttgaagcctgagatcaagga tgtcattgag cagctcaacc 480 tggtcaccac ctggttgcag ctgcagatacctcggattga ggatggtaac aattttggag 540 tggctgtcca ggagaaggtg tttgagctgatgaccagcct ccacaccaag ctagaaggct 600 tccacactca aatctctaag tatttctctgagcgtggtga tgcagtgact aaagcagcca 660 agcagcccca tgtgggtgat tatcggcagctggtgcacga gctggatgag gcagagtacc 720 gggacatccg gctgatggtc atggagatccgcaatgctta tgctgtgtta tatgacatca 780 tcctgaagaa cttcgagaag ctcaagaagcccaggggaga aacaaaggga atgatctatt 840 gagagccctc tctcccattc tgtgatgagtacagcagaga ccttcctgct ttttactggg 900 gactccagat tttccccaaa cttgcttctgttgagatttt tccctcacct tgcctctcag 960 gcacaataaa tatagttata ccact 985 1782002 DNA Homo sapiens 178 ctcttctcac atcagcgggt ccaggcccaa ccgacagactatgggggctc cttcaccagg 60 cgctgcgtgg agtggctgct gggcctctac ttcctcagccacatccccat caccctgttc 120 atggacctgc aggcggtcgt gccgcgcgag ctctacccagtcgagtttag aaacctgctg 180 aagtggtatg ctaaggagtt caaagaccca ctgctacaggagcccccagc ctggtttaag 240 tcctttctgt tttgcgagct tgtgtttcag ctgcctttctttcccattgc aacgtatgcc 300 ttcctcaaag gaagctgcaa gtggattcga actcctgcaatcatctactc tgttcacacc 360 atgacaacct taattctgat actctccaca tttctgtttgaggatttctc caaagccagt 420 ggtttcaagg gacaaagacc tgagactttg catgaacggttaacccttgt gtctgtctat 480 gccccctact tactcatccc attcatactt ttaattttcatgttgcggag cccctactac 540 aagtatgaag agaaaagaaa aaaaaaatga aggaaacaaccactggccca gggtagagat 600 gcctacaggg tggttgcttg ttggatacat acaggaacactgctcagaac ccacgtcttc 660 agcagcattt gaaacactgg cagcaatgca caagagcaagatggtgtcag gaaccatgtc 720 aaaccctcac cttcttccat tttttttttt tttttgagacagtctcactc tgttgccagg 780 ctggagtaaa gggcagtggc atgatctcgg ctcactgcaacctccgcctc ctgggctcaa 840 gccatcttcc ttagcctccc aagtagctag aactacaggtgtgtaccaac acgtatggct 900 aatttgtttt gttttttttg tgtgtgtgga gacagggttttgccatgttg cccaggttgg 960 tctcgaacgc ctaggctcaa gtgatctgcc cacctcagtctccctaagtg ctgggattac 1020 agacgtgaac cactgggccc agcccaaacc ttcaccttctaagggcactg ggatgaacag 1080 accgatcggc ttgagggtgg gcaaaggggt gtgggctaggttataaggaa gtggtaccaa 1140 ataactgtgt tgcctgagtt ccaccgcaag attactaaaagcaggaccag accagaaact 1200 gctaaagaac atggcctgtt tgacatgttc atgagtcacctgacccacag catatatgct 1260 tatgactaaa ccctccactc ctgattctca agagtgtatcacctgtcagc aaaatgaata 1320 gtgggatatt ttgggccatt ttaaatgtga aattttgcctctttaatgtt aattcaaaac 1380 tatatcaatg ttttcttgtt cccacctcta acccaaggaaaaaagagaaa acatactatg 1440 caaaggaagt ttaaacttaa gttttcctta agggtcagcccaacaatgac tttcagtcaa 1500 atggattaaa ctggaaaatg tttttgtttc tgttgtaaacagatcatcct aggcgaaagt 1560 tttttttgtt tgtttgcttt taaattagtt tatttctaaatcttagtctt ccacatttct 1620 agaggccacc tgacacaagt ccctgtatct gaagtctagcatctcaaggc tgatctggaa 1680 gtgtgctagt atgctcccta gtggataact taatcttttaatacagttcc gtcattccca 1740 tcttgttttc agaagagaag gtggctacag ccaggcataacttatccact gtgtgcatag 1800 agggtctctt cacgttgatg cttggcattc catcagctttctctaagtct ttgctcaagt 1860 tcaaggttaa aatgatgtta gacaacaggt cccagtcagtcccctctatt ttcacccatt 1920 ttgctcacaa gccatattgg cccgattagt ggtactgtctgactcacgtg tgtgatccaa 1980 ataaaggtag ctgccgggaa tt 2002 179 1319 DNAHomo sapiens misc_feature n=a,t,g or c 179 cgcgcccgtc ccgtcgccgccgccgccgcc gcagacccct cggtcttgct atgtcgagct 60 cacccgtgaa gcgtcagaggatggagtccg cgctggacca gctcaagcag ttcaccaccg 120 tggtggccga cacgggcgacttccacgcca tcgacgagta caagccccag gatgctacca 180 ccaacccgtc cctgatcctggccgcagcac agatgcccgc ttaccaggag ctggtggagg 240 aggcgattgc ctatggccggaagctgggcg ggtcacaaga ggaccagatt aaaaatgcta 300 ttgataaact ttttgtgttgtttggagcag aaatactaaa gaagattccg ggccgagtat 360 ccacagaagt agacgcaaggctctcctttg ataaagatgc gatggtggcc agagccaggc 420 ggctcatcga gctctacaaggaagctggga tcagcaagga ccgaattctt ataaagctgt 480 catcaacctg ggaaggaattcaggctggaa aggagctcga ggagcagcac ggcatccact 540 gcaacatgac gttactcttctccttcgccc aggctgtggc ctgtgccgag gcgggtgtga 600 ccctcatctc cccatttgttgggcgcatcc ttgattggca tgtggcaaac accgacaaga 660 aatcctatga gcccctggaagaccctgggg taaagagtgt cactaaaatc tacaactact 720 acaagaagtt tagctacaaaaccattgtca tgggcgcctc cttccgcaac acgggcgaga 780 tcaaagcact ggccggctgtgacttcctca ccatctcacc caagctcctg ggagagctgc 840 tgcaggacaa cgccaagctggtgcctgtgc tctcagccaa ggcggcccaa gccagtgacc 900 tggaaaaaat ccacctggatgagaagtctt tccgttggtt gcacaacgag gaccagatgg 960 ctgtggagaa gctctctgacgggatccgca agtttgccgc tgatgcagtg aagctggagc 1020 ggatgctgac agaacgaatgttcaatgcag agaatggaaa gtagcgcatc cctgaggctg 1080 gactccagat ctgcaccgccggccagctgg gatctgactg cacgtggctt ctgatgaatc 1140 ttgcgttttt tacaaattggagcagggaca gatcatagat ttctgatttt atgtaaaatt 1200 ttgcctaata cattaaagcagtcacttttc ctgtgctgtt tcaaaaaaaa aaaaaaaaaa 1260 aaaaaaaaaa aaaaaaaaaaaaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1319 180 1394 DNA Homosapiens 180 gaccagggcg ggcgagcgca gtgcagcgcc gcgcggtgcg ggcggccgagtgggggcgtc 60 atggaggatg agcggagctt ttcggatatc tgcggcggcc gcctggcgctgcagcgccgc 120 tactactccc cgtcctgccg ggaattctgc ctcagctgcc ctcggctctcgctgcgttcg 180 ctcaccgctg tcacctgcac ggtgtggctg gcggcctacg gactcttcaccctctgcgag 240 aacagcatga tcctctctgc tgccatcttc atcaccctct taggtctgcttggttatctc 300 cattttgtga agattgatca ggagactctg ttaatcattg attcccttggcattcagatg 360 acttcatctt atgcttcagg caaagaaagc actaccttca tagaaatgggcaaggtcaag 420 gatattgtca tcaatgaggc catttacatg cagaaggtga tttactacctctgcatctta 480 ttgaaagatc cagtggaacc acatgggata tcccaagtag tacccgtcttccagagtgcc 540 aagccccggc tggactgctt gattgaagta tacaggagct gccaggagatcctggcacac 600 cagaaagcca catcaacaag cccatgagcc ccagcgttca gaaggccagcattgtcttcc 660 atgggagatg actcttaagc cataggggct ggttttccgt actccaaaccatcaggtgga 720 cacagtccta ggaaccatta tggatgtagt gcatcttaga gccatagagcaggtgactgg 780 aaatctaact cagtatattt ccgtgtatta tagtgttttc cttgtaaggttttgcctact 840 ttaccaaagg aggggagacc ttaagaattt tgacacagta tgtcaaaagtaatgtcagca 900 aagaacactt tcggaaattg ctaagcatgt tcaggtttac tttgttgatgtttgtgaagc 960 aaaacaatgg gaaactgaca tcagatgtct tgagaaagct atattttccaatagtacccc 1020 ttgtgtaaag ttacgaaaaa aaacaagccc ttcagtactg gttagcaggaagaaatgtcc 1080 tacaaaagac gagtctgtca acctagtgcc tgtgttctgt acagggcttatttatttact 1140 gttaataaac agatcttcca aaacacacag ttacctggtt cacagatagctgctttttat 1200 tgacaaacaa gatcatagta tttcagtcat ggtgtcaagc acattaatacttttctgtta 1260 ctcagcattt ttttttatat cagttcaaaa gctacttttg ccaagaaggatgagacaaaa 1320 ggccagacag aaattggact ttggttttca gacatgggac tctcatgttaacaaagaata 1380 aataagcaaa tatt 1394 181 444 DNA Homo sapiens 181agatttggca cgagtcggca cgaggcggga ctgacgagaa actactaaag ttcctgggga 60agcaaagtag aatttcataa gaacaaaatg gatggagagg agaaaaccta tggtggctgt 120gaaggacctg atgccatgta tgtcaaattg atatcatctg atggccatga atttattgta 180aaaagagaac atgcattaac atcaggcacg ataaaagcca tgttgagtgg cccaggtcag 240tttgctgaga acgaaaccaa tgaggtcaat tttagagaga taccttcaca tgtgctatcg 300aaagtatgca tgtattttac gtacaaggtt cgctacacta acagctccac cgagattcct 360gaattcccaa ttgcacctga aattgcactg gaactgctga tggctgcgaa cttcttagat 420tgttaaataa aataaattat aata 444 182 8213 DNA Homo sapiens 182 cccccagcagaagggcgcga cggctgcaac atcagcggtt aaattgtaca gcctttcata 60 ggccggttcaatgcatccgt actaagattg ttaaggctga gggtccctag cctggggaaa 120 aacgaaaggaggcagagggt agggagacgg gaaggaagac aaggagggtg tagaaaacgg 180 ggagaggagggggcgggaca gcatggggaa ggcctcaggt ttactggaga gatcgtggcg 240 ttcccatagaaacgtatccc tccgcccatg acccgcgtgt tagtctcttc agttccttcc 300 gcgtcgtttcttggctgttt ccgcccagct cctttgtgcc gcgcagaaca acgagatgac 360 gcatgcgcaaagcgcagcgg ccgcatatat aaacgcgaac ccgggctctt cctcgtagtg 420 ccgccgggactcttggcggg tgaaggtgtg tgtcagcttt tgcgtcactc gagccctggg 480 cgctgcttgctaaagagccg agcacgcggg tctgtcatca tgtcgcgtta cgggcggtac 540 ggaggaggtaagaagctgga gtccggtgag ggacgttggt gtgggtgtag tgagcactgc 600 gaggccgtagggttgtcgcg gaggttggga gacggttatt ccgcgtgcgt aatggcggct 660 taggagcacgccagacgaag ccggaggcag cggaggcggg gtgctgaagg gagacgggat 720 ggcgggtgtacatctctgcc gagttccgta ctcttgggca tttttgtggc ccaatccagc 780 ctaaagcagggttgagatga cggttttcgc gttgcctttc tcggagctgc ccgccggccc 840 ccctccccccccgccctcgg ccggcggctg ccattttgcg cacattgagg accgtggtgg 900 cgcatttcctcagcgctttc ccgccacttc agcggacaga tctggccgca gctgtaagat 960 cgtggttgtgtttgagatag aacgaaattg gcagctgtga gctgcatgtt ctcgtcaaac 1020 aatcggttaaattgcggaat gggaatgggg acgtaatctg cgactggcgg ctgggttttt 1080 ttttagttatttccagcgcg gtttatggct ctggggcggg gagctggagt cttgggcgag 1140 cctgtgcctgggacgtttgc cgcggaggac gagagccggc gcagccctgc tctcctggcc 1200 cggcccctaccgaggccctc ccgccgccga cgcgctgccg ctgcgggccc gcgcgctccc 1260 ggtgcgcccggggctgccgg gactcatggg tggggccggg ccaggtcccg ccccacgcct 1320 cggtgtatcctaccacgcgt ttctgcttgt gttcgggagg gtcaccccgc attatttaga 1380 acgttaagaattttgtcaaa agtctagttt ctcggggatt tgcggacttc accagtttta 1440 cgactaagttttgtcttgga tagagggcat taaatgtgct ttacccaatc ttgaggatgg 1500 cccgttttaaggcaagtaag taattgaaac ttgggccaga ttttgcataa cgtgcattct 1560 tctatttgcgtttttaaaca gaaaccaagg tgtatgttgg taacctggga actggcgctg 1620 gcaaaggagagttagaaagg gctttcagtt attatggtcc tttaagaact gtatggattg 1680 cgagaaatcctccaggattt gcctttgtgg aattcgaaga tcctagagat gcagaagatg 1740 cagtacgaggactggatgga aagtaagtaa gatgttatga atcttctgtt cattaaaata 1800 tactgtggctagataatgaa cttagtgcta aatttggatt ctgaagtctg gaagagacct 1860 taaatagctggtcatagtgt taaatgctaa aggcacacga aggttaaaga agatagcgga 1920 gatggagttagggcttggta aagaccgcca aagtttgttg ggggggaagg agtggttgga 1980 aagagtgagtggttggaaag agttcttttt aaatctataa gtcctgaata tatttttaac 2040 tttagaattttgttaatttg cttttattag ggtgatttgt ggctcccgag tgagggttga 2100 actatcgacaggcatgcctc ggagatcacg ttttgataga ccacctgccc gacgtccctt 2160 tgatccaaatgatagatgct atgagtgtgg cgaaaaggga cattatgctt atgattgtca 2220 tcgttacagccggcgaagaa gaagcaggta tttattttaa taaaggaatg gttggtattc 2280 tagttaatcaagtaattctt ttattagcaa ggcagaaact agtgtttttc tataaacttg 2340 aatgttaattgtacaggtgt attttacaat ttgtgtttaa ttaaaaaaat gttactatat 2400 taataatcaacctggtcaaa acctttcagg tttcttcgtt tgagtcagtc gccttgattc 2460 agaatgtcacgagccttatg atatcatgct gaggcgcctt gcaaatccga caattaagat 2520 cctcctagaccttgaggtga tcagcataag aggccagatc ccctcgagtc atctacacct 2580 agcttcaccttattctttaa agggcagaaa atttgagacg gtgatcgccg taacagtaaa 2640 tttggcttacaattggggcc cccctccggt ttagaaagag gaacaccaga ttgaccacat 2700 tcccaactagaaaaatcttc ttgcgtcaat caagcctcac ctggctcatt tggctgtcag 2760 tttgatcgtcgttagattga agaaaacatc tagatgcagc gatcggctat agatacttct 2820 agatcgtctagatctactag accatgggcc aaagagggtc gacctgcaaa cttgcaaggt 2880 ttatgttaaatacacattac agtgttttat attatgtaat gctaagttgt aattcagctt 2940 ttaacaaatctttttttagg tagtaaaaaa aaaaatactc aacaactaat aggcccagag 3000 tttatttccaaatgagacac taaatttaaa tagttttgag atttgatttc agcagaggca 3060 cacaaactcttaaaaacgag ttattgtctg acattttgtt ttttctctaa cttgaaaaat 3120 aggtcacggtctagatcaca ttctcgatcc agaggaaggc gatactctcg ctcacgcagc 3180 aggagcaggggacgaaggtg agatcttgtt taactgaagt ctttctgtat tattattaaa 3240 ttcactggtagtccaacaca gaaaaagctc attatttttt ttggagacag ggtcttgctc 3300 tgtcacccgggctggagtac aggggcataa ccacgactca ctgctgcctt gatgatctct 3360 tgggtttaagcagttctcct acctcagcct cccgagtagc tgggactgta ggcactgcca 3420 ccatacccagctaattttta tttttgtaga aatggtcttg cactgtttcc caggctggtc 3480 tcaagctcctgggctcaaac gatcctcccg cagtgctggg attatgggca tgagccactg 3540 caccgttccccagttgaagt cttaacaggc caaaaaaaaa aaaaactgtg gagatggact 3600 taaagttctttattttaggt caaggtcagc atctcctcga cgatcaagat ctatctctct 3660 tcgtagatcaagatcagctt cactcagaag atctaggtct ggttctataa aaggatcgag 3720 gtatttccagtatgtaacac tttttttcct tacttgtgtt tggattgttc acatcttatc 3780 agtagagtgtcttaaggaca taattcaaat ggattgcttc agggaatatt tgagatgtaa 3840 aagtttggaatttatgtgta acttgtaaca taaatattac cctagtttca cagatgaaga 3900 aaagggctactagagatttt aaggcttgtt aggccgtgtg gtagacaagg gtcccaagca 3960 atacagctctactcaacact ctgggtaggc atgttgctat aaacttttct ggcttcagat 4020 tggatgatactagctctgaa agatggtaat tgattttccc gacaaaaagg cctattagca 4080 ccaggaaaagagatcagaag caagtagaaa catttctcat ttttggaatg atggggttga 4140 tttgagacactggaaagttg actagggcag tagtgtgtac acagaaatga atgtggattt 4200 tttttttagaccgtttcaga cctgaaaaaa ctaaagaacc agagctttac tatttgtaga 4260 aggccttaaaaggagataga atggaaaaaa ttgtaaaata agtattgcaa catgtaatta 4320 acaatattgttatctgtacc aacgataaaa ccgtggtacg gaatgctact gggagttaaa 4380 ttgctgtttaatagcacaaa acctttaaat gcaggaattc tgaatcttgt ggtctatttg 4440 agaaagctatgaaccatctc tttagataaa tttaaaagat agatatgtca gtctgatttg 4500 gtttgtctgacagattgatg gctctcaaac ataacttgat ccgggaagaa gcctgacaaa 4560 tggggggcggctttcttttc gtctggcctt atcacctgaa ttagtctcag ttcaggggtc 4620 tggttattttcatcctgcct tagcctcctg agtagctggg actgccattg tgtaccacag 4680 tgcccagctgagggatctgt gccttaagtg aggttagttt tgcttccttc ataccagtct 4740 catcaaatgaaaaccatgta tttcccttgg atattacaca gtgtttgaga atgttatacc 4800 tgtacagaaactaaccaatt gagtgataga aacaagtaat tgaaatgggg gttccttatg 4860 tctggtaacactttgtttga cagtgtgtta gacagaataa ggcaagtgtt gcatcttgtt 4920 tagttttagcttctttatgc ctgaccaacc taatacagtg ttgagtagtt aaggaaattc 4980 ctttggactgattgatataa ttgtgttttt tcactttttt tattaagatc cccgtcgagg 5040 tcaagatcaagatccaggtc tatttcacga ccaagaagca ggtagggtaa aaatttgatt 5100 atccttttctagttatatgg caccaatatc caaagagttc aaagtgtttt taattgttga 5160 aattttaagtgttaactcta aacttaggtt ttagtgggaa cacagtacct tatttgtgta 5220 tgtcctatttattactggct gactttccct gaacaaggga atgtaaaact atagtgagaa 5280 agaagcttatgacttggggg attatattaa agaggccctt gttagaactg ataggtgcat 5340 ggagaagcatcctgaaatcg atgtgcttaa agcagaatgt aaaagattaa tcatgatgta 5400 gtaattgagtcattttttga aaaacagttg ttgaaagatt ggcttttgtt agcaacaact 5460 ggtaggatgtttttcagttt aagtgcagtc tgacatttta agcttaggac atttgggggt 5520 tttacggtattggtgactac aagaaaggga ttggttagta ctctttcttt aatagaattt 5580 ctcatgttttgacagccgat caaagtccag atctccatct ccaaaaagaa ggtaagctaa 5640 atgttttgttgccaaatctt gcctgtcaag tgtggcctct gcagaatttg tttgcttact 5700 gctttgcagtctttgagctc tttggagaat tggtgctata tagattaaaa tactatgcta 5760 agtttctgaaatactttttt tttttgattc agtaacatta gtttatactt ttgctggaaa 5820 tacttagtcataaaatgtta gggtgattat taagatgtga ttggtcctgt gagtacttgg 5880 tagaaattttggtaagatag atgccttttc cccacatgta caatagatac aaagtgtgga 5940 gaaaagtcttggaaatagtt acctgcctag tgcttcttta tgaccagaaa acttcaaata 6000 gttgtcatatttatctagtg cttcttaatg accagaagac ttcaaatagt tgtcatattt 6060 aactgcaggttgaccttgca attttgacaa ggaggatagc ctaatttttt tttttttctg 6120 ggatggagttttcgctctgt ccccaggctt ggagtgcagt ggctcaatct tggctcactg 6180 cagcctccgattcccgggtt caagcaatta tcctgtctca gcctcttgag cagttgggat 6240 tacaggcacccaccgccaag cctggctaat tttttgtatt tctagtagag acggagtttc 6300 accatgttggcgaggttggt cttaaactcc tgatcttagg tgatcacctg cctcggcctc 6360 tcccaaagtgctggggttac aggcgtgagc caccgtgcct ggccagggta gcctaatctt 6420 aagccagggacaaaagatga atatatgtaa gtttcatgtc atttttaggt ctttgctata 6480 ggaaattagtaccttaggcc acctttgaag ttattgaaag ttagtacatg tacatgagag 6540 tttcaattgacactaattgg atccaaacct aatgtttttc tttttagtcg ttccccatca 6600 ggaagtcctcgcagaagtgc aagtcctgaa agaatggact gaagctctca agttcaccct 6660 ttagggaaaagttattttgt ttacattatt ataagggatt tgtgatgtct gtaaagtgta 6720 acctaggaaagataattcaa ccatctaatc aaaatggatc tggattacta tgtaaattca 6780 cagcagtaaggataatataa attttgttga atgtatgaac atcatatggt ctgaaaatgt 6840 gggtttttatttggcacatt taaataacat gtttctaact agatttttga tttgtgttca 6900 atattaacacttcttaattt gatatatttg agagtcagac attataattg ttaatcctta 6960 ttcatacatacctacattca gaattgaaag gtgttggtta agtcttgaac atcactattc 7020 tatgcataaaacttggccag gatcttaagg gactttgaaa attccatctt acccttgtag 7080 ctctgggtaagatgacctga gtcccttatg atacagcctg aatgcatcat gacagatcct 7140 tagttagctaatccgtttga agttggtgtt agtaggtatt gtatgatcag tggtgaagca 7200 agtaggaccactgatgtgtc taaatgagca tgacaggaac taaacgaaac tgattaaatg 7260 tatgagaaatagaaactgat ttctggatga tctttatact aattgcagct ttcaggctac 7320 taggtggcatagtgttaatt aggactcccc aagatatggg gagttctact ctcaatggtc 7380 ttgtttctttgctttctaca ttagttaacc agttttatac caaaaaatgc atgtttgagg 7440 aattgtctgaaattgggaca aaacaccttc atgtaaacca gctttgcaaa attttccagc 7500 ccagatactcttcatctatt caaatggatt gtcttattct gagcaaagac ctgttgttaa 7560 tcttcaagctaggttttgca gttcccaacc acaacattct tctattttgc caggctggtg 7620 caaagtaattaaagatgtca atcagaaatg tcaatgagac taaagtggtt ttgtaaatct 7680 cagctatatttagcaacact ccatgtagct aatatttttt ggtagcatct ggtagacctt 7740 agaatgttacatagccagta ggttctttat tcaaatttta agtatcttaa gaatagtagg 7800 gcagtaacagttacttttga gagttttctg gtcaagcttt taccaggcat tctctagcct 7860 tggtacaaaaaaaaaaaaaa cctgctggtt gcgcagatac ctaggcttgt ccattttatg 7920 catttcagcaaagtcattgg agactattgc aacttgggaa tactggtctg catcaagttt 7980 aattcggtagtttgaccgct agtatgttgg aagttatttg gattgttttt ggaattttga 8040 ctggctgaattatggttggt ataaagttat gtgtataact ggcaggctta tttatctgtt 8100 gcacttggttagctttaatt gttctgtatt atttaaagat aagtttactc aacaataaat 8160 ctgcagagattgaacaaata atcctgatac ttaatttttg gaagtgggag ctc 8213 183 3228 DNA Homosapiens 183 gcgccgagga tgaggaggtg caacagcggc tccgggccgc gccgtcgctgctgctgctgc 60 tgctgtggct gctcgcggtt cccggcgcta acgcggcccc gcggtcggcgctctattcgc 120 cttccgaccc gctgacgctg ctgcaggcgg acacggtgcg cggcgcggtgctgggctccc 180 gcagcgcctg ggccgtggag ttcttcgcct cctggtgcgg ccactcgatcgccttcgccc 240 cgacgtggaa ggcgctggcc gaagacgtca aacgctggag gccggccctgtatctcgccg 300 ccctggactg tgctgaggag accaacagtg cagtctgcag agacttcaacatccctggct 360 tcccgactgt gaggttcttc aaggccttta ccaagaacgg ctcgggagcagtatttccag 420 tggctggtgc tgacgtgcag acgctgcggg agaggctcat tgacgccctggagtcccatc 480 atgacacgtg gcccccagcc tgtcccccac tggagcctgc caagctggaggagattgatg 540 gattctttgc gagaaataac gaagagtacc tggctctgat ctttgaaaagggaggctcct 600 acctgggtag agaggtggct ctggacctgt cccagcacaa aggcgtggcggtcgcgaggg 660 tcgtgaacac agaggccaat gtggtgagaa agtttggtgt caccgacttcccctcttgct 720 acctgctgtt ccggaatggc tctgtctccc gagtccccgt gctcatggaatccaggtcct 780 tctataccgc ttacctgcag agactctctg ggctcaccag ggaggctgcccagaccacag 840 ttgcaccaac cactgctaac aagatagctc ccactgtttg gaaattggcagatcgctcca 900 agatctacat ggctgacctg gaatctgcac tgcactacat cctgcggatagaagtgggca 960 ggttcccggt cctggaaggg cagcgcctgg gtggccctga aaaagtttgtggcagttctg 1020 gccaagtatt tcctgggcgg cccttagtcc agaactttct gcactccgtgaatgaatggc 1080 tcaagaggca gaagagaaat aaaattccct acagtttctt taaaactgccctggacgaca 1140 ggaaagaggg tgccgttctt gccaagaagg tgaactggat tggctgccaggggagtgagc 1200 cgcatttccg gggctttccc tgctcctgtg ggtcctcttc cacttctagactgtgcaggc 1260 agctcggatc aaaatgtaga ccactcacag gaagcacgca aggccaaggaggtcctccca 1320 gccatccgag gctagctgca ctacttcttc ggctgccgag actgcgcaagccacttcgag 1380 cagatgctgc tgcctccatg caccgggtgg ggagtcccaa cgccgctgtcctctggctct 1440 ggtctagcca caacagggtc aatgctcgct tgcaggtgcc cccagcgaggacccccagtt 1500 ccccaaggtg cagtggccac cccgtgaact ttgttctgcc tgccacaatgaacgcctgga 1560 tgtgcccgtg tgggacgtgg aagccaccct caacttcctc aaggcccacttctccccaag 1620 caacatcatc ctggacttcc ctgcagctgg gtcagctgcc ggagggatgtgcagaatgtg 1680 cagccgcccc agagctggcg atgggagccc tggagctgga aagccggaattcaactctgg 1740 accctgggaa gcctgagatg atgaagtccc ccacaaacac caccccacatgtgccggctg 1800 agggacctga ggcaagtcga cccccgaagc tgcaccctgg cctcagagctgcaccaggcc 1860 aggagcctcc tgagcacatg gcagacgttc agaggaatga gcaggacgagccgcttgggc 1920 agtggcactt acgaagcgag acacaggggc tgcattgctg gctgagtccagggctgagaa 1980 gaaccgcctc tggggccctt tggaggtcag gcgcgtgggc cgcagctccaagcagctggt 2040 cgacatccct gaggccagct ggaggcccga gctggacggg ccgaggccagtggctgcagg 2100 tgctgggagg gggcttctct tacctggaca tcagcctctg tgtggggctctatccctgtc 2160 cttcatgggc ctgctggcat gtacacctac ttccaggcca agataaggccctgaaccgga 2220 tgctggccac cctgcagcct gaaccacctg gggaggaggc gggagagggagctgccatct 2280 ctaggcacct caagccccct gaccccattc cctcccctcc caccccttgctccttgtctg 2340 gcctagaagt gtgggaaatt caggaaaacg agttgctcca gtgaagcttcttggggttgc 2400 taggacagag agctcctttg acacaaaaga caggagcagg gtccaggttgcctcgtgcag 2460 ggagggcacg cccggcgagt ggcgataggg cagctcagtc cctggcctcttagcaccaca 2520 ttcctgtttt tcagcttatt tgaagtcctg cctcattctc actggagcctcagtctctcc 2580 tgcttggtct tggccctcaa ctggggcaag tgaagccaga ggagggtccccagctgggtg 2640 ggctggaatg gaactcctca ctagctgcct gcgcgcccac cctgctccttccggacaatg 2700 aagaagcctt tgcaccctgg gaggaaggac caccccgggc cctctatgcctggccagcct 2760 ccagctcctc agacctcctg ggtggggttt ggcttcaggg tggggtttggaagcttctgg 2820 aagtcgtgct ggtctcccag gtgaggaaag ccatggttgc tgggctgtagggtgatggtt 2880 tgtttggtgg gacctgacga gttggtggca tgggaaggat gtgggtctctagtgccttgc 2940 cctggcttag ttgaaggaga agatggctgt tttcacttcc ccccatagagctctgctccc 3000 tctgagcctg gtcttttgtc cttttttatt ttggtctcca agatgaatgctcatctttgg 3060 agggtgccag gtagaagcta gggaggggag tgtcttctct ctccaggtttcaccttccag 3120 tgtgcagaag ttagaagggt ctggcggggg cagtgcctta cacatgcttgattcccacgc 3180 taccccctgc cttgggaggt gtgtggaata aattattttt gttaaggc3228 184 400 DNA Homo sapiens 184 ggctcagtcc tctccttcat ccctctccaggcaaaaacaa agagtgtgag gccttcattt 60 gcaactgcga ccgcaacgct gccatctgcttttcaaaagc tccatataac aaggcacaca 120 agaacctgga caccaagaag tattgtcagagttgaatatc acctctcaaa agcatcacct 180 ctatctgcct catctcacac tgtactctccaataaagcac cttgttgaaa gacctcatgt 240 ttggatattg ttttattctc tgtctataaactaggtctct gcctactctt ttatttttat 300 gtatttattt tttctaggtg gagtcttgctctgtggccca ggtggatgag tgatgccacc 360 ttgcctcact gcaacctccg ctcccgggctcaagcaatcc 400 185 1051 DNA Homo sapiens 185 cctggcccac agctcacaacaactaccagg cgcagtctgc tgtgcccctg cgccacgaga 60 cccacggcgg ggaggacgtggccgtcttct ccaagggccc catggcgcac ctgctgcacg 120 gcgtccacga gcagaactacgtcccccacg tgatggcgta tgcagcctgc atcggggcca 180 acctcggcca ctgtgctcctgccagctcgg caggcagcct tgctgcaggc cccctgctgc 240 tcgctctggc cctctaccccctgagcgtcc tgttctgagg gcccagggcc cgggcaccca 300 caagcccgtg acagatgccaacttcccaca cggcagcccc cccttcaagg ggcagggagg 360 tgggggcctc ctcagcctctgcaactgcaa gaaaggggac ccaggaaacc aaagtctgcc 420 gcccacctcg ctcccctctggaatcttccc caagggccaa acccacttct ggcctccagc 480 ctttgctccc tccccgctgccctttggcca acagggtaga tttctcttgg gcaggcagag 540 agtacagact gcagacattctcaaagcctc ttatttttct agcgaacgta tttctccaga 600 cccagaggcc ctgaagcctccgtggaacat tctggatctg accctcccag tctcatctcc 660 tgaccctccc actcccatctccttacctct ggaacccccc aggccctaca atgctcatgt 720 ccctgtcccc aggccagccctccttcaggg gagttgaggt ctttctcctc aggacaaggc 780 cttgctcact cactcactccaagaccacca gggtcccagg aagccggtgc ctgggtggcc 840 atcctaccca gcgtgcccaggccgggaaga gccacctggc agggctcaca ctcctgggct 900 ctgaacacac acgccagctcctctctgaag cgactctcct gtttggaacg gcaaaaaaaa 960 attttttttt ctctttttggtggtggttaa aagggaacac aaaacattta aataaaactt 1020 tccgaggaca gagctgagtctttgtggtca g 1051 186 2450 DNA Homo sapiens 186 agagggtccg ccatgttccccggcggcgcc gccgcttggc tctggtagcc gccgcccccg 60 cccccaaccc cgcccggcccagagcctagc cgagccccgg gcccagcatg gccgccccgg 120 agccggcccg ggctgcaccgcccccacccc cgcccccgcc gccccctccc ggggctgacc 180 gcgtcgtcaa agctgtccctttccccccaa cacatcgctt gacatctgaa gaagtatttg 240 atttggatgg gatacccagggttgatgttc tgaagaacca cttggtgaaa gaaggtcgag 300 tagatgaaga aattgcgcttagaattatca atgagggtgc tgccatcctt cggagagaga 360 aaaccatgat agaagtagaagctccaatca cagtgtgtgg tgacatccat ggccaatttt 420 ttgatctgat gaaactttttgaagtaggag gatcacctgc taatacacga tacctttttc 480 ttggcgatta tgtggacagaggttatttta gtatagagca tgttctaggc actgaagaca 540 tatcgattaa tcctcacaataatattaatg agtgtgtctt atatttatgg gttctgaaga 600 ttctataccc aagcacattatttcttctga gaggcaacca tgaatgcaga caccttactg 660 aatattttac ctttaagcaggaatgtaaaa ttaagtattc ggaaagagtc tatgaagctt 720 gtatggaagc ttttgatagtttgcctcttg ctgcactttt aaaccaacag tttctttgtg 780 ttcatggtgg actttcaccagaaatacaca cactggatga tattaggaga ttagatagat 840 tcaaagagcc acctgcatttggaccaatgt gtgacttgtt atggtccgat ccttctgaag 900 attttggaaa tgaaaaatcacaggaacatt ttagtcacaa tacagttcga ggatgttctt 960 atttttataa ctatccagcagtgtgtgaat ttttgcaaaa caataatttg ttatcgatta 1020 ttagagctca tgaagctcaagatgcaggct atagaatgta cagaaaaagt caaactacag 1080 ggttcccttc attaataacaattttttcgg cacctaatta cttagatgtc tacaataata 1140 aagctgctgt attaaagtatgaaaataatg tgatgaatat tcgacagttt aactgttctc 1200 cacatcctta ctggttgcctaattttatgg atgtcttcac gtggtcttta ccgtttgttg 1260 gagaaaaagt gacagaaatgttggtaaatg ttctgagtat ttgctctgat gatgaactaa 1320 tgactgaagg tgaagaccagtttgatggtt cagctgcagc ccggaaagaa atcataagaa 1380 acaaaattcg agcaattggcaagatggcaa gagtcttctc tgttctcagg gaggagagtg 1440 aaagtgtgct gacactcaagggcctgactc ccacagggat gttgcctagt ggagtgttag 1500 ctggaggacg gcagaccctgcaaagtggta atgatgttat gcaacttgct gtgcctcaga 1560 tggactgggg cacacctcactcttttgcta acaattcaca taatgcatgc agggaattcc 1620 ttctgttttt tagttcctgtctcagcagct gacctagaca gggtagtgta ttagctagtg 1680 tctcattaat acgtgatcagggcagaaaac tgatagaatg ggtattcctt tcaattgaaa 1740 ataatggtca gttcctcagcttttcatgaa atgatatggg agcagctcat atcataatgt 1800 ctgaaatatt tatttattcatctgtctaat tcaccctttt cttttaaaag ccccagtttc 1860 agaatgtgaa tcagggatattcctgttact aaaatggaaa tgtaattcca agtttctttt 1920 ttaatttttt aaatttatgtcattgtattg gactatgctt atatttaaaa ctacttaatt 1980 tagagttaac tacctgcttaggccccagaa cattacttat gcccttcagt taccaaaaga 2040 tttgtgcaag gttttgtaccctggtaaatg atgccaaagt ttgttttctg tggtgtttgt 2100 caaatgttct atgtataattaactgtctgt aacatgctgt ttccttcctc tgcagatgta 2160 gctgctttcc taaatctgtctgtctttctt taggttagct gtatgtctgt aaaagtatgt 2220 tcaattaaat tactccatcagacacttgtc tgtcttgcaa tgtagaagca gctttgtagc 2280 accttgtttt gaggtttgctgcatttgttg ctgcactttg tgcattctga acatgaatgt 2340 aacattagat attaagtcattgttataagg ggttgaattt aaatcctgta agtcaaaatt 2400 gaaagggtgt tattaagtgtgcctttattt tgcatgaaaa taaaaagaat 2450 187 952 DNA Homo sapiens 187gcagtctgca gcatggcgta cccggggcat cctggcgccg gcggcgggta ctacccaggc 60gggtatggag gggctcccgg agggcctgcg tttcccggac aaactcagga tccgctgtat 120ggttactttg ctgctgtagc tggacaggat gggcagatag atgctgatga attgcagaga 180tgtctgacac agtctggcat tgctggagga tacaaacctt ttaacctgga gacttgccgg 240cttatggttt caatgctgga tagagatatg tctggcacaa tgggtttcaa tgaatttaaa 300gaactctggg ctgtactgaa tggctggaga caacacttta tcagttttga cactgacagg 360agtggaacag tagacccaca agaattgcag aaggccctga caacaatggg atttaggttg 420agtccccagg ctgtgaattc aattgcaaaa cgatacagca ccaatggaaa gatcaccttc 480gacgactaca tcgcctgctg cgtcaaactg agggctctta cagacagctt tcgaagacgg 540gatactgctc agcaaggtgt tgtgaatttc ccatatgatg atttcattca atgtgtcatg 600agtgtttaaa tcaagaggaa gctgcatgaa tgtaatcaac attccaactg gagctctcct 660ttgcttgtcc tctttgcctt cggtaatatg tataaactta catcacgact ttctcttaac 720agctgttgta aagtttatta ctttatgtac aactgaagtt ttgttttagt tttgataata 780aattcttgga actttaataa gatctagtct gttacaccat ttagaacttt cctcagccat 840tatcagtcat gccttatttt cttgctaaaa ctctatgtaa atttaagtat gcaaaatgtt 900taagtcacat tatttatttt tcattgtgag atactaaaaa ctgttatcag ac 952 188 996DNA Homo sapiens 188 ccagttccag cccgcacccc gcgtcggtgc ccgcgcccctccccgggccc cgccatgggc 60 ctcaccgtgt ccgcgctctt ttcgcggatc ttcgggaagaagcagatgcg gattctcatg 120 gttggcttgg atgcggctgg caagaccaca atcctgtacaaactgaagtt gggggagatt 180 gtcaccacca tcccaaccat aggcttcaat gtagaaacagtggaatataa gaacatctgt 240 ttcacagtct gggacgtggg aggccaggac aagattcggcctctgtggcg gcactacttc 300 cagaacactc agggcctcat ctttgtggtg gacagtaatgaccgggagcg ggtccaagaa 360 tctgctgatg aactccagaa gatgctgcag gaggacgagctgcgggatgc agtgctgctg 420 gtatttgcca acaagcagga catgcccaac gccatgcccgtgagcgagct gactgacaag 480 ctggggctac agcacttacg cagccgcacg tggtatgtccaggccacctg tgccacccaa 540 ggcacaggtc tgtacgatgg tctggactgg ctgtcccacgagctgtcaaa gcgctaacca 600 gccaggggca ggcccctgat gcccggaagc tcctgcgtgcatccccggga tgaccagact 660 cccggactcc tcaggcagtg ccctttcctc ccacttttcctcccccatag ccacaggcct 720 ctgctcctgc tcctgcctgc atgttctctc tgttgttggagcctggagcc ttgctctctg 780 ggcacagagg ggtccactct cctgcctgct gggacctatggaaggggctt cctggccaag 840 gccccctctt ccagaggagg agcagggatc tgggtttccttttttttttc tgttttgggt 900 gtactctagg ggccaggttg ggagggggaa ggtgagggcttcgggtggtg ctataatgtg 960 gcactggatc ttgagtaata aatttgctgt ggtttg 996189 3178 DNA Homo sapiens misc_feature n=a,t,g or c 189 agttgagcgcagtcgccgct ccagtctatc cggcactagg aacagccccg ggggcgagac 60 ggtccccgccatgtctgcgg ccatgaggga gaggttcgac cggttcctgc acgagaagaa 120 ctgcatgactgaccttctgg ccaagctcga ggccaaaacc ggcgtgaaca ggagcttcat 180 cgctcttggtgtcatcggac tggtggcctt gtacctggtg ttcggttatg gagcctctct 240 cctctgcaacctgataggat ttggctaccc agcctacatc tcaattaaag ctatagagag 300 tcccaacaaagaagatgata cccagtggct gacctactgg gtagtgtatg gtgtgttcag 360 cattgctgaattcttctctg atatcttcct gtcatggttc cccttctact acatgctgaa 420 gtgtggcttcctgttgtggt gcatggcccc gagcccttct aatggggctg aactgctcta 480 caagcgcatcatccgtcctt tcttcctgaa gcacgagtcc cagatggaca gtgtggtcaa 540 ggaccttaaagacaagtcca aagagactgc agatgccatc actaaagaag cgaagaaagc 600 taccgtgaatttactgggtg aagaaaagaa gagcacctaa accagactaa accagactgg 660 atggaaacttcctgccctct ctgtaccttc ctactggagc ttgatgttat attagggact 720 gtggtataattattttaata atgttgcctt ggaaacattt tgagatatta aagattggaa 780 tgtgttgtaagtttctttgc ttacttttac tgtctatata tatagggagc actttaaact 840 taatgcagtgggcagtgtcc acgtttttgg aaaatgtatt ttgcctctgg gtaggaaaag 900 atgtatgttgctatcctgca ggaaatataa acttaaaata aaattatata ccccacaggc 960 tgtgtactttactgggctct ccctgcacgn attttctctg tagttacatt taggntaatc 1020 tttatggttctacttcctnt aatgtacaat tttatataat tcngnaatgt ttttaatgta 1080 tttgtgcacatgtacatatg gaaatgttac tgtctgacta cancatgcat catgctcatg 1140 gggagggagcaggggaaggt tgtatgtgtc atttataact tctgtacagt aagaccacct 1200 gcaacaagctggaggaacca ttgtgctggt gtggtctact aaataatact ttaggaaata 1260 cgtgattaatatgcaagtga acaaagtgag aaatgaaatc gaatggagat tggcctggtt 1320 gtttccgtagtatatggcat atgaatacca ggatagcttt ataaagcagt tagttagtta 1380 gttactcactctagtgataa atcgggaaat ttacacacac acacacacac acacacacac 1440 acacacacacacacacacac acacagagta ccctgtaact ctcaattccc tgaaaaacta 1500 gtaatactgtcttatctgct ataaacttta catatttgtc tattgtcaag atgctacant 1560 ggannccatttctggtttta tcttcanagn ggaganacat gttgatttag tcttctttcc 1620 caatcttcttttttaancca gtttnaggnn cttctgnaga tttgnccacc tctgattaca 1680 tgtatgttctngtttgtatc atnagcaaca acatgctaat gncgacacct agctctnagn 1740 gcaattctgggagantgana ggnngtatan agtnncccat aatctgcttg gcaatagtta 1800 agtcaatctatcttcagttt ttctctggcc tttaaggtca aacacaagag gcttccctag 1860 tttacaagtcagagtcactt gtagtccatt taaatgccct catccgtatt ctttgtgttg 1920 ataagctgcacangactaca tagtaagtac agancagtaa agttaanncg gatgtctcca 1980 ttgatctgccaantcgntat agagagcaat ttgtctggac tagaaaatct gagttttaca 2040 ccatactgttaagagtcctt ttgaattaaa ctagactaaa acaagtgtat aactaaacta 2100 acaagattaaatatccagcc agtacagtat tttttaaggc aaataaagat gattagctca 2160 ccttgagntaacaatcaggt aagatcatna caatgtctca tgatgtnaan aatattaaag 2220 atatcaatactaagtgacag tatcacnnct aatataatat ggatcagagc atttattttg 2280 gggaggaaaacagtggtgat taccggcatt ttattaaact taaaactttg tagaaagcaa 2340 acaaaattgttcttgggaga aaatcaactt ttagattaaa aaaattttaa gtanctagga 2400 gtatttaaatccttttccca taaataaaag tacagttttc ttggtggcag aatgaaaatc 2460 agcaacntctagcatataga ctatataatc agattgacag catatagaat atattatcag 2520 acaagatgaggaggtacaaa agttactatt gctcataatg acttacaggc taaaantagn 2580 tntaaaatactatattaaat tctgaatgca attttttttt gttcccttga gaccaaaatt 2640 taagttaactgttgctggca gtctaagtgt aaatgttaac agcaggagaa gttaagaatt 2700 gagcagttctgttgcatgat ttcccaaatg aaatactgcc ttggctagag tttgaaaaac 2760 taattgagcctgtgcctggc tagaaaacaa gcgtttattt gaatgtgaat agtgtttcaa 2820 aggtatgtagttacagaatt cctaccaaac agcttaaatt cttcaagaaa gaattcctgc 2880 agcagttattcccttacctg aaggcttcaa tcatttggat caacaactgc tactctcggg 2940 aagactcctctactcacagc tgaagaaaat gagcacaccc ttcacactgt tatcacctat 3000 cctgaagatgtgatacactg aatggaaata aatagatgta aataaaattg agntctcatt 3060 taaaaaaaaccatgtgccca atgggaaaat gacctcatgt tgtggtttaa acagcaactg 3120 cacccactagcacagcccat tgagctancc tatatataca tctctgtcag tgcccctc 3178 190 3512 DNAHomo sapiens 190 cgagccaccc agctgagagg agaggcgccc ccggggacgc actgagattatgaggctctg 60 gcctccactg gccactcact cgtgaccctt tccaccacgg cggagccttccaagcctacc 120 tcctgccgtg tggtgatcta cctgcagcgg gagatgtcgg gggacacctgcctgtgccca 180 gcctcagggg ccaagcccaa gctcagtggc ttcaagggag gagggttgggcaacaagtat 240 gtccagctca acgtgggcgg ctctctgtac tacaccactg tgcgggccctgacccgccac 300 gacaccatgc tcaaggccat gttcagtggg cgcatggagg tgctgaccgacaaagaaggc 360 tggatcctca tagaccgttg tggaaagcac tttggcacca ttttgaattacctccgagat 420 gacaccatca ccctccctca gaaccggcaa gaaatcaagg aattgatggctgaagcaaag 480 tattacctca tccaggggct ggtgaatatg tgccagagtg ccctgcaggacaagaaggac 540 tcctaccagc ctgtgtgcaa catccccatc atcacatccc taaaggaggaggagcggctc 600 atcgaatcct ccaccaagcc cgtggtgaag ctgctgtaca acagaagcaacaacaagtat 660 tcctacacca gcaactctga cgaccacctg ctgaaaaaca tcgagctgtttgacaagctc 720 tccctgcgct tcaacggccg cgtgctcttc atcaaggatg tcattggtgacgagatctgc 780 tgctggtcct tttatggcca gggccgtaag ctggcagagg tgtgctgtacctccatcgtg 840 tatgccacgg agaagaagca gaccaaggtg gaattcccag aggcccgaatctatgaggag 900 acactcaacg tcctactcta tgagactccc cgcgtccccg acaactccttgttggaggcc 960 acaagccgta gccgcagcca ggcttccccc agtgaagatg aggagacctttgaactgcgg 1020 gaccgtgtcc gccgcatcca cgtcaagcgc tacagcactt acgatgaccggcagctcggc 1080 caccagtcta cccatcgcga ctgaccagac cctcagggag tcagggcacgggaggcccta 1140 tctcccatcc tgtggaaccc gccccattgg ccaccccatg ctgctgctgcctgggtctct 1200 gctctagcac ccagaggcat gacaggccct gctcagaggt cagagggtctgggcagagga 1260 gggaccacat tcccctgcct tgcccctgag cacttctgga gactgcgtcctgtcctatct 1320 gctcaccatc acccttcctg cccgacggag ctgcttctgc tccctggggcatatggactg 1380 acccacctcc tgctgagaac cttcccctag gccctgtgca gaagggctactgccccttag 1440 gcctcagctg ggggaaaggc agttctggtg ctgtagaggc cctggtgcagaaagtgggac 1500 gtcctttttc ctaaggtgtt taagcacagg cttgataagt ttggtttttaaaaaataatc 1560 taggaaatga ataattctaa atctagtaat gaggaaactg agcatttcttttgccctcca 1620 gggtgccaag accctacata tgacagaacc cttggccctt ctccatgcctgtgggatctg 1680 tttctttaaa gcactttgta ctgttattca ggaggttgat aatctccttgacccatgtct 1740 ttctacccta atccccactt ccctgcagaa tcaatctgag ggaggggataaagaggaagc 1800 aataaaaaaa aaacatccga cagagcagct ctggctttgc cagcctggccagcagctcag 1860 agtgcaccga ggagggaagg atggctaagc tgggaccggc agtcctcacagggtgcctgt 1920 gagaaaggac attttacccc cacatcatag tcacatcact gactcctaggtctagcacga 1980 ctgctctttg tgatcctctt gagtaccctt ggcttccagc catgctgtcctcacatacgg 2040 taaagccaaa gagctgtcac atgggccaga aacatgagcc acggcaggaagaccgtggag 2100 cccgtgggca ctgcatggtg ttggctggca tgcccatcag ctgaggacagcaaactccca 2160 gcagccccta cagaggtggc acatgcttgg ccacacatct actccctgcccacaccatct 2220 atgctcttgg ttggtgctgg ctgggatggc ggttctgccc agtggtgtctctgagcgcgg 2280 gatgacagga gcaaccgaag caccctgaag gccttcactc cttgttgggtaactcagcca 2340 tggagatgcc aagcactagc caggaggtga gttcctcttt agggctttggttttcattcc 2400 tttttgtttg gcttggccaa accagaattc agcttatctg aattattttccaaaggaatg 2460 ctgtcaggga gggactgttc tgccagccta acaaagcaac gtagccacgtatagtaccca 2520 cttctgctct ttggagagaa cacaggttat caagttcatc tctcttgactactcttatga 2580 tagctgatgc cacagagcct atgggcaaat gccagaccca gggttagacacaaggacctg 2640 aagtgacatg acggcgggac aggggaaatg tgactttcta attaggcattttatgttagt 2700 cacagtcttg aatgtataaa cagcactaag actctcaggt caggtaccttggtgatcagc 2760 tactagttct tccagccctc attgaggtaa caagataaag acaaatccacttctttggcc 2820 aaattcaggc tttggcttta tgactttccc acagagactg gaatgcgtcagcctgagacc 2880 actggcctat tttctcagct gccctcttga ggtcctttaa cactcaaattcccagctccc 2940 cactgaggtg ttgtgatgct tgccttttga cctccccatc ccctttagtccctgcttact 3000 actttgacat tcacatcctc agtgtctcag tcttttttgc cgagaaagcacagtagtctg 3060 ggactgggca tttatcttct ctgactgaaa atctctcctt ggtcttaaggaaaatactaa 3120 cattgaactc actgacatga tcttagcttc tttaatcaga ctttgtgacttaaaagtttg 3180 ggggttttct ttgaaagttt ccagccctat tcagaaagca actcttggctgtgtgcattt 3240 ttcaactcca agcagcccag gggtaagtaa acaaagtatg gatgaaggtcagattttctt 3300 gtcagtttct gagaaacctg gcagcctgct gttaacaaca caggccagtattgggtttta 3360 ttgaatttgg tatgtgacca aggtcggcct aaaggatggc gcaggtcctgggcaggaaag 3420 aatttttcct ttatcacata actgtaatat ttggttgctc agcataagtgatggaagcaa 3480 acactaattt ctaataaaat tgtgttaaac tc 3512 191 254 DNAHomo sapiens 191 ctccccacag ttcacagtga cctttgagag tgacaaattc aaggtgaagctgccagatgg 60 gcacgagctg acttttccca acaggctggg tcacagccac ctgagctacctgagcgtaag 120 gggcgggttc aacatgtcct ctttcaagtt aaaagaataa aagacttccagccgagattc 180 tctgtcctgg ttcttcttcc gagtcacacc aggatcaaca gagcttgggtgtgttcccct 240 atccctacct gcag 254 192 1316 DNA Homo sapiens 192cccgcagctc ggagcccgga gcgtcctcgg cggctgtcgg ttttcaccat ggagcagctg 60agctcagcaa acacccgctt cgccttggac ctgttcctgg cgttgagtga gaacaatccg 120gctggaaaca tcttcatctc tcccttcagc atttcatctg ctatggccat ggtttttctg 180gggaccagag gtaacacggc agcacagctg tccaagactt tccatttcaa cacggttgaa 240gaggttcatt caagattcca gagtctgaat gctgatatca acaaacgtgg agcgtcttat 300attctgaaac ttgctaatag attatatgga gagaaaactt acaatttcct tcctgagttc 360ttggtttcga ctcagaaaac atatggtgct gacctggcca gtgtggattt tcagcatgcc 420tctgaagatg caaggaagac cataaaccag tgggtcaaag gacagacaga aggaaaaatt 480ccggaactgt tggcttcggg catggttgat aacatgacca aacttgtgct agtaaatgcc 540atctatttca agggaaactg gaaggataaa ttcatgaaag aagccacgac gaatgcacca 600ttcagattga ataagaaaga cagaaaaact gtgaaaatga tgtatcagaa gaaaaaattt 660gcatatggct acatcgagga ccttaagtgc cgtgtgctgg aactgcctta ccaaggcgag 720gagctcagca tggtcatcct gctgccggat gacattgagg acgagtccac gggcctgaag 780aagattgagg aacagttgac tttggaaaag ttgcatgagt ggactaaacc tgagaatctc 840gatttcattg aagttaatgt cagcttgccc aggttcaaac tggaagagag ttacactctc 900aactccgacc tcgcccgcct aggtgtgcag gatctcttta acagtagcaa ggctgatctg 960tctggcatgt caggagccag agatattttt atatcaaaaa ttgtccacaa gtcatttgtg 1020gaagtgaatg aagagggaac agaggcggca gctgccacag caggcatcgc aactttctgc 1080atgttgatgc ccgaagaaaa tttcactgcc gaccatccat tccttttctt tattcggcat 1140aattcctcag gtagcatcct attcttgggg agattttctt ccccttagaa gaaagagact 1200gtagcaatac aaaaatcaag cttagtgctt tattacctga gtttttaata gagccaatat 1260gtcttatatc tttaccaata aaaccactgt ccagaaacaa aaaaaaaaaa aaaaaa 1316 1931481 DNA Homo sapiens 193 ctctggaaca ttagacagga tgctgatctt ctggacaatcacacttttcc tgctgggagc 60 agccaaagga aaagaagttt gctatgagga cctcgggtgcttttctgaca ctgagccctg 120 gggcgggaca gcaatcaggc ccctgaaaat tctcccctggagccctgaga agatcggcac 180 ccgcttcctg ctgtacacca atgaaaaccc aaacaactttcaaattctcc tcctctctga 240 tccatcaaca attgaggcat caaattttca aatggacagaaagacccggt tcatcatcca 300 tggcttcata gacaaaggag atgagagctg ggtgacagacatgtgcaaga aactgttcga 360 ggtggaggag gtgaactgca tctgcgtgga ctggaagaagggctcccaag ccacctacac 420 acaggctgcc aacaacgtgc gagtggtggg cgcccaggtggcccagatgc tcgacatcct 480 cttgacagag tatagctacc ccccttccaa agttcacctcattggccaca gcctgggagc 540 ccacgtggct ggagaggcag gaagcaagac tccaggcctgagcaggatta cagggttgga 600 tcctgtagaa gcaagtttcg agagtactcc tgaagaggtgcgacttgatc cctctgatgc 660 tgactttgtt gatgtgattc acacggatgc agctcccctgatcccattct tgggttttgg 720 aacgaaccaa cagatgggtc atcttgactt cttccccaatggaggagaga gcatgccggg 780 atgcaagaag aatgccctgt ctcagatcgt ggatctagatggcatctggg cgggaacccg 840 ggactttgtg gcttgcaatc acctaagaag ctacaagtattacttggaaa gcatcctcaa 900 tcccgatggg tttgctgcat atccctgcac ttcctacaagtcctttgagt ctgacaagtg 960 cttcccgtgt ccagatcaag gatgcccaca gatgggtcactatgctgata aatttgctgg 1020 caggacaagt gaagagcagc agaaattctt cttgaacacaggagaggcta gcaatttcgc 1080 tcgctggaga tatggggttt ccatcacact gtctggaagaacagccactg gtcagatcaa 1140 agttgctttg tttggaaata agggaaacac tcaccagtacagcatcttca gggggattct 1200 caaaccaggc tcaacccatt cctatgagtt tgatgcaaagctggatgttg gaacaattga 1260 gaaagtcaag tttctttgga ataacaatgt gataaatccaaccctcccca aagtgggtgc 1320 caccaagatc actgtgcaaa agggagaaga gaagacagtgtacaacttct gtagcgaaga 1380 cacagtgcgg gaagacacgc tgctcaccct cacgccctgctaagctcccg gggcgacgag 1440 gctgctgcgt tcacactaat aaaatccact ggtgcatctg t1481 194 1450 DNA Homo sapiens 194 atgctgcccc cttggaccct cggccttctcctgctggcca cagtcagagg aaaagaggtc 60 tgctacggac aacttggctg cttttctgatgaaaaaccat gggcaggaac ccttcagcga 120 cctgtaaaat tacttccctg gtcccccgaggacattgaca cccgctttct tctgtacaca 180 aatgaaaatc caaacaactt ccaactaatcactggcacgg aaccagacac cattgaggct 240 tcaaacttcc aactggaccg caagacacgcttcatcatcc atggcttctt agacaaggcg 300 gaggacagct ggccatcgga catgtgcaagaaaatgtttg aagtggagaa ggtgaactgc 360 atctgtgtgg actggaggca cgggtcccgggcaatgtaca cccaagccgt gcaaaacatt 420 cgggttgttg gggcggagac agctttcttaatacaagcac tgtcgacgca gctagggtac 480 agccttgagg acgtgcatgt catcggccacagcctgggcg cgcacacggc cgcggaggcg 540 ggcaggaggc tggggggccg cgtgggcaggatcacagggc tggatccagc agggccgtgc 600 ttccaggatg aacctgagga ggttcggttggatccatctg acgccgtgtt tgtggatgtg 660 attcacacag attcttctcc catagttccttccctaggtt tcggaatgag ccaaaaggtg 720 ggccatctgg atttctttcc aaatggaggaaaggaaatgc ccggatgtaa gaaaaatgtc 780 ctttcaacca ttactgatat tgatggaatatgggaaggaa ttggtggctt tgtgtcttgc 840 aatcacctaa gaagcttcga gtattactcaagcagcgtcc tcaaccctga tggcttcctg 900 ggctatccct gtgcctccta cgatgagtttcaggagagta agtgtttccc ttgtccagct 960 gaaggatgcc ccaaaatggg gcactatgctgaccaattta aggggaaaac aagtgctgtg 1020 gaacaaacct ttttcctgaa cacaggagagagtggtaact ttactagttg gagatataag 1080 gtatcagtca cactttctgg aaaagagaaagtgaatgggt acatcaggat tgctttgtat 1140 ggaagtaatg aaaactcgaa acaatatgagattttcaaag gatccctcaa accagatgca 1200 agtcacacgt gtgctattga tgtggattttaatgttggaa aaatacagaa agttaaattc 1260 ctctggaaca aacgtgggat aaatctatctgagcccaaac tgggggcttc ccaaatcaca 1320 gtgcaaagtg gtgaagatgg gactgagtataatttttgta gcagcgacac tgtggaagaa 1380 aacgtcttgc aatctcttta cccttgttaaaaacgtggtg cggctattgc ggtaataaaa 1440 tctttaatgc 1450 195 2304 DNA Homosapiens 195 ttggagctgc cgccgccggg actcccgtcc cagcaggaca tggatttgattgacatactt 60 tggaggcaag atatagatct tggagtaagt cgagaagtat ttgacttcagtcagcgacgg 120 aaagagtatg agctggaaaa acagaaaaaa cttgaaaagg aaagacaagaacaactccaa 180 aaggagcaag agaaagcctt tttcactcag ttacaactag atgaagagacaggtgaattt 240 ctcccaattc agccagccca gcacacccag tcagaaacca gtggatctgccaactactcc 300 caggttgccc acattcccaa atcagatgct ttgtactttg atgactgcatgcagcttttg 360 gcgcagacat tcccgtttgt agatgacaat gaggtttctt cggctacgtttcagtcactt 420 gttcctgata ttcccggtca catcgagagc ccagtcttca ttgctactaatcaggctcag 480 tcacctgaaa cttctgttgc tcaggtagcc cctgttgatt tagacggtatgcaacaggac 540 attgagcaag tttgggagga gctattatcc attcctgagt tacagtgtcttaatattgaa 600 aatgacaagc tggttgagac taccatggtt ccaagtccag aagccaaactgacagaagtt 660 gacaattatc atttttactc atctataccc tcaatggaaa aagaagtaggtaactgtagt 720 ccacattttc ttaatgcttt tgaggattcc ttcagcagca tcctctccacagaagacccc 780 aaccagttga cagtgaactc attaaattca gatgccacag tcaacacagattttggtgat 840 gaattttatt ctgctttcat agctgagccc agtatcagca acagcatgccctcacctgct 900 actttaagcc attcactctc tgaacttcta aatgggccca ttgatgtttctgatctatca 960 ctttgcaaag ctttcaacca aaaccaccct gaaagcacag cagaattcaatgattctgac 1020 tccggcattt cactaaacac aagtcccagt gtggcatcac cagaacactcagtggaatct 1080 tccagctatg gagacacact acttggcctc agtgattctg aagtggaagagctagatagt 1140 gcccctggaa gtgtcaaaca gaatggtcct aaaacaccag tacattcttctggggatatg 1200 gtacaaccct tgtcaccatc tcaggggcag agcactcacg tgcatgatgcccaatgtgag 1260 aacacaccag agaaagaatt gcctgtaagt cctggtcatc ggaaaaccccattcacaaaa 1320 gacaaacatt caagccgctt ggaggctcat ctcacaagag atgaacttagggcaaaagct 1380 ctccatatcc cattccctgt agaaaaaatc attaacctcc ctgttgttgacttcaacgaa 1440 atgatgtcca aagagcagtt caatgaagct caacttgcat taattcgggatatacgtagg 1500 aggggtaaga ataaagtggc tgctcagaat tgcagaaaaa gaaaactggaaaatatagta 1560 gaactagagc aagatttaga tcatttgaaa gatgaaaaag aaaaattgctcaaagaaaaa 1620 ggagaaaatg acaaaagcct tcacctactg aaaaaacaac tcagcaccttatatctcgaa 1680 gttttcagca tgctacgtga tgaagatgga aaaccttatt ctcctagtgaatactccctg 1740 cagcaaacaa gagatggcaa tgttttcctt gttcccaaaa gtaagaagccagatgttaag 1800 aaaaactaga tttaggagga tttgaccttt tctgagctag tttttttgtactattatact 1860 aaaagctcct actgtgatgt gaaatgctca tactttataa gtaattctatgcaaaatcat 1920 agccaaaact agtatagaaa ataatacgaa actttaaaaa gcattggagtgtcagtatgt 1980 tgaatcagta gtttcacttt aactgtaaac aatttcttag gacaccatttgggctagttt 2040 ctgtgtaagt gtaaatacta caaaaactta tttatactgt tcttatgtcatttgttatat 2100 tcatagattt atatgatgat atgacatctg gctaaaaaga aattattgcaaaactaacca 2160 cgatgtactt ttttataaat actgtatgga caaaaaatgg cattttttataattaaattg 2220 tttagctctg gcaaaaaaaa aaaatttttt aagagctggt actaataaaggattattatg 2280 actgttaaaa aaaaaaaaaa aaaa 2304 196 1350 DNA Homosapiens 196 cgccactgcc acccctccca gactgtggac gggaggatgg agtcgatggccgtcgctacc 60 gacggcgggg agaggccggg ggtcccagcg ggctcaggtc tgtcggcttcccagcgtcgg 120 gcggagctgc gtcggagaaa gctgctcatg aactcggaac agcgcatcaaccggatcatg 180 ggctttcaca ggcccgggag cggcgcggaa gaagaaagtc aaacaaaatcaaagcagcag 240 gacagtgata aactgaactc cctcagcgtt ccttccgttt caaagcgagtagtgctgggt 300 gattcagtca gtacaggaac aactgaccag cagggtggtg tggccgaggtaaaggggacc 360 caactgggag acaaattgga ctcgttcatt aaaccacctg agtgcagtagtgatgtcaac 420 cttgagctcc ggcagcggaa cagaggggac ctgacagcgg actcggtccagaggggttcc 480 cgccatggcc tagagcagta cctttccaga ttcgaagaag caatgaagctaaggaaacag 540 ctgattagtg aaaaacccag tcaagaggat ggaaatacaa cagaagaatttgactctttt 600 cgaatattta gattggtggg atgtgctctt cttgctcttg gagtcagagcttttgtttgc 660 aaatacttgt ccatatttgc tccatttctt actttacaac ttgcgtacatgggattatac 720 aaatattttc ccaagagtga aaagaagata aagacaacag tactaacagctgcacttcta 780 ttgtcgggaa ttcctgccga agtgataaat cgatcaatgg atacctatagcaaaatgggc 840 gaagtcttca cagatctctg tgtctacttt ttcactttta tcttttgtcatgaactgctt 900 gattattggg gctctgaagt accatgaagc ctgtagaact gagaaggagaagcttacgaa 960 aaaaatcctc ttctatattg cagtgtctct aaaggaggca aattggtttacaccttcatg 1020 taattctttt actttagggg ttgtaaagct actttattag atatagaatggcagattctc 1080 tgatttaaaa gggctgagtt tgtattatta ctgatatgaa gaatagagtaccaatgtcat 1140 taattgattt ttcttgttaa tcagaattcc tattctgtac ctttcctctaacttctcaga 1200 tttgtaattc ttcttttcgg gagctgagct agtgctttta ggagaacagataaatgtggt 1260 ctcagccagc cctagagact gcttcttgtg tttgtgtcat tctgtcctgagaaatgaagt 1320 catctgaaaa ataaaaatgc agaaacccaa 1350 197 1659 DNA Homosapiens 197 agcagtacag gcagaagctg gcggctcatg gcttcgtgcc catggggtcaggaacaggga 60 gcgaggagcc cctcggagga gcctccagag gaggaaatcc ccaaggaggatgggatcttg 120 gtgctgagcc gccacaccct gggcctggcc ctgcgggagc accctgccctgctggtggaa 180 ttctatgccc cgtggtgtgg gcactgccag gccctggccc ccgagtacagcaaggcagct 240 gccgtgctcg cggccgagtc aatggtggtc acgctggcca aggtggatgggcccgcgcag 300 cgcgagctgg ctgaggagtt tggtgtgacg gagtacccta cgctcaagttcttccgcaat 360 gggaaccgca cgcaccccga ggagtacaca ggaccacggg acgctgagggcattgccgag 420 tggctgcgac ggcgggtggg gcccagtgcc atgcggctgg aggatgaggcggccgcccag 480 gcgctgatcg gtggccggga cctagtggtc attggcttct tccaggacctgcaggacgag 540 gacgtggcca ccttcttggc cttggcccag gacgccctgg acatgacctttggcctcaca 600 gaccggccgc ggctctttca gcagtttggc ctcaccaagg acactgtggttctcttcaag 660 aagtttgatg aggggcgggc agacttcccc gtggacgagg agcttggcctggacctgggg 720 gatctgtcgc gcttcctggt cacacacagc atgcgcctgg tcacggagttcaacagccag 780 acgtctgcca agatcttcgc ggccaggatc ctcaaccacc tgctgctgtttgtcaaccag 840 acgctggctg cgcaccggga gctcctagcg ggctttgggg aggcagctccccgcttccgg 900 gggcaggtgc tgttcgtggt ggtggacgtg gcggccgaca atgagcacgtgctgcagtac 960 tttggactca aggctgaggc agcccccact ctgcgcttgg tcaaccttgaaaccactaag 1020 aagtatgcgc ctgtggatgg gggccctgtc accgcagcgt ccatcactgctttctgccat 1080 gcagtcctca acggccaagt caagccctat ctcctgagcc aggagataccccctgattgg 1140 gatcagcggc cagttaagac cctcgtgggc aagaattttg agcaggtggcttttgacgaa 1200 accaagaatg tgtttgtcaa gttctatgcc ccgtggtgca cccactgcaaggagatggcc 1260 cctgcctggg aggcattggc tgagaagtac caagaccacg aggacatcatcattgctgag 1320 ctggatgcca cggccaacga gctggatgcc ttcgctgtgc acggcttccctactctcaag 1380 tacttcccag cagggccagg tcggaaggtg attgaataca aaagcaccagggacctggag 1440 actttctcca agttcctgga caacgggggc gtgctgccca cggaggagtccccggaggag 1500 ccagcagccc cgttcccgga gccaccggcc aactccacta tggggtccaaggaggaactg 1560 tagctgcccc cgtgtcaccc ccgccatcac tgctggacag gagccacccccttgggtacc 1620 agagggagct gtgcattgtg aataaagagt gagcttggt 1659 198 1143DNA Homo sapiens 198 ccggggacca tgttgcttcc gaacatcctg ctcaccggtacaccaggggt tggaaaaacc 60 acactaggca aagaacttgc gtcaaaatca ggactgaaatacattaatgt gggtgattta 120 gctcgagaag tctgatcatc ggatatcatg gagtctggcaagacggcttc tcccaagagc 180 atgccgaaag atgcacagat gatggcacaa atcctgaaggatatggggat tacagaatat 240 gagccaagag ttataaatca gatgttggag tttgccttccgatatgtgac cacaattcta 300 gatgatgcaa aaatttattc aagccatgct aagaaagctactgttgatgc agatgatgtg 360 cgattggcaa tccagtgccg cgctgatcag tcttttacctctcctccccc aagagatttt 420 ttattagata ttgcaaggca aagaaatcaa acccctttgccattgatcaa gccatattca 480 ggtcctaggt tgccacctga tagatactgc ttaacagctccaaactatag gctgaaatct 540 ttacagaaaa aggcatcaac ttctgcggga agaataacagtcccgcggtt aagtgttggt 600 tcagttacta gcagaccaag tactcccaca ctaggcacaccaaccccaca gaccatgtct 660 gtttcaacta aagtagggac tcccatgtcc ctcacaggtcaaaggtttac agtacagatg 720 cctacttctc agtctccagc tgtaaaagct tcaattcctgcaacctcagc agttcagaat 780 gttctgatta atccatcatt aatcgggtcc aaaaacattcttattaccac taatatgatg 840 tcatcacaaa atactgccaa tgaatcatca aatgcattgaaaagaaaacg tgaagatgat 900 gatgatgacg atgatgatga tgatgactat gataatctgtaatctagcct tgctgaatgt 960 aacatgtata cttggtcttg aattcattgt actgatattaaacatgcatg ctggatgttt 1020 tcaagttgtg ttttagaaaa ctaataataa tgagtaaacacagttaccat acttttcaat 1080 tgaaatgaag gtttttcatc agccttaaaa gtgtaagaaaaataaagttg tcattcattc 1140 gat 1143 199 1556 DNA Homo sapiens 199ccaaattatt gtatctcaca gtgtggggaa aaggaagaga gatcagattg ttactgtgtc 60tgtgtagaaa gaagtagaca taggagactc cattttgtta tgtactaaga aaaattcttc 120tgccttgaga ttctgttaat ctataacctt accccccaac cccgtgctct ctgaaacatg 180tgctgtgtcc tctcagaatt gcctgttttt tgtgctcctc cgagctcgct gttcgtccgg 240gttttttacg ttttaatttc caggacttga actgccatgt cctctgaaga aggaaagctc 300ttcgtgggag ggctcaactt taacaccgac gagcaggcac tggaagacca cttcagcagt 360ttcggaccta tctctgaggt ggtcgttgtc aaggaccggg agactcagcg gtccaggggt 420tttggtttca tcaccttcac caacccagag catgcttcag ttgccatgag agccatgaac 480ggagagtctc tggatggtcg tcagatccgt gtggatcatg caggcaagtc tgctcgggga 540accagaggag gtggctttgg ggcccatggg cgtggtcgca gctactctag aggtggtggg 600gaccagggct atgggagtgg caggtattat gacagtcgac ctggagggta tggatatgga 660tatggacgtt ccagagacta taatggcaga aaccagggtg gttatgaccg ctactcagga 720ggaaattaca gagacaatta tgacaactga aatgagacat gcacataata tagatacaca 780aggaataatt tctgatccag gatcgtcctt ccaaatggct gtatttataa aggtttttgg 840agctgcactg aagcatctta ttttatagta tatcaacctt ttgtttttaa attgacctgc 900caaggtagct gaagaccttt tagacagttc ccatcttttt ttttaaattt tttctgccta 960tttaaagaca aattatggga cgtttgtaga acctgagtat ttttcttttt accagttttt 1020tagtttgagc tcttaggttt attggagcta gcaataattg gttctggcaa gtttggccag 1080actgacttca aaaaattaat gtgtatccag ggacatttta aaacctgtac acagtgttta 1140ttgtggttag gaagcaattt cccaatgtac ctataagaaa tgtgcatcaa gccagcctga 1200ccaacatggt gaaaccccat ctgtactaaa cataaaaaaa ttagcctggc atggtggtgt 1260acgcctgtaa tcccagtgac ttgggaggct gaggcaggag aatcgcttga acccgggagg 1320cggaggttgc agtgagctaa gatcgcgcca ctgtactcca gcctggacaa cagcgagagc 1380tccatctcaa aaaaaaaagg aaatgtgtat caagaacatg attatccagc ggtattttct 1440aattcagatc atcaaactga ttatatagaa gagttggctt taaaatgttt gcaaatgtcg 1500atgttgagaa tggtatttct tcagttttat tttaggattt ctatagtttg atgatc 1556 2002129 DNA Homo sapiens 200 ggcgctttgt gttctcatcg gagctgcatg ggaagtctgcgtacagcaaa gtgacctgca 60 tgcctcacct tatggaaagg atggtgggct ctggcctcctgtggctggcc ttggtctcct 120 gcattctgac ccaggcatct gcagtgcagc gaggttatggaaaccccatt gaagccagtt 180 cgtatgggct ggacctggac tgcggagctc ctggcaccccagaggctcat gtctgttttg 240 acccctgtca gaattacacc ctcctggatg aacccttccgaagcacagag aactcagcag 300 ggtcccaggg gtgcgataaa aacatgagcg gctggtaccgctttgtaggg gaaggaggag 360 taaggatgtc ggagacctgt gtccaggtgc accgatgccagacagacgct cccatgtggc 420 tgaatgggac ccaccctgcc cttggggatg gcatcaccaaccacactgcc tgtgcccatt 480 ggagtggcaa ctgctgtttc tggaaaacag aggtgctggtgaaggcctgc ccaggcgggt 540 accatgtgta ccggttggaa ggcactccct ggtgtaatctgagatactgc acagacccat 600 ccactgtgga ggacaagtgt gagaaggcct gccgccccgaggaggagtgc cttgccctca 660 acagcacctg gggctgtttc tgcagacagg acctcaatagttctgatgtc cacagtttgc 720 agcctcagct agactgtggg cccagggaga tcaaggtgaaggtggacaaa tgtttgctgg 780 gaggcctggg tttgggggag gaggtcattg cctacctgcgagacccaaac tgcagcagca 840 tcttgcagac agaggagagg aactgggtat ctgtgaccagccccgtccag gctagtgcct 900 gcaggaacat tctggagaga aatcaaaccc atgccatctacaaaaacacc ctctccttgg 960 tcaatgattt catcatcaga gacaccatcc tcaacatcaacttccaatgt gcctacccac 1020 tggacatgaa agtcagcctc caagctgcct tgcagcccattgtaagttcc ctgaacgtca 1080 gtgtggacgg gaatggagag ttcattgtca ggatggccctcttccaagac cagaactaca 1140 cgaatcctta cgaaggggat gcagttgaac tgtctgttgagtccgtgctg tatgtgggtg 1200 ccatcttgga acaaggggac acctcccggt ttaacctggtgttgaggaac tgctatgcca 1260 cccccactga agacaaggct gaccttgtga agtatttcatcatcagaaac agctgctcaa 1320 atcagcgtga ttccaccatc cacgtggagg agaatgggcagtcctcggaa agccggttct 1380 cagttcagat gttcatgttt gctggacatt atgacctagttttcctgcat tgtgagattc 1440 atctctgtga ttctcttaat gaacagtgcc agccttcttgctcaagaagt caagtccgca 1500 gtgaagtacc ggccatcgac ctagcccggg ttctagatttggggcccatc actcggagag 1560 gtgcacagtc tcccggtgtc atgaatggaa cccctagcactgcagggttc ctggtggcct 1620 ggcctatggt cctcctgact gtcctcctgg cttggctgttctgagagctc cgctgagcat 1680 ctggccttga agtttgtgtt cttccctctg gcaatggctcccttcagcac ttctgctttc 1740 cactccaatt cacacaggct tggtattaac agaatcaaggccaggctagg ttaggaaaag 1800 ggaagagctt tcaccttctt tggggctctc ggctgggcgcagtggctcat gcctgtaatc 1860 ccagcatttt gggaggctga ggcaggtgga tcacctgaggtcagcagttc aaaatcagcc 1920 tggccaaaat gctgaaactc cgtctctact aaaaatacaaaaattagcca ggcatggtgg 1980 caggcgcctg taatcccagc tactcgggag gccaaggcaggagaattgct cgaactcagg 2040 gggtggaggt tgcagtgagt tgagattgtg ccattgcactccagcctggg caacagagca 2100 agactctgtc tcaggaaaaa aaaaaaaaa 2129 201 1496DNA Homo sapiens 201 gcacgaggcc tgcactttgt caagtttgcc atcgacagtgaccagctcca tcagctctgg 60 gagaaggacc agctcaacat ggccaagaac acctggcccattctgaaggg ctttcaggag 120 gggcccctca acttcgctcc caccttcaag tttgatgtgggtaccaacaa atacgatacc 180 agtgccaaga aacggaagcc agcttggaca gaccgtatcctatggaaggt caaggctcca 240 ggtgggggtc ccagcccctc aggacggaag agccaccgactccaggtgac gcagcacagc 300 taccgcagcc acatggaata cacagtcagc gaccacaagcctgtggctgc ccagttcctc 360 ctgcagtttg ccttcaggga cgacatgcca ctggtgcggctggaggtggc agatgagtgg 420 gtgcggcccg agcaggcggt ggtgaggtac cgcatggaaacagtgttcgc ccgcagctcc 480 tgggactgga tcggcttata ccgggtgggt ttccgccattgcaaggacta tgtggcttat 540 gtctgggcca aacatgaaga tgtggatggg aatacctaccaggtaacatt cagtgaggaa 600 tcactgccca agggccatgg agacttcatc ctgggctactatagtcacaa ccacagcatc 660 ctcatcggca tcactgaacc cttccagatc tcgctgccttcctcggagtt ggccagcagc 720 agcacagaca gctcaggcac cagctcagag ggagaggatgacagcacact ggagctcctt 780 gcacccaagt cccgcagccc cagtcctggc aagtccaagcgacaccgcag ccgcagcccg 840 ggactggcca ggttccctgg gcttgcccta cggccctcatcccgtgaacg ccgtggtgcc 900 agccgtagcc cctcacccca gagccgccgc ctgtcccgagtggctcctga caggagcagt 960 aatggcagca gccggggcag tagtgaagag gggccctctgggttgcctgg cccctgggcc 1020 ttcccaccag ctgtgcctcg aagcctgggc ctgttgcccgccttgcgcct agagactgta 1080 gaccctggtg gtggtggctc ctggggacct gatcgggaggccctggcgcc caacagcctg 1140 tctcctagtc cccagggcca tcgggggctg gaggaagggggcctggggcc ctgagggtgg 1200 ggtaggcaga tgggccaagg tgaccaccat tctgcctcaatcttttgcaa gcccacctgc 1260 ctctctcctg ctgctcctcc agctgtatct gcacctgcctctctgtcctg gccaggggtg 1320 gacaactggg gtcccccaaa actcagtcct ggcacctcaactgtgacaat cagcaaagcc 1380 ccacccaggc ccccatctgg gatgatggga gagctctggcagatgtccca atcctggagg 1440 tcatccatta ggaattaaat tctccagcct caaaaaaaaaaaaaaaaaaa aaaaaa 1496 202 3490 DNA Homo sapiens 202 gcggcgcggagcgggcgtgc tgagccccgg ccgccggccc ggcatgggcg tctcccgcgg 60 gccctccgccggccggggct agggccggat ggagccgcgg gacggtagcc ccgaggcccg 120 gagcagcgactccgagtcgg cttccgcctc gtccagcggc tccgagcgcg acgccggtcc 180 cgagccggacaaggcgccgc ggcgactcaa caagcggcgc ttcccggggc tgcggctctt 240 cgggcacaggaaagccatca ccaagtcggg cctccagcac ctggcccccc ctccgcccac 300 ccctggggccccgtgcagcg agtcagagcg gcagatccgg agtacagtgg actggagcga 360 gtcagcgacatatggggagc acatctggtt cgagaccaac gtgtccgggg acttctgcta 420 cgttggggagcagtactgtg tagccaggat gctgaagtca gtgtctcgaa gaaagtgcgc 480 agcctgcaagattgtggtgc acacgccctg catcgagcag ctggagaaga taaatttccg 540 ctgtaagccgtccttccgtg aatcaggctc caggaatgtc cgcgagccaa cctttgtacg 600 gcaccactgggtacacagac gacgccagga cggcaagtgt cggcactgtg ggaagggatt 660 ccagcagaagttcaccttcc acagcaagga gattgtggcc atcagctgct cgtggtgcaa 720 gcaggcataccacagcaagg tgtcctgctt catgctgcag cagatcgagg agccgtgctc 780 gctgggggtccacgcagccg tggtcatccc gcccacctgg atcctccgcg cccggaggcc 840 ccagaatactctgaaagcaa gcaagaagaa gaagagggca tccttcaaga ggaagtccag 900 caagaaagggcctgaggagg gccgctggag acccttcatc atcaggccca ccccctcccc 960 gctcatgaagcccctgctgg tgtttgtgaa ccccaagagt gggggcaacc agggtgcaaa 1020 gatcatccagtctttcctct ggtatctcaa tccccgacaa gtcttcgacc tgagccaggg 1080 agggcccaaggaggcgctgg agatgtaccg caaagtgcac aacctgcgga tcctggcgtg 1140 cgggggcgacggcacggtgg gctggatcct ctccaccctg gaccagctac gcctgaagcc 1200 gccaccccctgttgccatcc tgcccctggg tactggcaac gacttggccc gaaccctcaa 1260 ctggggtgggggctacacag atgagcctgt gtccaagatc ctctcccacg tggaggaggg 1320 gaacgtggtacagctggacc gctgggacct ccacgctgag cccaaccccg aggcagggcc 1380 tgaggaccgagatgaaggcg ccaccgaccg gttgcccctg gatgtcttca acaactactt 1440 cagcctgggctttgacgccc acgtcaccct ggagttccac gagtctcgag aggccaaccc 1500 agagaaattcaacagccgct ttcggaataa gatgttctac gccgggacag ctttctctga 1560 cttcctgatgggcagctcca aggacctggc caagcacatc cgagtggtgt gtgatggaat 1620 ggacttgactcccaagatcc aggacctgaa accccagtgt gttgttttcc tgaacatccc 1680 caggtactgtgcgggcacca tgccctgggg ccaccctggg gagcaccacg actttgagcc 1740 ccagcggcatgacgacggct acctcgaggt cattggcttc accatgacgt cgttggccgc 1800 gctgcaggtgggcggacacg gcgagcggct gacgcagtgt cgcgaggtgg tgctcaccac 1860 atccaaggccatcccggtgc aggtggatgg cgagccctgc aagcttgcag cctcacgcat 1920 ccgcatcgccctgcgcaacc aggccaccat ggtgcagaag gccaagcggc ggagcgccgc 1980 ccccctgcacagcgaccagc agccggtgcc agagcagttg cgcatccagg tgagtcgcgt 2040 cagcatgcacgactatgagg ccctgcacta cgacaaggag cagctcaagg aggcctctgt 2100 gccgctgggcactgtggtgg tcccaggaga cagtgaccta gagctctgcc gtgcccacat 2160 tgagagactccagcaggagc ccgatggtgc tggagccaag tccccgacat gccagaaact 2220 gtcccccaagtggtgcttcc tggacgccac cactgccagc cgcttctaca ggatcgaccg 2280 agcccaggagcacctcaact atgtgactga gatcgcacag gatgagattt atatcctgga 2340 ccctgagctgctgggggcat cggcccggcc tgacctccca acccccactt cccctctccc 2400 cacctcaccctgctcaccca cgccccggtc actgcaaggg gatgctgcac cccctcaagg 2460 tgaagagctgattgaggctg ccaagaggaa cgacttctgt aagctccagg agctgcaccg 2520 agctgggggcgacctcatgc accgagacga gcagagtcgc acgctcctgc accacgcagt 2580 cagcactggcagcaaggatg tggtccgcta cctgctggac cacgcccccc cagagatcct 2640 tgatgcggtggaggaaaacg gggagacctg tttgcaccaa gcagcggccc tgggccagcg 2700 caccatctgccactacatcg tggaggccgg ggcctcgctc atgaagacag accagcaggg 2760 cgacactccccggcagcggg ctgagaaggc tcaggacacc gagctggccg cctacctgga 2820 gaaccggcagcactaccaga tgatccagcg ggaggaccag gagacggctg tgtagcgggc 2880 cgcccacgggcagcaggagg gacaatgcgg ccaggggacg agcgccttcc ttgcccacct 2940 cactgccacattccagtggg acggccacgg ggggacctag gccccaggga aagagcccca 3000 tgccgccccctaaggagccg cccagaccta gggctggact caggagctgg gggggcctca 3060 cctgttcccctgaggacccc gccggacccg gaggctcaca gggaacaaga cacggctggg 3120 ttggatatgcctttgccggg gttctggggc agggcgctcc ctggccgcag cagatgccct 3180 cccaggagtggaggggctgg agagggggag gccttcggga agaggcttcc tgggccccct 3240 ggtcttcggccgggtcccca gcccccgctc ctgccccacc ccacctcctc cgggcttcct 3300 cccggaaactcagcgcctgc tgcacttgcc tgccctgcct tgcttggcac ccgctccggc 3360 gaccctccccgctcccctgt catttcatcg cggactgtgc ggcctggggg tggggggcgg 3420 gactctcacggtgacatgtt tacagctggg tgtgactcag taaagtggat ttttttttct 3480 ttaaaaaaaa3490 203 5767 DNA Homo sapiens 203 gagggaggag agttcacttt tacttcagtgtcagcgcgcg gcggccgtgg ctggctctgg 60 cgagagagca ccgagggagt gggtcgcagatcttcgggcg gctaggggaa atcggcgaga 120 ggcgggatcc gagcgcgccg gcggggcgcagagcccgcga gcctggccag cgagggtagc 180 cgcggggggc gcgccccggg cgggcccccggagacgcgca ggatgccaca cgaagagctg 240 ccgtcgctgc agagaccccg ctatggctctattgtggacg atgaaaggct ctctgcagag 300 gagatggatg agaggaggcg gcagaacattgcttatgaat atctgtgcca cttagaggaa 360 gccaaaaggt ggatggaagt ttgcttagttgaagaattgc caccaaccac tgaattggaa 420 gaagggctcc ggaatggagt ttaccttgcaaagttagcca agttctttgc cccgaaaatg 480 gtatcagaga aaaagatcta tgatgtggaacaaacacgtt ataagaagtc tggccttcat 540 tttcgacaca cagataatac cgtccagtggttaagagcga tggagtctat tggtctaccc 600 aagatatttt atccagaaac aacagatgtctatgatcgga aaaacatacc aagaatgata 660 tattgcattc acgcactgag tttgtatctgttcaaactag gaatagcacc ccagatccag 720 gatttgttgg gcaaagtaga cttcacagaggaggaaatca gtaatatgag aaaagaactt 780 gagaaatatg gaatacagat gccatctttcagcaaaatag gtggtattct ggccaatgaa 840 ctgtccgtgg atgaagctgc attacatgctgcagttatag ccattaatga agcagttgaa 900 aaaggaatag cagagcaaac cgttgtaacactaagaaacc caaatgcggt tttaacttta 960 gtggatgaca accttgcacc agaatatcagaaagaactct gggatgccaa aaagaaaaaa 1020 gaggaaaatg caagactgaa gaatagctgtatttcagaag aagaaagaga tgcttatgaa 1080 gaactgctga cacaagcaga aatccaaggcaatattaata aagtcaacag gcaggctgca 1140 gtggaccata tcaatgctgt cattccggaaggtgaccccg agaatacgct gcttgcactg 1200 aagaaaccag aggcccagct gcctgctgtttatccctttg ctgctgccat gtatcagaac 1260 gaacttttca acctccagaa acagaacaccatgaactact tggcccacga ggagcttttg 1320 attgctgtgg aaatgttgtc tgctgttgctttactaaacc aggccttgga aagcaacgat 1380 cttgtgtctg tgcagaatca actcagaagccccgcaatag gcttaaacaa tctggacaag 1440 gcatatgtgg aacgttatgc aaacacactactctctgtta aactagaagt tttatcccaa 1500 gggcaagata acttaagctg gaatgaaattcagaattgta ttgatatggt taatgctcaa 1560 attcaagaag aaaatgaccg agttgtagctgtagggtaca tcaatgaagc tattgatgaa 1620 gggaatcctt tgaggacttt agaaactttgctcctaccta ctgcgaatat tagtgatgtg 1680 gacccagccc atgcccagca ctaccaggatgttttatacc atgctaaatc acagaaactc 1740 ggagactctg agagtgtttc caaagtgctttggctggatg agatacagca agccgtcgat 1800 gaggccaacg tggacgagga cagagcaaaacaatgggtta ctctggtggt tgatgttaat 1860 cagtgtttgg aaggaaaaaa atcaagtgatattttgtctg tattgaagtc ttccacttct 1920 aatgcaaatg acataatccc ggagtgtgctgacaaatact atgatgccct tgtgaaggca 1980 aaagagctca aatctgaaag agtgtctagtgacggttcat ggctcaaact caacctgcac 2040 aaaaaatatg actactatta caacactgattcaaaagaga gttcctgggt cacacctgaa 2100 tcatgcttct ataaagaatc atggctcacaggaaaagaaa tcgaggacat tattgaggaa 2160 gtcacagtag gttacattcg tgagaatatatggtctgctt cagaagagtt gcttcttcgc 2220 tttcaagcca caagctcagg acccatccttagggaagagt ttgaagctag aaaatcattt 2280 ttgcatgaac aagaagagaa tgtggtcaaaatacaggctt tttggaaagg atataaacaa 2340 cggaaggagt atatgcacag gcggcaaacgttcattgata atactgattc tgttgtgaag 2400 attcagtcct ggttccgaat ggcaactgcaagaaagagct atctttcaag actacagtat 2460 ttcagagatc ataataatga aattgtgaaaatacagtcac tgttgagagc gaacaaagct 2520 agagatgact acaaaacatt ggttggctctgaaaacccac cattaacagt aattcgcaaa 2580 tttgtatacc tgctggacca aagtgatttggatttccagg aggaactaga ggttgcacga 2640 ttaagggaag aagtagtgac caagatcagggccaatcaac agctggaaaa agacctgaac 2700 ctgatggaca tcaagattgg actgctggtgaagaacagga tcacactaga ggatgtaatt 2760 tcacacagta aaaagctgaa caagaaaaaaggaggagaaa tggaaatact gaataacacc 2820 gacaaccaag gaataaaaag tttgagtaaggagaggagaa aaacactaga aacatatcag 2880 cagctgtttt accttttaca gaccaaccctttatacttgg ctaagctgat tttccagatg 2940 ccacagaaca agtccactaa atttatggatactgttattt tcacactata taattatgcc 3000 tctaatcagc gagaagaata tctacttctcaagcttttta aaactgctct ggaggaagaa 3060 ataaaatcaa aagtggacca ggtacaggacatagttactg gtaaccctac agtcatcaag 3120 atggtcgtca gcttcaatag aggtgcccggggacagaaca ccctgcgcca actcctggct 3180 ccagtggtaa aagagatcat cgacgacaagtcgctgatta tcaacacaaa ccctgtagag 3240 gtgtacaagg cttgggtgaa ccaactagaaacacagactg gagaggccag caagttgcct 3300 tatgatgtga ccacagaaca agctctaacatacccagaag tgaaaaataa actggaggct 3360 tccattgaga acctgagaag ggtcaccgacaaagtcctga attctatcat ttcttccctt 3420 gatctactgc cttatggatt gaggtatatagccaaagtac tgaagaattc gatccatgag 3480 aaattccccg atgcaacaga agatgagctattaaagattg ttggaaacct cctgtactat 3540 cggtacatga atccagccat tgtagctccagatggctttg atatcatcga catgacagct 3600 ggaggtcaga taaattctga ccaaaggagaaacttaggat cagtggccaa ggttcttcag 3660 cacgcagcct ccaacaagct gtttgaaggagaaaatgagc atctctcatc tatgaacaat 3720 tatttatcag agacgtatca ggaattcaggaaatatttca aagaagcatg taatgtccct 3780 gagccagaag agaagtttaa tatggacaaatacacagacc tggtgacagt cagcaaacca 3840 gtcatttata tttcaattga agaaatcatcagcacacact cactcctgtt ggaacaccag 3900 gatgcaattg cccctgagaa aaatgacttactgagtgaat tgctggggtc gctgggagag 3960 gtgccaaccg tggaatcttt tcttggggaaggagcagttg accccaatga ccctaacaag 4020 gcaaatacac taagtcagct ttcaaagaccgagatttctc ttgtcttgac aagcaaatat 4080 gacatagagg acggtgaagc tatagatagccgaagcctca tgataaagac caagaagctg 4140 ataattgatg tgatccggaa ccagccagggaacacattga cagaaatctt agagacacca 4200 gcaactgcgc aacaggaggt agaccatgccacggacatgg tgagccgtgc aatgatagat 4260 tccaggactc cagaagaaat gaagcatagccaatctatga ttgaagatgc acagctgcct 4320 cttgagcaga agaagaggaa aatccagaggaatcttcgga cgttggaaca gactggacac 4380 gtgtcatccg aaaataaata ccaagacattctcaatgaga ttgccaagga tattcgaaat 4440 caaagaatct atcgtaagct tcgaaaagctgaattggcaa aacttcagca gaccctgaat 4500 gcacttaaca agaaggcagc attttatgaagagcaaatca attattatga cacctacata 4560 aagacttgtt tagacaactt aaaaagaaaaaatactcgga gatcaattaa actagatgga 4620 aaaggagaac ccaaaggggc gaagagagcgaagccagtga agtacactgc agcaaagctg 4680 catgagaaag gtgtcctgct agatatagatgatcttcaaa caaaccagtt taagaatgtt 4740 acatttgata tcatagctac tgaagatgtaggcattttcg atgtaagatc aaaattcctt 4800 ggtgttgaga tggaaaaggt gcaactcaatattcaggatt tacttcagat gcaatatgaa 4860 ggagtagctg taatgaaaat gtttgataaggttaaagtga atgtaaacct tctcatatac 4920 ctgctgaaca agaagttcta tggaaagtgaagtgcctaca gaaatttctt ggattctgta 4980 tcatctggat taggaaatga atttgtttaatatttttgtt tttaaacatg attgaaatca 5040 ctgcttataa atgtgtgatt ttttttaaatgaccaaaact gttctgaaga atgtacccag 5100 gtgccttttt gctaatttga tactataatagaatgagaca taaaatgaat taatggaaac 5160 atatccacac tgtactgtga tataggtactctgatttaaa actttggaca tcctgtgatc 5220 tgttttaaag ttggggggtg ggaaatttagctgactaggg acaaacatgt aaacctattt 5280 tcctatgaaa aaagttttaa atgtcccacttgaataacgt aattcttcat agttttttta 5340 atctatggat aaatggaaac ctaattatttgtaatgaatt atttagacag ttctaagccc 5400 tgtcttctgg gagttatcaa ttttaaagagaacttttgtg caattcaaat gaagttttta 5460 taagtaattg aaaatgacaa cacaataacactttctgtat aaaagtatat attttatgtg 5520 atttattcct actaaatgaa agtgcactactgcctcatgt aaagactctt gcacgcagag 5580 cctttaagtg actaaggaac aacatagatagtgagcatag tccccacctc cacccctcac 5640 aatttatttg aatacttcaa ttgtgcctctcaattttttg taatgctaaa aaatcagtat 5700 ctagatggtt tttaaatgta ttctctggaaattgttttat gtaaaataaa tgttacttaa 5760 ttccatt 5767 204 1451 DNA Homosapiens 204 tctctctaac cgcgccagtg tgcctccgac tcggaacggc ttccgcggccggggcagcga 60 gggccggggg cggcgggcgg gatgagtgcg gtgtgcggtg gagcggcgcggatgctgcgg 120 acgccgggac gccacggcta cgccgccgag ttctccccgt acctgccgggccgcctggcc 180 tgcgccaccg cgcagcacta cggcatcgcg ggctgtggaa ccctactaatattggatcca 240 gatgaagctg ggctaaggct ttttagaagc tttgactgga atgatggtttgtttgatgtg 300 acttggagtg agaacaacga acatgtcctc atcacctgta gtggcgatggctcgctgcag 360 ctctgggaca ctgccaaagc tgcagggcca ctgcaagtct ataaagaacacgctcaggag 420 gtgtatagtg ttgattggag ccaaaccaga ggtgaacagc ttgtggtgtctggctcatgg 480 gatcaaactg tcaaattgtg ggatccaact gttggaaagt ctctgtgcacctttagaggc 540 catgaaagta ttatttatag cacaatctgg tctccccaca tccctggttgttttgcttca 600 gcctcaggtg atcagactct gagaatatgg gatgtgaagg cagcaggagtaagaatcgtg 660 attcctgcac atcaggcaga aatcttgagt tgtgactggt gtaaatacaatgagaatttg 720 ctggtgaccg gggcggttga ctgtagtttg agaggctggg acttaaggaatgtacgacaa 780 ccagtgtttg aacttcttgg tcatacctat gctattagga gggtgaaattttcaccattt 840 catgcttctg tgctggcctc ttgctcgtat gattttactg taagattctggaacttttca 900 aagcctgact ctcttcttga aacagtggag catcatacag agtttacttgtggtttagac 960 ttcagtcttc agagccccac tcaggtggct gactgttctt gggatgaaacaataaagatc 1020 tatgaccctg cttgtcttac tattcctgct tgagatacac tactttggtcagaaacagag 1080 gatgttggct gaagaactgc ctaacagcaa ataaattaac tatggaaaacatagacatta 1140 tgcttttata tgctattcag atttcaaatc tttccaattt accctggaatcagttttgag 1200 ggagctgata aagactttag ctgactcgtt aagcctgata cataagccatatttaaaatt 1260 ctaagaaata attaatgtta tgatatatct tgtagtatct attaaaatgtagtctctggg 1320 tcataaaatg gattaaaata tgggagatca gtaggttata cgtatatagatagtgatata 1380 tttcattttt aatttgtcat ttttgatgta aaatataatc actgctgtgataaataaact 1440 atctattgat c 1451 205 1675 DNA Homo sapiens 205gtgagacaga gacaaatgaa cccccctcta aagtcattta actaatagcc agcacatccc 60ttccccaaac tgtcaattga aatcttaact gaaagtttta ctgaataata ccaagctaat 120tgctgttggg cacacctgga tggctttgca cctggtgttg aacctgctga agcaggtgga 180tgctcaagat tacgtgcaag gaatccctcc catctggtac taaaatttca gtgtgttctg 240agtgtctttt aaaccaaaat ggaaatacag atacagggct gtagtattca gtaatgtgtc 300tgctccttgt tgggcagaca ccagcggtgt gcagggagag accaagtacc atctttatct 360acacttgggc tggcttgtgg agaagggctg ctttttttca gtcctacatt ccttcatttt 420ttttttcatt cttgaattca ttgttttgtg ggatctaaga cccaggggtc atttgagagg 480tttgacagta tcttttctga ccagttgcca catgacttgc ttgaccctga gcctgtggaa 540atggcatagg gaccagtcta ctacccactg ggcctggtgt gtagaggggg agagggtagc 600aaggtgcttc tctacgccca tgacttggga gcaggtcttg gcctccttca tgagagtcta 660gtgccatgtc ctgtcccatg atctggaccc tgggactgtc ttggcatctt aactgcagtt 720tcaatgaggc agagggcaaa gagagaccaa gatcagaggg gttcattata cccctggcta 780gagaacccag ctactgacat gcaagcagct tggggctggc tggacacagg tactaggccc 840attgtttcca ggtgaagctt tcatcacaga acagtgttgt ctccacctgg ccttagatgg 900cacgccatga ttcgggcctg gatagactgc ctgcgtcctt accactgatc tggccaagaa 960tgaggccctc ccaacacttt cactccctct ccaagccttg atgggacctc cacttattta 1020ggcctcatgt gctttgaaga agctttgaga gccaatgtgt cttccacggg tctctttttt 1080gctacaagta atcagcccca tgtgttctct taaactgaga attgcacctg ggcaattcct 1140gttttctaag gtggtctctg ctgctattta acaacccaga gtaggcctct gtgaggcttc 1200agtggcctca gaaaccagag ggtccagata gggggcctgc ttgggccctc tgctgccaac 1260tgctcaaacc tgctttagct ccagccactt gtggcaaaca acctcgtttc cttacaaatt 1320ccagcatgtg actttggtgc cgttacttgt gaaaaatcta ttctgttgtc tttgatgtgt 1380ccaagaaaat tcgtgtagtt tacgtaaaaa tatctgactc acaagaaagc caactgtatg 1440tcttgtgatg ggacagttca taatgtagtt gctagaccac tttacaaatt gttcttgtca 1500ccagatgtgt tcagacattg ctgtgcaatt gttggggagg gtagggggaa aggcgagagg 1560agatacttat tggtcttttt gtttaatacc ttccccaaga ggggacagtc tggccaactt 1620gctccagtaa tgcaataaag acattgcaat aaagtaaaaa aaaaaaaaaa aaaaa 1675 2061632 DNA Homo sapiens 206 ccgttcctca ggaaaaggat ggaccttctc ttcttctcagatggtccctt ccattcccct 60 gaaacctgca tgagagctcc taacatgttt ctccaatgcaatcaagccct agactccaaa 120 tgtcctccca gctcacctcc atctatgcat ctcatctctggatttggtga tcagactcta 180 tattgacagt aggatctcaa accctgcatc catccttcctccagcaagcc ctgctagcca 240 catgaggaac aagtttccgt gtcttctgcc ttcctcttggggaaaggtgc cttgttgtga 300 tgaattaact cactgttagg gcagggtgga gaatggtactccttccttct cctgtccact 360 gtgggggaag cttggcaggt atattatatt tcatcatttaggaggctggc atgaccagga 420 cttatgggtg ggaggggagc atttttagtg aagcaagaaaggagtttgcc aagaagtgat 480 ctgttttaaa ggtcatattt ggagaaaggg caaggaattgggtctgcttt atttttgggg 540 gtattttgtt tttgttctca cctgctgccc ccccaccccaccaccccagg gataaattgg 600 atataaacac taaatactaa tcagttgaac ttaacatttaataaaaagaa agggtgaaat 660 aaactgaaga ccattttaga actagtcagt tctctgcagcaaagggaaca ggagccattt 720 gaaccctctg ggacccctca ccccactgct tcagggtgctaggctgaggg atgtttttcc 780 tcccccttac cgcccatgcc cttgaaagaa aagtcactttttgtggaggg catcattcat 840 tcctgattca caaaccccaa aaacctctgg tgggagataggaagataggg cgtgggcctg 900 ggccttaacc tcaatcttgt gtctgcctca gtcttttctgactggccctg aagttgtcag 960 tggctctttc tgtccttcag cccctggaag gtgctccaggataacaaaga agggcaggtt 1020 gaagcccctc atggaaggag ctggctttgt ggggctgcaaaggactttta agtcctgcct 1080 gtactgaagt tcacagccca cctgactgag cagactcttcctgttccttt ctctaccacc 1140 cttgccttcc caggactgca cggtttaaca cagcagagtacagaagggtg aagaagtgag 1200 cagaggctta tgaagatatt cagatactct tctatgccaggaagcacaaa gactttgttg 1260 agatttgcct cagttcagta gatcttcctt ggcagccagccataggttgt ttctttgtct 1320 tccgggtcct aaagagcaca gagaaaatgg aggtccccagtctaggtagg aagctgattg 1380 gatgaggact tctttttttc cgacagcagg atggggctcttgggctccac acaccagatg 1440 ctttggtttt ctacaactgt tgctatgtgt agagggtgctcagagcgtgg catgagagca 1500 aggagaccat ggctactctt tgaaatggat ggggaaaattagcttaaaaa tttaatcacg 1560 agattgcgcc actgcactcc agcctgggcg acagagccagactccgtctc aaaaaaaaaa 1620 aaaaaaaaaa aa 1632 207 2977 DNA Homo sapiens207 ccgaatgtga ccgcctcccg ctccctcacc cgccgcgggg aggaggagcg ggcgagaagc 60tgccgccgaa cgacaggacg ttggggcggc ctggctccct caggtttaag aattgtttaa 120gctgcatcaa tggagcacat acagggagct tggaagacga tcagcaatgg ttttggattc 180aaagatgccg tgtttgatgg ctccagctgc atctctccta caatagttca gcagtttggc 240tatcagcgcc gggcatcaga tgatggcaaa ctcacagatc cttctaagac aagcaacact 300atccgtgttt tcttgccgaa caagcaaaga acagtggtca atgtgcgaaa tggaatgagc 360ttgcatgact gccttatgaa agcactcaag gtgaggggcc tgcaaccaga gtgctgtgca 420gtgttcagac ttctccacga acacaaaggt aaaaaagcac gcttagattg gaatactgat 480gctgcgtctt tgattggaga agaacttcaa gtagatttcc tggatcatgt tcccctcaca 540acacacaact ttgctcggaa gacgttcctg aagcttgcct tctgtgacat ctgtcagaaa 600ttcctgctca atggatttcg atgtcagact tgtggctaca aatttcatga gcactgtagc 660accaaagtac ctactatgtg tgtggactgg agtaacatca gacaactctt attgtttcca 720aattccacta ttggtgatag tggagtccca gcactacctt ctttgactat gcgtcgtatg 780cgagagtctg tttccaggat gcctgttagt tctcagcaca gatattctac acctcacgcc 840ttcaccttta acacctccag tccctcatct gaaggttccc tctcccagag gcagaggtcg 900acatccacac ctaatgtcca catggtcagc accacgctgc ctgtggacag caggatgatt 960gaggatgcaa ttcgaagtca cagcgaatca gcctcacctt cagccctgtc cagtagcccc 1020aacaatctga gcccaacagg ctggtcacag ccgaaaaccc ccgtgccagc acaaagagag 1080cgggcaccag tatctgggac ccaggagaaa aacaaaatta ggcctcgtgg acagagagat 1140tcaagctatt attgggaaat agaagccagt gaagtgatgc tgtccactcg gattgggtca 1200ggctcttttg gaactgttta taagggtaaa tggcacggag atgttgcagt aaagatccta 1260aaggttgtcg acccaacccc agagcaattc caggccttca ggaatgaggt ggctgttctg 1320cgcaaaacac ggcatgtgaa cattctgctt ttcatggggt acatgacaaa ggacaacctg 1380gcaattgtga cccagtggtg cgagggcagc agcctctaca aacacctgca tgtccaggag 1440accaagtttc agatgttcca gctaattgac attgcccggc agacggctca gggaatggac 1500tatttgcatg caaagaacat catccataga gacatgaaat ccaacaatat atttctccat 1560gaaggcttaa cagtgaaaat tggagatttt ggtttggcaa cagtaaagtc acgctggagt 1620ggttctcagc aggttgaaca acctactggc tctgtcctct ggatggcccc agaggtgatc 1680cgaatgcagg ataacaaccc attcagtttc cagtcggatg tctactccta tggcatcgta 1740ttgtatgaac tgatgacggg ggagcttcct tattctcaca tcaacaaccg agatcagatc 1800atcttcatgg tgggccgagg atatgcctcc ccagatctta gtaagctata taagaactgc 1860cccaaagcaa tgaagaggct ggtagctgac tgtgtgaaga aagtaaagga agagaggcct 1920ctttttcccc agatcctgtc ttccattgag ctgctccaac actctctacc gaagatcaac 1980cggagcgctt ccgagccatc cttgcatcgg gcagcccaca ctgaggatat caatgcttgc 2040acgctgacca cgtccccgag gctgcctgtc ttctagttga ctttgcacct gtcttcaggc 2100tgccagggga ggaggagaag ccagcaggca ccacttttct gctccctttc tccagaggca 2160gaacacatgt tttcagagaa gctctgctaa ggaccttcta gactgctcac agggccttaa 2220cttcatgttg ccttcttttc tatccctttg ggccctggga gaaggaagcc atttgcagtg 2280ctggtgtgtc ctgctccctc cccacattcc ccatgctcaa ggcccagcct tctgtagatg 2340cgcaagtgga tgttgatggt agtacaaaaa gcaggggccc agccccagct gttggctaca 2400tgagtattta gaggaagtaa ggtagcaggc agtccagccc tgatgtggag acacatggga 2460ttttggaaat cagcttctgg aggaatgcat gtcacaggcg ggactttctt cagagagtgg 2520tgcagcgcca gacattttgc acataaggca ccaaacagcc caggactgcc gagactctgg 2580ccgcccgaag gagcctgctt tggtactatg gaacttttct taggggacac gtcctccttt 2640cacagcttct aaggtgtcca gtgcattggg atggttttcc aggcaaggca ctcggccaat 2700ccgcatctca gccctctcag gagcagtctt ccatcatgct gaattttgtc ttccaggagc 2760tgcccctatg gggcgggccg cagggccagc ctgtttctct aacaaacaaa caaacaaaca 2820gccttgtttc tctagtcaca tcatgtgtat acaaggaagc caggaataca ggttttcttg 2880atgatttggg ttttaatttt gtttttattg cacctgacaa aatacagtta tctgatggtc 2940cctcaattat gttattttaa taaaataaat taaattt 2977 208 5629 DNA Homo sapiens208 gcgcgaccgt cccgggggtg gggccgggcg cagcggcgag aggaggcgaa ggtggctgcg 60gtagcagcag cgcggcagcc tcggacccag cccggagcgc agggcggccg ctgcaggtcc 120ccgctcccct ccccgtgcgt ccgcccatgg ccgccgccgg gcagctgtgc ttgctctacc 180tgtcggcggg gctcctgtcc cggctcggcg cagccttcaa cttggacact cgggaggaca 240acgtgatccg gaaatatgga gaccccggga gcctcttcgg cttctcgctg gccatgcact 300ggcaactgca gcccgaggac aagcggctgt tgctcgtggg ggccccgcgc ggagaagcgc 360ttccactgca gagagccaac agaacgggag ggctgtacag ctgcgacatc accgcccggg 420ggccatgcac gcggatcgag tttgataacg atgctgaccc cacgtcagaa agcaaggaag 480atcagtggat gggggtcacc gtccagagcc aaggtccagg gggcaaggtc gtgacatgtg 540ctcaccgata tgaaaaaagg cagcatgtta atacgaagca ggaatcccga gacatctttg 600ggcggtgtta tgtcctgagt cagaatctca ggattgaaga cgatatggat gggggagatt 660ggagcttttg tgatgggcga ttgagaggcc atgagaaatt tggctcttgc cagcaaggtg 720tagcagctac ttttactaaa gactttcatt acattgtatt tggagccccg ggtacttata 780actggaaagg gattgttcgt gtagagcaaa agaataacac tttttttgac atgaacatct 840ttgaagatgg gccttatgaa gttggtggag agactgagca tgatgaaagt ctcgttcctg 900ttcctgctaa cagttactta ggtttttctt tggactcagg gaaaggtatt gtttctaaag 960atgagatcac ttttgtatct ggtgctccca gagccaatca cagtggagcc gtggttttgc 1020tgaagagaga catgaagtct gcacatctcc tccctgagca catattcgat ggagaaggtc 1080tggcctcttc atttggctat gatgtggcgg tggtggacct caacaaggat gggtggcaag 1140atatagttat tggagcccca cagtattttg atagagatgg agaagttgga ggtgcagtgt 1200atgtctacat gaaccagcaa ggcagatgga ataatgtgaa gccaattcgt cttaatggaa 1260ccaaagattc tatgtttggc attgcagtaa aaaatattgg agatattaat caagatggct 1320acccagatat tgcagttgga gctccgtatg atgacttggg aaaggttttt atctatcatg 1380gatctgcaaa tggaataaat accaaaccaa cacaggttct caagggtata tcaccttatt 1440ttggatattc aattgctgga aacatggacc ttgatcgaaa ttcctaccct gatgttgctg 1500ttggttccct ctcagattca gtaactattt tcagatcccg gcctgtgatt aatattcaga 1560aaaccatcac agtaactcct aacagaattg acctccgcca gaaaacagcg tgtggggcgc 1620ctagtgggat atgcctccag gttaaatcct gttttgaata tactgctaac cccgctggtt 1680ataatccttc aatatcaatt gtgggcacac ttgaagctga aaaagaaaga agaaaatctg 1740ggctatcctc aagagttcag tttcgaaacc aaggttctga gcccaaatat actcaagaac 1800taactctgaa gaggcagaaa cagaaagtgt gcatggagga aaccctgtgg ctacaggata 1860atatcagaga taaactgcgt cccattccca taactgcctc agtggagatc caagagccaa 1920gctctcgtag gcgagtgaat tcacttccag aagttcttcc aattctgaat tcagatgaac 1980ccaagacagc tcatattgat gttcacttct taaaagaggg atgtggagac gacaatgtat 2040gtaacagcaa ccttaaacta gaatataaat tttgcacccg agaaggaaat caagacaaat 2100tttcttattt accaattcaa aaaggtgtac cagaactagt tctaaaagat cagaaggata 2160ttgctttaga aataacagtg acaaacagcc cttccaaccc aaggaatccc acaaaagatg 2220gcgatgacgc ccatgaggct aaactgattg caacgtttcc agacacttta acctattctg 2280catatagaga actgagggct ttccctgaga aacagttgag ttgtgttgcc aaccagaatg 2340gctcgcaagc tgactgtgag ctcggaaatc cttttaaaag aaattcaaat gtcacttttt 2400atttggtttt aagtacaact gaagtcacct ttgacacccc atatctggat attaatctga 2460agttagaaac aacaagcaat caagataatt tggctccaat tacagctaaa gcaaaagtgg 2520ttattgaact gcttttatcg gtctcgggag ttgctaaacc ttcccaggtg tattttggag 2580gtacagttgt tggcgagcaa gctatgaaat ctgaagatga agtgggaagt ttaatagagt 2640atgaattcag ggtaataaac ttaggtaaac ctcttacaaa cctcggcaca gcaaccttga 2700acattcagtg gccaaaagaa attagcaatg ggaaatggtt gctttatttg gtgaaagtag 2760aatccaaagg attggaaaag gtaacttgtg agccacaaaa ggagataaac tccctgaacc 2820taacggagtc tcacaactca agaaagaaac gggaaattac tgaaaaacag atagatgata 2880acagaaaatt ttctttattt gctgaaagaa aataccagac tcttaactgt agcgtgaacg 2940tgaactgtgt gaacatcaga tgcccgctgc gggggctgga cagcaaggcg tctcttattt 3000tgcgctcgag gttatggaac agcacatttc tagaggaata ttccaaactg aactacttgg 3060acattctcat gcgagccttc attgatgtga ctgctgctgc cgaaaatatc aggctgccaa 3120atgcaggcac tcaggttcga gtgactgtgt ttccctcaaa gactgtagct cagtattcgg 3180gagtaccttg gtggatcatc ctagtggcta ttctcgctgg gatcttgatg cttgctttat 3240tagtgtttat actatggaag tgtggtttct tcaagagaaa taagaaagat cattatgatg 3300ccacatatca caaggctgag atccatgctc agccatctga taaagagagg cttacttctg 3360atgcatagta ttgatctact tctgtaattg tgtggattct ttaaacgctc taggtacgat 3420gacagtgttc cccgatacca tgctgtaagg atccggaaag aagagcgaga gatcaaagat 3480gaaaagtata ttgataacct tgaaaaaaaa cagtggatca caaagtggaa cagaaatgaa 3540agctactcat agcgggggcc taaaaaaaaa aaagcttcac agtacccaaa ctgctttttc 3600caactcagaa attcaatttg gatttaaaag cctgctcaat ccctgaggac tgatttcaga 3660gtgactacac acagtacgaa cctacagttt taactgtgga tattgttacg tagcctaagg 3720ctcctgtttt gcacagccaa atttaaaact gttggaatgg atttttcttt aactgccgta 3780atttaacttt ctgggttgcc tttgtttttg gcgtggctga cttacatcat gtgttgggga 3840agggcctgcc cagttgcact caggtgacat cctccagata gtgtagctga ggaggcacct 3900acactcacct gcactaacag agtggccgtc ctaacctcgg gcctgctgcg cagacgtcca 3960tcacgttagc tgtcccacat cacaagacta tgccattggg gtagttgtgt ttcaacggaa 4020agtgctgtct taaactaaat gtgcaataga aggtgatgtt gccatcctac cgtcttttcc 4080tgtttcctag ctgtgtgaat acctgctcac gtcaaatgca tacaagtttc attctccctt 4140tcactaaaaa cacacaggtg caacagactt gaatgctagt tatacttatt tgtatatggt 4200atttattttt tcttttcttt acaaaccatt ttgttattga ctaacaggcc aaagagtctc 4260cagtttaccc ttcaggttgg tttaatcaat cagaattaga attagagcat gggagggtca 4320tcactatgac ctaaattatt tactgcaaaa agaaaatctt tataaatgta ccagagagag 4380ttgttttaat aacttatcta taaactataa cctctccttc atgacagcct ccaccccaca 4440acccaaaagg tttaagaaat agaattataa ctgtaaagat gtttatttca ggcattggat 4500attttttact ttagaagcct gcataatgtt tctggattta catactgtaa cattcaggaa 4560ttcttggaga agatgggttt attcactgaa ctctagtgcg gtttactcac tgctgcaaat 4620actgtatatt caggacttga aagaaatggt gaatgcctat ggaactagtg gatccaaact 4680gatccagtat aagactactg aatctgctac caaaacagtt aatcagtgag tcgagtgttc 4740tattttttgt tttgtttcct cccctatctg tattcccaaa aattactttg gggctaattt 4800aacaagaact ttaaattgtg ttttaattgt aaaaatggca gggggtggaa ttattactct 4860atacattcaa cagagactga atagatatga aagctgattt tttttaatta ccatgcttca 4920caatgttaag ttatatgggg agcaacagca aacaggtgct aatttgtttt ggatatagta 4980taagcagtgt ctgtgttttg aaagaataga acacagtttg tagtgccact gttgttttgg 5040ggggggcttt ttttcttttt ccggaaaatc cttaaacctt aagatactaa ggacgttgtt 5100ttggttgtac ttggaattct tagtcacaaa atatattttg tttacaaaaa tttctgtaaa 5160acaggttata acagtgttta aagtctcagt ttcttgcttg gggaacttgt gtccctaatg 5220tgttagattg ctagattgct aaggagctga tacttgacag ttttttagac ctgtgttact 5280aaaaaaaaga tgaatgtcgg aaaagggtgt tgggagggtg gtcaacaaag aaacaaagat 5340gttatggtgt ttagacttat ggttgttaaa aatgtcatct caagtcaagt cactggtctg 5400tttgcatttg atacattttt gtactaacta gcattgtaaa attatttcat gattagaaat 5460tacctgtgga tatttgtata aaagtgtgaa ataaattttt tataaaagtg ttcattgttt 5520cgtaacacag cattgtatat gtgaagcaaa ctctaaaatt ataaatgaca acctgaatta 5580tctatttcat caaaaaaaaa aaaaaaaaaa actttatggg cacaactgg 5629 209 1380 DNAHomo sapiens 209 cagcagcatg cgggggttgc tggtgttgag tgtcctgttg ggggctgtctttggcaagga 60 ggactttgtg gggcatcagg tgctccgaat ctctgtagcc gatgaggcccaggtacagaa 120 ggtgaaggag ctggaggacc tggagcacct gcagctggac ttctggcgggggcctgccca 180 ccctggctcc cccatcgacg tccgagtgcc cttccccagc atccaggcggtcaagatctt 240 tctggagtcc cacggcatca gctatgagac catgatcgag gacgtgcagtcgctgctgga 300 cgaggagcag gagcagatgt tcgccttccg gtcccgggcg cgctccaccgacacttttaa 360 ctacgccacc taccacaccc tggaggagat ctatgacttc ctggacctgctggtggcgga 420 gaacccgcac cttgtcagca agatccagat tggcaacacc tatgaagggcgtcccattta 480 tgtgctgaag ttcagcacgg ggggcagtaa gcgtccagcc atctggatcgacacgggcat 540 ccattcccgg gagtgggtca cccaggccag tggggtctgg tttgcaaagaagatcactca 600 agactatggg caggatgcag ctttcaccgc cattctcgac accttggacatcttcctgga 660 gatcgtcacc aaccctgatg gctttgcctt cacgcacagc acgaatcgcatgtggcgcaa 720 gactcggtcc cacacagcag gctccctctg tattggcgtg gaccccaacaggaactggga 780 cgctggcttt gggttgtccg gagccagcag taacccctgc tcggagacttaccacggcaa 840 gtttgccaat tccgaagtgg aggtcaagtc cattgtagac tttgtgaaggaccatgggaa 900 catcaaggcc ttcatctcca tccacagcta ctcccagctc ctcatgtatccctatggcta 960 caaaacagaa ccagtccctg accaggatga gctggatcag ctttccaaggctgctgtgac 1020 agccctggcc tctctctacg ggaccaagtt caactatggc agcatcatcaaggcaattta 1080 tcaagccagt ggaagcacta ttgactggac ctacagccag ggcatcaagtactccttcac 1140 cttcgagctc cgggacactg ggcgctatgg cttcctgctg ccagcctcccagatcatccc 1200 cacagccaag gagacgtggc tggcgcttct gaccatcatg gagcacaccctgaatcaccc 1260 ctactgagct gaccctttga cacccttctt gtcctcctct ctggccccatccaggcaacc 1320 aaataaagtt tgagtgtacc aggaacagaa tcctggggct tgcaaaaaaaaaaaaaaaaa 1380 210 1184 DNA Homo sapiens 210 atctgccacg atgttgctgctcagcctgac cctaagcctg gttctcctcg gctcctcctg 60 gggctgcggc attcctgccatcaaaccggc actgagcttc agccagagga ttgtcaacgg 120 ggagaatgca gtgttgggctcctggccctg gcaggtgtcc ctgcaggaca gcagcggctt 180 ccacttctgc ggtggttctctcatcagcca gtcctgggtg gtcactgctg cccactgcaa 240 tgtcagccct ggccgccattttgttgtcct gggcgagtat gaccgatcat caaacgcaga 300 gcccttgcag gttctgtccgtctctcgggc cattacacac cctagctgga actctaccac 360 catgaacaat gacgtgacgctgctgaagct cgcctcgcca gcccagtaca caacacgcat 420 ctcgccagtt tgcctggcatcctcaaacga ggctctgact gaaggcctca cgtgtgtcac 480 caccggctgg ggtcgcctcagtggcgtggg caatgtgaca ccagcacatc tgcagcaggt 540 ggctttgccc ctggtcactgtgaatcagtg ccggcagtac tggggctcaa gtatcactga 600 ctccatgatc tgtgcaggtggcgcaggtgc ctcctcgtgc cagggtgact ccggaggccc 660 tcttgtctgc cagaagggaaacacatgggt gcttattggt attgtctcct ggggcaccaa 720 aaactgcaat gtgcgcgcacctgctgtgta tactcgagtt agcaagttca gcacctggat 780 caaccaggtc atagcctacaactgagctca ccacaggccc tccccagctc aacccattaa 840 agacccaggc cctgtcccatcatgcattca tgtctgtctt cctggctcag gagaaagaag 900 aggctgttga gggtccgactccctacttgg acttctggca cagaaggggc tgagtgactc 960 cttgagtagc agtggctcttcctagagtag ccatgccgag gccggggccc ccacccctcc 1020 tccagggcaa ccccttggtcctacagcaag aagccagaac tgttggaatg aatggcagcc 1080 ctccctggag aggcagcctgtttactgaat acagaggata cgtttacaaa ctgaatacgc 1140 ataataaata actgcacattctccatccaa aaaaaaaaaa aaaa 1184 211 2437 DNA Homo sapiens 211 ctgcaatggcggctctagac tccctgtcgc tcttcactag cctcggcctg agcgagcaga 60 aggcccgcgagacgctcaag aactcggctc tgagcgcgca gctgcgcgag gccgctactc 120 aggctcagcagaccctgggt tccaccattg acaaagctac cgggatcctg ttatatggct 180 tggcctcccgactcagggat acccggcgtc tctccttcct tgtaagctac atagccagta 240 agaagatccacactgagccc cagctaagcg ctgcccttga gtatgtgcgg agtcacccct 300 tggaccccatcgacactgtg gacttcgagc gggaatgtgg cgtgggtgtc attgtgaccc 360 cagagcagattgaggaggct gtggaggctg ctattaacag gcaccggccc cagctcctgg 420 tggaacgttaccatttcaac atggggctgc tgatgggaga ggctcgggct gtgctgaagt 480 gggcagatggcaaaatgatc aagaatgaag tggacatgca ggtcctccac cttctgggcc 540 ccaagttggaggctgatctg gagaagaagt tcaaggtggc aaaagctcgg ctagaagaaa 600 cagaccggaggacggcaaag gatgtggtgg agaatggcga gactgctgac cagaccctgt 660 ctctgatggagcagctccgg ggggaggccc ttaagttcca caagcctggt gagaactaca 720 agaccccaggctatgtggtc actccacaca ccatgaatct actaaagcag cacctggaga 780 ttactggtgggcaggtacgt acccggttcc cgccagaacc caatggaatc ctgcatattg 840 gacatgccaaagccatcaat ttcaactttg gctatgccaa ggccaacaat ggcatctgtt 900 ttctgcgttttgatgacacc aaccctgaga aggaggaagc aaagttcttc acggccatct 960 gtgacatggtagcctggcta ggctacacac cttacaaagt cacatatgcg tctgactatt 1020 ttgaccagctatatgcgtgg gctgtggagc tcatccgcag gggtctggct tatgtgtgcc 1080 accagcgaggagaggagctc aaaggccata atactctgcc ttcaccctgg agagaccgtc 1140 ccatggaggagtcactgctg ctctttgagg caatgcgcaa gggcaagttt tcagagggcg 1200 aggccacactacggatgaag ctggtgatgg aggatggcaa gatggaccct gtagcctatc 1260 gagtcaagtatacaccacac caccgcacag gggacaaatg gtgcatctat cccacctacg 1320 actacacacactgcctctgt gactccatcg agcacatcac tcactcactc tgcaccaagg 1380 aattccaggcccgacgctct tcctacttct ggctttgcaa tgcactggac gtctattgcc 1440 ctgtgcagtgggagtatggc cgcctcaacc tgcactatgc tgttgtctct aagaggaaga 1500 tcctccagcttgtagcaact ggtgctgtgc gggactggga tgacccacgg ctctttacac 1560 tcacggccctgcgacggcgg ggcttcccac ctgaggccat caacaacttc tgtgcccggg 1620 tgggagtgactgtggcacaa accacaatgg agccacatct tctagaagcc tgtgtgcgtg 1680 atgtgctgaatgacacagcc ccacgagcca tggctgtgct ggagtcacta cgggtcatca 1740 tcaccaactttcctgctgcc aagtccttgg acatccaggt gcccaacttc ccagctgatg 1800 agaccaaaggcttccatcag gttccctttg cacccattgt cttcattgag aggactgact 1860 tcaaggaggagccagagcca ggatttaagc gcctggcttg gggccagcct gtgggcctga 1920 ggcatacaggctacgtcatt gagctgcagc atgttgtcaa gggccccagt ggttgtgtag 1980 agagtctggaggtgacctgc agacgggcag atgctggaga gaagccaaag gcctttattc 2040 actgggtgtcacagcctttg atgtgtgagg ttcgcctcta tgagcgacta ttccagcaca 2100 agaaccctgaagatcctact gaggtgcctg gtggattttt aagtgacctg aacctggcat 2160 cactacacgtggtggatgca gcattagtgg actgctctgt ggccctggca aaacccttcg 2220 acaagttccagtttgagcgt cttggatatt tctccgtgga tccagacagc catcagggaa 2280 agcttgtctttaaccgaact gtcacactga aggaagaccc aggaaaggtg tgagctggaa 2340 gcactgaacctacctcatcc tcctggaggg tgtggctacc ctcgccaccc caaattccat 2400 gtcaataaagaacagctaaa ttctcctaga aaaaaaa 2437 212 1830 DNA Homo sapiens 212tccgggtcag ctgactcccg actctgtgga gtctagctgc cagggtcgcg gcagctgcgg 60ggagagatga ctggggagcg acccagcacg gcgctcccgg acagacgctg ggggccgcgg 120attctgggct tctggggagg ctgtagggtt tgggtgtttg ccgcgatctt cctgctgctg 180tctctggcag cctcctggtc caaggctgag aacgacttcg gtctggtgca gccgctggtg 240accatggagc aactgctgtg ggtgagcggg agacagatcg gctcagtgga caccttccgc 300atcccgctca tcacagccac tccgcggggc actcttctcg cctttgctga ggcgaggaaa 360atgtcctcat ccgatgaggg ggccaagttc atcgccctgc ggaggtccat ggaccagggc 420agcacatggt ctcctacagc gttcattgtc aatgatgggg atgtccccga tgggctgaac 480cttggggcag tagtgagcga tgttgagaca ggagtagtat ttcttttcta ctccctttgt 540gctcacaagg ccggctgcca ggtggcctct accatgttgg tatggagcaa ggatgatggt 600gtttcctgga gcacaccccg gaatctctcc ctggatattg gcactgaagt gtttgcccct 660ggaccgggct ctggtattca gaaacagcgg gagccacgga agggccgcct catcgtgtgt 720ggccatggga cgctggagcg ggacggagtc ttctgtctcc tcagcgatga tcatggtgcc 780tcctggcgct acggaagtgg ggtcagcggc atcccctacg gtcagcccaa gcaggaaaat 840gatttcaatc ctgatgaatg ccagccctat gagctcccag atggctcagt cgtcatcaat 900gcccgaaacc agaacaacta ccactgccac tgccgaattg tcctccgcag ctatgatgcc 960tgtgatacac taaggccccg tgatgtgacc ttcgaccctg agctcgtgga ccctgtggta 1020gctgcaggag ctgtagtcac cagctccggc attgtcttct tctccaaccc agcacatcca 1080gagttccgag tgaacctgac cctgcgatgg agcttcagca atggtacctc atggcggaaa 1140gagacagtcc agctatggcc aggccccagt ggctattcat ccctggcaac cctggagggc 1200agcatggatg gagaggagca ggccccccag ctctacgtcc tgtatgagaa aggccggaac 1260cactacacag agagcatctc cgtggccaaa atcagtgtct atgggacact ctgagctgtg 1320ccactgccac aggggtattc tgccttcagg actctgcctt caggaacacg ggtctgtaga 1380gggtctgctg gagacgcctg aaagacagtt ccatcttcct ttagactcca gccttggcaa 1440aatcaccttc cctttaccag ggaaatcact tcctttagga ctgaaagcta ggcgtcctct 1500cccacaaaaa agtcctgccc tcatctgaga atactgtctt tccatatggc taagtgtggc 1560cccaccaccc tctctgccct cccgggacat tgattggtcc tgtcttgggc aggtctagtg 1620agctgtagaa ttgaatcaat gtgaactcag ggaactgggg aaggctgagc ctcctctttg 1680gtgttgcggt aagataaccg acagggctgg tgaaagtccc cagatggcag gatatttggt 1740ttcagagtaa ggactaggtg caccaccatg actgactatc aatcaaaatg tttgtaactt 1800aaaattttta atgaaggata atgaatattt 1830 213 1504 DNA Homo sapiens 213gggcctgcac gttgactgtg ggaaactcgg aaacaagctc acatcttcct gtgggaaacc 60ttctagcaac aggatgactc tgcagtggac tgcagttgcc accttcctct atgcggaggt 120ctttgttgtg ttgcttctct gcattccctt catttctcct aaaagatggc agaagatttt 180caagtcccgg ctggtggagt tgttagtgtc ctatggcaac accttctttg tggttctcat 240tgtcatcctt gtgctgttgg tcatcgatgc cgtgcgcgaa attcggaagt atgatgatgt 300gacggaaaag gtgaacctcc agaacaatcc cggggccatg gagcacttcc acatgaagct 360tttccgtgcc cagaggaatc tctacattgc tggcttttcc ttgctgctgt ccttcctgct 420tagacgcctg gtgactctca tttcgcagca ggccacgctg ctggcctcca atgaagcctt 480taaaaagcag gcggagagtg ctagtgaggc agccaagaag tacatggagg agaatgacca 540gctcaagaag ggagctgctg ttgacggagg caagttggat gtcgggaatg ctgaggtgaa 600gttggaggaa gagaacagga gcctgaaggc tgacctgcag aagctaaagg acgagctggc 660cagcactaag caaaaactag agaaagctga aaacgaggtt ctggccatgc ggaagcagtc 720tgagggcctc accaaggagt acgaccgctt gctggaggag cacgcaaagc tgcaggctgc 780agtagatggt cccatggaca agaaggaaga gtaagggcct ccttcctccc ctgcctgcag 840ctggcttcca cctggcacgt gcctgctgct tcctgagagc ccggcctctc cctccagtac 900ttctgtttgt gcccttctgc ttcccccatt cccttccaca gctcatagct cgtcatctcg 960gcccttgtcc acactctcca agcacattac aggggacctg attgctacac gttcagaatg 1020cgtttgctgt catcctgctt gcctgccagg cctgcacagc cttggcttca cgcctgagcg 1080tggagagcac gagttagttg tagtccggct tgcggtgggg ctgacttcct gttggtttga 1140gccccttttt gttttgccct ctgggtgttt tctttggtcc cgcaggaggg tgggtggagc 1200aggtggactg gagtttctct tgagggcaat aaaagttgta tgatgtttgt atgtgttttg 1260tatttctctg gagtgcaatg gtgcaatctc agctcactgc aacctctgcc tcccaggttc 1320aaaccattct cttgcctcag cctcctgagc agctgggatt acaggcgctg gccacacacc 1380cagctgattg ttgtattttt agtagagctg ggtttcacca tgttggccag gctggtctcg 1440aactcctgac ctcaggcaat ccacccacct cagcctccca acatgctgca attacagatg 1500tgag 1504 214 2370 DNA Homo sapiens 214 cacgagggag cgctaacgtc tttctgtctccccgcggtgg tgatgacggt gaaaactgag 60 gctgctaagg gcaccctcac ttactccaggatgaggggca tggtggcaat tctcatcgct 120 ttcatgaagc agaggaggat gggtctgaacgactttattc agaagattgc caataactcc 180 tatgcatgca aacaccctga agttcagtccatcttgaaga tctcccaacc tcaggagcct 240 gagcttatga atgccaaccc ttctcctccaccaagtcctt ctcagcaaat caaccttggc 300 ccgtcgtcca atcctcatgc taaaccatctgactttcact tcttgaaagt gatcggaaag 360 ggcagttttg gaaaggttct tctagcaagacacaaggcag aagaagtgtt ctatgcagtc 420 aaagttttac agaagaaagc aatcctgaaaaagaaagagg agaagcatat tatgtcggag 480 cggaatgttc tgttgaagaa tgtgaagcaccctttcctgg tgggccttca cttctctttc 540 cagactgctg acaaattgta ctttgtcctagactacatta atggtggaga gttgttctac 600 catctccaga gggaacgctg cttcctggaaccacgggctc gtttctatgc tgctgaaata 660 gccagtgcct tgggctacct gcattcactgaacatcgttt atagagactt aaaaccagag 720 aatattttgc tagattcaca gggacacattgtccttactg atttcggact ctgcaaggag 780 aacattgaac acaacagcac aacatccaccttctgtggca cgccggagta tctcgcacct 840 gaggtgcttc ataagcagcc ttatgacaggactgtggact ggtggtgcct gggagctgtc 900 ttgtatgaga tgctgtatgg cctgccgcctttttatagcc gaaacacagc tgaaatgtac 960 gacaacattc tgaacaagcc tctccagctgaaaccaaata ttacaaattc cgcaagacac 1020 ctcctggagg gcctcctgca gaaggacaggacaaagcggc tcggggccaa ggatgacttc 1080 atggagatta agagtcatgt cttcttctccttaattaact gggatgatct cattaataag 1140 aagattactc ccccttttaa cccaaatgtgagtgggccca acgagctacg gcactttgac 1200 cccgagttta ccgaagagcc tgtccccaactccattggca agtcccctga cagcgtcctc 1260 gtcacagcca gcgtcaagga agctgccgaggctttcctag gcttttccta tgcgcctccc 1320 acggactctt tcctctgaac cctgttagggcttggtttta aaggatttta tgtgtgtttc 1380 cgaatgtttt agttagcctt ttggtggagccgccagctga caggacatct tacaagagaa 1440 tttgcacatc tctggaagct tagcaatcttattgcacact gttcgctgga attttttgaa 1500 gagcacattc tcctcagtga gctcatgaggttttcatttt tattcttcct tccaacgtgg 1560 tgctatctct gaaacgagcg ttagagtgccgccttagacg gaggcaggag tttcgttaga 1620 aagcggacct gttctaaaaa aggtctcctgcagatctgtc tgggctgtga tgacgaatat 1680 tatgaaatgt gccttttctg aagagattgtgttagctcca aagcttttcc tatcgcagtg 1740 tttcagttct ttattttccc ttgtggatatgctgtgtgaa ccgtcgtgtg agtgtggtat 1800 gcctgatcac agatggattt tgttataagcatcaatgtga cacttgcagg acactacaac 1860 gtgggacatt gtttgtttct tccatatttggaagataaat ttatgtgtag acttttttgt 1920 aagatacggt taataactaa aatttattgaaatggtcttg caatgactcg tattcagatg 1980 cctaaagaaa gcattgctgc tacaaatatttctattttta gaaagggttt ttatggacca 2040 atgccccagt tgtcagtcag agccgttggtgtttttcatt gtttaaaatg tcacctgtaa 2100 aatgggcatt atttatgttt ttttttttgcattcctgata attgtatgta ttgtataaag 2160 aacgtctgta cattgggtta taacactagtatatttaaac ttacaggctt atttgtaatg 2220 taaaccacca ttttaatgta ctgtaattaacatggttata atacgtacaa tccttccctc 2280 atcccatcac acaacttttt ttgtgtgtgataaactgatt ttggtttgca ataaaacctt 2340 gaaaaataaa aaaaaaaaaa aaaaaaaaaa2370 215 991 DNA Homo sapiens 215 gggatcagtc ttcccgcgtc cgccgattcctcctccttgg tcgccgcgtc cttggctggc 60 gtcagaaaaa tggctacaaa cttcctagcacatgagaaga tctggttcga caagttcaaa 120 tatgacgacg cagaaaggag attctacgagcagatgaacg ggcctgtgcg aggtgcctcc 180 cgccaggaga acggcgccac ggtgatcctccgtgacattg cgagagccag agagaacatc 240 cagaaatccc tggctggaag ctcaggccccggggcctcca gcggcaccag cggagaccac 300 ggtgagctcg tcgtccggat tgccagtctggaagtggaga accagagtct gcgtggcgtg 360 gtacaggagc tgcagcaggc catctccaagctggaggccc ggctgaacgt gctggagaag 420 agctcgcctg gccaccgggc cacggccccacagacccagc acgtatctcc catgcgccaa 480 gtggagcccc cagccaagaa gccagccacaccagcagagg atgacgagga tgatgacatt 540 gacctgtttg gcagtgacaa tgaggaggaggacaaggagg cggcacagct gcgggaggag 600 cggctacggc agtacgcgga gaagaaggccaagaagcctg cactggtggc caagtcctcc 660 atcctgctgg atgtcaagcc ttgggatgatgagacggaca tggcccagct ggaggcctgt 720 gtgcgctcta tccagctgga cgggctggtctggggggctt ccaagctggt gcccgtgggc 780 tacggtatcc ggaagctaca gattcagtgtgtggtggagg acgacaaggt ggggacagac 840 ttgctggagg aggagatcac caagtttgaggagcacgtgc agagtgtcga tatcgcagct 900 ttcaacaaga tctgaagcct gagtgtgtgtacgtgcgcgc gtgcgtgagg gccctgccac 960 gattaaagac tgagaccggc aaaaaaaaaa a991 216 6381 DNA Homo sapiens 216 aaaaataact catattgtct ctgaggttcttttccagtga agtgtttagt attgccgcta 60 tttggagtac aaagttggag cttttaaagaacctgggagt tcaaaagtat aaggagaaat 120 aaatgaaaag cagaagtatt ttgaggcaataagtatagac tcaaatctat attatgaccc 180 acttgtagca ccacttggaa ttctaccaataagagattta tttgggcaaa ctataatggt 240 tgttggaaat tgcaaatctt agtgtgaattattttagtcc agttggtttc tttctttctc 300 ttacctgaaa tgaactatac tgaggcaataggagctttgt atagtaattt aggagtgtaa 360 aacaacttag ggaaaaggat tattaagcaggatgattggg atgacatcat gtgaaattta 420 ggaattggag gcattgggaa ttgagagggtgctaacaaag gaaaacagct tattttagaa 480 tttgtctgga ggatgtagaa ttgaagaagttttggtattt cttctgcagc ggccccagtg 540 cccttgacca ggaacatctc ttggagtcagtagttttcat gaggctgacc taggaacttg 600 gccaacatat gcaacattgt tctatttaaaatattccttg aattaaattc gatagtatca 660 atttaaaaca taaagttttc actcaactcctttagaagtt agattttagc ttgtacttgt 720 ctttacctct tctgctgatt atcagttgacaacactgaga ttactttcat tttcctgtaa 780 gtcattatga atttttctgg tcaaccatgagttatccagt ggaagccaat aagtaggaag 840 tactgtaaaa gaattacaat aaaataagagaaaccacttg gagagcaaga gggcttgtgg 900 acttggggga gcggttgtga gaaatgtctcagaacttaat ttacaaataa cattggtaga 960 ttgacatgtt gtctttccta taaagtaactttacctctgt cttaatagta aactactatg 1020 aaagtgaatt cgtgttcctc ttgatttgtgaactgatgaa aattacaaaa tgtggagttt 1080 tttccccaga taaagtaaat ggtggaatattcaggtttat ttgataccta gaaaatacct 1140 gaaattttcc gtggtaatag gcacattttgaaactgtttt ttttttctct gacaattgaa 1200 tatattttat atatagttga ttttgattattgaagactaa ggaaaatctt aagtttgaat 1260 gttagaaaat gaattttgca aatttgaagtaattttattc tttatgtttt gggattgtag 1320 ttatgttaga tattcctcag ttggggtaattgtcttgcat cattatctct tatcataatc 1380 tgtttttctt cacacagtgt tatagttttgccgctggact cttccctccc ttcccccacc 1440 ccatcaggat gatatgagac ttgaaagaagacgatgcata caggaggaga gacttcagca 1500 tgcaaacctt catctgttcg gcttgcaccgtcattttcat tccatgctgc tggccttcag 1560 atggctggac agatgcccca ttcacatcagtacagtgacc gtcgccagcc aaacataagt 1620 gaccaacagg tttctgcctt atcatattctgaccagattc agcaacctct aactaaccag 1680 aggcggatgc cccaaacctt ccgtgacccagcaactgctc ccctgagaaa actttctgtt 1740 gacttgatca aaacatacaa gcatattaatgaggtttact atgcaaaaaa gaagcgaaga 1800 caccaacagg gccagggaga cgattctagtcataagaagg aacggaaggt ttacaatgat 1860 ggttatgatg atgataacta tgattatattgtaaaaaacg gagaaaagtg gatggatcgt 1920 tacgaaattg actccttgat aggcaaaggttcctttggac aggttgtaaa ggcatatgat 1980 cgtgtggagc aagaatgggt tgccattaaaataataaaga acaagaaggc ttttctgaat 2040 caagcacaga tagaagtgcg acttcttgagctcatgaaca aacatgacac tgaaatgaaa 2100 tactacatag tgcatttgaa acgccactttatgtttcgaa accatctctg tttagttttt 2160 gaaatgctgt cctacaacct ctatgacttgctgagaaaca ccaatttccg aggggtctct 2220 ttgaacctaa cacgaaagtt tgcgcaacagatgtgcactg cactgctttt ccttgcgact 2280 ccagaactta gtatcattca ctgtgatctaaaacctgaaa atatccttct ttgtaacccc 2340 aaacgcagtg caatcaagat agttgactttggcagttctt gtcagttggg gcagaggata 2400 taccagtata ttcagagtcg cttttatcggtctccagagg tgctactggg aatgccttat 2460 gaccttgcca ttgatatgtg gtccctcgggtgtattttgg ttgaaatgca cactggagaa 2520 cctctgttca gtggtgccaa tgaggtagatcagatgaata aaatagtgga agttctgggt 2580 attccacctg ctcatattct tgaccaagcaccaaaagcaa gaaagttctt tgagaagttg 2640 ccagatggca cttggaactt aaagaagaccaaagatggaa aacgggagta caaaccacca 2700 ggaacccgta aacttcataa cattcttggagtggaaacag gaggacctgg tgggcgacgt 2760 gctggggagt caggtcatac ggtcgctgactacttgaagt tcaaagacct cattttaagg 2820 atgcttgatt atgaccccaa aactcgaattcaaccttatt atgctctgca gcacagtttc 2880 ttcaagaaaa cagctgatga aggtacaaatacaagtaata gtgtatctac aagccccgcc 2940 atggagcagt ctcagtcttc gggcaccacctccagtacat cgtcaagctc aggtggctca 3000 tcggggacaa gcaacagtgg gagagcccggtcggatccga cgcaccagca tcggcacagt 3060 ggtgggcact tcacagctgc cgtgcaggccatggactgcg agacacacag tccccaggtg 3120 cgtcagcaat ttcctgctcc tcttggttggtcaggcactg aagctcctac acaggtcact 3180 gttgaaactc atcctgttca agaaacaacctttcatgtag cccctcaaca gaatgcattg 3240 catcatcacc atggtaacag ttcccatcaccatcaccacc accaccacca tcaccaccac 3300 catggacaac aagccttggg taaccggaccaggccaaggg tctacaattc tccaacgaat 3360 agctcctcta cccaagattc tatggaggttggccacagtc accactccat gacatccctg 3420 tcttcctcaa cgacttcttc ctcgacatcttcctcctcta ctggtaacca aggcaatcag 3480 gcctaccaga atcgcccagt ggctgctaataccttggact ttggacagaa tggagctatg 3540 gacgttaatt tgaccgtcta ctccaatccccgccaagaga ctggcatagc tggacatcca 3600 acataccaat tttctgctaa tacaggtcctgcacattaca tgactgaagg acatctgaca 3660 atgaggcaag gggctgatag agaagagtcccccatgacag gagtttgtgt gcaacagagt 3720 cctgtagcta gctcgtgact acattgaaacttgagtttgt ttcttgtgtg tttttataga 3780 agtggtgttt tttttccaaa aacaaagtgcaaagctgctt gaatcaggag gagattaaca 3840 cactgaaccg ctacaagagg gcaaagctgatttttttttt taacttgaaa agattgcaaa 3900 gggacattga agtgtttaaa agagccatgtccaaacccat cttcatggat agctcagagg 3960 tatcctcttt ttgctccccc attttaacttgccacatccc agtcacagtg gggttttttt 4020 gtctttctat tcagcaaaag ttaatattcagatgttggtc ttggtcattt gccaactaat 4080 tttaaagtaa aaggcactgc acataatttgcataaagggc cccatgaggg tgtttttttt 4140 tttctttttg tcccccccat ccccctttttttttgttttg ttctgttttg ttttgggtgg 4200 gagggtggga aatttgggtt tttaagtcctctaaacacac ttgggcacgg aaatgcagta 4260 ctgtaaggaa gagggacctc cagcttccacaaacaccatc ttcagctgta tgaaagggac 4320 ggttgtggtg aagtttgtca ggcacagtaagcatgctgag tggcggggat cagaactctc 4380 ctatctgaac ctactgagga gcaaagcagcaattacatgg gatcctgtgg ctctcccgtt 4440 gcagaggcca caggaagata ggatggaacgtgactggtct cctaaccaag gtgcactgag 4500 aagcaatcaa cgggtcggtc gtggccagtcctggggaggt ctgagtggtg gtctttggga 4560 taacctttgg ccttatggat ttggactcgaaattagaaga gcctaccatt tcagatgcaa 4620 tcacttttgg acatgctttt gcagacagtccttaatgctg aaaacacaga gaatgggtaa 4680 ttcaagaggc ctttctttta aaatagacttttgtgaccca ctaattgtaa ggtattgcaa 4740 ggtcactttg cgtgtgtcat aaagttgacttccttattgg ttgaaggtca cagaagtagt 4800 ggtttgcttt gatggaaata gctacagctgtgtcccttcc tgctttttac tttttctttt 4860 gctttttctc ggcacgtggt atctccaccatttcttctgc acaaagatgt cttctgttca 4920 tcctgaacat ttttaaaaaa tgcagaattttatgtgactg cttttttgcc tcacaattat 4980 gctgtgaatt ttacaaaaat ttattttcttttttgataat ttattgtacc aaagctgttt 5040 ttatagcaca tagatgtctg taaccaataatgtagcagtt ctgcactttg acacaaggtg 5100 taactagacc atttttaaat gtcagttgaaaattatggct gtactattgc ttaaacaaaa 5160 ctggaactgt tgttgaatcc atagccaatacatttacagc aatctgtgta ctgaacatag 5220 tagattgaca tctaattcaa gattacaacatctgttacat tctaagtgtg ttcaggcttc 5280 tgaaggtaaa gggacactgg atccagaagctatggaacca gcagttgatt cttgtattcc 5340 tgattaacct acttgtaaac ttgaaagcaagaccttgatt gcaccaacag gtccagagta 5400 tgagtgcaag caaagcagaa ctctcatgcgtgacctgagc agacaggctg gtatttaaca 5460 ggtgcctcgt gttgagatta cgctgccttaatgtaacaca gtctggcagt tgctaaattt 5520 gtgttcccat tttaaattga ccaattttggggtgtgacac ttttgagcgg ttgaattggg 5580 agaatgaaga taagtaattt acctgtccaggatcaaaaga agcctagaaa agaagcagta 5640 atctacctct gccgataacc tgtttaagatgactcagcag aacaccgcgt ttcattctat 5700 tggtcaattc catgtggctg actaggtcaattttttttct gaacaaaagc aggtttttat 5760 atgtaaacag tgagaaaaga aaggctaaacactatgtaaa tgtgaatgga aacttggaaa 5820 tactcgtttt tataaactac aaaaactttttgttgtttat caggaaatcc atatttattt 5880 tgtaattaac tgtcaagcct gtggatgatttttttgaact tggtagttca taaaggttta 5940 cagtgaataa aaggatatca tcttgagtatagcaatatca aaaggaattc agtagttact 6000 gctgtttagg aatataaggt taagatatcatatgggtcag gtcatttttt ttttctgtgc 6060 tggttgccac atcttagcaa gcaccaaaaaactaaagcag tttttaaacc gatatttacg 6120 taaagaaaat cataaaatcc aatgcttctgcatactgtgt tatgttacag tccagttttg 6180 tgtgctttac tacacagttt ggttacaggacttctgtgca ttgtaaacat aaacagcatg 6240 gaaaaggtta aatacctgtg ttcagattgtaagatctagt ccggacttgc tgtgtatatt 6300 gtaacgttaa atgaaaaaag aacccccctttgtattatag tcatgcggtc ttatgtatga 6360 taaacagttg aataatttgt c 6381 2172514 DNA Homo sapiens 217 ctctcgtcgc ccccgctgtc ccggcggcgc caaccgaagcgccccgcctg atccgtgtcc 60 gacatgctgc gccgcgctct gctgtgcctg gccgtggccgccctggtgcg cgccgacgcc 120 cccgaggagg aggaccacgt cctggtgctg cggaaaagcaacttcgcgga ggcgctggcg 180 gcccacaagt acctgctggt ggagttctat gccccttggtgtggccactg caaggctctg 240 gcccctgagt atgccaaagc cgctgggaag ctgaaggcagaaggttccga gatcaggttg 300 gccaaggtgg acgccacgga ggagtctgac ctggcccagcagtacggcgt gcgcggctat 360 cccaccatca agttcttcag gaatggagac acggcttcccccaaggaata tacagctggc 420 agagaggctg atgacatcgt gaactggctg aagaagcgcacgggcccggc tgccaccacc 480 ctccgtgacg gcgcagctgc agagtccttg gtggagtccagcgaggtggc tgtcatcggc 540 ttcttcaagg acgtggagtc ggactctgcc aagcagtttttgcaggcagc agaggccatc 600 gatgacatac catttgggat cacttccaac agtgacgtgttctccaaata ccagctcgac 660 aaagatgggg ttgtcctctt taagaagttt gatgaaggccggaacaactt tgaaggggag 720 gtcaccaagg agaacctgct ggactttatc aaacacaaccagctgcccct tgtcatcgag 780 ttcaccgagc agacagcccc gaagattttt ggaggtgaaatcaagactca catcctgctg 840 ttcttgccca agagtgtgtc tgactatgac ggcaaactgagcaacttcaa aacagcagcc 900 gagagcttca agggcaagat cctgttcatc ttcatcgacagcgaccacac cgacaaccag 960 cgcatcctcg agttctttgg cctgaagaag gaagagtgcccggccgtgcg cctcatcacc 1020 ctggaggagg agatgaccaa gtacaagccc gaatcggaggagctgacggc agagaggatc 1080 acagagttct gccaccgctt cctggagggc aaaatcaagccccacctgat gagccaggag 1140 cgtgccggag actgggacaa gcagcctgtc aaggtgcctgttgggaagaa ctttgaagac 1200 gtggcttttg atgagaaaaa aaacgtcttt gtggagttctatgccccatg gtgtggtcac 1260 tgcaaacagt tggctcccat ttgggataaa ctgggagagacgtacaagga ccatgagaac 1320 atcgtcatcg ccaagatgga ctcgactgcc aacgaggtggaggccgtcaa agtgcacagc 1380 ttccccacac tcaagttctt tcctgccagt gccgacaggacggtcattga ttacaacggg 1440 gaacgcacgc tggatggttt taagaaattc ctggagagcggtggccagga tggggcaggg 1500 gatgatgacg atctcgagga cctggaagaa gcagaggagccagacatgga ggaagacgat 1560 gatcagaaag ctgtgaaaga tgaactgtaa tacgcaaagccagacccggg cgctgccgag 1620 acccctcggg gctgcacacc cagcagcagc gcacgcctccgaagcctgcg gcctcgcttg 1680 aaggaggcgt cgccggaaac ccagggaacc tctctgaagtgacacctcac ccctacacac 1740 cgtccgttca cccccgtctc ttccttctgc ttttcggtttttggaaaggg atccatctcc 1800 aggcagccca ccctggtggc ttgtttcctg aaaccatgatgtactttttc atacatgagt 1860 ctgtccagag tgcttgctac cgtgttcgga gtctcgctgcctccctcccg cgggaggttt 1920 ctcctctttt tgaaaattcc gtctgtggga tttttagacatttttcgaca tcagggtatt 1980 tgttccacct tggccaggcc tcctcggaga agcttgtcccccgtgtggga gggacggagc 2040 cggactggac atggtcactc agtaccgcct gcagtgtcgccatgactgat catggctctt 2100 gcatttttgg gtaaatggag acttccggat cctgtcagggtgtcccccat gcctggaaga 2160 ggagctggtg gctgccagcc ctggcggcgg cacagcctgggcctcccctt ccctcaagcc 2220 agggctcctc ctcctgtcgt gggctcattt gccaggctcaggccaggtct ggacagctgt 2280 gactctcctc aagccaggac taccgaccag ccggctatgggcacattacg tgaccactgg 2340 cctctctaca gcacggcctg tggcctgttc aaggcagaaccacgaccctt gactcccggg 2400 tggggaggtg gccaaggatg ctggagctga atcagacgctgacagttctt caggcatttc 2460 tatttcacaa tcgaattgaa cacattggcc aaataaagttgaaattttac cacc 2514 218 1082 DNA Homo sapiens 218 actcattctc cccagacgccaaggatggtg gtcatggcac cccgaaccct cttcctgcta 60 ctctcggggg ccctgaccctgaccgagacc tgggcgggct cccactccat gaggtatttc 120 agcgccgccg tgtcccggcccggccgcggg gagccccgct tcatcgccat gggctacgtg 180 gacgacacgc agttcgtgcggttcgacagc gactcggcgt gtccgaggat ggagccgcgg 240 gcgccgtggg tggagcaggaggggccagag tattgggaag aggagacacg gaacaccaag 300 gcccacgcac agactgacagaatgaacctg cagaccctgc gcggctacta caaccagagc 360 gaggccagtt ctcacaccctccagtggatg attggctgcg acctggggtc cgacggacgc 420 ctcatccgcg ggtatgaacggtatgcctac gatggcaagg attacctcgc cctgaacgag 480 gacctgcgct cctggaccgcagcggacact gcggctcaga tctccaagcg caagtgtgag 540 gcggccaatg tggctgaacaaaggagagcc tacctggagg gcacgtgcgt ggagtggctc 600 cacagatacc tggagaacgggaaggagatg ctgcagcgcg cggacccccc caagacacac 660 gtgacccacc accctgtctttgactatgag gccaccctga ggtgctgggc cctgggcttc 720 taccctgcgg agatcatactgacctggcag cgggatgggg aggaccagac ccaggacgtg 780 gagctcgtgg agaccaggcctgcaggggat ggaaccttcc agaagtgggc agctgtggtg 840 gtgccttctg gagaggagcagagatacacg tgccatgtgc agcatgaggg gctgccggag 900 cccctcatgc tgagatggaagcagtcttcc ctgcccacca tccccatcat gggtatcgtt 960 gctggcctgg ttgtccttgcagctgtagtc actggagctg cggtcgctgc tgtgctgtgg 1020 aggaagaaga gctcagattgaaaaggaggg agctactctc aggctgcaat gtgaaacagc 1080 tg 1082 219 3239 DNAHomo sapiens 219 gagctccatc ctgtgctcag ggggtagacg agggccccaa tgggctgaagctcatctcgg 60 aagtgattgg ggagcgcctc ggcatcccca tgagtgtgct gatgggggccaacattgcca 120 gcgaggtggc tgatgagaag ttctgtgaga caaccattgg tgagagccccctggcacctg 180 catacacagt gcatctagtt gcatcccctc cccaaactgc cccaaccccacttagccatc 240 tctttcccat aaggcagaga aaggaaaata caagcatcag aggtgaaggaggctgggaca 300 cccccaggga aggggcttca gggccttgct tagggaaaca cagtgatgagccctccctca 360 gagttggtgc agtggcacac ctgtggtccc agctacttaa gaggctgaggtgggaggatc 420 gcttaagccc aggagtttaa gtccagcctg ggcaacagag agagactcccatctctataa 480 aataaatatt ttttaaaaag agtccttccc tcaaagcctt gccccctcctcactttaggc 540 tgcaaggacc cggcccagga caactcctga aagagctgat gcagacaccaaacttccgta 600 tcacagtggt gcaagaggtg gacactgtag agatctgtgg agccttaaaggtgagagggg 660 cacagaggca gctatggggt gaggagaagg ccccaaagga ggtctggctgagctctgcaa 720 ggctgcaggt actccaggct ctcactattg agcagtggtt cccctttcctaccatgtccc 780 atgcatatag gaggagctgc agaagcaagg ccagggccat tcaggcggctgattattcat 840 catcagaccg tggaccccct tgctcctgtc ccattttagc cccgtgtgggactccccacc 900 ctctggctcc aggaggtggt cagggggaca aggagatgcc caggctaatgggagacaaaa 960 catccttgac acccagacag actaatggcc agaactatgg atcctggacagctgttgact 1020 tagggcttta caatggaatg gtcaatagat gggaagatca actagagagaagagtggttt 1080 tcagaaaatg tcctcgagga gggagtatgg ggcagggctt aagaaagggggtgcagcaag 1140 gggggaaacc aagaggcgga agtaggcttc taaaaggcca cacactatacctctcttctg 1200 cagtgggtgt cacggctgat gaaatgagta tgagggggct ccacatggggcctataggag 1260 ggggtctttt tctcacctat gacctccact ccttcaagaa tgtagtggccgtgggggctg 1320 gcttctgtga tggcctgggc tttggcgaca acaccaaggc ggcagtgatccggctgggtc 1380 tcatggagat gatagccttc gccaagctct tctgcagtgg ccctgtgtcctctgccacct 1440 tcttggagag ctgtggtgtt gctgacctga tcactacctg ctatggagggcggaaccgga 1500 aagtggctga ggcctttgcg cgtacaggaa aggtgggccc cgggagaagggagaacagag 1560 gggcggctct gtaggcatcc aggtagaggt gcttggcggg aggcatctctggagcacaaa 1620 cattaagact gttgtgcaca tccccatccc tcttttcctc ccaagaccccactcccatct 1680 gagctccagt ctctccaccc cctactgaca acccagctgc tcccttttccaagctttacc 1740 ctgaccagtc atgagtggat attctgaacc tgtttcatac tgtcttcttctaggagtctt 1800 tctcagacca gcacagctct gctctgatca gcccaatcac ccccgctgtcaaccccacac 1860 gcctttggca caatgaagtg ggtaaccttt atttcccttc tttttctctttagctcggct 1920 tattccaggg gtgtgtttcg tcgagatgca cacaagagtg aggttgctcatcggtttaaa 1980 gatttgggag aagaaaattt caaagccttg gtgttgattg cctttgctcagtatcttcag 2040 cagtgtccat ttgaagatca tgtaaaatta gtgaatgaag taactgaatttgcaaaaaca 2100 tgtgttgctg atgagtcagc tgaaaattgt gacaaatcac ttcataccctttttggagac 2160 aaattatgca cagttgcaac tcttcgtgaa acctatggtg aaatggctgactgctgtgca 2220 aaacaagaac ctgggagaaa tgaatgcttc ttgcaacaca aagatgacaacccaaacctc 2280 ccccgattgg tgagaccaga ggttgatgtg atgtgcactg cttttcatgacaatgaagag 2340 acatttttga aaaaatactt atatgaaatt gccagaagac atccttacttttatgccccg 2400 gaactccttt tctttgctaa aaggtataaa gctgctttta cagaatgttgccaagctgct 2460 gataaagctg cctgcctgtt gccaaagctc gatgaacttc gggatgaagggaaggcttcg 2520 tctgccaaac agagactcaa gtgtgccagt ctccaaaaat ttggagaaagagctttcaaa 2580 gcatgggcag tagctcgcct gagccagaga tttcccaaag ctgagtttgcagaagtttcc 2640 aagttagtga cagatcttac caaagtccac acggaatgct gccatggagatctgcttgaa 2700 tgtgctgatg acagggcgga ccttgccaag tatatctgtg aaaatcaagattcgatctcc 2760 agtaaactga aggaatgctg tgaaaaacct ctgttggaaa aatcccactgcattgccgaa 2820 gtggaaaatg atgagatgcc tgctgacttg ccttcattag ctgctgattttgttgaaagt 2880 aaggatgttt gcaaaaacta tgctgaggca aaggatgtct tcttgggcatgtttttgtat 2940 gaatatgcaa gaaggcatcc tgattactct gtcgtgctgc tgctgagacttgccaagaca 3000 tatgaaacca ctctagagaa gtgctgtgcc gctgcagatc ctcatgaatgctatgccaaa 3060 gtgttcgatg aatttaaacc tcttgtggaa gagcctcaga atttaatcaaacaaaattgt 3120 gagctttttg agcagcttgg agagtacaaa ttccagaatg cgctattagttcgttacacc 3180 aagaaagtac cccaagtgtc aactccaact cttgtagagg tctcaagaaacctaggaaa 3239 220 2428 DNA Homo sapiens 220 accttctgta tcagttaagtgtcaagatgg aaggaacagc agtctcaaga taatgcaaag 60 agtttattca tccagaggctgatgctcacc atggggcgcc tgcaactggt tgtgttgggc 120 ctcacctgct gctgggcagtggcgagtgcc gcgaagctgg gcgccgtgta cacagaaggt 180 gggttcgtgg aaggcgtcaataagaagctc ggcctcctgg gtgactctgt ggacatcttc 240 aagggcatcc ccttcgcagctcccaccaag gccctggaaa atcctcagcc acatcctggc 300 tggcaaggga ccctgaaggccaagaacttc aagaagagat gcctgcaggc caccatcacc 360 caggacagca cctacggggatgaagactgc ctgtacctca acatttgggt gccccagggc 420 aggaagcaag tctcccgggacctgcccgtt atgatctgga tctatggagg cgccttcctc 480 atggggtccg gccatggggccaacttcctc aacaactacc tgtatgacgg cgaggagatc 540 gccacacgcg gaaacgtcatcgtggtcacc ttcaactacc gtgtcggccc ccttgggttc 600 ctcagcactg gggacgccaatctgccaggt aactatggcc ttcgggatca gcacatggcc 660 attgcttggg tgaagaggaatatcgcggcc ttcggggggg accccaacaa catcacgctc 720 ttcggggagt ctgctggaggtgccagcgtc tctctgcaga ccctctcccc ctacaacaag 780 ggcctcatcc ggcgagccatcagccagagc ggcgtggccc tgagtccctg ggtcatccag 840 aaaaacccac tcttctgggccaaaaaggtg gctgagaagg tgggttgccc tgtgggtgat 900 gccgccagga tggcccagtgtctgaaggtt actgatcccc gagccctgac gctggcctat 960 aaggtgccgc tggcaggcctggagtacccc atgctgcact atgtgggctt cgtccctgtc 1020 attgatggag acttcatccccgctgacccg atcaacctgt acgccaacgc cgccgacatc 1080 gactatatag caggcaccaacaacatggac ggccacatct tcgccagcat cgacatgcct 1140 gccatcaaca agggcaacaagaaagtcacg gaggaggact tctacaagct ggtcagtgag 1200 ttcacaatca ccaaggggctcagaggcgcc aagacgacct ttgatgtcta caccgagtcc 1260 tgggcccagg acccatcccaggagaataag aagaagactg tggtggactt tgagaccgat 1320 gtcctcttcc tggtgcccaccgagattgcc ctagcccagc acagagccaa tgccaagagt 1380 gccaagacct acgcctacctgttttcccat ccctctcgga tgcccgtcta ccccaaatgg 1440 gtgggggccg accatgcagatgacattcag tacgttttcg ggaagccctt cgccaccccc 1500 acgggctacc ggccccaagacaggacagtc tctaaggcca tgatcgccta ctggaccaac 1560 tttgccaaaa caggggaccccaacatgggc gactcggctg tgcccacaca ctgggaaccc 1620 tacactacgg aaaacagcggctacctggag atcaccaaga agatgggcag cagctccatg 1680 aagcggagcc tgagaaccaacttcctgcgc tactggaccc tcacctatct ggcgctgccc 1740 acagtgaccg accaggaggccacccctgtg ccccccacag gggactccga ggccactccc 1800 gtgcccccca cgggtgactccgagaccgcc cccgtgccgc ccacgggtga ctccggggcc 1860 ccccccgtgc cgcccacgggtgactccggg gccccccccg tgccgcccac gggtgactcc 1920 ggggcccccc ccgtgccgcccacgggtgac tccggggccc cccccgtgcc gcccacgggt 1980 gactccgggg ccccccccgtgccgcccacg ggtgactccg gggccccccc cgtgccgccc 2040 acgggtgact ccggcgccccccccgtgccg cccacgggtg acgccgggcc cccccccgtg 2100 ccgcccacgg gtgactccggcgcccccccc gtgccgccca cgggtgactc cggggccccc 2160 cccgtgaccc ccacgggtgactccgagacc gcccccgtgc cgcccacggg tgactccggg 2220 gccccccctg tgccccccacgggtgactct gaggctgccc ctgtgccccc cacagatgac 2280 tccaaggaag ctcagatgcctgcagtcatt aggttttagc gtcccatgag ccttggtatc 2340 aagaggccac aagagtgggaccccaggggc tcccctccca tcttgagctc ttcctgaata 2400 aagcctcata cccctaaaaaaaaaaaaa 2428 221 3477 DNA Homo sapiens 221 accacctcca caacgattcccagatcgaag cggatttccg attgaatgat tctcataaac 60 acaaagataa acacaaagatcgagaacacc ggcacaaaga acacaagaag gagaaggacc 120 gggaaaagtc caagcatagcaacagtgaac ataaagattc tgaaaagaaa cacaaagaga 180 aggagaagac caaacacaaagatggaagct cagaaaagca taaagacaaa cataaagaca 240 gagacaagga aaaacgaaaagaggaaaagg ttcgagcctc tggggatgca aaaataaaga 300 aggagaagga aaatggcttctctagtccac cacaaattaa agatgaacct gaagatgatg 360 gctattttgt tcctcctaaagaggatataa agccattaaa gagacctcga gatgaggatg 420 atgctgatta taaacctaagaaaattaaaa cagaagatac caagaaggag aagaaaagaa 480 aactagaaga agaagaggatggtaaattga aaaaacccaa gaataaagat aaagataaaa 540 aagttcctga gccagataacaagaaaaaga agccgaagaa agaagaggaa cagaagtgga 600 aatggtggga agaagagcgctatcctgaag gcatcaagtg gaaattccta gaacataaag 660 gtccagtatt tgccccaccatatgagcctc ttccagagaa tgtcaagttt tattatgatg 720 gtaaagtcat gaagctgagccccaaagcag aggaagtagc tacgttcttt gcaaaaatgc 780 tcgaccatga atatactaccaaggaaatat ttaggaaaaa tttctttaaa gactggagaa 840 aggaaatgac taatgaagagaagaatatta tcaccaacct aagcaaatgt gattttaccc 900 agatgagcca gtatttcaaagcccagacgg aagctcggaa acagatgagc aaggaagaga 960 aactgaaaat caaagaggagaatgaaaaat tactgaaaga atatggattc tgtattatgg 1020 ataaccacaa agagaggattgctaacttca agatagagcc tcctggactt ttccgtggcc 1080 gcggcaacca ccccaagacgggcatgctga agagacgaat catgcccgag gatataatca 1140 tcaactgtag caaagatgccaaggttcctt ctcctcctcc aggacataag tggaaagaag 1200 tccggcatga taacaaggttacttggctgg tttcctggac agagaacatc caaggttcca 1260 ttaaatacat catgcttaaccctagttcac gaatcaaggg tgagaaggac tggcagaaat 1320 acgagactgc tcggcggctgaaaaaatgtg tggacaagat ccggaaccag tatcgagaag 1380 actggaagtc caaagagatgaaagtccggc agagagctgt agccctgtac ttcatcgaca 1440 agcttgctct gagagcaggcaatgaaaagg aggaaggaga aacagcggac actgtgggct 1500 gctgctcact tcgtgtggagcacatcaatc tacacccaga gttggatggt caggaatatg 1560 tggtagagtt tgacttcctcgggaaggact ccatcagata ctataacaag gtccctgttg 1620 agaaacgagt ttttaagaacctacaactat ttatggagaa caagcagccc gaggatgatc 1680 tttttgatag actcaatactggtattctga ataagcatct tcaggatctc atggagggct 1740 tgacagccaa ggtattccgtacatacaatg cctccatcac gctacagcag cagctaaaag 1800 aactgacagc cccggatgagaacatcccag cgaagatcct ttcttataac cgtgccaatc 1860 gagctgttgc aattctttgtaaccatcaga gggcaccacc aaaaaccttt gagaagtcta 1920 tgatgaactt gcaaactaagattgatgcca agaaggaaca gctagcagat gcccggagag 1980 acctgaaaag tgctaaggctgatgccaagg tcatgaagga tgcaaagacg aagaaggtag 2040 tagagtcaaa gaagaaggctgttcagagac tggaggaaca gttgatgaag ctggaagttc 2100 aagccacaga ccgagaggaaaataaacaga ttgccctggg aacctccaaa ctcagttatc 2160 tggaccctag gatcacagtggcttggtgca agaagtgggg tgtcccaatt gagaagattt 2220 acaacaaaac ccagcgggagaagtttgcct gggccattga catggctgat gaagactatg 2280 agttttagcc agtctcaagaggcagagttc tgtgaagagg aacagtgtgg tttgggaaag 2340 atggataaac tgagcctcacttgccctcgt gcctggggga gagaggcagc aagtcttaac 2400 aaaccaacat ctttgcgaaaagataaacct ggagatatta taagggagag ctgagccagt 2460 tgtcctatgg acaacttatttaaaaatatt tcagatatca aaattctagc tgtatgattt 2520 gttttgaatt ttgtttttattttcaagagg gcaagtggat gggaatttgt cagcgttcta 2580 ccaggcaaat tcactgtttcactgaaatgt ttggattctc ttagctactg tatgcaaagt 2640 ccgattatat tggtgcgtttttacagttag ggttttgcaa taacttctat attttaatag 2700 aaataaattc ctaaactcccttccctctct cccatttcag gaatttaaaa ttaagtagaa 2760 caaaaaaccc agcgcacctgttagagtcgt cactctctat tgtcatgggg atcaattttc 2820 attaaacttg aagcagtcgtggctttggca gtgttttggt tcagacacct gttcacagaa 2880 aaagcatgat gggaaaatatttcctgactt gagtgttcct ttttaaatgt gaattttttt 2940 tttttttaat tattttaaaatatttaaacc tttttcttga tcttaaagat cgtgtagatt 3000 ggggttgggg agggatgaagggcgagtgaa tctaaggata atgaaataat cagtgactga 3060 aaccattttc ccatcatcctttgttctgag cattcgctgt accctttaag atatccatct 3120 ttttcttttt aaccctaatctttcacttga aagattttat tgtataaaaa gtttcacagg 3180 tcaataaact tagaggaaaatgagtatttg gtccaaaaaa aggaaaaata atcaagattt 3240 tagggctttt attttttcttttgtaattgt gtaaaaaatg gaaaaaaaca taaaaagcag 3300 aattttaatg tgaagacattttttgctata atcattagtt ttagaggcat tgttagttta 3360 gtgtgtgtgc agagtccatttcccacatct ttcctcaagt atcttctatt tttatcatga 3420 attccctttt aatcaactgtaggttattta aaataaattc ctacaactta atggaaa 3477 222 147 DNA Homo sapiens222 cattcattca ctcaggctta gagaaacctc caggagactg ctaccatggc agagaagccc 60aagctccact actccaatac acggggcaga atggagtcca tccggtggct cctggctgca 120gctggagtag aggtaggttc tgagtta 147 223 914 DNA Homo sapiens 223ttttacagaa ctcccacgga cacaccatga taaggacgct gctgctgtcc actttggtgg 60ctggagccct cagttgtggg gaccccactt acccacctta tgtgactagg gtggttggcg 120gtgaagaagc gaggcccaac agctggccct ggcaggtctc cctgcagtac agctccaatg 180gcaagtggta ccacacctgc ggagggtccc tgatagccaa cagctgggtc ctgacggctg 240cccactgcat cagctcctcc aggacctacc gcgtggggct gggccggcac aacctctacg 300ttgcggagtc cggctcgctg gcagtcagtg tctctaagat tgtggtgcac aaggactgga 360actccaacca aatctccaaa gggaacgaca ttgccctgct caaactggct aaccccgtct 420ccctcaccga caagatccag ctggcctgcc tccctcctgc cggcaccatt ctacccaaca 480actacccctg ctacgtcacg ggctggggaa ggctgcagac caacggggct gttcctgatg 540tcctgcagca gggccggttg ctggttgtgg actatgccac ctgctccagc tctgcctggt 600ggggcagcag cgtgaaaacc agtatgatct gtgctggggg tgatggcgtg atctccagct 660gcaacggaga ctctggcggg ccactgaact gtcaggcgtc tgacggccgg tggcaggtgc 720acggcatcgt cagcttcggg tctcgcctcg gctgcaacta ctaccacaag ccctccgtct 780tcacgcgggt ctccaattac atcgactgga tcaattcggt gattgcaaat aactaaccaa 840aagaagtccc tgggactgtt tcagacttgg aaaggtcaca gaaggaaaat aatataataa 900agtgacaact atgc 914 224 4199 DNA Homo sapiens 224 cgtgttgatg atggagtagcttcctttgtg cttaatctcc catctggagt gacggtgctg 60 gagtttaatg tcaaaactgatgctccagat cttccagaag aaaatcaggc cagggaaggt 120 taccgagcaa tagcatactcatctctcagc caaagttacc tttatattga ttggactgat 180 aaccataagg ctttgctagtgggagaacat ctgaatatta ttgttacccc caaaagccca 240 tatattgaca aaataactcactataattac ttgattttat ccaagggcaa aattatccac 300 tttggcacga gggagaaattttcagatgca tcttatcaaa gtataaacat tccagtaaca 360 cagaacatgg ttccttcatcccgacttctg gtctattata tcgtcacagg agaacagaca 420 gcagaattag tgtctgattcagtctggtta aatattgaag aaaaatgtgg caaccagctc 480 caggttcatc tgtctcctgatgcagatgca tattctccag gccaaactgt gtctcttaat 540 atggcaactg gaatggattcctgggtggca ttagcagcag tggacagtgc tgtgtatgga 600 gtccaaagag gagccaaaaagcccttggaa agagtatttc aattcttaga gaagagtgat 660 ctgggctgtg gggcaggtggtggcctcaac aatgccaatg tgttccacct agctggactt 720 accttcctca ctaatgcaaatgcagatgac tcccaagaaa atgatgaacc ttgtaaagaa 780 attctcaggc caagaagaacgctgcaaaag aagatagaag aaatagctgc taaatataaa 840 cattcagtag tgaagaaatgttgttacgat ggagcctgcg ttaataatga tgaaacctgt 900 gagcagcgag ctgcacggattagtttaggg ccaagatgca tcaaagcttt cactgaatgt 960 tgtgtcgtcg caagccagctccgtgctaat atctctcata aagacatgca attgggaagg 1020 ctacacatga agaccctgttaccagtaagc aagccagaaa ttcggagtta ttttccagaa 1080 agctggttgt gggaagttcatcttgttccc agaagaaaac agttgcagtt tgccctacct 1140 gattctctaa ccacctgggaaattcaaggc attggcattt caaacactgg tatatgtgtt 1200 gctgatactg tcaaggcaaaggtgttcaaa gatgtcttcc tggaaatgaa tataccatat 1260 tctgttgtac gaggagaacagatccaattg aaaggaactg tttacaacta taggacttct 1320 gggatgcagt tctgtgttaaaatgtctgct gtggagggaa tctgcacttc ggaaagccca 1380 gtcattgatc atcagggcacaaagtcctcc aaatgtgtgc gccagaaagt agagggctcc 1440 tccagtcact tggtgacattcactgtgctt cctctggaaa ttggccttca caacatcaat 1500 ttttcactgg agacttggtttggaaaagaa atcttagtaa aaacattacg agtggtgcca 1560 gaaggtgtca aaagggaaagctattctggt gttactttgg atcctagggg tatttatggt 1620 accattagca gacgaaaggagttcccatac aggataccct tagatttggt ccccaaaaca 1680 gaaatcaaaa ggattttgagtgtaaaagga ctgcttgtag gtgagatctt gtctgcagtt 1740 ctaagtcagg aaggcatcaatatcctaacc cacctcccca aagggagtgc agaggcggag 1800 ctgatgagcg ttgtcccagtattctatgtt tttcactacc tggaaacagg aaatcattgg 1860 aacatttttc attctgacccattaattgaa aagcagaaac tgaagaaaaa attaaaagaa 1920 gggatgttga gcattatgtcctacagaaat gctgactact cttacagtgt gtggaagggt 1980 ggaagtgcta gcacttggttaacagctttt gctttaagag tacttggaca agtaaataaa 2040 tacgtagagc agaaccaaaattcaatttgt aattctttat tgtggctagt tgagaattat 2100 caattagata atggatctttcaaggaaaat tcacagtatc aaccaataaa attacagggt 2160 accttgcctg ttgaagcccgagagaacagc ttatatctta cagcctttac tgtgattgga 2220 attagaaagg ctttcgatatatgccccctg gtgaaaatcg acacagctct aattaaagct 2280 gacaactttc tgcttgaaaatacactgcca gcccagagca cctttacatt ggccatttct 2340 gcgtatgctc tttccctgggagataaaact cacccacagt ttcgttcaat tgtttcagct 2400 ttgaagagag aagctttggttaaaggtaat ccacccattt atcgtttttg gaaagacaat 2460 cttcagcata aagacagctctgtacctaac actggtacgg cacgtatggt agaaacaact 2520 gcctatgctt tactcaccagtctgaacttg aaagatataa attatgttaa cccagtcatc 2580 aaatggctat cagaagagcagaggtatgga ggtggctttt attcaaccca ggacacaatc 2640 aatgccattg agggcctgacggaatattca ctcctggtta aacaactccg cttgagtatg 2700 gacatcgatg tttcttacaagcataaaggt gccttacata attataaaat gacagacaag 2760 aatttccttg ggaggccagtagaggtgctt ctcaatgatg acctcattgt cagtacagga 2820 tttggcagtg gcttggctacagtacatgta acaactgtag ttcacaaaac cagtacctct 2880 gaggaagttt gcagcttttatttgaaaatc gatactcagg atattgaagc atcccactac 2940 agaggctacg gaaactctgattacaaacgc atagtagcat gtgccagcta caagcccagc 3000 agggaagaat catcatctggatcctctcat gcggtgatgg acatctcctt gcctactgga 3060 atcagtgcaa atgaagaagacttaaaagcc cttgtggaag gggtggatca actattcact 3120 gattaccaaa tcaaagatggacatgttatt ctgcaactga attcgattcc ctccagtgat 3180 ttcctttgtg tacgattccggatatttgaa ctctttgaag ttgggtttct cagtcctgcc 3240 actttcacag tgtacgaataccacagacca gataaacagt gtaccatgtt ttatagcact 3300 tccaatatca aaattcagaaagtctgtgaa ggagccgcgt gcaagtgtgt agaagctgat 3360 tgtgggcaaa tgcaggaagaattggatctg acaatctctg cagagacaag aaaacaaaca 3420 gcatgtaaac cagagattgcatatgcttat aaagttagca tcacatccat cactgtagaa 3480 aatgtttttg tcaagtacaaggcaaccctt ctggatatct acaaaactgg ggaagctgtt 3540 gctgagaaag actctgagattaccttcatt aaaaaggtaa cctgtactaa cgctgagctg 3600 gtaaaaggaa gacagtacttaattatgggt aaagaagccc tccagataaa atacaatttc 3660 agtttcaggt acatctaccctttagattcc ttgacctgga ttgaatactg gcctagagac 3720 acaacatgtt catcgtgtcaagcattttta gctaatttag atgaatttgc cgaagatatc 3780 tttttaaatg gatgctaaaattcctgaagt tcagctgcat acagtttgca cttatggact 3840 cctgttgttg aagttcgtttttttgttttc ttcttttttt aaacattcat agctggtctt 3900 atttgtaaag ctcactttacttagaattag tggcacttgc ttttattaga gaatgatttc 3960 aaatgctgta actttctgaaataacatggc cttggagggc atgaagacag atactcctcc 4020 aaggttattg gacaccggaaacaataaatt ggaacacctc ctcaaaccta ccactcagga 4080 atgtttgctg gggccgaaagaacagtccat tgaaagggag tattacaaaa acatggcctt 4140 tgcttgaaag aaaataccaaggaacaggaa actgatcatt aaagcctgag tttgctttc 4199 225 2633 DNA Homosapiens 225 ggattctctc tccaacccaa gtgcctccag ctgacctctg gctcctgtcctctggctcca 60 cctgcaccgc cctgctcttc ctaaggggcc aggaagcccc cagaagctctaccatcgacg 120 tgggtggtgg cacccggctc accctgagag cagaggccgt gcagggggctcagttctgag 180 ccccagccgg cccaccatgg cacggcggtt ccaggaggag ctggccgccttcctcttcga 240 gtatgacacc ccccgcatgg tgctggtgcg taataagaag gtgggcgttatcttccgact 300 gatccagctg gtggtcctgg tctacgtcat cgggtgggtg tttctctatgagaagggcta 360 ccagacctcg agcggcctca tcagcagtgt ctctgtgaaa ctcaagggcctggccgtgac 420 ccagctccct ggcctcggcc cccaggtctg ggatgtggct gactacgtcttcccagccca 480 gggggacaac tccttcgtgg tcatgaccaa tttcatcgtg accccgaagcagactcaagg 540 ctactgcgca gagcacccag aagggggcat atgcaaggaa gacagtggctgtacccctgg 600 gaaggccaag aggaaggccc aaggcatccg cacgggcaag tgtgtggccttcaacgacac 660 tgtgaagacg tgtgagatct ttggctggtg ccccgtggag gtggatgacgacatcccgcg 720 ccctgccctt ctccgagagg ccgagaactt cactcttttc atcaagaacagcatcagctt 780 tccacgcttc aaggtcaaca ggcgcaacct ggtggaggag gtgaatgctgcccacatgaa 840 gacctgcctc tttcacaaga ccctgcaccc cctgtgccca gtcttccagcttggctacgt 900 ggtgcaagag tcaggccaga acttcagcac cctggctgag aagggtggagtggttggcat 960 caccatcgac tggcactgtg acctggactg gcacgtacgg cactgcagacccatctatga 1020 gttccatggg ctgtacgaag agaaaaatct ctccccaggc ttcaacttcaggtttgccag 1080 gcactttgtg gagaacggga ccaactaccg tcacctcttc aaggtgtttgggattcgctt 1140 tgacatcctg gtggacggca aggccgggaa gtttgacatc atccctacaatgaccaccat 1200 cggctctgga attggcatct ttggggtggc cacagttctc tgtgacctgctgctgcttca 1260 catcctgcct aagaggcact actacaagca gaagaagttc aaatacgctgaggacatggg 1320 gccaggggcg gctgagcgtg acctcgcagc taccagctcc accctgggcctgcaggagaa 1380 catgaggaca tcctgatgct cgggccccaa ctcctgactg ggtacagcgtgaggcttcag 1440 cctggagccc tggtgggtcc cagccagggc agaggggcct ccccaggaagtctcctaccc 1500 tctcagccgg gcagagagca gtttgccaga agctcagggt gcatagtaggagagacctgt 1560 gcaaatctga gctccggctc cgaccccaca caccctgagg gagccctaccctagcctcag 1620 ccgctcctgg tggggaatgg ctggggctgg gcaggaccct cccacacacctgcaccctag 1680 cttcgtgctt ctctctccgg actctcatta tccaacccgc tgcctccatttctctagatc 1740 tgtgctctcc gatgtggcag tcagtaacca taggtgacta aattaaactaaaataaaata 1800 gaatgaaaca caaaattcaa ttcctcggct gaactagcca catttcaactgctcagtaga 1860 tacgtgtggt tagtggctgc catactggac agctcggggc attttcactgtcaaagaaag 1920 ttctattaga cagccctgct tgagccctgt ttcttcctgg ccttcggtttccctggggaa 1980 cttatcgaca atgcaagctc ctgggcccac ccccagacct cctgaaccaaaagctccagg 2040 gctggccgta tgatctgtgt ggatggcaaa ctccccaggc cattctgggacctaagttta 2100 agaagtgccg tcctcgaact ttctgactct aagctcctga gcgggagtcagacttagccc 2160 tgagcctgca cttcctgttc aggtgcagac actgaacagg gtctcaaacaccttcagcat 2220 gtgtgttgtg tgctcacgtg ccacacagtg tctcatgcac acaacccagtgtacacacca 2280 cctacgtgca cacagcatcc ttccacactg tgtatgtgaa cagcttgggccctgcaaaca 2340 caaccatcta cacacatcta cacccccaag cacacacaca tggtccgtgccatgtcacct 2400 ccatagggaa aggcttctct ccaagtgtgc caggccagga cagccctcccagccatgaat 2460 ccttactcag ctacctcggg ttggggtggg agccccagcc aaatcctgggctccctgcct 2520 gtggctcagc cccagctccc aaggcctgcc tggctctgtc tgaacagaaggtctggggga 2580 agcgaggggt ggagtacaat aaagggaatg aggacgaaaa aaaaaaaaaaaaa 2633 226 3454 DNA Homo sapiens 226 cgcgcggcca ggccctctta gccctctgccgtttgggggg cacgggtgaa cctgccgccc 60 cactcccacc ccgccccgcc ccgcccgtacagacaaatcg gaagggacga gcctgccctt 120 tgaaagggtt ttttttcttg ctcctgcggagggcgcccca gccatggccc tcaggagctc 180 cctagacccc gcagggactg ccctccatcccggccgccgg ggcccgccct ctgcatcccg 240 cgggcagcct gtgtgaagcg gcctcccgcagcccccggcc cctcccccat ggaggaggag 300 gagggggcgg tggccaagga gtggggcacgacccccgcgg ggcccgtctg gaccgcggtg 360 ttcgactacg aggcggcggg cgacgaggagctgaccctgc ggaggggcga tcgcgtccag 420 gtgctttccc aagactgtgc ggtgtccggcgacgagggct ggtggaccgg gcagctcccc 480 agcggccgcg tgggcgtctt ccccagcaactacgtggccc ccggcgcccc cgctgcaccc 540 gcgggcctcc agctgcccca ggagatccccttccacgagc tgcagctaga ggagatcatc 600 ggtgtggggg gctttggcaa ggtctatcgggccctgtggc gtggcgagga ggtggcagtc 660 aaggccgccc ggctggaccc tgagaaggacccggcagtga cagcggagca ggtgtgccag 720 gaagcccggc tctttggagc cctgcagcaccccaacataa ttgcccttag gggcgcctgc 780 ctcaaccccc cacacctctg cctagtgatggagtatgccc ggggtggtgc actgagcagg 840 gtgctggcag gtcgccgggt gccacctcacgtgctggtca actgggctgt gcaggtggcc 900 cggggcatga actacctaca caatgatgcccctgtgccca tcatccaccg ggacctcaag 960 tccatcaaca tcctgatcct ggaggccatcgagaaccaca acctcgcaga cacggtgctc 1020 aagatcacgg acttcggcct cgcccgcgagtggcacaaga ccaccaagat gagcgctgcg 1080 gggacctacg cctggatggc gccggaggttatccgtctct ccctcttctc caaaagcagt 1140 gatgtctgga gcttcggggt gctgctgtgggagctgctga cgggggaggt cccctaccgt 1200 gagatcgacg ccttggccgt ggcgtatggcgtggctatga ataagctgac gctgcccatt 1260 ccctccacgt gccccgagcc ctttgcccgcctcctggagg aatgctggga cccagacccc 1320 cacgggcggc cagatttcgg tagcatcttgaagcggcttg aagtcatcga acagtcagcc 1380 ctgttccaga tgccactgga gtccttccactcgctgcagg aagactggaa gctggagatt 1440 cagcacatgt ttgatgacct tcggaccaaggagaaggagc ttcggagccg tgaggaggag 1500 ctgctgcggg cggcacagga gcagcgcttccaggaggagc agctgcggcg gcgggagcag 1560 gagctggcag aacgtgagat ggacatcgtggaacgggagc tgcacctgct catgtgccag 1620 ctgagccagg agaagccccg ggtccgcaagcgcaagggca acttcaagcg cagccgcctg 1680 ctcaagctgc gggaaggcgg cagccacatcagcctgccct ctggctttga gcataagatc 1740 acagtccagg cctctccaac tctggataagcggaaaggat ccgatggggc cagcccccct 1800 gcaagcccca gcatcatccc ccggctgagggccattcgcc tgactcccgt ggactgtggt 1860 ggcagcagca gtggcagcag cagtggaggaagtgggacat ggagccgcgg tgggccccca 1920 aagaaggaag aactggtcgg gggcaagaagaagggacgaa cgtgggggcc cagctccacc 1980 ctgcagaagg agcgggtggg aggagaggagaggctgaagg ggctggggga aggaagcaaa 2040 cagtggtcat caagtgcccc caacctgggcaagtccccca aacacacacc catcgcccct 2100 ggcttcgcca gcctcaatga gatggaggagttcgcggagg cagaggatgg aggcagcagc 2160 gtgccccctt ccccctactc gaccccgtcctacctctcag tgccactgcc tgccgagccc 2220 tccccggggg cgcgggcgcc gtgggagccgacgccgtccg cgccccccgc tcggtgggga 2280 cacggcgccc ggcggcgctg cgacctggcgctgctaggct gcgccacgct gctgggggct 2340 gtgggcctgg gcgccgacgt ggccgaggcgcgcgcggccg acggtgagga gcagcggcgc 2400 tggctcgacg gcctcttctt tccccgcgccggccgcttcc cgcggggcct cagcccaccc 2460 gcgcgtcccc acggccgccg cgaagacgtgggccccggcc tgggcctggc gccctcggcc 2520 accctcgtgt cgctgtcgtc cgtgtccgactgcaactcca cgcgttcact gctgcgctct 2580 gacagtgacg aggccgcacc ggccgcgccctccccaccac cctccccgcc cgcgcccaca 2640 cccacgccct cgcccagcac caaccccctggtggacctgg agctggagag cttcaagaag 2700 gaccccggcc agtcgctcac gcccacccacgtcacggctg tatgcgctgt gagccgcggg 2760 caccggcgga cgccatcgga tggggcgctggggcagcggg ggccgcccga gcccgcgggc 2820 catggccctg gccctcgtga ccttctggacttcccccgcc tgcccgaccc ccaggctctg 2880 ttcccagccc gccgccggcc ccctgagttcccaggccgcc ccaccaccct gacctttgcc 2940 ccgagacctc ggccggctgc cagtcgcccccgcttggacc cctggaaact ggtctccttc 3000 ggccggacac tcaccatctc gcctcccagcaggccagaca ctccggagag ccctgggccc 3060 cccagcgtgc agcccacact gctggacatggacatggagg ggcagaacca agacagcaca 3120 gtgcccctgt gcggggccca cggctcccactaaggcctgc ccaccaccgc ccgcctgggc 3180 agccatgaat gtagcgcccc aggccctgccccagcccgcc atgccacaag gtgggggagg 3240 ccctgggcag gatgttcact ctatttattggggaaggagg gagggggggg acacttaact 3300 tattcctttg taccccaggg ggtggagccctgtgcccacc ctgcactggg gggagggtgg 3360 gcagggatac tcagggacag ggcatcatgggggatttggc acaaaatgga acaataaagg 3420 taaccccttg cccccccccc caaaaaaaaaaaaa 3454 227 141 DNA Homo sapiens 227 atgcagcctg acatcccgtt tccccaggccagaggtaggt ttgaagtgag gtctgtgtca 60 ctgtggtatt atgattacgt ttgggggtaagactacggta tggacgtctg gggccaagga 120 accacggtca ccgtctcctc a 141 2281922 DNA Homo sapiens 228 gagacctggg cgttggtgaa ggcgagggga aagccagaatactggggtgg cggacgccaa 60 ggggcgggtg tagcaggcaa cctcagggaa gctgggaaggcctagcaggg tgagagaacc 120 cgcacacggg gggcacagcg cctccctcgc gagccggtgcgaaaggggcc gcctgcggtg 180 tgcgcccagc tgcgctcaag ggaccttgca cttggcccatctcctgcgca cagcccaggc 240 cgggaccgcg ggcggtgcgg actcagcggg ctgggtgcaagggcggggcg gggcgtctgc 300 gcccggcccc gtctcctgac tataaaagca gccgctggctgttgggctcc actccgcctt 360 ccacgtgcac ccactgcctc ttcccttctc gcttgggaactctagtctcg cctcgggttg 420 caatggaccc caactgctcc tgtgccgctg gtaagggacgcccgggttct gtgccttgga 480 atgccaaatt cccagacacc atagagagtg tccctgggtttgaggaggtc gtattttgct 540 atcagaggta aggggactcc tttattggtc cagtgctttcctgttggcca agctcctgag 600 ggcattttcc tcctccctgt tcctctatgt cagagttgagggtcctgagg ctcaaggctg 660 tcctgctcat gtcagagttg agggtcctga ggctcaaggctgtcctgcct cacgtcacct 720 agttggtcac agggctgctg gctgagcccc aattctctaacctgactctg agctaccgga 780 ttggatagga gacattggat aggagggaca ttgcctcttccaagttcagg acagaaagtc 840 gaagtcttcc taggccgtga tctgcaggga ctttcctttggagtagaaat aggagggtgc 900 ttggttttcc cagcatgaat ggagaggaca tggggcttctcttcctcgtc tctgagtggg 960 aaaggagctc tgacggctgg ctctggcaca gagaagggggaagtggacac tcattgaccc 1020 actgctgtac cttctgcatc tcactcaccg ttcactggctttttctcttc tagcaggtgt 1080 ctcctgcacc tgcgccagct cctgcaagtg caaagagtgcaaatgcacct cctgcaagaa 1140 gagtgagtgc ggggccatct ccaggaatct ggggctgtggctaaggttgg gagggaaccc 1200 aaggctgtcc ctgagtgcct gcttctgggg aaccggccttcctttgtccc tgtaggttgt 1260 cacgcctgtc tagtcttctg cactttccaa ggcttatgtgaggtggggca gctttctcaa 1320 aggaagaccc attccaatgt ccaccagttg tctcctgacaaaaaccatgc catcatgaac 1380 taagggtcct ctggggctgg agggatggag acaggcctctgttggggcag ggagttctat 1440 gatcgagtct gctctgacct ctcaatctcc tttcctccccaaggctgctg ctcctgctgc 1500 cctgtgggct gtgccaagtg tgcccaaggc tgcatctgcaaaggggcatc ggagaagtgc 1560 agctgctgcg cctgatgtcg ggacagccct gctcccaagtacaaatagag tgacccgtaa 1620 aatctaggat tttttgtttt ttgctacaat cttgacccctttgctacatt cccttttttc 1680 tgtgaaatat gtgaataata attaaacact tagacttgattcccgttctg gttcctgttg 1740 tgtttttgga atgagggact ggggtgggag attgaactgggagttcacac tgggctctgg 1800 acggaaatgt gagtgctaaa caagctgagc gccttcaggcagccccgtta cttctctgac 1860 ctccttcctc tgtaaaaggc acctgcaccg tgccggatgatatggggatg gggacatacg 1920 cg 1922 229 929 DNA Homo sapiens 229ggttgtccag ccacaaaggt gacagcattt aacaaagctt agagaaacct ccaggagact 60gctaccatgg cagagaagcc caagctccac tactccaata tacggggcag aatggagtcc 120atccggtggc tcctggctgc agctggagta gagtttgaag agaaatttat aaaatctgca 180gaagatttgg acaagttaag aaatgatgga tatttgatgt tccagcaagt gccaatggtt 240gagattgatg ggatgaagct ggtgcagacc agagccattc tcaactacat tgccagcaaa 300tacaacctct atgggaaaga cataaaggag aaagccctga ttgatatgta tatagaaggt 360atagcagatt tgggtgaaat gatccttctt ctgcccttta ctcaacctga ggaacaagat 420gccaagcttg ccttgatcca agagaaaaca aaaaatcgct acttccctgc ctttgaaaaa 480gtcttaaaga gccacggaca agactacctt gttggcaaca agctgagccg ggctgacatt 540cacctggtgg aacttctcta ctacgtggaa gagcttgact ctagccttat ttccagcttc 600cctctgctga aggccctgaa aaccagaatc agtaacctgc ccacagtgaa gaagtttcta 660cagcctggca gcccaaggaa gcctcccatg gatgagaaat ctttagaaga atcaaggaag 720attttcaggt tttaataaac cagccataga ggtcaagaac atgcaagacc agtattctaa 780agttttgcaa caattaagtg ctttacctaa gtgttgattg tgcctgttgt gaagctaatg 840aactctttca aattatatgc taattaaata atacaactcc tattcaccca cttagttaaa 900attgatttct tctcattagg atctgatgt 929 230 314 DNA Homo sapiensmisc_feature n=a,t,g or c 230 aatacaacat atggagttac agctgatcaaaaaagagatc acaggaattg gacccagtac 60 cacaacagaa acagaaacaa tcgccaaatatgaaataatg gatggtgcac aagtaanagg 120 tgaatcaatt ccaataaggc tatttttagcaggatatgac ccaactccaa caatgagaga 180 tgtgaacaaa aaattttcag taaggtactttttgaattta gtgcttgttg atgaggaaga 240 ccggagtact tcaaacagca ggagataattttatggagaa aagctcctga aaaacttgag 300 gaaacagaga acaa 314 231 408 DNAHomo sapiens 231 aaaaagccaa atgcttaaac tgatcaatga ctgtagcttt ttagactgttggtcaaagaa 60 cattctactt cacagtaata gctctatcag ccacagatct catggtggctgttgcatgat 120 aatgatagga taaacaaaat accactgtct tcaagaaaca ttatcttaggtttgtttgtt 180 tggtttgagt ttgatttggc ttttatattt tttaaaatcc cttttgctaccccatctggt 240 tttataaact gagtttctta gcattcgtta aaattaaggg gtttgtttggaataatatat 300 attttttatg cttttgtctt tcttacctga ttgatattac attcacctttgattgttttt 360 taaaagttta tttttacaga atatatttag tacctttctt aaggagta 408232 431 DNA Homo sapiens 232 ggtgtacatc tattcctcag ggagtgtgga ggcacagaaactgttattcg ggcattctac 60 ggagggagat attcttgagc ttgttgatgg tcactttgataccaagattg gacacaaagt 120 agagagtgaa agttaccgca agattgcaga cagcattgggtgctcaacca acaacatttt 180 gtttctgaca gatgttactc gagaggccag tcctgctgaggaagcagatg tgcacgtagc 240 tgtggtggtg agaccaggca acgcaggatt aacagatgatgagaagactt actacagcct 300 catcacatcc ttcagtgaac tatacctccc ttcctcaacctagagaaggg ttgttaaggc 360 agaccgccct gttccccaga gttgtccctc tagtgtctaggttattctaa tggtaaaggt 420 aacttactta a 431 233 542 DNA Homo sapiens 233tttttggaaa gtaactacac catattcatt gtttaaaact ctttactgat gtacatgttt 60taataaaaca aataaccaaa aaaaatacac aaatccatag ttatttaaaa acttaggatt 120tttaaaaaac atgtctataa aaatacaacg tttaaggcag tttggaaatg catttgtaca 180tttctacaac gtccataaat tctcttgaaa ataagaatgt taacttcaat tctataaaat 240acactgtaca ttttaagact gttctaaata tagcacactt caatggactg tgggttttga 300ttcctgatga caaatggatt ctatacattt caggggggaa aggtgtaata tggatgtgag 360tttaaaactt ttaatttctt tttaaaaata aattatttct gaagcataca atttataaaa 420attctatata caaagtacag caactggtaa caaaccccag ttttaataca ttttatatac 480gatgtaccag ggtttagcaa cctgatagga gcagaggcaa tatacattct ccgcatattt 540 aa542 234 3088 DNA Homo sapiens 234 gctggaaggg tttctttggc cctgagtgaagagagaccca gagggaacac tgaggtgcct 60 gcccaaccac tctgtcccgg tttccttcagcaggaccagg tgagagaagc catgctggtc 120 gttcagatgc ctttctcctt tcccatggcccacttcatcc tctttgtctt tacggtttcc 180 actatatttc acgttcagca gcggctagcgaagattcaag ccatgtggga gttaccggtg 240 cagataccag tgctagcctc aacatcaaaggcactgggac ccagccagct cagggggatg 300 tggacgatca atgcaatagg ccgcctggggaaccagatgg gcgagtacgc cacactgtac 360 gccctggcca agatgaacgg gcggcccgccttcatcccgg cccagatgca cagcaccctg 420 gcccccatct tcagaatcac cctgccggtgctgcacagcg ccacggccag caggatcccc 480 tggcagaact accacctgaa cgactggatggaggaggaat accgccactt cccgggggag 540 tacgtccgct tcaccggcta cccctgctcctggaccttct accaccacct ccgccaggag 600 atcctccagg agttcaccct gcacgaccacgtgcgggagg aggcccagaa gttcctgcgg 660 ggcctgcagg tgaacgggag ccggccgggcacctttgtag gggtccatgt tcgccgaggg 720 gactatgtcc atgtcatgcc aaaagtgtggaagggggtgg tggccgaccg gcgataccta 780 cagcaggccc tggactggtt ccgagctcgctacagctccc tcatcttcgt ggtcaccagt 840 aatggcatgg cctggtgtcg ggagaacattgacacctccc acggtgatgt ggtgtttgct 900 ggcgatggca ttgagggctc acctgccaaagattttgctc tactcacaca gtgtaaccac 960 accatcatga ccattgggac gttcgggatctgggccgcat acctcacggg cggagacacc 1020 atctacctgg ccaattacac cctccccgactcccctttcc tcaaaatctt taagccagag 1080 gcagccttcc tgccggagtg gacagggattgccgcagacc tgtccccctt actcaagcac 1140 taatgctggc ccattctttg agaccttttctccttctctg cctccctcaa gatgagtgcc 1200 cgggcatgag aagcacatgg ttccatgagcaggacccatc tctcttctgt gaagatgcgt 1260 tgggctgcaa gtaacagaaa tctcagtgaacagtggcctg gcgtggtggc tcatgcctgt 1320 aatgctcgca ctttgggagg ccagggtgggtggatcactt gaggtcagga gttcaagact 1380 agcctggcca acatggtgaa accccatctcgactaaaaat acaaaaatta gccaggcgtg 1440 gtggtgcaca cttgtaatcc cagctactcgggaggctgag gcaagagaat cacttgaacc 1500 caggaggcgg aggttgcagt gagccaagatggtgccgctg cactccagcc tgggtgacac 1560 agcaagactc catctcaaaa aaaaaaaaagaaaaagaaat gaacgggttc aaagaccata 1620 atcatgcata tcacataaga ccagaagtggcccaggtcca gggtcagtta atttagcagc 1680 tccacaaagt catcagtcac ctgagctccatccatcttca catgctgtgc taccatttct 1740 tagctgtatc atcccatggt cccaaaagggctgctacaca tccagccatc acatgcagat 1800 aattcctttc aaaaacagca gaaagaggctcgttcttgtc ttggtccctt ttgaagaatg 1860 aatgaaacct tcctaagcct tccagcaatttccccccaac tccgatgggt aggaattgtc 1920 acatacccat gtgacccgat aggaggcaaaagaaatgaga cttctgggat tagtttagcc 1980 tcagattctg cagctgagaa gttgatcagccacctctgaa ggacatgcag cttgcagaaa 2040 attagggtgg tgttaccaag gtgaaaaggggaaatggctt tagagtagac aacagagatg 2100 ccctgagggg ttgtgtaggt tgttcactgcaggaagtccc ctggttaaga aggcaagtgg 2160 ggtttaaaca gacccacagt ctactcatcaaaccaggtgt ccttggcatt gtgtccaccc 2220 agagagctca ctgttttctt ttctttttcttttctttttt tttttttgag atggagtctt 2280 gctgcatccc ccaggctgga gtgcagtggcatgatcttgg ctcactgcag cctccgcctc 2340 ccaggttcag gcgattctcc tgcctcagcctcccgagtgg ctgggattgc aggtgcgtgc 2400 caccacgccc agctaatttt gtacgtttagtggaaatgga gtttcaccat gttggtcagg 2460 ctggtctcaa actcctgacc tcatgatccgccttcctcgg cctcccaagg tgctgggatt 2520 acaggtgtta gccactgcgc ccggccctagagctcactgt tttctagtta gtccatctgg 2580 aagtggagcc tttttccagt ttgcacaaatgtgccatatt ggcttgtagc tggcatgcat 2640 ccaagtccat aggtcctgcc tcttcaatcctggctttcta gggcctggga tgatcattgc 2700 tagaactgag agaccagcct ggctgagtgaacttcagggc gttccgttca ttctttcagt 2760 aaatggttgc agcacatgtt ttacatgtcaggcagtgaaa ccccccacag cagccttccc 2820 tctcagagga tacatttgta accattacacagtcatcaaa ggaataattt tttttaatca 2880 ccagtgtgca tacagtcatg gagctgggtattcccagcta ccagggaggc tgaggtggga 2940 ggattgcttg atgccaggag ttagggaatatagtgcaccg tgattggact tgcgaatagc 3000 cactgcactg cggcctggac gacgtagtgataccctgact cttataaata aataaatgaa 3060 taaacacaat tatgactttg cggatggg3088 235 314 DNA Homo sapiens 235 tttttttttt tttttttttt cttccctttcccagcccatt gtttttattt tttaatcagt 60 tttaggaaag tataacttat atacaataaaaggcaccctt cttaaatgca cagtttgatg 120 agttttgaca aatgtttaag cagtacagccatcaccataa ttaagatata caatatttcc 180 atcacatcaa gaagttgtct catctccttcatggtcagtc tgctgttcct ggcaatcact 240 gatcgatttt ctgttcctat agatttgccttttctggaga gtccatataa gtgcaggaat 300 tttcgtttgt agcc 314 236 233 DNAHomo sapiens 236 gaaagttcag ttcagtttat tacagtgtca agtagattta caactattgcacttatcatt 60 ctggtgacag aaggccaaaa ctgaagattg agattttcct ctaataaagataggttttca 120 gaatcttcaa tataagatgt taaaattata aaggcaaaga tatatacctcatgttccatt 180 ccatatcctt cctgctgttg tacagtttgc tgcaaatgat aatttaatttggg 233 237 253 DNA Homo sapiens 237 tttttcagct agaaataagt tattttattttaaaacacat acagattaat aaatattact 60 ggaaaactta atagcctttt tatttacatgaggcaataac aacatgctat gactacatct 120 ataaagcaaa atataagcag gtcttggccactgacacatg tgtctatgta tgctaattgg 180 aagctcccca atacatgtct atgacaaaacttttacacaa ccaatcaaca tttgacattt 240 tttacatctt ctt 253 238 263 DNA;Homo sapiens misc_feature n=a,t,g or c 238 ggttagtaca caaatagtttatgcagtaaa taactgtggt tacagttcat tgttgtcagc 60 aatacagcat tttccatcacaattataggt gaaacaaaac ctcatgaagt agtcatagca 120 cattcatgct agcgagagcatattacaaag caatgcacgt gcattatagg ggcagacaaa 180 actggggaag ggctatatttncactcacct ctggttaact ttgtgtattt tgtcattaag 240 acttacatta tgtttgggtcaaa 263 239 259 DNA Homo sapiens misc_feature n=a,t,g or c 239catgtttatt gttgttttat ttagtgttat aattggaaat gtggaaaaca caagagataa 60ccatagtcat aatatacaag gcttccttat aatgagtact ttttnctaca acctcataga 120attatggtaa gtgtattatt ttaaaaggng antttagtag gntaaaacac actgaatttt 180agtccaacta cagctatgta catatgcata cataatttat gagctatgta taattnatat 240gtatacaaac accacattt 259 240 325 DNA Homo sapiens misc_feature n=a,t,gor c 240 aagatatttt acttttttnc tttaatcagc acatttcttt tgataaatagtcatgagacg 60 tgttctgtga gtcactacaa ttctcacttg gcacttggaa cagtcgtgttatataggttt 120 accataactc tcagaacagg agtatattac aaacaagtgg agtagaacatagagaataca 180 taatttgttc taatattcct cttccttaga gccttcaaac ttaaaccaagttgaaaaaaa 240 aagtttccca aattgaaaac attgcctatg gattatctac agaagagaggaaaataagca 300 accattttga ttccacaaac caagc 325 241 445 DNA Homo sapiensmisc_feature n=a,t,g or c 241 ttttttttta atgtccaaca gataactaaaattcaaattt tatttttcca tatttatcag 60 acaatttttt tctgacaaga ctttactgaaagatgaagtg caaatgggaa ccctgtaaaa 120 atgtttataa gagttgtaca tgacatattttaagcgccgc taagtacaca ttgaatactt 180 tgtaagtata taggcatatc aacatgcaagtgtcatgtac caaatattac aatatgcatt 240 ttgttttttg aaaatgttaa tgacaagagtagattcaata actgtgtttc tctactttct 300 gtgcttatat ggttaatttg ttgggatcttctttataggc acagaattta ttttttatgc 360 tgtncattaa atataccctt ccaaaagttatggattatca tgtcatataa ataggcacat 420 tttttttttg gaggctactt acggg 445 242461 DNA Homo sapiens 242 tttttgcctt tatgcagaaa caggccttaa atcaactgtataacaaatct tcctctatca 60 ataagtttgg ctggtaaaga aagtttctgg gtaaggaacaaatagaatta tagccccact 120 tactttacca cataatcagc tttgctaata agaaaattcagagctaaaat agaagatcga 180 aacatttggc ttgcctaagt acttaccacg ttttaaagttgctctgtgct gcttatttta 240 ggtagggtga atgcaaaata taaactttaa aaaaaaaacattgttttatt tatttagtta 300 gttttttaga gacagagtct tactatgttg cccggctggactctaactcc tggggctcaa 360 gcaatcctcc cacatcagcc tccccagtag gctgggattccgggcacgtc cagcagcaaa 420 atatcttaat atacatgggg cattaaaatt cacacagggg t461 243 306 DNA Homo sapiens 243 tatggcataa tctctgtcct ttgtatcatctgtactttta tacctccttg ccttcttttt 60 ttttctgacc cttttgttgt tgttgttatttagcaattct taacaggatg gattagagga 120 cacagtggag attaaaactc caatagttaattgtcctgat gaaatgttgg cattgcattg 180 tctggattaa atgtatttat ctctggccttgttactcact gataaactaa tacagttgta 240 tgaaatggga tattctgtat gctttaaacaacctttaaat taaaaactag gtgcttttgg 300 attact 306 244 336 DNA Homo sapiensmisc_feature n=a,t,g or c 244 ctnnaaatat caaaagaagt ttattaaaatacatattttg ttatacataa aacttagaaa 60 tatttcaaga tttacataca tcaacttttgcaatcttcct gctggtaaaa atacaaaaca 120 gcagcataag aaccagttac tcatatactcaactatattc atgcatactt aacaaaatga 180 aaagttctcc taaaaactgg caagatacaaaatgtcaaat ctaaaatgat atatatactt 240 acgtttttag gcattcttac aggattacaaacccttacca acattaatct tgggcctact 300 ttaaagttga gtgataggca tggaactctggaaaag 336 245 384 DNA Homo sapiens misc_feature n=a,t,g or c 245atcattttaa aaagggcttt aatactgttt aagtagttca aataggcttc ctcactatta 60atttgcttca gtaaactctt cagcttaact cattatctta aatttcagaa ttaatgaggt 120tttactgtaa aagtagaaaa gcaaacactt caaatgataa gactccagta tcacccatac 180taaaanctta ggcaataaaa ctgcagtttg aaaagctact gtacaatgca gcaaggacta 240ggtgtcaata ctgctggaag cgtagccagg gtaaagganc aggaaatctg cacagtntta 300tccctgtggg ttcttagnct cattcggaan tacaggaact gcaatctcac aatggnaaca 360aacatactgg cttnttaggg gggg 384 246 330 DNA Homo sapiens 246 tgtggataaatatattagca aataaatata tttcttaaca tagtgcctga ttcaagcgtc 60 tgtctggttcagatataaat acccatgtgg gtacctaggt gctagtctcc ccactaactg 120 agggaaaaaggttcccaggt ggggtcctct gcccactttg ccaccacatt cacattccaa 180 atgggataatgcctgagggg ccaagagtgg tcaggctgcc ctggggtgaa tgtcaccctg 240 atgaggcccatcagctcttg tccactcagt gaggccagac ttgtgctcta atccactctc 300 ctgtgggtccctggcctgta tggcttatac 330 247 417 DNA Homo sapiens 247 aaattggcattctatatatt tgagaaacta atgtataaaa attcaagata attacaattg 60 gaaggggaccaataattcca ctttttaatc gaaaataatc tatatactcc caataaactc 120 acagtaaaataagcttcaaa aagccttaag acaccaaaag aggaaaaaaa gccagtaatt 180 agaacaaaatgtgtaatgtg gttaatagta tagatatgct tgcctttaga caattcttat 240 atactcaattcttacatgat tgaaagattc tgtaataatg ctctaccttt ttataaagaa 300 aaaagtaggtttccaaaaga aaattaaacg tttatgactg gagttagcgg tagtaaggaa 360 ttagatgtgagtggttgact gctctttgtg ccttcgacat tttgcagaaa attctgt 417 248 385 DNA Homosapiens 248 ctttttaaat tatatagtcc catggatttt caaatatttt atactagttatataataaca 60 ctattttaaa aactatatag aataaacagc actgaggaga gatgaagcaatagaaaggtc 120 aaagttcaaa cttgttaaaa tatgtttggc tttgtttccc taaggttggaattattaaac 180 tggtgtgact ttagaaggtt ttcgaggaat tggtgtgtgt tactgcagaatcactagctc 240 ttaatttgta atttgatggc taaaaacgga caagtcactt aaaggaatatatcgtattaa 300 aaagttactt tccttgacat ttggccacca gtcagccctg tctcccctagcctctgtctg 360 aaagtatgga aagacattta gcctg 385 249 345 DNA Homo sapiens249 tccatgaatt caaagccttt taatgatgtg aacacttact ccccatttct tttttacatt 60gttacaaaaa atttacatac agttttctga aagtggcatt ttgttggttg ttattatact 120gatgacacat attaacactt tgtattgaag aagtatcata aaaatcacag ggcattacag 180atttttgata agaagtagta atagcattgt cttttaacag ctggaggctc ccaggcatac 240tctttggtga gaaatgatta attttatatt ttcattttga tgagaatctt ttcttgtttt 300taccagttat aaaaacaaag ctttttcttt gttgtgatac tgtgg 345 250 399 DNA Homosapiens misc_feature n=a,t,g or c 250 ttttaattaa ccagtgtaaa aatagtgccttcaaaatgga atattctcac aaataaaagc 60 caagcaactt cttagtgaat ctgacagaaaaagtcattct cagtaacagc ttcctccaaa 120 aatttttccc attaatgcac atactttttggcttgtatta ctgaaatgtt gctttacctt 180 tccatttccc cttacttgta ggaggattcattctgatggg ctaatttgat gtttatttag 240 gttctggaaa aaagggntaa ttaggaaattaggggggggg tgcaggatcc ggtggttatt 300 tttaaaccta acccnggtaa agtcaagggaaatattatcc cncagggccc nccactncat 360 taggttgcct agggccaaat ggtaaatgcaggggggttt 399 251 304 DNA Homo sapiens misc_feature n=a,t,g or c 251tttttttttg gatcattata ttttcttgaa tattcattca agtttcaatt taatacttaa 60acattcattt tcgaataaaa atactatgtc ttgtactagg gatacaaaga cttggttatt 120cttgttggag taatgattct cctctatctg gggaggtcat cctctgcagt tggggactga 180aggactggga gatgggagat tgaaacttaa agagggtaaa ggtatgtctt gggantaaaa 240ctagttatca gtcaccaccc ngaccatcat gggcggctng gatttccagg aaccggtgat 300tggg 304 252 171 DNA Homo sapiens misc_feature n=a,t,g or c 252tttttttaag aaaggtagat aaatttattg ccacttgaaa actaaatata actcagaatg 60agtcagacaa aaaaaatcat tgacattaaa attattatta tttgaccngg tttgtctttt 120gaagaatttc tctcacaggc acttctgcaa caaatttgta taatttaata t 171 253 278 DNAHomo sapiens misc_feature n=a,t,g or c 253 tttttttttt tttttttacttgaactaata aagtttatta atgtcacaaa atacgagatt 60 aatatacaag atgaaataatacttttatat aacagtaatc gacatactaa aaattaagtc 120 aagaaaaaat ttaataataacattggaaaa accatttggg aacatatttt taaaagcaag 180 tacacatact ttacagtgaaanttatttaa aatgctggaa ggaaattttt aaaactgtat 240 aggggaagga tatatctaatattccagggt tatcaata 278 254 384 DNA Homo sapiens misc_feature n=a,t,g orc 254 tttcttttga aaaggaaaga tatatatatt taatatataa aagaaaatgc taaatctgac60 ataattatat tcttaaaaac attccattta tttacagatg tataaaaagg tgaattattg 120gtctattgag atcatgcttc ttatagtntt agggtgagag ctcactgtct tccacgttcc 180tcaactcctc tcactcaact tcacctttca taatcacaca tgtaatattc ataggatcag 240ttccccctag gggtaagggt taaagggtag ggagtttttg ggaggatttt aggatttctg 300tcaaggactg cagggattgt tctgaaggac taaggccctc ctcaaattat ccctggacaa 360cacctaggtt ctaggggggt cttg 384 255 382 DNA Homo sapiens misc_featuren=a,t,g or c 255 ataaagagcn aattncttta ttctgaagat aatggggaga cactgaaatatttgaatcaa 60 gaatgatgtg atgagattgg cagttcaaat accggtcaag tgaaaggcctgaaataaggc 120 agcggctgta ttagaaaagt ggacagattg cagaggtaaa atcattagaatagctgtttc 180 catgtgggga gggggatgag agaaagtcct tgagccgaca aggactcccaagtttctctg 240 tgggatgatg ggtatattga ttttttttgt catcattggg taaaggaaaacacaagaggg 300 ggggaaatat ttctggaacc ntacctagta gggggccctg ccncataggtagggtgtttc 360 cattaatngg ctgttttgaa cc 382 256 391 DNA Homo sapiensmisc_feature n=a,t,g or c 256 tttttttttt actgtttgga aaaatttttattcactggaa aaatgtttat aaagaaatat 60 taagtgaaat gttgagaaat atatagaactttacataaaa tatattagcc atgcaaatac 120 atgagtgtac gctttctgtg gatagacataaatattgcta gagaaaaaaa tagaaaagaa 180 tccatcaagg gcattaacta cacatttttctacgttacca gtatcttagg tgttctaggg 240 tgtaggttat taaaatttcc ttctctgtactttctaaaat tttaataata gggatgtgct 300 ttttaaaata atttttttaa cttggatatctcacctggtc ncctgaggtt ccccttttct 360 ccaacttaat ggggggctta accggcccnc t391 257 284 DNA Homo sapiens misc_feature n=a,t,g or c 257 ttttttttttggtagttaaa acagaaggtt tcaataaaat cgacagtctg ataacataat 60 acccaaaagtccaagtttcc attgaaaatc attcatcata ccaagaacca ggaaaatctc 120 atactgaatgaaaataggca gcaagcacac actggcaata aaatgagaga agcgctggga 180 ttgtctgacaaacattttaa agcaagcaag cctgatgaaa atgatttagc gagtaattat 240 gagcacacttgaaataaatg gacaagtagg aaagtcttag gcaa 284 258 398 DNA Homo sapiensmisc_feature n=a,t,g or c 258 tttttttttt gccccaagaa aacgttnacccagtgatctt gggctggggt tgtctttagg 60 aaaagttgag actataagag tcataaataagtccttgtgt ttccttaatt tatnttgtta 120 acacccctaa ttacaaccaa agtgatgatgtggagtcttc tgtcttcatt ttggccccag 180 cattcttaat ttcaaagctt tattctgtctgcctaagaga atcaaccaaa ggtgattctc 240 ctaaagagca gtgaaggaaa tgtcaggttagcaggaccca agttttgggt gtgaaatgtt 300 gccagcttcc tataatgtaa acggacttgttaacctaacc taattatgct cagtggactt 360 ctnttagatg gttttgaaaa atgaactgagctgacttt 398 259 364 DNA Homo sapiens misc_feature n=a,t,g or c 259atagtcaaag tngcagcagc tcatttattt agccaaaaat agatactttc tcgtacaatt 60tggttcacac atatgtacat ttctctgtat atatacacac acacaaaggc agacacgttt 120attctcactg aaactccacc ccccaaaatc aaccggacaa acaaacctca cagcgaatgg 180ngngtgccac agaagcgact tggggagggc tgaggaggac tggttttatt tctttttctt 240actttctttg tttagttttg cttttagggt atttatacac gggacatgct tacaagttgt 300aactatacag nggcgatttt ttttatacaa ttatttacaa cggtttaaaa aaggtttttt 360ttgt 364 260 430 DNA Homo sapiens misc_feature n=a,t,g or c 260tttttttttt cagncacagg tagttttatt gttatgtttc acctagntag gcaattttta 60aaaatagtgt gtagaaatga atagtttcaa actgagtaaa tatagtagta taccatgtca 120taaaacaatc aaatcaaaag caactgccaa gctaataata agtcaaagaa atagtaattc 180tggcttgtac agatatgtgc agtgttttca aagctcttaa cagttaacca ctaacatgta 240tctccaaagc ttaacttagn agttggaaga tgaatttcac agtaatgtaa ttttaaccac 300catttacatt cactttaata tattactang gatgtttact cctatgtnca caatgggtgc 360tttcccagtg ttccacantt tcacagtttc caatttgtac atatgtgatt gcactaacnt 420tggggacagt 430 261 417 DNA Homo sapiens misc_feature n=a,t,g or c 261tttttttttt tttttttttt ttttgagcca aagagaagaa atgatttatt aacatgggga 60caccaagaaa aacaaagtat gcttttattc cctttgtcaa gctcagtttt agggtttttn 120ctttttttta tagtgacaat ccatagatat agacattcct aaaagaaaaa taaataattc 180agtagatata tgtcactgtt acctgaatat ggaatgaatt tgatgttttt tattttgttg 240agacagggtc ttgctctgtc acccagactg gagtncagtg gcatgatcac acctcactgc 300agccttggcc tctcaggctc gtgatcctcc tgcctcaacc tcggcaagta ggcttgggga 360ctacagggcg tntgccacca gtccnggggt aattttttgt aggatataag ggtctca 417 262244 DNA Homo sapiens misc_feature n=a,t,g or c 262 gtggcacaca ataattttaatataacaatt atgattatta ctgataatgt acactaagtt 60 atattagaat tataggagtttcacataatt ttggaacata caccaataac atatttatac 120 aaatacagcc caaagaaaaccaaacaccat ttcacatttg acaatgcttc ctatataatt 180 ttnataccaa ataggccaanttatgtcatt ttagggnctt taggggaaac taagntctta 240 aagg 244 263 272 DNAHomo sapiens misc_feature n=a,t,g or c 263 taagatnant actcaacaacagcaaaattt attcttctca agtgcacatg aaacatatta 60 ccaatacaga ccatattctgggccatgaaa caagttttga tatgttttaa catattcaag 120 tcatataaag tacattcctttaccataatg taattaaatt agaagtcaat agcagaaaga 180 tctctggaaa atgtccaaatatgtggaagt taaataacac agttctaagt aacacaaaaa 240 tcataaactt tttggntaatanggcaaaac gg 272 264 479 DNA Homo sapiens misc_feature n=a,t,g or c 264gtatagagca gaaaatggat agtcagataa agaagcagac tttcacaata tcatatgtta 60attttgtaat gagatagttg tttagactag taaatagatc agggttaaag gctttgattg 120aatcagatta tgaaaggtgc caaacacaaa ggaccgtcca agtctaacac ttacagattc 180agctggtaaa gaaataatga actaatttta gattcagcca gattattact tatatacata 240gtgaagaana gagaagctaa aggtgtcagc cctatgagtc cttatcccaa accaaaaggn 300tggcactgaa acaaaagggg tcagatggct tcagcaagga gttgtgatac accctattgc 360tggccagtca attccagact ggcagctaan tggctataga gctgcagttc tgccctacgg 420gngcctaggg gttaagttgg gagtctcntg ttcccctggg ccnggggttt atatcngtt 479 265418 DNA Homo sapiens misc_feature n=a,t,g or c 265 ctntaattaa ccagatgatactctaangaa aattgganca tacatatggt ttcctataaa 60 tgatcctgtg caatttgaccttttgaactc ttagatttct tctttgctag ataggagttt 120 ggactagatg atcttgaaagttccttttaa atctatattt ctttagtgat atatcttgta 180 tctaatcttc agaatgttcactctcaaact aaagtcatcc cattacatct ccttggaaaa 240 tcaatgggaa atcccttattttagaagagg ttcaacaaac atgaagtgct atttgaggat 300 gttcctggaa aggttaaataacttgaaagg gttataattt cactattaac cngggcaaac 360 tcttccnggg ggtnctccttagggataggt aaaataccat ggaattaaaa ataaatct 418 266 396 DNA Homo sapiensmisc_feature n=a,t,g or c 266 ccatcagcca gtcgtcaggg nntccgggtcagctggttga caagcagcct agtacctccc 60 ctcctttccc atccctaaac cacactggcttcttttttcc aaaaacatta cagctcatct 120 ttaagggtga ttcatgatac tttctaaacagccacagtag ctgaaacatt ggactactgg 180 ggaaattcca gccttgaaca gactttggttttcattccag ttttactaat ttgttctcta 240 atcttacaag aaattaggac catgtgtgtgggcgcatgta gggctgtgag gtaattttat 300 ctttgccaag ctcatacttg ggcattatagtcagtggatt tctgtggtcc atggctgggc 360 tagcctgggg cttcagaggg gactgttcccctaaaa 396 267 223 DNA Homo sapiens misc_feature n=a,t,g or c 267catatatnna atantaaaaa tcctgggagg cattgcactg taatagtaag tctgcccatc 60caggntcatg catgtctttt ctttcattca agtcttattt tatatctttc agtaaatttt 120catatagatc ttgtgaatcg aattattttt acatttcaaa ttcaactaac aattattaat 180aganaatgaa aacattgatt tttttcaata tttattttgt gtc 223 268 472 DNA Homosapiens misc_feature n=a,t,g or c 268 caaatttaac ttgctattga gaaagtttaacaaattgttt aacctgaaag acaaatttcc 60 tggtaaacaa ccatttaaca tcccctgtgtctttgcctca aatccattac caacaaggca 120 gtcatccttt caaaatgcaa atctgattatatcacacttg actagtttaa aatttgtcaa 180 cccttcctat taattttatg ttgaggagcaaacttcttaa catgacccat ttatcatgta 240 tcatccaaac tgggacactc tgagagtgaaaagagagtga ttaattttta taccagtaaa 300 ccaggggcag cccctaggaa aagaggttaggtgtgggcta tcccacccac aaggccctac 360 ctcttcaaat tccttcacat tctccctcactgtttcccct ccaggntccc tccagcaggg 420 cnttttgtta ggggnaaaat taatttaggtggggacagtg ggttatggcc tt 472 269 304 DNA Homo sapiens misc_featuren=a,t,g or c 269 gaggtgtccc caacaatttt attataaata aaaacaagac tcccagtgggtggctgcagc 60 ccctgcctcg gtggctgtna gcacctnttg gaggggcctg cccttaccctggtctggagg 120 ccagaaccga ggaaagggct ncctgcccct ccaagtacac aggggagcctgaggtactga 180 gaattaaaaa ccagggaggg actcccaggc caggcggcgg ccccgggccctctgccccac 240 gaggctcatc ccttggagca cacaggaagt tgcccgtcca tnacaccacacttttttnca 300 gncg 304 270 203 DNA Homo sapiens 270 taaaaatatatactttttta ttgttaagaa acattttcat aaataagtac ttatttcatt 60 ccttactgaaatggcttttt ttttactgac ccattgaaac catgttggct atgttcaaca 120 taactagagatatctttggc gttttcctcc cttagcttca tatcttgtag aacatcttgt 180 acaaaaaagtagatttacag aaa 203 271 277 DNA Homo sapiens misc_feature n=a,t,g or c271 ttaagtatca aagttaagtt taataaagta agttccttcc attttgtaat gtataaaata 60ataccattta aacaggcaga aactagctaa tctgcattta tagagcatag ttttttgggt 120gggaaaaaag cattctttca tcatttcacc tttactagaa gaaacagact tatgatggtt 180cttactatta tttttcaact ttagaattat tcattcagta gaagctgtat ttcaagtacc 240caaccattct gtttttcact ttcaatgtaa tcttcaa 277 272 415 DNA Homo sapiensmisc_feature n=a,t,g or c 272 tagagacagg gtctcgctct gtctccaaagctggagtgca gctccatcat ggttcactgc 60 agcctccgnc tcccgggttt gagcgatcctcccatttcag tgtaaccacc attcttatct 120 ctatcaccat agattagctc tgcatgtctttgaacttcat ataaatggaa tcatgcatag 180 ataggctctt ttgtgtctgg attctctctgttaacactgt gtctgtgaga ctcactcatg 240 ctgtgtgtag tattatgctt catccttttttgttgttgca tagtattcca ctgtataaat 300 ataccacaat ttatttgtct gttttcccaattgctgtgca tttggggatt gttttggttt 360 ttcacctatt ttggaataag gctgcctagggaccaccctt ggtatagggc ctggg 415 273 386 DNA Homo sapiens misc_featuren=a,t,g or c 273 tttttttttt ttttgagacg gagnnngctt ctgtcgccca gggtgcagtgcagtggcacg 60 attcatggct cactgcagcc tcgacttcct gggcccaagt gatccttgcacctcagcctc 120 ccaagtagct gggactacag gtgcatgcca tcacgcccag ctaggtttttaatttttgca 180 gaggcggtgt ctccatatgt tgctcaggtt ggtntcaagc aatcctnttgccacagcctc 240 ccaaagtgct gggattacag gtntgagccc tgtacctagc caactttttctttaagaccc 300 tttctctttc attatttgat caaaaacaaa tctgactttc tctgaacttctgaacaggaa 360 ataaaatgga atctcctact acattg 386 274 177 DNA Homo sapiensmisc_feature n=a,t,g or c 274 ttttgatgan ggnngtaatc aatcttttattcacagctac aaactttaat caattatgga 60 taaaacacaa aagctttttg aaatgctgataaaggaaccc ataccngaga gaccaaataa 120 aatccgagtn ctgagctggc catggntttggcaggtcagc agcacatgga ggcacag 177 275 378 DNA Homo sapiens 275ttttttacct tttggcctga attttttttt aatttttaaa ttaaacacca acgaaaacct 60cattttgtct aagcagattg aagagaaaaa atgagctata ctgatagaag ctgaaaaaag 120aaattactgt ctacacgact aagaaaaaga ccaagcaagt gcaatgagta ataagttata 180gaaatagcag caactccaca agaaactgat aagcatctgc cactatcaac tctatgctag 240atgccaggca tacagtgaat gtgatgtgcc cacttcattc aagaagctca tcaggtggga 300agaccaatga ggtatcagtt taaggtatga ggatgaattt tataggaaag caggcatccc 360aaatgttccc ttatttcc 378 276 421 DNA Homo sapiens 276 ttttaatgtaaaaatcaatt tattatacaa caatcataga taatgctttt tatctacaaa 60 gaaaaatggcttctgcagcc tccctgtcta ctccattcat gatactatgt tcttaagata 120 taattactttcaaaggaaaa caaagcgata tccatatttt ccaaacaagg aagcccccag 180 acacatttatgaacgatatg gaaatattgg aaagaactca aatggactcc tagatacaaa 240 aggctgttctgcccatcaca gtaaacactg ttttgcctta aaataaaaat aataaaatat 300 ttctcaaatgcaggggtgag gactttaccc cgtaacatgc ctaagtggtt cgatatataa 360 ttttgatggcttgacaattg ctatgtttaa ttcccattca gttaacattc ccattttggt 420 a 421 277 227DNA Homo sapiens 277 aaggatagtc ttcactattt atgtcaggaa ttcctacaaactttctatgg tgaacagaat 60 agagcttcct agcagtcaat gcaaagaaga aacacaacaattccacaccc caaagttaac 120 agtcttgctt atcagaagca caggtagttc tgaaatctgatagaaaatgt tcctgtatca 180 tttcagaaca cgcaactatg tgatcaaacc cctttctatttgtttaa 227 278 213 DNA Homo sapiens 278 gaggtttctg aacacaacctttatttgatc attttagtat atattttttt gcccattcgt 60 atatttattt caccaggtcagaatacttac aatgcatcaa gcttcatgtg aattaccagg 120 aattcacaaa tgtataaaatatcaaggaac ttagcatcta atgagggaga cacatgtaaa 180 taaataaagt ttaacttacgtgatacataa agt 213 279 286 DNA Homo sapiens 279 cattatttga ttacagatacttatcagctt aaagacttta tatgctttag attaattgca 60 caacttacat atcagggtttctgattgaaa ggaagagaat attcctttct tttagtgatt 120 gcttaatatt aattcataataagtgcacca tctcttgctc cttataaatg tgtttagaag 180 aaggaaattg agtgttgggaattaagcaac caggagacat ttttatatac tcctacagtg 240 ggggaagact tcctattttctttcccaagg atggatacat ttctac 286 280 267 DNA Homo sapiens 280 gatttaaaaatttttttatt caaatattaa ttttatcaaa tgaaacaaga atctttgatg 60 atactttgatgtaaaaaaat gtttcattca tgtgtttgca ctttccatgg tttaatttgt 120 ttagggtaaattgtccaacc tgaaatataa attatccctt tgcttaatat actctttatt 180 tcttcagaaacaaaaaaaag gtaggaatta gttcaaggat gtcaatttac tgtttctagt 240 actaaagtacggctaactat gtaattt 267 281 172 DNA Homo sapiens misc_feature n=a,t,g orc 281 ttttccaact nggaatcgtt taatgtgtct acttcttcca cgcataatta taaaagaata60 agaatcgaca aaaatatttt ctttccataa tatgtagagg tggtttgttt cttttttttt 120tttttctttt ctttttactt ttttttttgc ccgcccctgg cagagctctt gg 172 282 433DNA Homo sapiens 282 taatgcgagt tagcctttta tttcatgcaa ttgcatagcatttggtttga tatactatta 60 gacattgtgt aagactctat tatgaaataa atcatctcaaaataactttt aaaaaagcaa 120 atctgttcat ctcttctgac tcaaaaggct gaaggtgaatccaaaggtac tgctaaatcc 180 aagtactaaa atgctgtagt agaaatattt ctatatcttggctctgcttt ttatactttt 240 ctttgtgtgt tggtttcatt ctcttcaaac acagacaggctttctttatc tggcagtgga 300 gttgggtcct ggcacctctc cttgagttag gaacctaagactttgaaccc ctctgtaggc 360 agggaaaatg gtggtgctat agacttggcc acgactggccagggtccggg gtcacgtggt 420 tatggctgca gca 433 283 440 DNA Homo sapiens283 aaagtcattt tattggacac aaatgctaaa aattagaaaa accatacatt ttactctatc 60aatctgttag gaaaaactat agaatatgat agtgattgca ttgattctgc ttagcaaatt 120aaatgcaaaa ctaagatatt caccaaatat aaaatatagt tattttctaa gaaataaaac 180tcacacaact gccattttta gcagaatggt ggcaactgcc atttttagca gaaaccaaaa 240ctatttcctg ttaacaagaa ggaaaaacca tcagtgaaca ctcaagtaat aatcagggga 300ctaggatgga ctctcagtaa gaaaccactg gaatatacct gggactaaat ctattctaac 360aaaattaagt ataccaaccg gaatagtttt gtgtgtgcat ttggttttta ctatatactt 420ttataatctc aaaagtacct 440 284 490 DNA Homo sapiens misc_feature n=a,t,gor c 284 ataaggaaaa ttgtttaatc agtgtaatct tatatgaaat taatattgaaaaaaaggaat 60 gttttctctt tacaaaagca tctacaagaa ttatacgaaa aacttccatgatatactgaa 120 atatataggt ccatttaaag tttttgattt ataaacaaat catcatgaatacaatttaca 180 agtaaagtaa aaagttagaa ctcagcaatt gagtttcttc agcttggattagtggtgtga 240 cagtattgcc tctgctatgc agancatagt tttcctttgc attttcccaggctttctcac 300 agacacagcc accttatctg tacccacaca gaaatgcttt gttatgtggcaacctgcaat 360 tccccagagc aggtaaggcc aagctccctt agaactgccc atttgacaagccaatgatat 420 taaagatggc tctcgcntgg gtccccactc cacattttgc acattcctctaccataacac 480 ccacatacgt 490 285 285 DNA Homo sapiens misc_featuren=a,t,g or c 285 ggtgagaaaa ggcttgtgat tttatttaat aataatttca aaatcaaagtaattagaaca 60 agtctagctt taactgaatg ccagagatta ctgttcactg tgaaattgttaggataagcc 120 tgtatttcnc tttttctcct ttgatacagt ttagcaagag cttaatcatcacttggtcgg 180 tgataagcaa gcatcttgac attttgctca taccagaatt tatgagtagctacagaaagc 240 atgcgntttg tactttgctt caaatatggg tcatccnata actat 285 286417 DNA Homo sapiens misc_feature n=a,t,g or c 286 aagagagaga gggacctcaggaaattaaat gtttcctatt tctacattaa tgctgtgtat 60 aataataatt cctttggtgcccatatgcca agcggcaata tagcaatggg caatatataa 120 aatacacggg tccttgtaagtatattttct tttctctgta tttaaaattg agattctaac 180 gtacagtttg caagtgagagatttctttat tgaaagtaat tatcaacttt ttcatttttt 240 actttgataa aatcctaactgaacccattg ccctccacct agcatgtcat gttatgttgt 300 ctattccaca ttctaaatagaggcaaaatc tcagcacttt ttaaagtgca agttcaattt 360 ctttgcattt tttcatgctgcttccnaaca tanagctgtc taagagaggg taatgtg 417 287 420 DNA Homo sapiensmisc_feature n=a,t,g or c 287 tttttttttt ttttttaatg tttcaaccattaactgttta ttataataat aatgnaaata 60 agcttttgta tctaaaagga tactatatggttacaaacat gttacctatc gcattaattt 120 tactaatccc cttttaacct tcctccatatttctttcaaa gatatttctc atactatctg 180 tttgagtcta tcaaatttct ctgaggtactcactcatttt caagcaatgt atatcagaat 240 ttgaatgntt tataacaaca tgactaagcaagatgntact aaaatccata tgggtcagta 300 acatacaana aacctggatg aaattattttttaaaaagat tatattccca caggagtttc 360 agtttccnat ttccttaatc tatgtatttatatacntaca tacaatatag aaaaggttga 420 288 349 DNA Homo sapiensmisc_feature n=a,t,g or c 288 tncaccttta aataaaaata ctttattcattcctgatagg ttatcaaaat gtacactgtt 60 aaccaagtaa aaatggtatg ctgaaatagttaactagggc atatttgaag aatttngttt 120 acttttaaaa gaggaaaaat cacttccaatcttcccttcc acacattcct aacaagcctg 180 cactatacct gcttaaaact gaaaatataaacaattacat gggccccact tcattacaga 240 atgcattttc ctgtactctt aaaggaagctattacattng aagttacctt cctttgccaa 300 aaactttcag acaagtttac ngctcgtttatattttgtgt aactttgta 349 289 271 DNA Homo sapiens 289 taaaagtgatcatgttttaa ttatgggcta aaaatgacta atacagtaag cttgaattta 60 aaaaattaagtctaaataaa ttgctaggga attccacaat gggagtcaat gaaaattttt 120 ctctacatacaatatgatca ttaacagact agttcttatt tggaatgata aggcaaaaat 180 agtaaaaccacacttttcct ataaaaagtt acacattatc ttctgtaggg atagctatcg 240 tacatgaagaaacaaagatg tgatcactct a 271 290 448 DNA Homo sapiens misc_featuren=a,t,g or c 290 tttttacagc ctaatcattt tattgcagta tctcctatta tagatatcatgctctgatgc 60 aggagagttt tggtaattaa cataaagcgc tggtacagag acttgtatcattaagggaaa 120 cagagtcaag agcttggtta gcaacagttt cttcaagtga ctgagcccctggaaggagca 180 tgaaaaaaac atcataatta tgtttatgat gcaaatgcta agtcaaagtagcaatgatat 240 gatctatgtt gtagcaaata aggtataaca aagtcttcac agtataaataaaatgttcta 300 aaaagaaaca aatattcaac ctgttaataa attggtgaaa tgtatacagataaaaatggc 360 ttatcactgg tacaatgata tcaacatgga cagtccacat tccatacatgggaactcgtg 420 atttttaaca tttgccacca aaaagtan 448 291 207 DNA Homosapiens 291 tttgagctgg gaatgttgga ctccttttaa ttctattcca atcatttcctgtatagggaa 60 attaaagtca atgcatcaaa tgaagaccca aagaaacatt taaaaacttgtttgactagt 120 attcagtatg tgagattatt aagtaataac ttgtccacct agttaaccttgtcctggaaa 180 tatatatagg ttatttgtag ccgccac 207 292 425 DNA Homosapiens 292 tttatgatct gacatttgtt ttattaacca ttagaaaaga tttgaaaaaacgaattccat 60 tttaatagtg agacaacaca atagagctaa tcatggaata ttaatgttttgctattcggg 120 aattactaag ggggaaattt gcaggaaact ttaaggcaag aatattgcaaataagttgcc 180 aaaaatatat gcttatagcc atagcaaaat gaagatttag catgcttgtctttgctccca 240 aatattttta aatgcagctt tattaaacta taatgttttt aaaattaatacttgtgctta 300 tataaaattc agtgatttaa gtacatgata ctcatttggt cacattttctgctattactg 360 ttcggcttcc caagaatttc attcaatcag caagtttagt tcacacaaacgttaaggcac 420 agagt 425 293 386 DNA Homo sapiens 293 gtttttttttttttttttgg cagagacagg atttcgccat gttggccagg ctagtcttga 60 actcctgactttaagtgatc tgcctgcctc agccccccaa agtgctggga ttacaggcat 120 gaggcaatgcacctggccaa ttcttatttt ctaattttaa taacatttct ttctttttct 180 tgccttagtgtcctggtaag actaccagta tattgttgaa tacagatgac agagtgatag 240 atgctataaggtgacagtga ataagagtga tagggcacgc ttgtgttatt ccatacatca 300 gagtgaaagcattaagtatt tcaccattca acatggcttg cacataccct ttgtcagatt 360 caagtggttacctttccatg gtagtt 386 294 482 DNA Homo sapiens misc_feature n=a,t,g or c294 acatttctag cagctttatt tgtaatagcc aaaactagat aaaacctaaa tgcttataaa 60caaatggata acaaatagta tatccataaa aaatatacca ctcagcaata aaaagaatga 120ccaccacata taagctccat tgaagaatct caaaataatt atgcatcatg aatgaaactg 180gaaaaaaaga cattttatta ataaaatcat atattataga aaatacaaac aaacctatta 240taaatgaagg tataaatcaa tggttgcctt gagggccaga gnngggaggg agagcttaga 300aaaagggcct gaggtaaatc cgaggtgact gatatgttcn ttggtaataa ttatnatgat 360gggtataatg gtgtttttga ctaggtttgg taacccnaca ttaactcncc ttccngatga 420ccctggaggg gaccccttgg cctccaggtg ggggccgcca aatactgggg taatccaatg 480 ga482 295 447 DNA Homo sapiens misc_feature n=a,t,g or ca,t,g or c 295actaaatttt gtgtttcatt tattagttca tagcatttgg catttatttt actaaaaaga 60tgctgtggca tttccaattt aagtttaaga atactttcat agtattatga tgtaaattat 120gctataataa gtaacgttcc tttaccatta ccacaaaata atctaattat agcaattatt 180tattggtagc tgtgaaaatt ttctcacaaa atgttaattg ctattaaagt ttaatggttc 240attatataaa tataatttaa atatattaca cattccaaga taaatgtact acacaatcac 300attatttctg cccaaatatt tgaaagataa gaanaccata tatcctgatc agggaaacct 360aaaatggaaa aggtcnccga gtgagaaaaa ttattttaat ccattggaat gcnagggagt 420ggaaaaggga aggntataac nagtccc 447 296 492 DNA Homo sapiens misc_featuren=a,t,g or c 296 tttattgaca tatcactttt tattttcaga ctcctaattc atattcattattaaatagtt 60 gtgtgattca tagcagaagc atttaattaa attttagtga aatggtctttcttagagcca 120 ggaaaattct ttattccaga aatcaaaaga cgatttcctc aaacatcagaatgaatcact 180 aagtaacttt gaaccaagat aaaatagtct accattatga atccttttgaaatacaggtg 240 ttccctctcc ccattttaac aaggcttatt taattaaaac ttttggaaaattagtaaact 300 gatagactat aaattaataa gctacaaata aatagctcca aatataaacaggtgtttgaa 360 aattatatac agtcagtgta gtttcttgat ataaatgcta acactgctttgattanataa 420 gatcataaaa gctagagaaa gacacgctat taaggaaacc aataattctccttatattat 480 tctcacttag gc 492 297 551 DNA Homo sapiens misc_featuren=a,t,g or c 297 gtatttataa tacttttatt aagtatgaac tctctgatgt gtaatatgtgagcaaatatt 60 aatgactttt ccacattctt tatatttgta caccatttcn caactataaatgctttcctg 120 tacaataagt tgtgaacact ggttaaaagt tatattcttc acacttggagttttctccgg 180 tataaattat tttacctgca atcaagtgtg aaaaccattt aaaagtttttcatgttcttt 240 atatttcnag agttttgcac tagtataatt ntttttatgn ttagaaaagtttgaggtatt 300 gttaaaagca ctgtgacatc attcaggatt gtagtttcgc tccagtatgaaacatcttat 360 atcngttaag aattgaggac ttatnaaggg ctttgtgaca ttcttcacacnttaggattt 420 ctgtccagta naaattatgt gtaataaggg ttgagaactt ttaaggccntggtcacatac 480 ttcatanttg taggctttan ctccacatgg ngttccccag gtttaggaagagttgagaac 540 tgggcagagg c 551 298 445 DNA Homo sapiens 298 ttttccattcagggtatttt attttcttaa agtagacaac ctttgacttt catccaatcc 60 ccagcttctctttcccccgt acatctcttc acgtccttgg ctgtgattcc gcacactgac 120 ctcggacacacagctactgc acggagagag ggagggagat ctggcaaggg ctccggcagt 180 gcctctccttctccatggcg cagtttgtat ttacacacgg cccttggcga acgtcctttc 240 aacgcagttgcccataggcc ctgggacagg aaggcccaga tcagggtccc agcagggcct 300 ccctcaggccacaacgctgg ctgtgccttc acaggagtca gagcatttcc agccagtctc 360 aggcgcggggcatgctggga ccaggggcac accccttgct ccccttcctt cactcagcaa 420 agccacaaataatttactct ttaaa 445 299 383 DNA Homo sapiens misc_feature n=a,t,g or c299 aaaggactat gattttaatt tattaaattg ctaggattgg tagttttggt gtcattaaaa 60taaataacat ctccccttgt tgctttcttt ttggttgtnc tttttctgca ccgcgaagga 120aatacactga ctattcatag ttctcagtct cagaatgagg ttttgcagca tctatacttt 180tcagcatttc ggttacatga tgctttcttg ctttgtgcaa accttgtagg gtacctggga 240aaaaacatcc acttgaggtc attgcccttt acagctcttt acaattacat cagttttgaa 300ggaacgccat ttaaatttgg tgtcagtgct cagcaagtgt aaggncgcag agtggaccag 360cagaatgctt acaagtcttt tca 383 300 394 DNA Homo sapiens 300 ttttttttcattcaacaaac atttattagg ctcctactgt gcgtcgcgct ggaaaggcaa 60 gcagaagctagattcccaat cgatcccggg aggctggacg atccagacac aaacaccgtt 120 catgcgtctattcgaaaagg ccctcttgga attttgtgca cagcatttcc ttggggtgtc 180 gatggatcggggtctgcaaa cattagcacc ttttccggtg gccgccgtct tctcagacct 240 cagacaccggcgcctccccg tgaactcccg caggcgtccc tagcccaggg cttggcgggc 300 gctgccggttgtacctggcc taagccacgc tgggccgcca gcccggggcg acaccttctt 360 cggacggcggggatttgcgg ctcgggtgac cgga 394 301 331 DNA Homo sapiens 301 ttcaaatggaaaaacttgtg gtatattctt tggaggatat actaggacct gagaagcaac 60 atgttcctggttggtaggtc cacaaaaaat ttaaacatgt agaattttat ggactgacaa 120 aaaaaattaccaatttaagt gatcaatata ttaatggttt tcagagtagt acccgatatt 180 tgatgttcaaggttcatgca tgtgtatttt taattcctta aactagacag caaggtataa 240 gtcaccattctcctctaatt tttgaaataa tcttaaactg cgcaatccag attctcgctc 300 tccatttttccacaaaataa tgagatgatc a 331 302 425 DNA Homo sapiens 302 ttttttttttttttttttca ggttttcaag cctttttttt attagaaagc ttaaattatt 60 agctttttttttaaaaggga gtagccaata tccatttttg agttttctca aacaaataat 120 aaggatagcaaactaggata agaaaacaca ttagaagaca gccttctact tcgtacaact 180 tctagttaccttttcctatc cattcaccta cttctgttca gcagcaagaa aaaaaatcca 240 tttatttttgcctttttgga tttttccaag ataaacttca tttacctgaa tacaaacaaa 300 agctagggagatggctttta tattggcata gaccaaggac atgtctcaca aaccaggaaa 360 ccctgcctcgtatggcttat tttgcagttt ggagtccaat ggttataaaa ccaagtgaaa 420 gtcga 425 303277 DNA Homo sapiens 303 caaaaagact tatttacaag ttgagcatgt catctcaattcatagcatgt agaaaaagct 60 aaaaatgttt tggagatata aatttggctg gacgactcacctacagtata ttcagggatg 120 tcttctgtac agaatatata caggttggga ctggcaagggaaatcctatc tcaggaaggc 180 gatgaacacc accacagagc cacagaccct tagcaatgttccctggcttt catttgcagt 240 tggccttgtc tctggacaga gtttgatgtg ctgggac 277304 281 DNA Homo sapiens misc_feature n=a,t,g or c 304 gatcgcgccactgcactnca gcctgagtga cagagtgaga atccatctca aaaaaagaca 60 aaaaacaaaattgcttgcta aagaagtggt ctcctgaggt cttaagacat tcctgacagt 120 ntcttgagtgggtggnagag aggttgctgt cattgcnctg tggaatttca cagatgagac 180 cacgcctagccaaaatcact tttcctgttt gcctcagtga cacagttcag ggccctcgtg 240 gatgttgtattaaataaatt nnacctntac tntttgccaa a 281 305 473 DNA Homo sapiensmisc_feature n=a,t,g or c 305 gtggctttaa aaaacacaga tttattcttttagaattttg gaggctggaa gttcgaaata 60 aatttcagtg ggctaaagtc aaggtgccagcagggtcatt ccttctggag gttctagagg 120 agaatccatt ttcttccctt tctatctacaggctgtctng cattccttag tcatgtatcc 180 aaaggccctt ttgccatata aggtaacatagttacaggtt ctggggatta gagaatggat 240 acctttggaa ggcatttttt cagcctcccacaggggactt tctcattcac cttgagaaac 300 ataaatagtt gttgaaaatg catttcagttacctccttca cctctgctca gcccttttct 360 cttccccttg ggtgggaaag caggtctgcagagacccagg ggtcctgaga tgggtagaag 420 gagaagaccc cacacagagg cgctggggcacatgcaccca ggccactcct tgc 473 306 469 DNA Homo sapiens misc_featuren=a,t,g or c 306 gnaccgcctt ccgctcgggc tgtccggcgg cggctgctac cgccgcgtgtccgtcaaggg 60 tgccgcggga tgtgtgtcag tttacgcctc tgagatcaca cagctgcctggggncgtgtg 120 atgcccaagg aagntcttgg ttttaattat tattattatc attattgttacgcttggctt 180 tcgggaaata ctcgtgatat ttgtaggata aaggaaatga cactttgaggaactggagag 240 aacatatatg cgttttgttt ttaagaggaa aaccgtgttc tcttcccggcttgttccctc 300 tttgctgatt tcaggagcta ctctcctcct ggtgaggtgg aaattccagcaagaatagag 360 gtgaagacaa gccaccagga ctcaggaggg aaacgctgac cattagaaacctctgcataa 420 gacgttgtaa ggaggaaaat aaaagagaga aaaacacaaa gatttaaac 469307 487 DNA Homo sapiens 307 tttgagatgg agtctcactg tcacccaggc tggagtgtagtgctgcgatc ctgactcgct 60 gcaacctcca cctctggagt tcaggtgatt ctcctgcctcagccttccga gtacctggga 120 atacaggaat gcaccaccat gcccggcgaa tttttctattttcagtagag acggagtttt 180 gccatgttgg ccaggctggt ctcgaactcc tgaactcaggtgatccaccc gcctcagtct 240 cccaatagat tagatatatt attaatgaat tgcttcctttaacaccctat tcattgaatt 300 ttccagtaaa ccacaattac taattactcc tgaaatcagaaaagaggtta aaaagatttt 360 ataacagtat cctatgaaat ctactacttt caagtaatagtagttgaatt accaaaaccc 420 gtcactcaag ccaatgacta caattaagat atgagtaacatttcctaaga taataaagtc 480 aattaat 487 308 263 DNA Homo sapiensmisc_feature n=a,t,g or c 308 acaacacatt ttatttgcaa aaactcagctaagagatagt ntggagctgc cacnccctgg 60 ggggctgagc tgaggtgggt catgagagagcttagtcatg ttggccctgg gtngggcagg 120 ggtggtgggg acagggngtc cagtgtctacctcacnctac ccctaatact gatcagagtt 180 tggtcccagc tgggccaagg gcaagaagagagaacgaggc caggccaatg tcttcaatcc 240 cagcggctag gaacccttca cct 263 309470 DNA Homo sapiens misc_feature n=a,t,g or c 309 tttttttttt tttatatagctttaatgccg caaaatattt atttttcctt aaaaaaggtg 60 tcaacttgga aataatggtttaaaaacagg ataagcatta aggaaaaaca ctttcaatgt 120 gtcttccatt tgatgaatttgtttttctct ctttatcccc gcaagtggag tttcatgtcc 180 tcggtgaaac cagacagtgtgaatctgttc cagcccaaat ctgcagcatt agggatgagt 240 tctcagaagt gattctgaactgagcacgca ctcatgtctg catggggaac tctggggaga 300 agagccttcc ttttctttcccttgggccat ttgcctttcc ttgtcgtctt actgagggcg 360 gaggcaggga gggtctctgtnctttccagg gccctgggca gggccatcct ggccattcag 420 ggaaagatgg gaagagttagggnctccgtt ttaggcagcc ntgggtggga 470 310 438 DNA Homo sapiensmisc_feature n=a,t,g or c 310 gacatggagt ctctcactgt cctcaggctggagtgcagtg gcgcgatctc ggctcactgc 60 tatcacttcc tttgaccacc agagaccagcccagccgtta gccagaaggg cctgggctgt 120 tcctcctgcc tgggaaggaa gactntccacacccttcagg tacctcctca gtctttctct 180 tagaggcctc cccggatgtc cccacactaggccaggtntc cctgtagact taccacagtt 240 gtaattataa gtgtgtttgt ttagtgcctcccccacccca tactgggact ntaaagcctc 300 cagagcaggg ggccatgggc aacctggggtntccagtgct gggacgcctg gggagggtat 360 ttcttcttca atattttctt tgaatggaatttcacaaata ttttaatgga tattaaaagg 420 gaaaaaggat aaagttgc 438 311 431 DNAHomo sapiens 311 atagtaagaa cccaatttta tttagaaacc agcaagcagc gtatgcagttaagaacccaa 60 ttttattaca atttgtacat aaatgcccag gaaaagttgg aaggtgctacattaaggtgt 120 taagagtcgc catgggggtg gctgatgtga gaatttaagg tgttttctctttaggataaa 180 atatcctacc gcccccagga gtgaccacgt gaggctgcat aatggccgtctctgtgtctg 240 cagtgatgtc tgcagtgacg aacgcccggg gtggtgagct ctaatggccttctctgtgtc 300 tgcagtgatg tctgcagtga cgaacgcccg gggtggtgag ctctaatggccgtctctgtg 360 tctgcagtga tgtctgcagt gacgaacgcc cggggtggtg agctctcgactttagagaga 420 gaattgcatc c 431 312 336 DNA Homo sapiens misc_featuren=a,t,g or c 312 ggtgacacat ctccttttca cgtttatttc attttgtttt aagatcacagaagagcagag 60 cattcatacg tgtaaagtaa cagaagagag aaacagaatt taaatacatttaaaaagaaa 120 agaaaaaaag ctttttttca ttttaatttt aatttttttt ttttaacacacattgcgctt 180 tttatctcct tcacagagct agtacccagg gaaaaaaatc cacctaataaacaaaaatga 240 aaaaccttga aaaacaaaaa atcccaaaca aaaaatggcc atgtgtttgtatcttcaagg 300 gaggntcagt ttcatgtcta cagggctgaa aaaggg 336 313 465 DNAHomo sapiens 313 tttttgaagg cacacaaagc tttattggct ccgttccagg caatgacatcagtgtggggc 60 tcttgcctgc tcccatctgt cttctcttgg tgggtcttca ggggcctcagggtctatctc 120 acctgcgctg tgtcctccca gctctccctc caacaggggc catcttctgtggcagacccc 180 actcatggag tttaaagagc ccataatccc cgtgaggagc ctaagaaagtagggatttgg 240 gcacagcatc tcaccctggc ctgcatagat ggccccatag gagagaaaacagacgtgtgt 300 gtgagccagc cttgctgggg gcaggggcgt ctccatccat ggttaggtggcttccaagaa 360 gtcacagatc tagtgtctgc gattaggcag gctgtggctc tggtggcttgggtggccatg 420 gtgactgtgg tgactgtggc catagaaggt gtgtgtgtga ttggc 465 314437 DNA Homo sapiens 314 tttccataaa aagcactttg tttaatttta tcaaatcgatctgtacaaaa gttagcgttg 60 cttggtcaga aaggagtgaa ggcagcaggg gagtgagggtgcgtcctccg aacgcggtgc 120 caagggagac gctgcatgaa acgggtctgc gacggctcccggcccccacc cccaccccca 180 gagaaataga agcagaggca ttatcttttt tttctacaaaaaagtaggaa aagtagaaaa 240 agtacaaaga agcaacttct cggctgtgtt taagtttacaaagtttaaag gcacaagttt 300 ccgtgaagta ggcgctattg tatgctctat gctcagcacacaggggaagc agtgcaggtg 360 aatcaggtat gactcgtcta gaactgaggc cctaacgacgtttagtggag aaggtttagt 420 ttcacagctt ggtaggt 437 315 367 DNA Homosapiens misc_feature n=a,t,g or c 315 gaatgctctn acctttattt ctctnaatatacccgtnata cagatatttn atatgtaaca 60 aagataagga cgtgtgcagg tataaaacagaggcagantc atggctaaaa catctagccc 120 agcaatganc tcattatccc tgaggggtaggggcggggna ggagaggagt cacaggcngt 180 tcacccacac ctggaaaanc gatgacttcanggagaatga atnnctcggg ggnnttcagn 240 tcatgaagtc atnagaagaa ggcctttcttcccagggatg atgtttctca gtatcaataa 300 tcagttgtgg gtttttttct tctatttcttccagcagctt tattgagttc atcattaaag 360 tcatcta 367 316 5588 DNA Homosapiens 316 ccctcttcct tacctagtcc cttgtctaat tgatcgtgta atagtacacttccccagaca 60 agtccacact aatataagaa ccaaaacatc cctccccttc tttttttggcaacaaggaaa 120 actacccaga cctgcgatcc attgccgaaa ccctctctcc agagccctcatccttccggt 180 ctgtgtggaa ttccgaattg aatcattcag tttggtgcta taaaacccatacctaaagac 240 tcgcggttat attatccatg aagaatccca acaacactct taacttctaataattaatat 300 ttcacggacc caaccacgaa ccggtagtat ttgttgaggt atttacgagcgaaaatgaca 360 gcacctatgt gcctccaccc tctgggttaa cccaagggcg ggtacaataacccggggtgc 420 cgatatacca gaaatgccga aggatcagag aagtggtaga gattccaaacaaaggagtag 480 acttagtgtc cactcactaa gagtcccact gagttctccc gaccacgtcaccgtctcgta 540 cccttagctc ccttccgcgg aaggacagtc tccgttgtgt gggtcaccctcctaggacgg 600 gcgagacgag agaggatgga ggggaagggc ccgatttgcg accccagccagaccgtcgat 660 aaggccctta gactcgcgcc taagactgtt tcctctgcag aaggtggctggtgtagtgta 720 cctcgaggtt tcgtgctcgt gccggagggc cccgacactg gagttccgcctcggggacca 780 ctggagtccc tctcaggggt gggggcgtcg ggcacggggc cccgtcccgcccccgtccct 840 ctcccccgcc ttagccccgc cagggccctc gcggggcggg ggaggcggaggcgtcgcaac 900 tggacgtcga cagccgcccg ccaccgagag atcagctgtc agagatcagaggaagaggaa 960 ggggcggagc tgctttgcgg ccggccggag cagtcagccg actacagagaagggtaatcg 1020 ggtgtccccg gcgccgcccg gggccctgag ggctggctag ggtccaggccgggggggacg 1080 ggacagacga accagccccg tgtaggaagc gcgacaatgc cccgctacggagcgtcactc 1140 cgccagagct gccccaggtc cggccgggag cagggacaag acgggaccgccggagccccc 1200 ggactccttt ggatgggcct ggcgctggcg ctggcgctgg cgctggcgctggctctgtct 1260 gactctcggg ttctctgggc tccggcagag gctcaccctc tttctccccaaggccatcct 1320 gccaggttac atcgcatagt gccccggctc cgagatgtct ttgggtgggggaacctcacc 1380 tgcccaatct gcaaaggtct attcaccgcc atcaacctcg ggctgaaggtgagcactgaa 1440 ggggctgcag tggaggaggc cgaaaggagt gctggggctg ggggctggggctgatgctgg 1500 tgcgctgggc tcagaatgca tccctgatgg agagggtggc atctacaatccatcactgag 1560 tttgctcccc tttggggaca cccatggcta catgccacca tcaccccattgtgacctttg 1620 tgaagtaaga aataatgcag acagtgcctg aggaagtcag cttgccaagcaaaggcctca 1680 tgccacaggc cgctgagcta aagaagaagc gatggcctgg tgctgcctgagttacagggc 1740 aatatctgga aggcaaaggt gtgcactgag cttggtgcac tgagtcctgcccagccccag 1800 tttggaaatg gaggccaagg ggtggtggcc aggggttggc ctggttcctctgctctgcct 1860 ctgatttctc accatgcgct cctcccactg cagaaggaac ccaatgtggctcgcgtgggc 1920 tccgtggcca tcaagctgtg caatctgctg aagatagcac cacctgccgtgtgccaatcc 1980 attgtccacc tctttgagga tgacatggtg gaggtgtgga gacgctcagtgctgagccca 2040 tctgaggcct gtggcctgct cctgggctcc acctgtgggc actgggacattttctcatct 2100 tggaacatct ctttgcctac tgtgccgaag ccgcccccca aaccccctagccccccagcc 2160 ccaggtgccc ctgtcagccg catcctcttc ctcactgacc tgcactgggatcatgactac 2220 ctggagggca cggaccctga ctgtgcagac ccactgtgct gccgccggggttctggcctg 2280 ccgcccgcat cccggccagg tgccggatac tggggcgaat acagcaagtgtgacctgccc 2340 ctgaggaccc tggagagcct gttgagtggg ctgggcccag ccggcccttttgatatggtg 2400 tactggacag gagacatccc cgcacatgat gtctggcacc agactcgtcaggaccaactg 2460 cgggccctga ccaccgtcac agcacttgtg aggaagttcc tggggccagtgccagtgtac 2520 cctgctgtgg gtaaccatga aagcacacct gtcaatagct tccctccccccttcattgag 2580 ggcaaccact cctcccgctg gctctatgaa gcgatggcca aggcttgggagccctggctg 2640 cctgccgaag ccctgcgcac cctcaggtac ttatcgtccg tggaaacccaggaagggaaa 2700 agaaaggtga atgaaagtga agggagaagg gaacctgggg cattgtctctgattgctcta 2760 gcatgagtcc ttagtgctct tcatttggct cccctaatct gactcctccttccctttcta 2820 ctgttttgcc gcaccaggct tttttttttt tttttttttt agtttagtttttgtagagac 2880 aagatcttgc tatgttgccc aggctggtct caaacaccta acctcaagcaatcctcccgc 2940 ctcggcctcc caaaatgctg ggaccacagg catcagctac tgctcctggccctccctttt 3000 tttttttttt tttttttttt ttttttgaga tggaatcctg ctctgttgcccaggctggag 3060 tgcagtggca ccatctcagc tcactacagc ctccacctcc tgggttcaagcaattctgcc 3120 tcagcctccc aagtacctgg gactacaggt gcacgccacc acacccagctaatttttgta 3180 tttttagtag agatggggtt tcaccatgtt ggccaagatg gtcttgatctcctgacctca 3240 tgatctgccc acctcggcct cccaaagtgc tgggattaca ggcatgaaccactgcaccca 3300 gctttccagc cctccctttc tactcttatc tccagccacc ctccttcaaaggtctggcag 3360 cataacctct ctatgcccca gctgtgtctt tgctcatgtt ggccctctggaaatgatttc 3420 cccctttttt ttaagtgctc cagttttttc ccaccttatc catcccatgtcatcttccct 3480 ctgtgtggtc cttgcttccc attctagcta actcttatcc ctcccccatactcctggagc 3540 cctctgccct cagagtcttt tgtgtcacac agacccaata attagaactgtttggtctct 3600 ggctagactg tgagctcctt gcaggtgggg aagatgtcat gtatgcttttaccctccacc 3660 caaatgccca gcacaggagg accaggattg gaacaagtgt tgacctctcatgtttacttt 3720 gtttcagaat tggggggttc tatgctcttt ccccataccc cggtctccgcctcatctctc 3780 tcaatatgaa tttttgttcc cgtgagaact tctggctctt gatcaactccacggatcccg 3840 caggacagct ccagtggctg gtgggggagc ttcaggctgc tgaggatcgaggagacaaag 3900 tgagggccag tagtgggaac acggtggtgc tgggggacaa gcaggctcctgttgagctgg 3960 agcacctctg ggcacagaag ttttattttc ctggcattcc caacaagtgttccctgggga 4020 ttcagctcat ggtcactgtt gaaagccttc attcagtccc cctttctctagccagggctg 4080 cctggacccc tggatgccct gattaccatc cttaattctc cctactaggtgcatataatt 4140 ggccacattc ccccagggca ctgtctgaag agctggagct ggaattattaccgaattgta 4200 gccaggtagg acggagatga gggtgggaat agggacaggg tgagtgtctgaaggctgaaa 4260 attcccttga gcatctcacc atccctgttg tcccatggag tggggaggctcctcactaga 4320 acaggttgga gaaagagggc atcctatctc cccagatgtc ttcctacccctccctagaat 4380 cttctgaatg tagtaccttc tggccaggta tgagaacacc ctggctgctcagttctttgg 4440 ccacactcat gtggatgaat ttgaggtctt ctatgatgaa gagactctgagccggccgct 4500 ggctgtagcc ttcctggcac ccagtgcaac tacctacatc ggccttaatcctggtgagtg 4560 aggcagaagg gagcctccct tatcctggag ttggtgggat aggggaaggaggttggagcc 4620 agagcctgca aagcatgggc aggatgtgtg gcccctccct ggagttacccttgctccttg 4680 cccctccagt cagccccaca tccttgcagg ttaccgtgtg taccaaatagatggaaacta 4740 ctccgggagc tctcacgtgg tcctggacca tgagacctac atcctgaatctgacccaggc 4800 aaacataccg ggagccatac cgcactggca gcttctctac agggctcgagaaacctatgg 4860 gctgcccaac acactgccta ccgcctggca caacctggta tatcgcatgcggggcgacat 4920 gcaacttttc cagaccttct ggtttctcta ccataagggc cacccaccctcggagccctg 4980 tggcacgccc tgccgtctgg ctactctttg tgcccagctc tctgcccgtgctgacagccc 5040 tgctctgtgc cgccacctga tgccagatgg gagcctccca gaggcccagagcctgtggcc 5100 aaggccactg ttttgctagg gccccagggc ccacatttgg gaaagttcttgatgtaggaa 5160 agggtgaaaa agcccaaatg ctgctgtggt tcaaccaggc aagatcatccggtgaaagaa 5220 ccagtccctg ggccccaagg atgccgggga aacaggacct tctcctttcctggagctggt 5280 ttagctggat atgggagggg gtttggctgc ctgtgcccag gagctagactgccttgaggc 5340 tgctgtcctt tcacagccat ggagtagagg cctaagttga cactgccctgggcagacaag 5400 acaggagctg tcgccccagg cctgtgctgc ccagccagga accctgtactgctgctgcga 5460 cctgatgctg ccagtctgtt aaaataaaga taagagactt ggactccagacccctgtgtg 5520 actgtcccaa tttcttcttt ccaggcaagc agggcaagga gatctttggagcaagatcat 5580 aactgagg 5588 317 2337 DNA Homo sapiens 317 gagctcagagaggagagagt gcacatgcag ccgacagtgg cagggcagga ccaggaagtc 60 aggcagtgtgacttggggga tccatgctta ttctcctccc acctttcgga aggcacagga 120 aggcaccacagtgtcgcaat ttatgcacaa ttagtgcaaa gtctcacctg tgagcttgcc 180 tggggcaaccaggggaggct gggggctcct tctccaccag gccccgctgc ctccatatga 240 ctcttccctgtattttagcc ctgtaggtaa ttttccagtt tgtgggctcc tgtaccacat 300 gcggtgagttaaaagaacag gtgggcagcg gcgcggctcc cgcgtgagct gtgtgacttt 360 gagcaggccccactaccttt ccgagccgca tttccacctg ggcgaagcgg gttgagccgg 420 cctggcggggaaagattctt ttaacggggg aacaacgtaa ggcgtgcacc ggggaacacg 480 gatgctgctgagtcaatgcc cgctctgccg ttctctttga gagtaaggct tgcgtctcgc 540 ctgctctagcgccccaggtt tgaacgcagt gggcgcgcag gaggaaacat agattcacga 600 atgcaatgccagcaaagtaa aatttttcac ccttgtccgt ttttcagggt gtttcaagcg 660 gaggagtcctgagtggagaa gattccgctt ccctgttttc aggttctggc agtcatggac 720 cgggaagagcgagtcggggc gcgggtccct ggcggtcgct ggaacccttg tgagtgaggt 780 tggtgcccgcgagggcacag cgggcgctcg ggaagtcgca gccgccggca gagggcgccc 840 cgggcacacggagcgcgcgg cgctggggtt ggggcgctcg ggaggtgcgg ggcaccggct 900 ggagtccggcgttgaccgca gccgggacgc gcccgccacc tgggcgggga aggagtgagt 960 cccctcggggcgcagcggcg cgcgctggcc cggatcccag ctgcgccgcg ccctccctgc 1020 gagcggtgagtacaggcgcc cacgggcatc tccaacccta gttaggggac acttggagac 1080 aacgcaggtcggacgtccgc cggccgttct aggagttggt gtgcggggaa tggggggtgc 1140 tcccgctcgcttagggcttt gggtccggct aggggttgac cccaagaggc gctggatgtc 1200 ggggctgagctttgctttca ggggactcaa gcttacttga ggttctgaca ttggatttgc 1260 ctcgcgggcccctgcgcgtg ctgccggggg atccggagac tggcgaggta accagggagg 1320 gcaagcactcaccggggcgt cctccgccca cctcgcccgc agaaccatcc agggggacca 1380 cgtgcggctgtcgcccgcaa ctctgcctgt caagcgagga ccgcccccag ggcaggggag 1440 gggacgcgcgggcggggtgg gctgtgcccc gcgggaaccc cgccggcctg tgcgcttgct 1500 ggtgccagctcggctcgctg cctcgcattg ccacaggctc ctgagaggtc gcgggcagtg 1560 cctgcggggaggcgcggggc cctgctctgt agggctgaag gccgcccgag gttcgccaag 1620 gctctgggctctcgaaagga agccaagaaa agaagctgcc caggtgacca gtcctgggag 1680 tgctctctcccaaggaagct ccgagcgccc aggagccctt agccggggtc tagtgccctt 1740 tgaacaatctccagctcttc aaggaagtgg gctgccgccg cctctcttgg gacctggcct 1800 gggatcctttccccaaacgc accccggcga tttttgcgca ccgggagccg aacccctgct 1860 gcgcgcagctggctgggctc aggcgcgctt cctcaacgtt tcggagccgc tgcccccagc 1920 gaagtccacattccaagctc caggggcttt gagagagacg accccaaggc aaggtaggtg 1980 gctcggacgggctcgccctg ggaattatta ggttgggctt gacgtgagta atgatgccat 2040 ctgcttaagtcttggagaaa gaccgtgtgt tttccttttg ctttttaagg cgtttggaga 2100 gctgctgaggagccaggggc ttggaggagc gagaagacat gtattttcag ctgagtctca 2160 gaaggggagaatctcctgtc accaccagaa aagcaacagc cccgaaatgt gattgcaact 2220 gactagcagagcagaggccc aggagtcact ggattgatga tttagaatat gctaaaaagc 2280 cagtgctttatttggggaat tcaggggctt tctggtgccc aagacagtga cctgcag 2337 318 748 DNAHomo sapiens 318 cctagcagtc aacatgaagg ctctcattgt tctggggctt gtcctcctttctgttacggt 60 ccagggcaag gtctttgaaa ggtgtgagtt ggccagaact ctgaaaagattgggaatgga 120 tggctacagg ggaatgagcc tagcaaactg gatgtgtttg gccaaatgggagagtggtta 180 caacacacga gctacaaact acaatgctgg agacagaagc actgattatgggatatttca 240 gatcaatagc cgctactggt gtaatgatgg caaaacccca ggagcagttaatgcctgtca 300 tttatcctgc agtgctttgc tgcaagataa catcgctgat gctgtagcttgtgcaaagag 360 ggttgtccgt gatccacaag gcattagagc atgggtggca tggagaaatcgttgtcaaaa 420 cagagatgtc cgtcagtatg ttcaaggttg tggagtgtaa ctccagaattttccttcttc 480 agctcatttt gtctctctca caattaaggg agtaggttaa gtgaaaggtcacataccatt 540 atttcccctt caaacaaata atatttttac agaagcagga gcaaaatatggcctttcttc 600 taagagatat aatgttcact aaatgtggtt atttttatat taagcctacaacatttttta 660 gtttgcaaat agaactaata ctggtgaaaa tttacctaaa accttggttattaaatacat 720 ctccagtaca ttccgttctt tttttttg 748

What is claimed is:
 1. A process for identifying an agent that modulates the activity of a cancer-related gene comprising: (a) contacting a compound with a cell containing a gene that corresponds to a polynucleotide having a sequence selected from the group consisting of SEQ ID NO: 1-318 and under conditions promoting the expression of said gene; and (b) detecting a difference in expression of said gene relative to when said compound is not present thereby identifying an agent that modulates the activity of a cancer-related gene.
 2. The process of claim 1 wherein said gene has a sequence selected from the group consisting of SEQ ID NO: 1-318.
 3. The process of claim 1 wherein the cell is a cancer cell, the sequence is selected from SEQ ID NO: 230-318 and the difference in expression is a decrease in expression.
 4. The process of claim 2 wherein the cell is a cancer cell, the sequence is selected from SEQ ID NO: 230-318 and the difference in expression is a decrease in expression.
 5. The process of claim 3 or 4 wherein the cancer cell is a pancreas cancer cell.
 6. The process of claim 3 or 4 wherein the cancer cell is a carcinoma cancer cell.
 7. The process of claim 3 or 4 wherein the cancer is adenocarcinoma.
 8. The process of claim 1 wherein the cell is a non-cancerous cell, the sequence is selected from SEQ ID NO: 1-229 and the difference in expression is an increase in expression.
 9. The process of claim 8 wherein the cell is a cell from pancreas.
 10. The process of claim 2 wherein the cell is a non-cancerous cell, the sequence is selected from SEQ ID NO: 1-229 and the difference in expression is an increase in expression.
 11. The process of claim 2 wherein the cell is a cell from pancreas.
 12. The process of claim 1-11 wherein expression is determined for more than one said gene.
 13. The process of claim 1-11 wherein expression is determined for at least 5 said genes.
 14. The process of claim 1-11 wherein expression is determined for at least 10 said genes.
 15. The process of claim 1-11 wherein expression is determined for all said genes of step (a).
 16. A process for identifying an anti-neoplastic agent comprising contacting a cell exhibiting neoplastic activity with a compound first identified as a cancer related gene modulator using a process of one of claims 1-15 and detecting a decrease in said neoplastic activity after said contacting compared to when said contacting does not occur.
 17. The process of claim 16 wherein said neoplastic activity is accelerated replication.
 18. The process of claim 16 wherein said decrease in neoplastic activity results from the death of the cell.
 19. A process for identifying an anti-neoplastic agent comprising administering to an animal exhibiting a cancer condition an effective amount of an agent first identified according to a process of one of claims 1-18 and detecting a decrease in said cancerous condition.
 20. A process for determining the cancerous status of a cell, comprising determining the level of expression in said cell of at least one gene that corresponds to a polynucleotide having a sequence selected from the group consisting of SEQ ID NO: 1-318 wherein an elevated expression relative to a known non-cancerous cell when the sequence is one of SEQ ID NO: 230-318 or a reduced expression relative to a known non-cancerous cell when the sequence is one of SEQ ID NO: 1-229 indicates a cancerous state or potentially cancerous state.
 21. The process of claim 20 wherein the cell is a cell from pancreas.
 22. The process of claim 20 wherein when said elevated expression is elevated expression of a gene corresponding to SEQ ID NO: 230-318 the cancer to be determined is carcinoma.
 23. The process of claim 20 wherein when said elevated expression is elevated expression of a gene corresponding to SEQ ID NO: 230-318 the cancer to be determined is adenocarcinoma.
 24. The process of claim 20 wherein when said elevated expression is elevated expression of a gene corresponding to SEQ ID NO: 230-318 the cancer to be determined is pancreatic carcinoma.
 25. The process of claim 20 wherein a cDNA of the gene has the sequence of SEQ ID NO: 1-318.
 26. The process of claim 20, 21, 22, 23, 24 or 25 wherein said expression is the expression of more than one said gene.
 27. The process of claim 20, 21, 22, 23, 24 or 25 wherein said expression is the expression of at least 5 said genes.
 28. The process of claim 20, 21, 22, 23, 24 or 25 wherein said expression is the expression of at least 10 said genes.
 29. The process of claim 20, 21, 22, 23, 24 or 25 wherein said expression is the expression of all said genes.
 30. A process for determining if a test gene is a cancer initiating or facilitating gene comprising contacting a cell expressing said test gene with an agent that decreases the expression of a gene that corresponds to a polynucleotide having a sequence selected from the group consisting of SEQ ID NO: 230-318, and detecting a decrease in expression of the test gene compared to when said agent is not present, thereby identifying said test gene as being a cancer initiating or facilitating gene.
 31. The process of claim 30 wherein the gene determined by said process is an oncogene.
 32. The process of claim 30 wherein the gene determined by said process is a cancer facilitating gene.
 33. The process of claim 30 wherein said decrease in expression is due to a decrease in copy number of said gene in said cell or a cell derived from said cell.
 34. A process for determining if a test gene is a cancer suppressor gene comprising contacting a cell expressing said test gene with an agent that increases the expression of a gene that corresponds to a polynucleotide having a sequence selected from the group consisting of SEQ ID NO: 1-229 and detecting an increase in expression of said test gene compared to when said agent is not present, thereby identifying said test gene as being a cancer suppressor gene.
 35. The process of claim 34 wherein said increase in expression is due to an increase in copy number of said gene in said cell or a cell derived from said cell.
 36. A process for treating cancer comprising contacting a cancerous cell with an agent having activity against an expression product encoded by a gene sequence selected from the group consisting of SEQ ID NO: 230-318.
 37. The process of claim 36 wherein said cancerous cell is contacted in vivo.
 38. The process of claim 36 wherein said agent has affinity for said expression product.
 39. The process of claim 38 wherein said agent is an antibody.
 40. The process of claim 36 wherein said agent is an apoptosis-inducing agent.
 41. A method for producing a product comprising identifying an agent according to the process of claim 1-19 wherein said product is the data collected with respect to said agent as a result of said process and wherein said data is sufficient to convey the chemical structure and/or properties of said agent.
 42. A process for treating a cancerous condition in an animal afflicted therewith comprising administering to said animal a therapeutically effective amount of an agent first identified as having anti-neoplastic activity using the process of claim
 19. 43. A process for protecting an animal against cancer comprising administering to an animal at risk of developing cancer a therapeutically effective amount of an agent first identified as having anti-neoplastic activity using the process of claim
 19. 44. The process of claim 42 or 43 wherein said cancer is pancreas cancer.
 45. The process of claim 42 or 43 wherein said cancer is a carcinoma.
 46. The process of claim 42 or 43 wherein said cancer is adenocarcinoma.
 47. A process for determining functionally related genes comprising contacting one or more gene sequences selected from the group consisting of the sequences of SEQ ID NO: 1-318 with an agent that modulates expression of more than one gene in such group and thereby determining a subset of genes of said group.
 48. The process of claim 47 wherein said functionally related genes are genes modulating the same metabolic pathway.
 49. The process of claim 47 wherein said functionally related genes are genes encoding functionally related polypeptides.
 50. The process of claim 47 wherein said functionally related genes are genes whose expression is modulated by the same transcription activator or enhancer sequence.
 51. The process of claim 47 wherein said sequences are selected from SEQ ID NO: 230-318.
 52. The process of claim 47 wherein said sequences are selected from SEQ ID NO: 1-229. 